Zobrazeno 31 - 40
of 89
pro vyhledávání: '"Ebbe Boedtkjer"'
Publikováno v:
Physiological Reports, Vol 7, Iss 8, Pp n/a-n/a (2019)
Møller, A L, Hjortdal, V E, Bødtkjer, D B & Boedtkjer, E 2019, ' Acidosis inhibits rhythmic contractions of human thoracic ducts ', Physiological Reports, vol. 7, no. 8, e14074 . https://doi.org/10.14814/phy2.14074
Physiological Reports
Møller, A L, Hjortdal, V E, Bødtkjer, D B & Boedtkjer, E 2019, ' Acidosis inhibits rhythmic contractions of human thoracic ducts ', Physiological Reports, vol. 7, no. 8, e14074 . https://doi.org/10.14814/phy2.14074
Physiological Reports
Lymph vessels counteract edema by transporting interstitial fluid from peripheral tissues to the large veins and serve as conduits for immune cells, cancer cells, and pathogens. Because edema during inflammation and malignancies is frequently associa
Autor:
Ebbe, Boedtkjer
Publikováno v:
Cancer metastasis reviews. 38(1-2)
Cell metabolism increases during carcinogenesis. Yet, intracellular pH in solid cancer tissue is typically maintained equal to or above that of normal tissue. This is achieved through accelerated cellular acid extrusion that compensates for the enhan
Publikováno v:
Voss, N C S, Kold-Petersen, H H & Boedtkjer, E 2019, ' Enhanced nitric oxide signaling amplifies vasorelaxation of human colon cancer feed arteries ', American Journal of Physiology: Heart and Circulatory Physiology, vol. 316, no. 1, pp. H245-H254 . https://doi.org/10.1152/ajpheart.00368.2018
Inadequate perfusion of solid cancer tissue results in low local nutrient and oxygen levels and accumulation of acidic waste products. Previous investigations have focused primarily on tumor blood vessel architecture, and we lack information concerni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4665622b514fc6642a40631c6b60c6f8
https://pure.au.dk/portal/da/publications/enhanced-nitric-oxide-signaling-amplifies-vasorelaxation-of-human-colon-cancer-feed-arteries(fce94c12-b044-4f3a-8a43-2c60600d6199).html
https://pure.au.dk/portal/da/publications/enhanced-nitric-oxide-signaling-amplifies-vasorelaxation-of-human-colon-cancer-feed-arteries(fce94c12-b044-4f3a-8a43-2c60600d6199).html
Autor:
Henrik Kold-Petersen, Ninna C. S. Voss, Casper Homilius, Ebbe Boedtkjer, Mikkel B. Henningsen
Publikováno v:
Voss, N C S, Kold-Petersen, H H, Henningsen, M B, Homilius, C & Boedtkjer, E 2019, ' Upregulated Na + /H +-exchange protects human colon cancer tissue against intracellular acidification ', BioMed Research International, vol. 2019, 3702783 . https://doi.org/10.1155/2019/3702783
BioMed Research International
BioMed Research International, Vol 2019 (2019)
BioMed Research International
BioMed Research International, Vol 2019 (2019)
Increased metabolism accelerates local acid production in cancer tissue. The mechanisms eliminating acidic waste products from human colon cancer tissue represent promising therapeutic targets for pharmacological manipulation in order to improve prog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::100bf714c00d6aa3a98379d7784224cf
https://pure.au.dk/portal/da/publications/upregulated-nahexchange-protects-human-colon-cancer-tissue-against-intracellular-acidification(08df03a6-f0bc-4f85-9e91-5d4daf27a06f).html
https://pure.au.dk/portal/da/publications/upregulated-nahexchange-protects-human-colon-cancer-tissue-against-intracellular-acidification(08df03a6-f0bc-4f85-9e91-5d4daf27a06f).html
Autor:
Paulus Wohlfart, Han Moshage, Lothar Schilling, Rudolf Schubert, Nina Weinzierl, Ebbe Boedtkjer, Natalia Lapina, Youhai Li, Lisbeth Bonde
Publikováno v:
Li, Y, Lapina, N, Weinzierl, N, Bonde, L, Boedtkjer, E, Schubert, R, Moshage, H, Wohlfahrt, P & Schilling, L 2018, ' A novel method to isolate retinal and brain microvessels from individual rats: microscopic and molecular biological characterization and application in hyperglycemic animals ', Vascular Pharmacology, vol. 110, pp. 24-30 .
