Zobrazeno 31 - 40
of 91
pro vyhledávání: '"Ethan Cerami"'
Autor:
Theresa A Harbig, Sabrina Nusrat, Tali Mazor, Qianwen Wang, Alexander Thomson, Hans Bitter, Ethan Cerami, Nils Gehlenborg
Molecular profiling of patient tumors and liquid biopsies over time with next-generation sequencing technologies and new immuno-profile assays are becoming part of standard research and clinical practice. With the wealth of new longitudinal data, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::851a47e8dbb956445c070cfb6b453ce5
https://doi.org/10.31219/osf.io/b3n4u
https://doi.org/10.31219/osf.io/b3n4u
Autor:
Minkyung Song, Sean C. Bendall, Melissa D. Bowman, James Lindsay, Diane Marie Del Valle, J. Jack Lee, Cathy Rowe, Gerold Bongers, Jenny Peterson-Klaus, James H. Doroshow, Valerie M. Tatard-Leitman, F. Stephen Hodi, Holden T. Maecker, Chia-Chi Chang, Sacha Gnjatic, David Patton, Srinika Ranasinghe, Ethan Cerami, Lyndsay Harris, Jeffrey S. Abrams, Magdalena Thurin, Stacey J Adam, Ignacio I. Wistuba, Rebecca A. Enos, Helen X. Chen, Margaret M. Mooney, Sylvie Janssens, Robert R. Jenq, Elad Sharon, Howard Streicher, Chantale Bernatchez, Mina Pichavant, Joyce Yu, Stephen M. Hewitt, Catherine J. Wu, Beatriz Sanchez-Espiridion, Xiaole Shirley Liu, Radim Moravec, Ming Tang, Gheath Alatrash
Publikováno v:
Clin Cancer Res
Purpose: Immunoprofiling to identify biomarkers and integration with clinical trial outcomes are critical to improving immunotherapy approaches for patients with cancer. However, the translational potential of individual studies is often limited by s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d123c2ad19f463e523105dab86b951fc
https://europepmc.org/articles/PMC8491462/
https://europepmc.org/articles/PMC8491462/
Autor:
Jianjiong Gao, Tali Mazor, Ino de Bruijn, Adam Abeshouse, Diana Baiceanu, Ziya Erkoc, Benjamin Gross, David Higgins, Prasanna K. Jagannathan, Karthik Kalletla, Priti Kumari, Ritika Kundra, Xiang Li, James Lindsay, Aaron Lisman, Pieter Lukasse, Divya Madala, Ramyasree Madupuri, Angelica Ochoa, Oleguer Plantalech, Joyce Quach, Sander Rodenburg, Anusha Satravada, Fedde Schaeffer, Robert Sheridan, Lucas Sikina, S. Onur Sumer, Yichao Sun, Paul van Dijk, Pim van Nierop, Avery Wang, Manda Wilson, Hongxin Zhang, Gaofei Zhao, Sjoerd van Hagen, Kees van Bochove, Ugur Dogrusoz, Allison Heath, Adam Resnick, Trevor J. Pugh, Chris Sander, Ethan Cerami, Nikolaus Schultz
Publikováno v:
Cancer Research
The cBioPortal for Cancer Genomics is an open-source software platform that enables interactive, exploratory analysis of large-scale cancer genomics data sets with a user-friendly interface. It integrates genomic and clinical data, and provides a sui
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c889071fdf7adc9d00b7cab84d9e2335
https://hdl.handle.net/11693/77721
https://hdl.handle.net/11693/77721
Autor:
Nils Gehlenborg, Sabrina Nusrat, Qianwen Wang, Ethan Cerami, Hans Bitter, Alexander Thomson, Theresa A Harbig, Tali Mazor
Publikováno v:
Bioinformatics.
