Zobrazeno 91 - 100
of 323
pro vyhledávání: '"Dan E Arking"'
Autor:
Vamsee Pillalamarri, Dan E. Arking, Brian O'Rourke, Ryan J. Longchamps, Christina A. Castellani, Eliseo Guallar, Stephanie Y. Yang
Publikováno v:
Paediatrics Publications
Genome Res
Genome Res
BackgroundMitochondrial DNA copy number (mtDNA-CN) can be used as a proxy for mitochondrial function and is associated with a number of aging-related diseases. However, it is unclear how mtDNA-CN measured in blood can reflect risk for diseases that p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4914b9467dab70b35a22b17781cdddcd
https://ir.lib.uwo.ca/paedpub/947
https://ir.lib.uwo.ca/paedpub/947
Autor:
Thomas D. Rea, Spencer Rosero, Mehmet K. Aktas, Dan E. Arking, Nona Sotoodehnia, Arwa Younis, Peter J. Kudenchuk, Valentina Kutyifa, Scott McNitt, Wojciech Zareba, Bronislava Polonsky, Ilan Goldenberg
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Sex differences in outcome have been reported in patients with congenital long QT syndrome. We aimed to report on the incidence of time‐dependent life‐threatening events in male and female patients with long QT syndrome with an implant
Autor:
Traci M. Bartz, Penglong Wang, Josef Coresh, Eric Boerwinkle, Daniel Levy, Kent D. Taylor, Jan Bressler, Dan E. Arking, Christina A. Castellani, Nathan Pankratz, Brian O'Rourke, Eliseo Guallar, Nona Sotoodehnia, Jason A. Sumpter, Charles E. Newcomb, Myriam Fornage, Adrienne Tin, John A. Lane, James S. Pankow, James S. Floyd, Chunyu Liu, Megan L. Grove, Jennifer A. Brody, Ryan J. Longchamps
Publikováno v:
Paediatrics Publications
Genome Medicine
Genome Medicine, Vol 12, Iss 1, Pp 1-17 (2020)
Genome Medicine
Genome Medicine, Vol 12, Iss 1, Pp 1-17 (2020)
Background Mitochondrial DNA copy number (mtDNA-CN) has been associated with a variety of aging-related diseases, including all-cause mortality. However, the mechanism by which mtDNA-CN influences disease is not currently understood. One such mechani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90c87b7c6a4547e6e82b613fb727a92c
https://ir.lib.uwo.ca/paedpub/949
https://ir.lib.uwo.ca/paedpub/949
Autor:
Alvaro Alonso, Eliseo Guallar, Nona Sotoodehnia, Yun Soo Hong, Wendy Post, Ryan J. Longchamps, Dan E. Arking, Traci M. Bartz, John A. Lane, Di Zhao, Brian O'Rourke, Nathan Pankratz, Henry J. Lin, Jerome I. Rotter, Christina A. Castellani, Susan R. Heckbert, Stephanie Y. Yang
Publikováno v:
BMC Medicine, Vol 18, Iss 1, Pp 1-11 (2020)
BMC Medicine
BMC medicine, vol 18, iss 1
Paediatrics Publications
BMC Medicine
BMC medicine, vol 18, iss 1
Paediatrics Publications
Background Mechanistic studies suggest that mitochondria DNA (mtDNA) dysfunction may be associated with increased risk of atrial fibrillation (AF). The association between mtDNA copy number (mtDNA-CN) and incident AF in the general population, howeve
Autor:
Aditya Surapaneni, Nilanjan Chatterjee, Dan E. Arking, Jingsha Chen, Josef Coresh, Adrienne Tin, Morgan E. Grams, Bing Yu, Anna Köttgen, Jin Jin, Linda Zhou, Zhi Yu, Ron C. Hoogeveen, Christie M. Ballantyne
Genome-wide association studies (GWAS) have revealed numerous loci for kidney function (estimated glomerular filtration rate, eGFR). The relationship of polygenic predictors of eGFR, risk of incident adverse kidney outcomes, and the plasma proteome i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe913060f97f41ae6004b93f935aedf7
https://doi.org/10.1101/2020.09.05.284265
https://doi.org/10.1101/2020.09.05.284265
Autor:
