Zobrazeno 31 - 40
of 147
pro vyhledávání: '"Daniel R Ambruso"'
Publikováno v:
Blood. 105:2266-2273
Transfusion-related acute lung injury (TRALI) is a life-threatening adverse effect of transfusion that is occurring at increasing incidence in the United States and that, in the past 2 reporting years, has been the leading cause of transfusion-relate
Autor:
Zahra Mehdizadehkashi, T. Masuno, Kelly M. England, Christopher C. Silliman, F. J. Kim, Marguerite R. Kelher, Ernest E. Moore, R. B. Covin, Daniel R. Ambruso, Lynn K. Boshkov
Publikováno v:
Transfusion Medicine. 14:375-383
Transfusion of autologous blood is associated with fewer complications, although all untoward events of transfusion may not be negated with this strategy. We report a case of acute pulmonary insufficiency and hypotension following transfusion of auto
Autor:
Daniel R. Ambruso, Amy N. Abell, Aimee deCathelineau, Gary L. Johnson, David W. H. Riches, Scott A. Weed
Publikováno v:
Journal of Cell Science. 117:243-255
Rac2 is a Rho GTPase that is expressed in cells of hematopoietic origin, including neutrophils and macrophages. We recently described an immunodeficient patient with severe, recurrent bacterial infections that had a point mutation in one allele of th
Autor:
Christopher C. Silliman, Marguerite R. Kelher, Gail Thurman, Steven M. Anderson, David J. Elzi, Andrew J. Paterson, Daniel R. Ambruso
Publikováno v:
Cell Calcium. 34:445-455
Chemoattractant priming and activation of PMNs results in changes in cytosolic Ca 2+ concentration, tyrosine kinase activity, and gene expression. We hypothesize that the initial signaling for the activation of a 105 kDa protein (Rel-1) requires Ca 2
Publikováno v:
Transfusion. 52:1155-1157
We read with interest the recent publication of Vlaar and colleagues,1 which detailed the accumulation of bio-active lipids during the storage of blood products and their findings that these lipids are not cell but plasma and temperature dependent. I
Autor:
Thomas L. Leto, Agnieszka Korzeniowska, lker Esroy, Daniel R. Ambruso, Stefan Jaeger, Kannappan Palaniappan, Kristen Lekstrom, Sharon H. Jackson, Aibing Wang, Ryuichi Sugamata, Howard E. Boudreau, Jaeyul Kwon, Devin J. Burke
Publikováno v:
Free Radical Biology and Medicine. 87:S114-S115
Autor:
Frans A. Kuypers, Stefanie Freeman, Carolina Gonzalez-Aller, Lori A. Rinckel, Patrick J. Leavey, Michael Kleinberg, Daniel W. Ambruso, Gail Thurman, Daniel R. Ambruso
Publikováno v:
Journal of Biological Chemistry. 277:45181-45187
Production of toxic oxygen metabolites provides a mechanism for microbicidal activity of the neutrophil. The NADPH oxidase enzyme system initiates the production of oxygen metabolites by reducing oxygen to form superoxide anion (O(2)()). With stimula
Autor:
Bernie Dharan, Julie Hicks, Kenneth C. Anderson, Mark A. Popovsky, Lynn Bemiller, Donna Skerrett, William C. Dickey, Irena Sniecinski, Karen K. Ballen, Mary O'Neill, Richard Lottenberg, Daniel R. Ambruso, Celso Bianco, John R. Wingard
Publikováno v:
Transfusion. 42:1279-1284
BACKGROUND: Umbilical cord blood is an alternative peripheral blood progenitor cell source for patients who need transplantation. A presumed advantage of cord blood is the ability to increase minority recruitment. STUDY DESIGN AND METHODS: The racial
Publikováno v:
Blood. 128:1328-1328
The cytokine IFN-γ is used as a drug to treat chronic granulomatous disease (CGD), hyperimmunoglobulin E syndromes and osteopetrosis. The goal of this study was to better understand how IFN-γmight support PMN function in these diseases, and to obta
Publikováno v:
Blood. 128:1026-1026
Introduction: Most information about the immunoregulatory functions of INF-γ has focused on the interaction with the adaptive immune system and less is reported about neutrophil function. Furthermore, the majority of studies with neutrophils evaluat