Zobrazeno 61 - 70
of 80
pro vyhledávání: '"Davide Trotti"'
Autor:
W R Harvey, Matthias A. Hediger, V. F. Sacchi, Michela Castagna, Davide Trotti, Chairat Shayakul
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 95(9)
Active solute uptake in bacteria, fungi, plants, and animals is known to be mediated by cotransporters that are driven by Na + or H + gradients. The present work extends the Na + and H + dogma by including the H + and K + paradigm. Lepidopteran insec
Publikováno v:
The European journal of neuroscience. 9(10)
Control of extrasynaptic glutamate concentration in the central nervous system is an important determinant of neurotransmission and excitotoxicity. Mechanisms that modulate glutamate transporter function are therefore critical factors in these proces
Autor:
Matthias A. Hediger, Michael F. Romero, Walter F. Boron, Davide Trotti, Angela Steel, Stephan Nussberger
Publikováno v:
The Journal of biological chemistry. 272(12)
Ion-coupled solute transporters exhibit pre-steady-tate currents that resemble those of voltage-dependent ion channels. These currents were assumed to be mostly due to binding and dissociation of the coupling ion near the extracellular transporter su
Autor:
Niels C. Danbolt, Kyrre Ullensvang, Giorgio Racagni, Barbara Lodi Rizzini, Andrea Volterra, Davide Trotti, Paola Bezzi
Publikováno v:
Scopus-Elsevier
We studied the early and late effects of L-trans-pyrrolidine-2,4-dicarboxylate (PDC), a competitive inhibitor of glutamate uptake with low affinity for glutamate receptors, in co-cultures of rat cortical neurons and glia expressing spontaneous excita
Autor:
Daniela Rossi, Andrea Volterra, Barbara Lodi Rizzini, Paola Bezzi, Davide Trotti, Giorgio Racagni, Niels C. Danbolt
Publikováno v:
Neurodegenerative Diseases ISBN: 9781489902115
Glutamate uptake is essential to maintain resting extracellular glutamate ([Glu]0) ≤ 1 μM, a concentration not producing significant activation of excitatory aminoacid (EAA) receptors’. Thereby, sharp synaptic signalling takes place upon glutama
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b1b2d174d295b3ad12cdae8bb1b88eb9
https://doi.org/10.1007/978-1-4899-0209-2_5
https://doi.org/10.1007/978-1-4899-0209-2_5
Publikováno v:
Neuroscience letters. 183(3)
While studying the enzymatic processing of arachidonic acid (AA) to eicosanoids in homogenates of hippocampal astrocytes, we observed that all the HPLC peaks corresponding to AA metabolites displayed significantly different levels depending on the pr
Publikováno v:
Scopus-Elsevier
Publikováno v:
European Neuropsychopharmacology. 3:182-183
Our data show that arachidonic acid and oxygen free radicals converge in potently inhibiting high-affinity glutamate uptake with two distinct molecular mechanisms. Since the levels of free fatty acids and reactive oxygen species dramatically increase
Autor:
Emily Foran, Davide Trotti
Publikováno v:
Antioxidants & Redox Signaling; Jul2009, Vol. 11 Issue 7, p1587-1602, 16p
Publikováno v:
European Neuropsychopharmacology. 5:224