Colleen M. Sitlani, Eimear E. Kenny, Yii-Der Ida Chen, Chani J. Hodonsky, Jerome I. Rotter, Rahul Gondalia, Xiuqing Guo, Lucia A. Hindorff, Alex P. Reiner, Heather M. Highland, Charles Kooperberg, Elsayed Z. Soliman, Nona Sotoodehnia, Susan R. Heckbert, Ulrike Peters, Wendy Post, Ralph V. Shohet, Ran Tao, Kari E. North, Amanda A. Seyerle, Dan E. Arking, Genevieve L. Wojcik, Kent D. Taylor, Eric A. Whitsel, Antoine R Baldassari, Jie Yao, Robert C. Kaplan, Henry J. Lin, Mariaelisa Graff, Steven Buyske, Christy L. Avery, Dawood Darbar
Publikováno v:
Circulation. Genomic and precision medicine, vol 13, iss 4
Circ Genom Precis Med
Circ Genom Precis Med
Background: We examined how expanding electrocardiographic trait genome-wide association studies to include ancestrally diverse populations, prioritize more precise phenotypic measures, and evaluate evidence for shared genetic effects enabled the det
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca17ca2bc52c085ae3d1ef0ce99c7fa6
https://escholarship.org/uc/item/70k449r8
https://escholarship.org/uc/item/70k449r8
Autor:
Lisa W. Martin, Tuomas O. Kilpeläinen, Xiuqing Guo, Kurt Lohman, Ching-Ti Liu, Jerome I. Rotter, Pirjo Komulainen, Lili Milani, Ilja M. Nolte, Yuri Milaneschi, Andres Metspalu, Yii-Der Ida Chen, Tõnu Esko, Jovia L. Nierenberg, Mika Kähönen, Marjan Ilkov, Dennis O. Mook-Kanamori, Karen Schwander, W. James Gauderman, Hanfei Xu, Vilmundur Gudnason, Alisa K. Manning, Gudny Eiriksdottir, David R. Hillman, Elise Lim, Hugues Aschard, John M. Starr, Michael R. Brown, Alanna C. Morrison, Eric Boerwinkle, Stefan Weiss, Maris Alver, Konstantin Strauch, Thomas Meitinger, Tuomo Rankinen, Timo A. Lakka, Harold Snieder, Stephen S. Rich, Yun Ju Sung, Diana van Heemst, Wanqing Wen, Marcus Dörr, Peter J. van der Most, Terho Lehtimäki, Nora Franceschini, Treva Rice, Amy R. Bentley, Dan E. Arking, Susan Redline, Nienke R. Biermasz, Sarah E. Harris, Melanie Waldenberger, Claude Bouchard, M. Arfan Ikram, Walter Palmas, Lynne E. Wagenknecht, Bruce M. Psaty, Daniel Levy, Cornelia M. van Duijn, Joshua C. Bis, Kelly A. Hall, José Eduardo Krieger, Tanika N. Kelly, Kari E. North, Brigitte Kühnel, Phyllis C. Zee, Melissa A. Richard, Lyle J. Palmer, Till Roenneberg, Alexandre C. Pereira, Yongmei Liu, Andrea R. V. R. Horimoto, Jie Yao, Han Chen, Jiang He, Pamela J. Schreiner, Patricia B. Munroe, Wei Zheng, Charles Kooperberg, Paul S. de Vries, Ana Barac, Rainer Rauramaa, Leo-Pekka Lyytikäinen, James M. Shikany, Brian E. Cade, Christian Gieger, Stephen Sidney, Alan B. Zonderman, Tamar Sofer, Chuan Gao, Thomas W. Winkler, Xiao-Ou Shu, Ian J. Deary, Uwe Völker, RJ Waken, Heming Wang, Myriam Fornage, Brenda W.J.H. Penninx, Gregory P. Wilson, Dina Vojinovic, Robert B. Wallace, Kenneth Rice, Ervin R. Fox, Jeffrey R. O'Connell, Annemarie I. Luik, Traci M. Bartz, Xiaofeng Zhu, Najaf Amin, Nicholette D. Palmer, Sami Heikkinen, Kumaraswamynaidu Chitrala, Raymond Noordam, Jiwon Lee, André G. Uitterlinden, Sutapa Mukherjee, Hans J. Grabe, Mario Sims, Sina A. Gharib, Daniel J. Gottlieb, Dabeeru C. Rao, Annette Peters, Reedik Mägi, Solomon K. Musani, Michele K. Evans, Lenore J. Launer
Publikováno v:
Mol Psychiatry
Molecular Psychiatry, 26(11), 6293-6304. SPRINGERNATURE
Molecular Psychiatry
Molecular Psychiatry, 2021, 26 (11), pp.6293-6304. ⟨10.1038/s41380-021-01087-0⟩
Molecular Psychiatry. Nature Publishing Group
