Zobrazeno 91 - 100
of 160
pro vyhledávání: '"David G. Hoel"'
Autor:
David G. Hoel
Publikováno v:
Radiation Research. 136:137
Publikováno v:
Radiation Research. 130:249
Deaths in the RERF Life Span Study (LSS) sample have been determined for the years 1950-1985 and an analysis of cancer mortality with the revised DS86 doses has been described separately. In this report, we examine the relationship to dose of deaths
Publikováno v:
Toxicology and Applied Pharmacology. 55:154-161
A general scheme is proposed which relates the carcinogenic responses to the amount of DNA-carcinogen adduct formed instead of applied dose. Based on the present understanding of the mechanism of carcinogenesis, we believe this to be a more rational
Autor:
David G. Hoel
Publikováno v:
Environmental Health Perspectives
Risk estimation in radiation carcinogenesis depends primarily on epidemiological data and hazard rate models. The A-bomb survivors follow-up provides information on the complexity of this process. Several hazard rate models are briefly discussed and
Autor:
David G. Hoel, Gerald R. Chase
Publikováno v:
Biometrika. 62:329-334
SUMMARY The effect of small errors of dilution is shown to be sizeable when serial dilutions are required to estimate particle concentrations. Optimal dilution designs are given. The error effect and optimal design are also investigated for ratios of
Publikováno v:
Biometrika. 62:195-200
We examine results produced by a new likelihood stopping rule for terminating clinical trials, designed to choose the better of two competing dichotomous treatments, or to decide that they are equal. A method for adaptive assignment is also discussed
Autor:
George H. Weiss, David G. Hoel
Publikováno v:
Transportation Research. 11:39-44
Several studies indicate that rural traffic flow can most accurately be modelled in terms of travelling queues of vehicles as proposed by Miller (1963). The second order statistical properties (variance, autocorrelation function, and spectral density
Autor:
David G. Hoel, Walter W. Piegorsch
Publikováno v:
Mutation Research/Reviews in Genetic Toxicology. 196:161-175
Salmonella mutagenic and rodent carcinogenic potencies are calculated for 112 compounds recently studied by the U.S. National Toxicology Program. 28 of the 112 compounds are seen to exhibit simultaneous non-zero mutagenic and carcinogenic potencies.
Autor:
Takashi Yanagawa, David G. Hoel
Publikováno v:
Environmental Health Perspectives
Statistical methods for the use of historical control data in testing for a trend in proportions in carcinogenicity rodent bioassays are reviewed. Asymptotic properties of the Hoel-Yanagawa exact conditional tests are developed and compared with the
Publikováno v:
Toxicological Sciences. 5:79-86