Motivation Molecular profiling of patient tumors and liquid biopsies over time with next-generation sequencing technologies and new immuno-profile assays are becoming part of standard research and clinical practice. With the wealth of new longitudina
Autor:
Harry Klein, Tali Mazor, Priti Kumari, James Lindsay, Andrea Ovalle, Pavel Trukhanov, Joyce Yu, Michael Hassett, Ethan Cerami
Publikováno v:
Molecular Cancer Therapeutics. 20:P160-P160
With the advent of next generation sequencing in cancer care, patients’ tumors can be genomically profiled and specific genetic alterations can be targeted with precision medicine drugs. However, the abundance of patient sequencing data coupled wit
Autor:
Susan M. Mockus, Deborah I. Ritter, David Tamborero, Obi L. Griffith, Jeremy Goecks, Gordana Raca, Damian T. Rieke, Georgia Mayfield, Nuria Lopez-Bigas, Jianjiong Gao, Kilannin Krysiak, Melissa A. Haendel, Ryan P Duren, Olivier Elemento, Kyle Ellrott, Jordi Deu-Pons, Adam A. Margolin, Brian Walsh, Tero Aittokallio, Michael Baudis, Rodrigo Dienstmann, Subha Madhavan, Julie A. McMurry, Sara E. Patterson, Ethan Cerami, Ozman Ugur Sezerman, Robert R. Freimuth, Beth A. Pitel, Nikolaus Schultz, Lynn M. Schriml, Alex H. Wagner, Jeremy L. Warner, Mark Lawler, Jacques S. Beckmann, Dmitriy Sonkin, Catherine Del Vecchio Fitz, Xuan Shirley Li, Debyani Chakravarty, Malachi Griffith
Publikováno v:
Variant Interpretation for Cancer Consortium 2020, ' A harmonized meta-knowledgebase of clinical interpretations of somatic genomic variants in cancer ', Nature Genetics, vol. 52, no. 4, pp. 448-457 . https://doi.org/10.1038/s41588-020-0603-8
Nature Genetics
Nature genetics, vol. 52, no. 4, pp. 448-457
Scientia
Nature Genetics
Nature genetics, vol. 52, no. 4, pp. 448-457
Scientia
Precision oncology relies on accurate discovery and interpretation of genomic variants, enabling individualized diagnosis, prognosis and therapy selection. We found that six prominent somatic cancer variant knowledgebases were highly disparate in con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c37b4128ca2649aae6483eb7ae33b29f
https://pure.qub.ac.uk/en/publications/eac9e539-6ee6-4236-a0fc-64fa11bb778e
https://pure.qub.ac.uk/en/publications/eac9e539-6ee6-4236-a0fc-64fa11bb778e
Autor:
Pedro, Exman, Ana C, Garrido-Castro, Melissa E, Hughes, Rachel A, Freedman, Tianyu, Li, Lorenzo, Trippa, Brittany L, Bychkovsky, Romualdo, Barroso-Sousa, Simona, Di Lascio, Colin, Mackichan, Max R, Lloyd, Max, Krevalin, Ethan, Cerami, Margaret S, Merrill, Rebecca, Santiago, Lindsey, Crowley, Nicole, Kuhnly, Janet, Files, Neal I, Lindeman, Laura E, MacConaill, Priti, Kumari, Sara M, Tolaney, Ian E, Krop, Ron, Bose, Bruce E, Johnson, Cynthia X, Ma, Deborah A, Dillon, Eric P, Winer, Nikhil, Wagle, Nancy U, Lin
Publikováno v:
JCO Precis Oncol
PURPOSE: The yield of comprehensive genomic profiling in recruiting patients to molecular-based trials designed for small subgroups has not been fully evaluated. We evaluated the likelihood of enrollment in a clinical trial that required the identifi
Autor:
Chris Sander, Max Franz, Manfred Cheung, Qizhi Wen, Bulent Arman Aksoy, Jeffrey V. Wong, Michael Wrana, Jonah Dlin, Ethan Cerami, Ugur Dogrusoz, Geoffrey Elder, Benjamin Gross, Igor Rodchenkov, Christian Dallago, Augustin Luna, Metin Can Siper, Peter T. Smith, Caitlin O'Callaghan, Logan Mosier, Özgün Babur, Emek Demir, Wanxin Li, Gary D. Bader, Harsh Mistry, Dylan Fong
Publikováno v:
Nucleic Acids Research
Pathway Commons (https://www.pathwaycommons.org) is an integrated resource of publicly available information about biological pathways including biochemical reactions, assembly of biomolecular complexes, transport and catalysis events and physical in
Autor:
Caitlin O'Callaghan, Igor Rodchenkov, Qizhi Wen, Bulent Arman Aksoy, Emek Demir, Peter T. Smith, Metin Can Siper, Logan Mosier, Ugur Dogrusoz, Chris Sander, Michael Wrana, Jonah Dlin, Harsh Mistry, Manfred Cheung, Ethan Cerami, Benjamin Gross, Dylan Fong, Özgün Babur, Christian Dallago, Augustin Luna, Max Franz, Gary D. Bader, Wanxin Li, Geoffrey Elder, Jeffrey V. Wong
Pathway Commons (https://www.pathwaycommons.org) is an integrated resource of publicly available information about biological pathways including biochemical reactions, assembly of biomolecular complexes, transport and catalysis events and physical in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c57abd0226646b10dc11334507e2473
Autor:
Ruth Lederman, Eliezer M. Van Allen, Stacy W. Gray, Nelly Oliver, Aaron Suarez, Anna Revette, Angel M. Cronin, Lynette M. Sholl, Jordan Bryan, Ethan Cerami, Charlotte E. Lee, Jeffrey Gagan, Carol Lowenstein, Hajime Uno
Publikováno v:
Journal of the American Medical Informatics Association : JAMIA
Objective Misinterpretation of complex genomic data presents a major challenge in the implementation of precision oncology. We sought to determine whether interactive genomic reports with embedded clinician education and optimized data visualization