Wang, H, Noordam, R, Cade, B E, Schwander, K, Winkler, T W, Lee, J, Sung, Y J, Bentley, A R, Manning, A K, Aschard, H, Kilpeläinen, T O, Ilkov, M, Brown, M R, Horimoto, A R, Richard, M, Bartz, T M, Vojinovic, D, Lim, E, Nierenberg, J L, Liu, Y, Chitrala, K, Rankinen, T, Musani, S K, Franceschini, N, Rauramaa, R, Alver, M, Zee, P C, Harris, S E, van der Most, P J, Nolte, I M, Munroe, P B, Palmer, N D, Kühnel, B, Weiss, S, Wen, W, Hall, K A, Lyytikäinen, L-P, O'Connell, J, Eiriksdottir, G, Launer, L J, de Vries, P S, Arking, D E, Chen, H, Boerwinkle, E, Krieger, J E, Schreiner, P J, Sidney, S, Shikany, J M, Rice, K, Chen, Y-D I, Gharib, S A, Bis, J C, Luik, A I, Ikram, M A, Uitterlinden, A G, Amin, N, Xu, H, Levy, D, He, J, Lohman, K K, Zonderman, A B, Rice, T K, Sims, M, Wilson, G, Sofer, T, Rich, S S, Palmas, W, Yao, J, Guo, X, Rotter, J I, Biermasz, N R, Mook-Kanamori, D O, Martin, L W, Barac, A, Wallace, R B, Gottlieb, D J, Komulainen, P, Heikkinen, S, Mägi, R, Milani, L, Metspalu, A, Starr, J M, Milaneschi, Y, Waken, R J, Gao, C, Waldenberger, M, Peters, A, Strauch, K, Meitinger, T, Roenneberg, T, Völker, U, Dörr, M, Shu, X-O, Mukherjee, S, Hillman, D R, Kähönen, M, Wagenknecht, L E, Gieger, C, Grabe, H J, Zheng, W, Palmer, L J, Lehtimäki, T, Gudnason, V, Morrison, A C, Pereira, A C, Fornage, M, Psaty, B M, van Duijn, C M, Liu, C-T, Kelly, T N, Evans, M K, Bouchard, C, Fox, E R, Kooperberg, C, Zhu, X, Lakka, T A, Esko, T, North, K E, Deary, I J, Snieder, H, Penninx, B W J H, Gauderman, W J, Rao, D C, Redline, S & van Heemst, D 2021, ' Multi-ancestry genome-wide gene-sleep interactions identify novel loci for blood pressure ', Molecular Psychiatry . https://doi.org/10.1038/s41380-021-01087-0
Molecular Psychiatry, 26(11), 6293-6304. Nature Publishing Group
Wang, H, Noordam, R, Cade, B E, Schwander, K, Winkler, T W, Lee, J, Sung, Y J, Bentley, A R, Manning, A K, Aschard, H, Kilpeläinen, T O, Ilkov, M, Brown, M R, Horimoto, A R, Richard, M, Bartz, T M, Vojinovic, D, Lim, E, Nierenberg, J L, Liu, Y, Chitrala, K, Rankinen, T, Musani, S K, Franceschini, N, Rauramaa, R, Alver, M, Zee, P C, Harris, S E, van der Most, P J, Nolte, I M, Munroe, P B, Palmer, N D, Kühnel, B, Weiss, S, Wen, W, Hall, K A, Lyytikäinen, L-P, O'Connell, J, Eiriksdottir, G, Launer, L J, de Vries, P S, Arking, D E, Chen, H, Boerwinkle, E, Krieger, J E, Schreiner, P J, Sidney, S, Shikany, J M, Rice, K, Chen, Y-D I, Gharib, S A, Bis, J C, Luik, A I, Ikram, M A, Uitterlinden, A G, Amin, N, Xu, H, Levy, D, He, J, Lohman, K K, Zonderman, A B, Rice, T K, Sims, M, Wilson, G, Sofer, T, Rich, S S, Palmas, W, Yao, J, Guo, X, Rotter, J I, Biermasz, N R, Mook-Kanamori, D O, Martin, L W, Barac, A, Wallace, R B, Gottlieb, D J, Komulainen, P, Heikkinen, S, Mägi, R, Milani, L, Metspalu, A, Starr, J M, Milaneschi, Y, Waken, R J, Gao, C, Waldenberger, M, Peters, A, Strauch, K, Meitinger, T, Roenneberg, T, Völker, U, Dörr, M, Shu, X-O, Mukherjee, S, Hillman, D R, Kähönen, M, Wagenknecht, L E, Gieger, C, Grabe, H J, Zheng, W, Palmer, L J, Lehtimäki, T, Gudnason, V, Morrison, A C, Pereira, A C, Fornage, M, Psaty, B M, van Duijn, C M, Liu, C-T, Kelly, T N, Evans, M K, Bouchard, C, Fox, E R, Kooperberg, C, Zhu, X, Lakka, T A, Esko, T, North, K E, Deary, I J, Snieder, H, Penninx, B W J H, Gauderman, W J, Rao, D C, Redline, S & van Heemst, D 2021, ' Multi-ancestry genome-wide gene-sleep interactions identify novel loci for blood pressure ', Molecular Psychiatry, vol. 26, pp. 6293-6304 . https://doi.org/10.1038/s41380-021-01087-0
Molecular Psychiatry, Nature Publishing Group, In press, ⟨10.1038/s41380-021-01087-0⟩
