Zobrazeno 201 - 208
of 208
pro vyhledávání: '"David L. Huso"'
Publikováno v:
EJNMMI Research
Background The goal of the study is to investigate 18F-fluorodeoxyglucose positron emission tomography (18F-FDG-PET)’s ability to delineate the viable portion of a tumor in an animal model using cross-sectional histology as the validation standard.
Autor:
Jiuxiang Zhu, Shibin Zhou, Bert Vogelstein, Oleg Schmidt-Kittler, Jian Yang, Christoph Lengauer, William P.D. Hendricks, David L. Huso, Guosheng Liu, Sandra B. Gabelli, Kenneth W. Kinzler
Publikováno v:
Scopus-Elsevier
Oncotarget
Oncotarget
Previous genetic analyses have suggested that mutations of the genes encoding PI3Kα facilitate invasion and metastasis but have less effect on primary tumor growth. These findings have major implications for therapeutics but have not been factored i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a71c3dd46eebc1c13aca2a0184899b49
http://www.scopus.com/inward/record.url?eid=2-s2.0-79952087950&partnerID=MN8TOARS
http://www.scopus.com/inward/record.url?eid=2-s2.0-79952087950&partnerID=MN8TOARS
Publikováno v:
BMC Cancer
Colorectal cancer (CRC) is the second leading cause of death from cancer in the United States. Colorectal cancers have a prolonged latency following initiation that may span decades providing ample time for implementing a chemoprevention strategy tha
Autor:
Sandeep N Shah, Leslie Cope, Weijie Poh, Amy Belton, Sujayita Roy, C Conover Talbot, Saraswati Sukumar, David L Huso, Linda M S Resar
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e63419 (2013)
Emerging evidence suggests that tumor cells metastasize by co-opting stem cell transcriptional networks, although the molecular underpinnings of this process are poorly understood. Here, we show for the first time that the high mobility group A1 (HMG
Externí odkaz:
https://doaj.org/article/2652faf1f1464808afb5edb5567c23ae
Autor:
Amy Belton, Alexander Gabrovsky, Young Kyung Bae, Ray Reeves, Christine Iacobuzio-Donahue, David L Huso, Linda M S Resar
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e30034 (2012)
BackgroundAlthough metastatic colon cancer is a leading cause of cancer death worldwide, the molecular mechanisms that enable colon cancer cells to metastasize remain unclear. Emerging evidence suggests that metastatic cells develop by usurping trans
Externí odkaz:
https://doaj.org/article/cf7f5c65cba94c97b365e6fa24a397bf
Autor:
Sandeep N Shah, Candace Kerr, Leslie Cope, Elias Zambidis, Cyndi Liu, Joelle Hillion, Amy Belton, David L Huso, Linda M S Resar
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e48533 (2012)
BackgroundAlthough recent studies have identified genes expressed in human embryonic stem cells (hESCs) that induce pluripotency, the molecular underpinnings of normal stem cell function remain poorly understood. The high mobility group A1 (HMGA1) ge
Externí odkaz:
https://doaj.org/article/bf1d8137a917472cac9e7e1d97cda020
Autor:
Eva Andres-Mateos, Rebeca Mejias, Arshia Soleimani, Brian M Lin, Tyesha N Burks, Ruth Marx, Benjamin Lin, Richard C Zellars, Yonggang Zhang, David L Huso, Tom G Marr, Leslie A Leinwand, Dana K Merriman, Ronald D Cohn
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e48884 (2012)
Skeletal muscle atrophy can occur as a consequence of immobilization and/or starvation in the majority of vertebrates studied. In contrast, hibernating mammals are protected against the loss of muscle mass despite long periods of inactivity and lack
Externí odkaz:
https://doaj.org/article/ef4465b7d4724246ad44a972e47f3a2b
Autor:
Miguel A Garcia-Gonzalez, Patricia Outeda, Qin Zhou, Fang Zhou, Luis F Menezes, Feng Qian, David L Huso, Gregory G Germino, Klaus B Piontek, Terry Watnick
Publikováno v:
PLoS ONE, Vol 5, Iss 9 (2010)
Autosomal dominant polycystic kidney disease (ADPKD) is a common cause of inherited renal failure that results from mutations in PKD1 and PKD2. The disorder is characterized by focal cyst formation that involves somatic mutation of the wild type alle
Externí odkaz:
https://doaj.org/article/5625a3686f1e4e759055e408742f7e50