Zobrazeno 21 - 30
of 102
pro vyhledávání: '"Elizabeth M. Streicher"'
Autor:
Marlo Möller, Birgit Muntau, Ellis Owusu-Dabo, Eileen G. Hoal, Stefan Niemann, Thorsten Thye, Gian D. van der Spuy, Elizabeth M. Streicher, Robin M. Warren, Haiko Schurz, Christian Meyer, Gerard Tromp, Paul D. van Helden, Craig J. Kinnear, Stephanie J. Muller
Publikováno v:
Genomics. 113(4)
Despite decades of research and advancements in diagnostics and treatment, tuberculosis remains a major public health concern. New computational methods are needed to interrogate the intersection of host- and bacterial genomes. Paired host genotype d
Autor:
Thorsten Thye, Gerard Tromp, Paul D. van Helden, Christian Meyer, Haiko Schurz, Stefan Niemann, Eileen G. Hoal, Elizabeth M. Streicher, Robin M. Warren, Stephanie J. Muller, Gian D. van der Spuy, Craig J. Kinnear, Ellis Owusu-Dabo, Marlo Möller
Despite decades of research and advancements in diagnostics and treatment, tuberculosis remains a major public health concern, particularly in low- and middle-income countries. New bioinformatics and computational methods are needed to interrogate th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::236d67128ac71a974ad7208fae3d121d
https://doi.org/10.1101/2020.07.27.20162925
https://doi.org/10.1101/2020.07.27.20162925
Autor:
Samantha L. Sampson, Namaunga Kasumu Chisompola, Elizabeth M. Streicher, Robin M. Warren, Chishala Miriam Kapambwe Muchemwa
Publikováno v:
BMC Infectious Diseases, Vol 20, Iss 1, Pp 1-16 (2020)
BMC Infectious Diseases
BMC Infectious Diseases
Background The burden of drug resistant tuberculosis in Africa is largely driven by the emergence and spread of multidrug resistant (MDR) and extensively drug resistant (XDR) Mycobacterium tuberculosis strains. MDR-TB is defined as resistance to ison
Autor:
Grant A. Hill-Cawthorne, Anzaan Dippenaar, Scott Burns, Tim H. Heupink, Keertan Dheda, Abdallah M. Abdallah, Matthias Merker, Margaretha de Vos, James E. Posey, Marisa Klopper, Arnab Pain, Jason Limberis, Stefan Niemann, Elizabeth M. Streicher, Robin M. Warren
Publikováno v:
BMC medicine
BMC Medicine
BMC Medicine, Vol 18, Iss 1, Pp 1-14 (2020)
BMC Medicine
BMC Medicine, Vol 18, Iss 1, Pp 1-14 (2020)
Background Atypical Beijing genotype Mycobacterium tuberculosis strains are widespread in South Africa and have acquired resistance to up to 13 drugs on multiple occasions. It is puzzling that these strains have retained fitness and transmissibility
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ba31509326b82bf148df38ae99fab9b
Autor:
David M, Engelthaler, Elizabeth M, Streicher, Erin J, Kelley, Christopher J, Allender, Kristin, Wiggins, Dulce, Jimenez, Darrin, Lemmer, Eric, Vittinghoff, Grant, Theron, Frederick A, Sirgel, Robin M, Warren, John Z, Metcalfe
Publikováno v:
Am J Respir Cell Mol Biol
Autor:
Wendy Stevens, Lesley Scott, Guido Groenen, Elizabeth M. Streicher, Elise De Vos, Robin M. Warren, Michael G. Whitfield, Vanessa Mathys, Frederick A. Sirgel, Annelies Van Rie
Publikováno v:
The journal of antimicrobial chemotherapy
Background: Use of the Xpert MTB/RIF assay has increased the number of people diagnosed with rifampicin-resistant tuberculosis (RR-TB), especially in South Africa where Xpert is now the initial diagnostic for individuals with TB symptoms. We hypothes
Autor:
Robin M. Warren, Elizabeth M. Streicher, Samantha L. Sampson, Mathias Tembo, Michael G. Whitfield, Sydney Mwanza, Namaunga K. Chisompola, Anzaan Dippenaar
Publikováno v:
Tuberculosis. 130:102122
Tuberculosis (TB) caused by Mycobacterium tuberculosis remains a major cause of death worldwide. Diverse genotypes have been demonstrated to drive the epidemiology of drug resistant (DR-) TB globally. Currently, there is limited knowledge on the geno
Autor:
Aliasgar Esmail, Robin M. Warren, Maia Lesosky, Ruth McNerney, Tawanda Gumbo, Julian te Riele, Taane G. Clark, Fathia Ben-Rached, Jason Limberis, Liezel Smith, Jody Phelan, Barbara Lazaro Mastrapa, Frederick A. Sirgel, Tania Dolby, John M. Simpson, Paul D. van Helden, Kevin P. Fennelly, Arnab Pain, Elize Pietersen, Elizabeth M. Streicher, Keertan Dheda, Abdallah M. Abdallah, Grant Theron
Publikováno v:
The Lancet Respiratory Medicine. 5:269-281
The emergence of programmatically incurable tuberculosis threatens to destabilise control efforts. The aim of this study was to collect prospective patient-level data to inform treatment and containment strategies.In a prospective cohort study, 273 S
Autor:
Elizabeth J. Ragan, Marinus Barnard, Paul D. van Helden, Annelies Van Rie, Wendy S. Stevens, Tania Dolby, John Simpson, Lesley Scott, Karen R. Jacobson, Mary B. Kleinman, Elizabeth M. Streicher, Ofer Shapira, Robin M. Warren, Laura F. White
Publikováno v:
Clinical infectious diseases
Background. Xpert MTB/RIF (Xpert) detects rifampicin-resistant tuberculosis (RR-tuberculosis), enabling physicians to rapidly initiate a World Health Organization-recommended 5-drug regimen while awaiting second-line drug-susceptibility test (DST) re
Autor:
Richard Hafner, Robin M. Warren, Bavesh D. Kana, Kennedy Otwombe, Germar Beukes, Neil A. Martinson, Elizabeth M. Streicher, Bhavna G. Gordhan, Gavin J. Churchyard, Melissa Chengalroyen
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 194:1532-1540
Rationale: Recent studies suggest that baseline tuberculous sputum comprises a mixture of routinely culturable and differentially culturable tubercle bacteria (DCTB). The latter seems to be drug tolerant and dependent on resuscitation-promoting facto