Wang, H, Noordam, R, Cade, B E, Schwander, K, Winkler, T W, Lee, J, Sung, Y J, Bentley, A R, Manning, A K, Aschard, H, Kilpeläinen, T O, Ilkov, M, Brown, M R, Horimoto, A R, Richard, M, Bartz, T M, Vojinovic, D, Lim, E, Nierenberg, J L, Liu, Y, Chitrala, K, Rankinen, T, Musani, S K, Franceschini, N, Rauramaa, R, Alver, M, Zee, P C, Harris, S E, van der Most, P J, Nolte, I M, Munroe, P B, Palmer, N D, Kühnel, B, Weiss, S, Wen, W, Hall, K A, Lyytikäinen, L-P, O’Connell, J, Eiriksdottir, G, Launer, L J, de Vries, P S, Arking, D E, Chen, H, Boerwinkle, E, Krieger, J E, Schreiner, P J, Sidney, S, Shikany, J M, Rice, K, Chen, Y-D I, Gharib, S A, Bis, J C, Luik, A I, Ikram, M A, Uitterlinden, A G, Amin, N, Xu, H, Levy, D, He, J, Lohman, K K, Zonderman, A B, Rice, T K, Sims, M, Wilson, G, Sofer, T, Rich, S S, Palmas, W, Yao, J, Guo, X, Rotter, J I, Biermasz, N R, Mook-Kanamori, D O, Martin, L W, Barac, A, Wallace, R B, Gottlieb, D J, Komulainen, P, Heikkinen, S, Mägi, R, Milani, L, Metspalu, A, Starr, J M, Milaneschi, Y, Waken, R J, Gao, C, Waldenberger, M, Peters, A, Strauch, K, Meitinger, T, Roenneberg, T, Völker, U, Dörr, M, Shu, X-O, Mukherjee, S, Hillman, D R, Kähönen, M, Wagenknecht, L E, Gieger, C, Grabe, H J, Zheng, W, Palmer, L J, Lehtimäki, T, Gudnason, V, Morrison, A C, Pereira, A C, Fornage, M, Psaty, B M, van Duijn, C M, Liu, C-T, Kelly, T N, Evans, M K, Bouchard, C, Fox, E R, Kooperberg, C, Zhu, X, Lakka, T A, Esko, T N, North, K E, Deary, I J, Snieder, H, Penninx, B W J H, Gauderman, W J, Rao, D C, Redline, S & van Heemst, D 2021, ' Multi-ancestry genome-wide gene–sleep interactions identify novel loci for blood pressure ', Molecular Psychiatry, vol. 26, no. 11, pp. 6293-6304 . https://doi.org/10.1038/s41380-021-01087-0
Molecular Psychiatry, 26(11), 6293-6304. SPRINGERNATURE
Molecular Psychiatry
Molecular Psychiatry, 2021, 26 (11), pp.6293-6304. ⟨10.1038/s41380-021-01087-0⟩
Molecular Psychiatry. Nature Publishing Group
Wang, H, Noordam, R, Cade, B E, Schwander, K, Winkler, T W, Lee, J, Sung, Y J, Bentley, A R, Manning, A K, Aschard, H, Kilpeläinen, T O, Ilkov, M, Brown, M R, Horimoto, A R, Richard, M, Bartz, T M, Vojinovic, D, Lim, E, Nierenberg, J L, Liu, Y, Chitrala, K, Rankinen, T, Musani, S K, Franceschini, N, Rauramaa, R, Alver, M, Zee, P C, Harris, S E, van der Most, P J, Nolte, I M, Munroe, P B, Palmer, N D, Kühnel, B, Weiss, S, Wen, W, Hall, K A, Lyytikäinen, L-P, O'Connell, J, Eiriksdottir, G, Launer, L J, de Vries, P S, Arking, D E, Chen, H, Boerwinkle, E, Krieger, J E, Schreiner, P J, Sidney, S, Shikany, J M, Rice, K, Chen, Y-D I, Gharib, S A, Bis, J C, Luik, A I, Ikram, M A, Uitterlinden, A G, Amin, N, Xu, H, Levy, D, He, J, Lohman, K K, Zonderman, A B, Rice, T K, Sims, M, Wilson, G, Sofer, T, Rich, S S, Palmas, W, Yao, J, Guo, X, Rotter, J I, Biermasz, N R, Mook-Kanamori, D O, Martin, L W, Barac, A, Wallace, R B, Gottlieb, D J, Komulainen, P, Heikkinen, S, Mägi, R, Milani, L, Metspalu, A, Starr, J M, Milaneschi, Y, Waken, R J, Gao, C, Waldenberger, M, Peters, A, Strauch, K, Meitinger, T, Roenneberg, T, Völker, U, Dörr, M, Shu, X-O, Mukherjee, S, Hillman, D R, Kähönen, M, Wagenknecht, L E, Gieger, C, Grabe, H J, Zheng, W, Palmer, L J, Lehtimäki, T, Gudnason, V, Morrison, A C, Pereira, A C, Fornage, M, Psaty, B M, van Duijn, C M, Liu, C-T, Kelly, T N, Evans, M K, Bouchard, C, Fox, E R, Kooperberg, C, Zhu, X, Lakka, T A, Esko, T, North, K E, Deary, I J, Snieder, H, Penninx, B W J H, Gauderman, W J, Rao, D C, Redline, S & van Heemst, D 2021, ' Multi-ancestry genome-wide gene-sleep interactions identify novel loci for blood pressure ', Molecular Psychiatry . https://doi.org/10.1038/s41380-021-01087-0
Molecular Psychiatry, 26(11), 6293-6304. Nature Publishing Group
