Zobrazeno 91 - 100
of 10 222 884
pro vyhledávání: '"David A"'
Autor:
Jamie L. Adams, Tairmae Kangarloo, Yishu Gong, Vahe Khachadourian, Brian Tracey, Dmitri Volfson, Robert D. Latzman, Joshua Cosman, Jeremy Edgerton, David Anderson, Allen Best, Melissa A. Kostrzebski, Peggy Auinger, Peter Wilmot, Yvonne Pohlson, Stella Jensen-Roberts, Martijn L. T. M. Müller, Diane Stephenson, E. Ray Dorsey, the Parkinson Study Group Watch-PD Study Investigators and Collaborators
Publikováno v:
npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-11 (2024)
Abstract Digital measures may provide objective, sensitive, real-world measures of disease progression in Parkinson’s disease (PD). However, multicenter longitudinal assessments of such measures are few. We recently demonstrated that baseline asses
Externí odkaz:
https://doaj.org/article/7b304f263c954a19b734d9277ee6190c
Autor:
Jenny Yang, Lei Clifton, Nguyen Thanh Dung, Nguyen Thanh Phong, Lam Minh Yen, Doan Bui Xuan Thy, Andrew A. S. Soltan, Louise Thwaites, David A. Clifton
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Collaborative efforts in artificial intelligence (AI) are increasingly common between high-income countries (HICs) and low- to middle-income countries (LMICs). Given the resource limitations often encountered by LMICs, collaboration becomes
Externí odkaz:
https://doaj.org/article/a88db8c825944c868781efc98703caa4
Autor:
Sebastijan Hobor, Maise Al Bakir, Crispin T. Hiley, Marcin Skrzypski, Alexander M. Frankell, Bjorn Bakker, Thomas B. K. Watkins, Aleksandra Markovets, Jonathan R. Dry, Andrew P. Brown, Jasper van der Aart, Hilda van den Bos, Diana Spierings, Dahmane Oukrif, Marco Novelli, Turja Chakrabarti, Adam H. Rabinowitz, Laila Ait Hassou, Saskia Litière, D. Lucas Kerr, Lisa Tan, Gavin Kelly, David A. Moore, Matthew J. Renshaw, Subramanian Venkatesan, William Hill, Ariana Huebner, Carlos Martínez-Ruiz, James R. M. Black, Wei Wu, Mihaela Angelova, Nicholas McGranahan, Julian Downward, Juliann Chmielecki, Carl Barrett, Kevin Litchfield, Su Kit Chew, Collin M. Blakely, Elza C. de Bruin, Floris Foijer, Karen H. Vousden, Trever G. Bivona, TRACERx consortium, Robert E. Hynds, Nnennaya Kanu, Simone Zaccaria, Eva Grönroos, Charles Swanton
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract The phenomenon of mixed/heterogenous treatment responses to cancer therapies within an individual patient presents a challenging clinical scenario. Furthermore, the molecular basis of mixed intra-patient tumor responses remains unclear. Here
Externí odkaz:
https://doaj.org/article/a58c4b29e1d8491b8078212067633916
Autor:
Alastair Magness, Emma Colliver, Katey S. S. Enfield, Claudia Lee, Masako Shimato, Emer Daly, David A. Moore, Monica Sivakumar, Karishma Valand, Dina Levi, Crispin T. Hiley, Philip S. Hobson, Febe van Maldegem, James L. Reading, Sergio A. Quezada, Julian Downward, Erik Sahai, Charles Swanton, Mihaela Angelova
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract The growing scale and dimensionality of multiplexed imaging require reproducible and comprehensive yet user-friendly computational pipelines. TRACERx-PHLEX performs deep learning-based cell segmentation (deep-imcyto), automated cell-type ann
Externí odkaz:
https://doaj.org/article/f61b4b8bd2f54cbd9679706490019396
Autor:
Adalberto Claudio Quiros, Nicolas Coudray, Anna Yeaton, Xinyu Yang, Bojing Liu, Hortense Le, Luis Chiriboga, Afreen Karimkhan, Navneet Narula, David A. Moore, Christopher Y. Park, Harvey Pass, Andre L. Moreira, John Le Quesne, Aristotelis Tsirigos, Ke Yuan
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-24 (2024)
Abstract Cancer diagnosis and management depend upon the extraction of complex information from microscopy images by pathologists, which requires time-consuming expert interpretation prone to human bias. Supervised deep learning approaches have prove
Externí odkaz:
https://doaj.org/article/24019f1068da441492cffc896558e017
Autor:
Kärt Paiste, David A. Fike, Karen Bakakas Mayika, Mathieu Moussavou, Aivo Lepland, Anthony R. Prave, Tomohiko Sato, Yuichiro Ueno, Yusuke Sawaki, Jocelyn A. Richardson, Robert S. Wood, Clive Jones, Samuel M. Webb, Kalle Kirsimäe
Publikováno v:
Communications Earth & Environment, Vol 5, Iss 1, Pp 1-14 (2024)
Abstract Bulk-rock sulfur isotope data from pyrite in the ~2.1 billion-year sedimentary rocks of the Francevillian Basin, Gabon, have underpinned ideas about initial oxygenation of Earth’s surface environments and eukaryote evolution. Here, we show
Externí odkaz:
https://doaj.org/article/bbfb7ade15a842c1bc3cbe85564405b6
Autor:
Miguel Antonio Sánchez-Cárdenas, Camila Andrea Navarro Tibaquirá, Nidia Mantilla-Manosalva, David Andrade Fonseca, Alexandra Marin Morales, Martha Ximena León Delgado
Publikováno v:
BMC Palliative Care, Vol 23, Iss 1, Pp 1-7 (2024)
Abstract Background The number of people suffering from chronic diseases requiring palliative care (PC) is increasing rapidly. Therefore, PC teaching in undergraduate health science programs is necessary to improve primary PC based on international r
Externí odkaz:
https://doaj.org/article/b6238443565f43e3bce8faba44b231d1
Publikováno v:
Journal of Eating Disorders, Vol 12, Iss 1, Pp 1-12 (2024)
Abstract Background Weight suppression has been defined as diet-induced weight loss, traditionally operationalized as the difference between one’s highest and current weight. This concept has been studied in the context of eating disorders, but its
Externí odkaz:
https://doaj.org/article/dc6c7b335fd34cdea249b238cf27b15d
Publikováno v:
BMC Medical Informatics and Decision Making, Vol 24, Iss 1, Pp 1-21 (2024)
Abstract Background The increased application of Internet of Things (IoT) in healthcare, has fueled concerns regarding the security and privacy of patient data. Lightweight Cryptography (LWC) algorithms can be seen as a potential solution to address
Externí odkaz:
https://doaj.org/article/eb86c0fb6fae4169899fd3b8240c044f
Autor:
Stanley Cohen, Jean S. Beebe, Vishala Chindalore, Shunjie Guan, Mina Hassan-Zahraee, Madhurima Saxena, Li Xi, Craig Hyde, Sarita Koride, Robert Levin, Shannon Lubaczewski, Mikhail Salganik, Abigail Sloan, Erin Stevens, Elena Peeva, Michael S. Vincent, David A. Martin, Myron Chu
Publikováno v:
Arthritis Research & Therapy, Vol 26, Iss 1, Pp 1-18 (2024)
Abstract Background The objective of this study was to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of PF‑06835375, a potent selective afucosyl immunoglobulin G1 antibody targeting C-X-C chemokine receptor type 5 (CXCR5
Externí odkaz:
https://doaj.org/article/de4e6e08230342d8a8ccd262c81c4143