Zobrazeno 81 - 90
of 729
pro vyhledávání: '"Daniel, H Geschwind"'
Autor:
Chloe C. Y. Wong, Gokul Ramaswami, Jillian R. Haney, Michael J. Gandal, Jerry C. Wang, Daniel H. Geschwind, Jonathan Mill, Shyam Prabhakar, Wenjie Sun, Hyejung Won
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Nature communications, vol 11, iss 1
Nature Communications
Nature communications, vol 11, iss 1
Nature Communications
Autism spectrum disorder (ASD) is a phenotypically and genetically heterogeneous neurodevelopmental disorder. Despite this heterogeneity, previous studies have shown patterns of molecular convergence in post-mortem brain tissue from autistic subjects
The UCLA ATLAS Community Health Initiative: promoting precision health research in a diverse biobank
Autor:
Ruth Johnson, Yi Ding, Arjun Bhattacharya, Alec Chiu, Clara Lajonchere, Daniel H. Geschwind, Bogdan Pasaniuc
The UCLA ATLAS Community Health Initiative (ATLAS) has an initial target to recruit 150,000 participants from across the UCLA Health system, with the goal of creating a genomic database to accelerate precision medicine efforts in California. This ini
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca77d4fcd6eb610ef5749a406c74c2ab
https://doi.org/10.1101/2022.02.12.22270895
https://doi.org/10.1101/2022.02.12.22270895
Autor:
Tara E. Tracy, Jesus Madero-Pérez, Danielle L. Swaney, Timothy S. Chang, Michelle Moritz, Csaba Konrad, Michael E. Ward, Erica Stevenson, Ruth Hüttenhain, Grant Kauwe, Maria Mercedes, Lauren Sweetland-Martin, Xu Chen, Sue-Ann Mok, Man Ying Wong, Maria Telpoukhovskaia, Sang-Won Min, Chao Wang, Peter Dongmin Sohn, Jordie Martin, Yungui Zhou, Wenjie Luo, John Q. Trojanowski, Virginia M.Y. Lee, Shiaoching Gong, Giovanni Manfredi, Giovanni Coppola, Nevan J. Krogan, Daniel H. Geschwind, Li Gan
Publikováno v:
Cell, vol 185, iss 4
Tau (MAPT) drives neuronal dysfunction in Alzheimer disease (AD) and other tauopathies. To dissect the underlying mechanisms, we combined an engineered ascorbic acid peroxidase (APEX) approach with quantitative affinity purification mass spectrometry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe7c2ab524e7117a3fe6db828aa20a56
https://escholarship.org/uc/item/9tw4v44t
https://escholarship.org/uc/item/9tw4v44t
Autor:
Feng Tian, Yuyan Cheng, Songlin Zhou, Qianbin Wang, Aboozar Monavarfeshani, Kun Gao, Weiqian Jiang, Riki Kawaguchi, Qing Wang, Mingjun Tang, Ryan Donahue, Huyan Meng, Anne Jacobi, Jiani Yin, Xinyi Cai, Shane Hegarty, Joanna Stanicka, Phillip Dmitriev, Daniel Taub, Clifford J. Woolf, Joshua R. Sanes, Daniel H. Geschwind, Zhigang He
SUMMARYNeurodegenerative diseases are characterized by neuronal death and regenerative failure. However, gene regulatory programs governing how initial neuronal injuries lead to neuronal death remain poorly understood. In adult mice, optic nerve crus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::85d49e5c1742ce8c2cd133ca9ab029e5
https://doi.org/10.1101/2022.01.20.477004
https://doi.org/10.1101/2022.01.20.477004
Autor:
Xabier Calle Sanchez, Simone Montalbano, Morteza Vaez, Morten Dybdahl Krebs, Jonas Bygbjerg-Grauholm, Preben B. Mortensen, Anders D. Børglum, David M. Hougaard, Merete Nordentoft, Daniel H. Geschwind, Alfonso Buil, Andrew J. Schork, Wesley K. Thompson, Armin Raznahan, Dorte Helenius, Thomas Werge, Andrés Ingason
Publikováno v:
SSRN Electronic Journal.