Wang, H, Noordam, R, Cade, B E, Schwander, K, Winkler, T W, Lee, J, Sung, Y J, Bentley, A R, Manning, A K, Aschard, H, Kilpeläinen, T O, Ilkov, M, Brown, M R, Horimoto, A R, Richard, M, Bartz, T M, Vojinovic, D, Lim, E, Nierenberg, J L, Liu, Y, Chitrala, K, Rankinen, T, Musani, S K, Franceschini, N, Rauramaa, R, Alver, M, Zee, P C, Harris, S E, van der Most, P J, Nolte, I M, Munroe, P B, Palmer, N D, Kühnel, B, Weiss, S, Wen, W, Hall, K A, Lyytikäinen, L-P, O'Connell, J, Eiriksdottir, G, Launer, L J, de Vries, P S, Arking, D E, Chen, H, Boerwinkle, E, Krieger, J E, Schreiner, P J, Sidney, S, Shikany, J M, Rice, K, Chen, Y-D I, Gharib, S A, Bis, J C, Luik, A I, Ikram, M A, Uitterlinden, A G, Amin, N, Xu, H, Levy, D, He, J, Lohman, K K, Zonderman, A B, Rice, T K, Sims, M, Wilson, G, Sofer, T, Rich, S S, Palmas, W, Yao, J, Guo, X, Rotter, J I, Biermasz, N R, Mook-Kanamori, D O, Martin, L W, Barac, A, Wallace, R B, Gottlieb, D J, Komulainen, P, Heikkinen, S, Mägi, R, Milani, L, Metspalu, A, Starr, J M, Milaneschi, Y, Waken, R J, Gao, C, Waldenberger, M, Peters, A, Strauch, K, Meitinger, T, Roenneberg, T, Völker, U, Dörr, M, Shu, X-O, Mukherjee, S, Hillman, D R, Kähönen, M, Wagenknecht, L E, Gieger, C, Grabe, H J, Zheng, W, Palmer, L J, Lehtimäki, T, Gudnason, V, Morrison, A C, Pereira, A C, Fornage, M, Psaty, B M, van Duijn, C M, Liu, C-T, Kelly, T N, Evans, M K, Bouchard, C, Fox, E R, Kooperberg, C, Zhu, X, Lakka, T A, Esko, T, North, K E, Deary, I J, Snieder, H, Penninx, B W J H, Gauderman, W J, Rao, D C, Redline, S & van Heemst, D 2021, ' Multi-ancestry genome-wide gene-sleep interactions identify novel loci for blood pressure ', Molecular Psychiatry, vol. 26, pp. 6293-6304 . https://doi.org/10.1038/s41380-021-01087-0
Molecular Psychiatry, Nature Publishing Group, In press, ⟨10.1038/s41380-021-01087-0⟩
Wang, H, Noordam, R, Cade, B E, Schwander, K, Winkler, T W, Lee, J, Sung, Y J, Bentley, A R, Manning, A K, Aschard, H, Kilpeläinen, T O, Ilkov, M, Brown, M R, Horimoto, A R, Richard, M, Bartz, T M, Vojinovic, D, Lim, E, Nierenberg, J L, Liu, Y, Chitrala, K, Rankinen, T, Musani, S K, Franceschini, N, Rauramaa, R, Alver, M, Zee, P C, Harris, S E, van der Most, P J, Nolte, I M, Munroe, P B, Palmer, N D, Kühnel, B, Weiss, S, Wen, W, Hall, K A, Lyytikäinen, L-P, O’Connell, J, Eiriksdottir, G, Launer, L J, de Vries, P S, Arking, D E, Chen, H, Boerwinkle, E, Krieger, J E, Schreiner, P J, Sidney, S, Shikany, J M, Rice, K, Chen, Y-D I, Gharib, S A, Bis, J C, Luik, A I, Ikram, M A, Uitterlinden, A G, Amin, N, Xu, H, Levy, D, He, J, Lohman, K K, Zonderman, A B, Rice, T K, Sims, M, Wilson, G, Sofer, T, Rich, S S, Palmas, W, Yao, J, Guo, X, Rotter, J I, Biermasz, N R, Mook-Kanamori, D O, Martin, L W, Barac, A, Wallace, R B, Gottlieb, D J, Komulainen, P, Heikkinen, S, Mägi, R, Milani, L, Metspalu, A, Starr, J M, Milaneschi, Y, Waken, R J, Gao, C, Waldenberger, M, Peters, A, Strauch, K, Meitinger, T, Roenneberg, T, Völker, U, Dörr, M, Shu, X-O, Mukherjee, S, Hillman, D R, Kähönen, M, Wagenknecht, L E, Gieger, C, Grabe, H J, Zheng, W, Palmer, L J, Lehtimäki, T, Gudnason, V, Morrison, A C, Pereira, A C, Fornage, M, Psaty, B M, van Duijn, C M, Liu, C-T, Kelly, T N, Evans, M K, Bouchard, C, Fox, E R, Kooperberg, C, Zhu, X, Lakka, T A, Esko, T N, North, K E, Deary, I J, Snieder, H, Penninx, B W J H, Gauderman, W J, Rao, D C, Redline, S & van Heemst, D 2021, ' Multi-ancestry genome-wide gene–sleep interactions identify novel loci for blood pressure ', Molecular Psychiatry, vol. 26, no. 11, pp. 6293-6304 . https://doi.org/10.1038/s41380-021-01087-0
Long and short sleep duration are associated with elevated blood pressure (BP), possibly through effects on molecular pathways that influence neuroendocrine and vascular systems. To gain new insights into the genetic basis of sleep-related BP variati