Vascular pharmacology, 110, 24-30. ELSEVIER SCIENCE INC
Aarhus University
Vascular pharmacology, 110, 24-30. ELSEVIER SCIENCE INC
Aarhus University
Alterations in the retinal microvessel (RMV) compartment occurring in systemic disease states such as diabetes may eventually contribute to blindness. To specifically address the pathophysiological role of the microvasculature we developed a new meth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42eda79869ea1d4a541aa165ebaa75cc
https://pure.au.dk/portal/da/publications/a-novel-method-to-isolate-retinal-and-brain-microvessels-from-individual-rats-microscopic-and-molecular-biological-characterization-and-application-in-hyperglycemic-animals(6c778721-cf3d-42d9-a87a-531a00872c05).html
https://pure.au.dk/portal/da/publications/a-novel-method-to-isolate-retinal-and-brain-microvessels-from-individual-rats-microscopic-and-molecular-biological-characterization-and-application-in-hyperglycemic-animals(6c778721-cf3d-42d9-a87a-531a00872c05).html
Autor:
Nicolai Jessen, Ebbe Boedtkjer, Stine F. Pedersen, Trine V Axelsen, Soojung Lee, Pernille Vahl
Publikováno v:
Lee, S, Axelsen, T V, Jessen, N, Pedersen, S F, Vahl, P & Boedtkjer, E 2018, ' Na +,HCO 3 –-cotransporter NBCn1 (Slc4a7) accelerates ErbB2-induced breast cancer development and tumor growth in mice ', Oncogene, vol. 37, no. 41, pp. 5569-5584 . https://doi.org/10.1038/s41388-018-0353-6
Metabolic acid production challenges cellular pH homeostasis in solid cancer tissue, and mechanisms of net acid extrusion represent promising new targets for breast cancer therapy. Here, we used genetically engineered mice to investigate the contribu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7654b11d4dea51650c8a3abd257d60ad
https://pure.au.dk/portal/da/publications/na-hco3cotransporter-nbcn1-slc4a7-accelerates-erbb2induced-breast-cancer-development-and-tumor-growth-in-mice(b1077be5-30cd-4d20-acfa-cbf2016586c9).html
https://pure.au.dk/portal/da/publications/na-hco3cotransporter-nbcn1-slc4a7-accelerates-erbb2induced-breast-cancer-development-and-tumor-growth-in-mice(b1077be5-30cd-4d20-acfa-cbf2016586c9).html
Autor:
Ebbe Boedtkjer, Ulf Simonsen
Publikováno v:
Aarhus University
Simonsen, U & Boedtkjer, E 2016, ' New roles of factors from perivascular tissue in regulation of vascular tone ', Acta Physiologica, vol. 216, no. 2, pp. 159-162 .
Simonsen, U & Boedtkjer, E 2016, ' New roles of factors from perivascular tissue in regulation of vascular tone ', Acta Physiologica, vol. 216, no. 2, pp. 159-162 .
Publikováno v:
The Journal of Physiology. 593:4747-4764
Interactions between perivascular tissue (PVT) and the vascular wall modify artery tone and contribute to local blood flow regulation. Using isometric myography, fluorescence microscopy, membrane potential recordings and phosphospecific immunoblottin
Autor:
Soojung, Lee, Trine V, Axelsen, Nicolai, Jessen, Stine F, Pedersen, Pernille, Vahl, Ebbe, Boedtkjer
Publikováno v:
Oncogene. 37(41)
Metabolic acid production challenges cellular pH homeostasis in solid cancer tissue, and mechanisms of net acid extrusion represent promising new targets for breast cancer therapy. Here, we used genetically engineered mice to investigate the contribu
Autor:
Ebbe Boedtkjer
Publikováno v:
Boedtkjer, E 2018, ' Acid-base regulation and sensing: accelerators and brakes in metabolic regulation of cerebrovascular tone ', Journal of Cerebral Blood Flow and Metabolism, vol. 38, no. 4, pp. 588-602 . https://doi.org/10.1177/0271678X17733868
Metabolic regulation of cerebrovascular tone directs blood flow to areas of increased neuronal activity and during disease states partially compensates for insufficient perfusion by enhancing blood flow in collateral blood vessels. Acid–base distur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e42c8e9f695245e0c3731c963836af56
https://europepmc.org/articles/PMC5888856/
https://europepmc.org/articles/PMC5888856/