Autor:
Erna A. van Niekerk, Riki Kawaguchi, Camila Marques de Freria, Kimberly Groeniger, Maria C. Marchetto, Sebastian Dupraz, Frank Bradke, Daniel H. Geschwind, Fred H. Gage, Mark H. Tuszynski
Publikováno v:
Cell reports / Methods 2(7), 100255 (2022). doi:10.1016/j.crmeth.2022.100255
Neuronal cultures provide a basis for reductionist insights that rely on molecular and pharmacological manipulation. However, the inability to culture mature adult CNS neurons limits our understanding of adult neuronal physiology. Here, we report met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9db86614027c42e6b84b6c0a02c87273
Autor:
Ngan Pan Bennett Au, Gajendra Kumar, Pallavi Asthana, Fuying Gao, Riki Kawaguchi, Raymond Chuen Chung Chang, Kwok Fai So, Yang Hu, Daniel H. Geschwind, Giovanni Coppola, Chi Him Eddie Ma
Publikováno v:
NPJ Regenerative medicine. 7(1)
Adult mammalian injured axons regenerate over short-distance in the peripheral nervous system (PNS) while the axons in the central nervous system (CNS) are unable to regrow after injury. Here, we demonstrated that Lycium barbarum polysaccharides (LBP
Autor:
Lucy H. Funk, Ana-Maria Iosif, Jeffrey Bennett, Amy M. Ryan, Richard J. Maddock, Roza M. Vlasova, Douglas J. Rowland, Cynthia M. Schumann, Judy Van de Water, David G. Amaral, Tyler A. Lesh, Martin Styner, Shuai Chen, Cameron S. Carter, Takeshi Murai, Daniel H. Geschwind, Michael J. Gandal, A. Kimberley McAllister, Melissa D. Bauman, Casey E. Hogrefe
Publikováno v:
J Neurosci
The Journal of neuroscience : the official journal of the Society for Neuroscience, vol 41, iss 48
The Journal of neuroscience : the official journal of the Society for Neuroscience, vol 41, iss 48
Human epidemiological studies implicate exposure to infection during gestation in the etiology of neurodevelopmental disorders. Animal models of maternal immune activation (MIA) have identified the maternal immune response as the critical link betwee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81a8b5013d4c019fa5b18a3540d954b4
https://europepmc.org/articles/PMC8638691/
https://europepmc.org/articles/PMC8638691/
Autor:
Julio C. Rojas, Hilary W. Heuer, Weiping Chen, Julie Czerkowicz, Danielle Graham, Leah K. Forsberg, Danielle Brushaber, Brian Appleby, Eliana Marisa Ramos, Giovanni Coppolla, Yvette M. Bordelon, Hugo Botha, Brad C. Dickerson, Dennis W. Dickson, Kimiko Domoto‐Reilly, Anne M. Fagan, Julie A. Fields, Jamie C. Fong, Tatiana M. Foroud, Doug R. Galasko, Ralitza H. Gavrilova, Daniel H. Geschwind, Nupur Ghoshal, Jill Goldman, Neill R. Graff‐Radford, Jonathan Graff‐Radford, Ian Grant, Murray Grossman, Ging‐Yuek Robin Hsiung, Eric J. Huang, Edward D. Huey, David J. Irwin, David T. Jones, Kejal Kantarci, David S. Knopman, John Kornak, Walter K. Kremers, Maria I. Lapid, Gabriel C. Leger, Irene Litvan, Peter A. Ljubenkov, Diane E. Lucente, Ian R Mackenzie, Joseph C. Masdeu, Corey T. McMillan, Mario F. Mendez, Bruce L. Miller, Toji Miyagawa, Chiadi U. Onyike, Belen Pascual, Otto Pedraza, Leonard Petrucelli, Rosa Rademakers, Katherine P. Rankin, Katya Rascovsky, Jessica E. Rexach, Aaron Ritter, Erik D. Roberson, Rodolfo Savica, William W. Seeley, Adam M. Staffaroni, Maria Carmela Tartaglia, Arthur W. Toga, Sandra Weintraub, Bonnie Wong, Zbigniew Wszolek, Lawren Vandevrede, Bradley F. Boeve, Howard J. Rosen, Adam L. Boxer
Publikováno v:
Alzheimer's & Dementia. 17
Autor:
Julio C. Rojas, Lawren Vandevrede, Hilary W. Heuer, Gianina Toller, Elisabeth H. Thijssen, Nicholas Proctor, Leah K. Forsberg, Danielle Brushaber, Eliana Marisa Ramos, Giovanni Coppola, Brian Appleby, Yvette M. Bordelon, Hugo Botha, Brad C. Dickerson, Dennis W. Dickson, Kimiko Domoto‐Reilly, Anne M. Fagan, Julie A. Fields, Jamie C. Fong, Tatiana M. Foroud, Doug R. Galasko, Ralitza H. Gavrilova, Daniel H. Geschwind, Nupur Ghoshal, Jill Goldman, Neill R. Graff‐Radford, Jonathan Graff‐Radford, Ian Grant, Murray Grossman, Ging‐Yuek Robin Hsiung, Eric J. Huang, Edward D. Huey, David J. Irwin, David T. Jones, Kejal Kantarci, David S. Knopman, John Kornak, Walter K. Kremers, Maria I. Lapid, Gabriel C. Leger, Irene Litvan, Peter A. Ljubenkov, Diane E. Lucente, Ian R. Mackenzie, Joseph C. Masdeu, Corey T. McMillan, Mario Mendez, Bruce L. Miller, Toji Miyagawa, Chiadi U. Onyike, Belen Pascual, Otto Pedraza, Leonard Petrucelli, Rosa Rademakers, Katherine P. Rankin, Katya Rascovsky, Jessica E. Rexach, Aaron Ritter, Erik D. Roberson, Rodolfo Savica, William W. Seeley, Adam M. Staffaroni, Maria Carmela Trataglia, Arthur W. Toga, Sandra Weintraub, Bonnie Wong, Zbigniew Wszolek, Jeffrey L. Dage, Bradley F. Boeve, Howard J. Rosen, Adam L. Boxer
Publikováno v:
Alzheimer's & Dementia. 17