Autor:
Laura Loehr, Ryan J. Longchamps, Christina A. Castellani, Eric Boerwinkle, Dan E. Arking, Di Zhao, Megan L. Grove, Eliseo Guallar, Kunihiro Matsushita, Patricia P. Chang, Yun Soo Hong
Publikováno v:
Paediatrics Publications
Circulation
Circulation
BackgroundThe association between mitochondrial DNA-copy number (mtDNA-CN) and incident heart failure (HF) in the general population is unclear.MethodsWe examined the association between mtDNA-CN and the risk of incident HF among 10,802 participants
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70caea93be03c3e11f188c7c004bbfb9
https://ir.lib.uwo.ca/paedpub/952
https://ir.lib.uwo.ca/paedpub/952
Autor:
Yongmei Liu, Tuomas O. Kilpeläinen, Kenneth Rice, Ching-Ti Liu, Jin-Fang Chai, Donna K. Arnett, Dhananjay Vaidya, Nicholette D. Palmer, Lili Milani, Yuri Milaneschi, Leo-Pekka Lyytikäinen, Colleen M. Sitlani, Richard S. Cooper, Gudny Eiriksdottir, Daniel Levy, Jerome I. Rotter, Lihua Wang, Sven Bergmann, Yih Chung Tham, Thomas Meitinger, Lynne E. Wagenknecht, Virginia Fisher, Babatunde L. Salako, Vilmundur Gudnason, Bamidele O. Tayo, Caizheng Yu, Barry I. Freedman, Muhammad Riaz, Kaare Christensen, Ulrich Broeckel, W. James Gauderman, Massimiliano Cocca, Eric Boerwinkle, Meian He, Rob M. van Dam, M. Arfan Ikram, Lisa de las Fuentes, Jiang He, Aldi T. Kraja, Nancy L. Pedersen, Albert V. Smith, Woon-Puay Koh, Bernardo L. Horta, He Gao, Traci M. Bartz, Mike A. Nalls, Federica Laguzzi, Raymond Noordam, Paul M. Ridker, Tien Yin Wong, Patricia B. Munroe, Paul S. de Vries, Adolfo Correa, Maris Alver, Dan E. Arking, Colin A. McKenzie, John M. Starr, Chi Charles Gu, Dongfeng Gu, Stefan Weiss, Patricia A. Peyser, Jessica D. Faul, Xu Chen, Jill M. Norris, Patrik K. E. Magnusson, Tamar Sofer, Ioanna Ntalla, Xiuqing Guo, Paul Elliott, Lawrence F. Bielak, Konstantin Strauch, Xueling Sim, Norihiro Kato, Evangelos Evangelou, Ilja M. Nolte, Steven C. Hunt, Mario Sims, Giorgia Girotto, Chuan Gao, Pamela J. Schreiner, Philippe Froguel, Archie Campbell, Xiao-Ou Shu, Claude Bouchard, Kurt Lohman, David R. Weir, José Eduardo Krieger, Yii-Der Ida Chen, Rainer Rauramaa, Walter Palmas, Cornelia M. van Duijn, James M. Shikany, Michael M. Province, Jennifer A. Smith, Wei Zheng, Xiaofeng Zhu, Jianjun Liu, Ozren Polasek, Alexandre C. Pereira, Diane M. Becker, Kari E. North, Salman M. Tajuddin, Deng Xuan, Leslie J. Raffel, Jie Yao, Astrid Petersmann, Ervin F. Fox, Mark J. Caulfield, Daniel I. Chasman, Jasmin Divers, Claudia P. Cabrera, Rico Rueedi, M. Yldau van der Ende, Carl D. Langefeld, Mika Kähönen, Terrence Forrester, Tangchun Wu, Harold Snieder, Caroline Hayward, Tamara B. Harris, Fang-Chi Hsu, Helen R. Warren, Brenda W.J.H. Penninx, Chiea Chuen Khor, Ruifang Li-Gao, Changwei Li, Sami Heikkinen, Jeffrey R. O'Connell, Christian Gieger, Michele K. Evans, Ching-Yu Cheng, Jingjing Liang, Stephen B. Kritchevsky, Gregory L. Burke, Donald W. Bowden, Alexander Teumer, Marcus Dörr, Alanna C. Morrison, Jian-Min Yuan, Annette Peters, Dennis O. Mook-Kanamori, Pedro Marques-Vidal, Pirjo Komulainen, Lisa R. Yanek, Melanie Waldenberger, Alisa K. Manning, Charles N. Rotimi, Chew-Kiat Heng, Tõnu Esko, Franco Giulianini, Miao Li Chee, Treva Rice, David J. Porteous, Yechiel Friedlander, Bing Yu, Myriam Fornage, Karin Leander, Dina Vojinovic, Sharon L.R. Kardia, Xiaoyin Li, Najaf Amin, Karen Schwander, Thomas T. Perls, Oscar Leonel Rueda-Ochoa, Erin B. Ware, Ya Xing Wang, Sandosh Padmanabhan, H. Janaka de Silva, André G. Uitterlinden, Rajkumar Dorajoo, Bruna Gigante, Jennifer A. Brody, Paolo