Zobrazeno 31 - 40
of 117
pro vyhledávání: '"Dawang Zhou"'
Autor:
Zhang Jingfang, Yunzhan Li, Zhenzhen Fan, Zhuang Zhongji, Li Li, Ting Zhang, Dawang Zhou, Sun Xihuan, Xianming Deng, Liu Yan, Fu Gui, Deng Zhou, Jie Jiang, Su-Jie Zhu, Huang Xiaoxing, Yue Lu, Siyang Song, Jianming Zhang, Xuehui Hong, Zhang Baoding, Qiao Wu, Lanfen Chen, Wei Huang, Xin Huang, Cai-Hong Yun, Qiyuan Li, Liang Chen, Lei Gao, Zheng Wang
Publikováno v:
EMBO Molecular Medicine, Vol 14, Iss 1, Pp n/a-n/a (2022)
EMBO Molecular Medicine
EMBO Molecular Medicine
More than 60% of nonsmall cell lung cancer (NSCLC) patients show a positive response to the first ALK inhibitor, crizotinib, which has been used as the standard treatment for newly diagnosed patients with ALK rearrangement. However, most patients ine
Autor:
Chen-Song Zhang, Bingchang Zhang, Mengqi Li, Xiaoyan Wei, Kai Gong, Zhiyong Li, Xiangyang Yao, Jianfeng Wu, Cixiong Zhang, Mingxia Zhu, Lei Zhang, Xiufeng Sun, Yi-Hong Zhan, Zhengye Jiang, Wenpeng Zhao, Wei Zhong, Xinguo Zhuang, Dawang Zhou, Hai-Long Piao, Sheng-Cai Lin, Zhanxiang Wang
Publikováno v:
Science China. Life sciences. 65(10)
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is characterized by a strong production of inflammatory cytokines such as TNF and IL-6, which underlie the severity of the disease. However,
Publikováno v:
Small methods. 5(3)
Autor:
Dawang Zhou, Shihao Zhang
Publikováno v:
Current Opinion in Cell Biology. 61:64-71
Liver cancer, hepatocellular carcinoma (HCC) in particular, is one of the deadliest cancers worldwide. Although the etiologies for liver oncogenesis are relatively well defined, the exact mechanisms leading to cancer development remain elusive. The H
Autor:
Sixian Qi, Yuwen Zhu, Xincheng Liu, Pengyue Li, Yebin Wang, Yan Zeng, Aijuan Yu, Yu Wang, Zhao Sha, Zhenxing Zhong, Rui Zhu, Haixin Yuan, Dan Ye, Shenglin Huang, Chen Ling, Yanhui Xu, Dawang Zhou, Lei Zhang, Fa-Xing Yu
Publikováno v:
Molecular cell. 82(10)
YAP and TAZ (YAP/TAZ), two major effectors of the Hippo signaling pathway, are frequently activated in human cancers. The activity of YAP/TAZ is strictly repressed upon phosphorylation by LATS1/2 tumor suppressors. However, it is unclear how LATS1/2
Autor:
Jinjia Zhang, Yiran Shi, Jing Geng, Weihong Yuan, Ping Wang, Hao Zhao, Dawang Zhou, Bingying Yang, Xianming Deng, Funiu Qin, Lixin Hong, Yujie Sun, Junhong Li, Lanfen Chen, Congying Wu, Changchuan Xie
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Nature Communications
Nature Communications
TLR4 signaling plays key roles in the innate immune response to microbial infection. Innate immune cells encounter different mechanical cues in both health and disease to adapt their behaviors. However, the impact of mechanical sensing signals on TLR
Publikováno v:
Ann Transl Med
Background The expression profile of lncRNAs in coronary artery disease (CAD) patients has not yet been fully explored. Therefore, the current study aimed to investigate lncRNA-based prognostic biomarkers for CAD. Methods The expression profiles of l
Autor:
Fei Chen, Dawang Zhou, Jiancheng Ding, Wen Liu, Aicun Li, Lei Zhang, Han You, Zhe Meng, Zhicheng Gong, Ronggui Hu, Yuanpei Li, Jialiang Huang, Qing Li, Jing Ye
Publikováno v:
Advanced Science
Advanced Science, Vol 8, Iss 15, Pp n/a-n/a (2021)
Advanced Science, Vol 8, Iss 15, Pp n/a-n/a (2021)
Genomic amplification of OTUD7B is frequently found across human cancers. But its role in tumorigenesis is poorly understood. Lysine‐specific demethylase 1 (LSD1) is known to execute epigenetic regulation by forming corepressor complex with CoREST/
Autor:
Jing Wang, Qiyao Chai, Yanzhao Zhong, Lingqiang Zhang, Yong Zhang, Wenzhu Dong, Cui Hua Liu, George F. Gao, Pupu Ge, Yu Pang, Dawang Zhou, Wei Li, Xudong Wang, Bingxi Li, Zhe Lu, Lihua Qiang
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Nature Communications
Nature Communications
Ubiquitin-mediated xenophagy, a type of selective autophagy, plays crucial roles in host defense against intracellular pathogens including Mycobacterium tuberculosis (Mtb). However, the exact mechanism by which host ubiquitin targets invaded microbes
Autor:
Kang Cheng, Dawang Zhou, Yuan-li Ai, Hang-zi Chen, Ru-yue Sun, Jiahuai Han, Jia-yuan Zhang, Bo Zhou, Xian-shuo Liu, Qiao Wu
Publikováno v:
Cell Research
Iron has been shown to trigger oxidative stress by elevating reactive oxygen species (ROS) and to participate in different modes of cell death, such as ferroptosis, apoptosis and necroptosis. However, whether iron-elevated ROS is also linked to pyrop