Zobrazeno 51 - 60
of 76
pro vyhledávání: '"Doug-Young Ryu"'
Autor:
Joon-Hyoung Cho, Doug-Young Ryu, Sang-Hee Jeong, Hwan-Goo Kang, Hyun-Mi Pyo, Hyun-Ok Ku, Seong-Wan Son, So-Mi Yun
Publikováno v:
Toxicology letters. 190(2)
It is often difficult to discriminate between chemically induced skin irritation and sensitization due to their similar clinical, pathological, and immunological responses. More information than that currently available from local lymph node assays (
Publikováno v:
Cancer Letters. 143:245-247
Double transgenic mice bearing fusion genes consisting of mouse albumin enhancer/promoter-mouse c-myc cDNA and mouse metallothionein1 promoter-human TGFalpha cDNA were generated to investigate the interaction of these genes in hepatic oncogenesis and
Autor:
Hyun-Ok Ku, Doug Young Ryu, Kwang-jick Lee, Hwan-Goo Kang, Hyun-Mi Pyo, Seong-Wan Son, Sang-Hee Jeong, Hye-Ryeong Kim, Joon-Hyoung Cho
Publikováno v:
Toxicology. 250(2-3)
The murine local lymph node assay (LLNA) has been extensively utilized to evaluate sensitizing chemicals. However, there have been some concerns that its use to discriminate between classes of chemicals is minimal. It is thus desirable to identify be
Autor:
Mingai Huang, Jae Chul Choi, Doug-Young Ryu, Na-Young Kim, Jae Yeol Kim, Jong Wook Shin, Soo Im Chang, Jung-Duck Park, Seong-Jin Choi, Byung-Sun Choi, Byoung Whui Choi, Ruth Im, In Won Park, Changbo Park
Publikováno v:
Toxicological Research
The G184C and G134A single nucleotide polymorphisms (SNPs) of the CYP1A1 gene result in Ala62Pro and Gly45Asp substitutions, respectively. Here, we tested whether these SNPs are associated with an alteration in lung cancer incidence. We examined 80 K
Publikováno v:
Biologicalpharmaceutical bulletin. 28(11)
Glucose transporter 2 (GLUT2) is tissue-specifically expressed in liver and kidney, and reduced in neoplastic hepatic lesions and in most hepatoma cell lines. Here we examined the involvement of epigenetic modifications in the regulation of GLUT2. Fo
Autor:
Hee Jeong YU, Seung Heon LEE, Seungwoo LEE, Yu Jung CHOI, Dayoung OH, Ki-Hoan NAM, YoungMin YUN, Doug-Young RYU
Publikováno v:
Journal of Veterinary Medical Science; Aug2017, Vol. 79 Issue 8, p1327-1334, 8p
Autor:
Doug-Young Ryu, Bohwan Jin
Publikováno v:
Journal of biochemical and molecular toxicology. 18(3)
Cytochrome P450 1A2 (CYP1A2) is constitutively expressed in the mouse liver, but the constitutive expression progressively declines to an undetectable level in isolated hepatocytes. In this study, CYP1A2 was induced in hepatocytes exposed to the hist
Autor:
Jung-Duck Park, Curtis D. Klaassen, Sung-Ja Lee, Duk Woong Park, Doug-Young Ryu, Byung-Sun Choi
Publikováno v:
Toxicology letters. 152(1)
The intestinal absorption of cadmium (Cd) is influenced by body iron (Fe) status in laboratory animals and humans. In this study we investigated the role of the apical Fe transporter divalent metal transporter 1 (DMT1) and the basolateral Fe exporter
Publikováno v:
Toxicology letters. 152(1)
Cytochrome P450 1A2 (CYP1A2) is a xenobiotic metabolizing enzyme that is tissue-specifically regulated in the mammalian liver by arylhydrocarbon receptor (AhR)-dependent and -independent pathways. In this study, CpG methylation of the CYP1A2 promoter
Publikováno v:
Toxicology in vitro : an international journal published in association with BIBRA. 18(5)
Differential expression of various genes was observed in the Hepa1c1c7 cell line following exposure to the DNA methylation inhibitor 5-aza-2′-deoxycytidine (AzaC) and to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). AzaC treatment generally affected