Gasparini, Maryam Kavousi, Wanqing Wen, Stephen Sidney, Alan B. Zonderman, Michael R. Brown, Tuomo Rankinen, Timo A. Lakka, Yun Ju Sung, Alaitz Poveda, Bruce M. Psaty, Terho Lehtimäki, Tanika N. Kelly, Igor Rudan, Brigitte Kühnel, Christopher P. Nelson, John M. C. Connell, Mickaël Canouil, Niek Verweij, Thomas W. Winkler, Ian J. Deary, Marco Brumat, Yize Li, Fumihiko Takeuchi, Wei Zhao, Andres Metspalu, Marguerite R. Irvin, David C. Liewald, Pim van der Harst, Hugues Aschard, Candace M. Kammerer, Melissa A. Richard, Adesola Ogunniyi, Wen Bin Wei, Morris A. Swertz, Fernando Pires Hartwig, Dabeeru C. Rao, Reedik Mägi, Solomon K. Musani, Mathilde Boissel, Jonathan Marten, Nilesh J. Samani, Amy R. Bentley, Sarah E. Harris, Charumathi Sabanayagam, Mary F. Feitosa, Jost B. Jonas, Andrea R. V. R. Horimoto, Paul W. Franks, E. Shyong Tai
Publikováno v:
Molecular Psychiatry, 26, 2111-2125. NATURE PUBLISHING GROUP
Molecular psychiatry
Molecular Psychiatry
Molecular Psychiatry, Nature Publishing Group, 2020, ⟨10.1038/s41380-020-0719-3⟩
Molecular Psychiatry, 26(6), 2111-2125. Nature Publishing Group
Molecular Psychiatry, 2020, ⟨10.1038/s41380-020-0719-3⟩
de las Fuentes, L, Sung, Y J, Noordam, R, Winkler, T, Feitosa, M F, Schwander, K, Bentley, A R, Brown, M R, Guo, X, Manning, A, Chasman, D I, Aschard, H, Bartz, T M, Bielak, L F, Campbell, A, Cheng, C Y, Dorajoo, R, Hartwig, F P, Horimoto, A R V R, Li, C, Li-Gao, R, Liu, Y, Marten, J, Musani, S K, Ntalla, I, Rankinen, T, Richard, M, Sim, X, Smith, A V, Tajuddin, S M, Tayo, B O, Vojinovic, D, Warren, H R, Xuan, D, Alver, M, Boissel, M, Chai, J F, Chen, X, Christensen, K, Divers, J, Evangelou, E, Gao, C, Girotto, G, Harris, S E, He, M, Hsu, F C, Kühnel, B, Laguzzi, F, Li, X, Lyytikäinen, L P, Nolte, I M, Poveda, A, Rauramaa, R, Riaz, M, Rueedi, R, Shu, X O, Snieder, H, Sofer, T, Takeuchi, F, Verweij, N, Ware, E B, Weiss, S, Yanek, L R, Amin, N, Arking, D E, Arnett, D K, Bergmann, S, Boerwinkle, E, Brody, J A, Broeckel, U, Brumat, M, Burke, G, Cabrera, C P, Canouil, M, Chee, M L, Chen, Y D I, Cocca, M, Connell, J, de Silva, H J, de Vries, P S, Eiriksdottir, G, Faul, J D, Fisher, V, Forrester, T, Fox, E F, Friedlander, Y, Gao, H, Gigante, B, Giulianini, F, Gu, C C, Gu, D, Harris, T B, He, J, Heikkinen, S, Heng, C K, Hunt, S, Ikram, M A, Irvin, M R, Kähönen, M, Kavousi, M, Khor, C C, Kilpeläinen, T O, Koh, W P, Komulainen, P, Kraja, A T, Krieger, J E, Langefeld, C D, Li, Y, Liang, J, Liewald, D C M, Liu, C T, Liu, J, Lohman, K K, Mägi, R, McKenzie, C A, Meitinger, T, Metspalu, A, Milaneschi, Y, Milani, L, Mook-Kanamori, D O, Nalls, M A, Nelson, C P, Norris, J M, O’Connell, J, Ogunniyi, A, Padmanabhan, S, Palmer, N D, Pedersen, N L, Perls, T, Peters, A, Petersmann, A, Peyser, P A, Polasek, O, Porteous, D J, Raffel, L J, Rice, T K, Rotter, J I, Rudan, I, Rueda-Ochoa, O L, Sabanayagam, C, Salako, B L, Schreiner, P J, Shikany, J M, Sidney, S S, Sims, M, Sitlani, C M, Smith, J A, Starr, J M, Strauch, K, Swertz, M A, Teumer, A, Tham, Y C, Uitterlinden, A G, Vaidya, D, van der Ende, M Y, Waldenberger, M, Wang, L, Wang, Y X, Wei, W B, Weir, D R, Wen, W, Yao, J, Yu, B, Yu, C, Yuan, J M, Zhao, W, Zonderman, A B, Becker, D M, Bowden, D W, Deary, I J, Dörr, M, Esko, T, Freedman, B I, Froguel, P, Gasparini, P, Gieger, C, Jonas, J B, Kammerer, C M, Kato, N, Lakka, T A, Leander, K, Lehtimäki, T, Magnusson, P K E, Marques-Vidal, P, Penninx, B W J H, Samani, N J, van der Harst, P, Wagenknecht, L E, Wu, T, Zheng, W, Zhu, X, Bouchard, C, Cooper, R S, Correa, A, Evans, M K, Gudnason, V, Hayward, C, Horta, B L, Kelly, T N, Kritchevsky, S B, Levy, D, Palmas, W R, Pereira, A C, Province, M M, Psaty, B M, Ridker, P M, Rotimi, C N, Tai, E S, van Dam, R M, van Duijn, C M, Wong, T Y, Rice, K, Gauderman, W J, Morrison, A C, North, K E, Kardia, S L R, Caulfield, M J, Elliott, P, Munroe, P B, Franks, P W, Rao, D C, Fornage, M & Lifelines Cohort Study 2021, ' Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci ', Molecular Psychiatry, vol. 26, no. 6, pp. 2111-2125 . https://doi.org/10.1038/s41380-020-0719-3
Molecular psychiatry, vol. 26, no. 6, pp. 2111-2125
de las Fuentes, L, Sung, Y J, Noordam, R, Winkler, T, Feitosa, M F, Schwander, K, Bentley, A R, Brown, M R, Guo, X, Manning, A, Chasman, D I, Aschard, H, Bartz, T M, Bielak, L F, Campbell, A, Cheng, C Y, Dorajoo, R, Hartwig, F P, Horimoto, A R V R, Li, C, Li-Gao, R, Liu, Y, Marten, J, Musani, S K, Ntalla, I, Rankinen, T, Richard, M, Sim, X, Smith, A V, Tajuddin, S M, Tayo, B O, Vojinovic, D, Warren, H R, Xuan, D, Alver, M, Boissel, M, Chai, J F, Chen, X, Christensen, K, Divers, J, Evangelou, E, Gao, C, Girotto, G, Harris, S E, He, M, Hsu, F C, Kühnel, B, Laguzzi, F, Li, X, Lyytikäinen, L P & Lifelines Cohort Study 2021, ' Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci ', Molecular Psychiatry, vol. 26, no. 6, pp. 2111-2125 . https://doi.org/10.1038/s41380-020-0719-3
Molecular Psychiatry, 26, 2111-2125. Nature Publishing Group
Molecular psychiatry
Molecular Psychiatry
Molecular Psychiatry, Nature Publishing Group, 2020, ⟨10.1038/s41380-020-0719-3⟩
Molecular Psychiatry, 26(6), 2111-2125. Nature Publishing Group
Molecular Psychiatry, 2020, ⟨10.1038/s41380-020-0719-3⟩
de las Fuentes, L, Sung, Y J, Noordam, R, Winkler, T, Feitosa, M F, Schwander, K, Bentley, A R, Brown, M R, Guo, X, Manning, A, Chasman, D I, Aschard, H, Bartz, T M, Bielak, L F, Campbell, A, Cheng, C Y, Dorajoo, R, Hartwig, F P, Horimoto, A R V R, Li, C, Li-Gao, R, Liu, Y, Marten, J, Musani, S K, Ntalla, I, Rankinen, T, Richard, M, Sim, X, Smith, A V, Tajuddin, S M, Tayo, B O, Vojinovic, D, Warren, H R, Xuan, D, Alver, M, Boissel, M, Chai, J F, Chen, X, Christensen, K, Divers, J, Evangelou, E, Gao, C, Girotto, G, Harris, S E, He, M, Hsu, F C, Kühnel, B, Laguzzi, F, Li, X, Lyytikäinen, L P, Nolte, I M, Poveda, A, Rauramaa, R, Riaz, M, Rueedi, R, Shu, X O, Snieder, H, Sofer, T, Takeuchi, F, Verweij, N, Ware, E B, Weiss, S, Yanek, L R, Amin, N, Arking, D E, Arnett, D K, Bergmann, S, Boerwinkle, E, Brody, J A, Broeckel, U, Brumat, M, Burke, G, Cabrera, C P, Canouil, M, Chee, M L, Chen, Y D I, Cocca, M, Connell, J, de Silva, H J, de Vries, P S, Eiriksdottir, G, Faul, J D, Fisher, V, Forrester, T, Fox, E F, Friedlander, Y, Gao, H, Gigante, B, Giulianini, F, Gu, C C, Gu, D, Harris, T B, He, J, Heikkinen, S, Heng, C K, Hunt, S, Ikram, M A, Irvin, M R, Kähönen, M, Kavousi, M, Khor, C C, Kilpeläinen, T O, Koh, W P, Komulainen, P, Kraja, A T, Krieger, J E, Langefeld, C D, Li, Y, Liang, J, Liewald, D C M, Liu, C T, Liu, J, Lohman, K K, Mägi, R, McKenzie, C A, Meitinger, T, Metspalu, A, Milaneschi, Y, Milani, L, Mook-Kanamori, D O, Nalls, M A, Nelson, C P, Norris, J M, O’Connell, J, Ogunniyi, A, Padmanabhan, S, Palmer, N D, Pedersen, N L, Perls, T, Peters, A, Petersmann, A, Peyser, P A, Polasek, O, Porteous, D J, Raffel, L J, Rice, T K, Rotter, J I, Rudan, I, Rueda-Ochoa, O L, Sabanayagam, C, Salako, B L, Schreiner, P J, Shikany, J M, Sidney, S S, Sims, M, Sitlani, C M, Smith, J A, Starr, J M, Strauch, K, Swertz, M A, Teumer, A, Tham, Y C, Uitterlinden, A G, Vaidya, D, van der Ende, M Y, Waldenberger, M, Wang, L, Wang, Y X, Wei, W B, Weir, D R, Wen, W, Yao, J, Yu, B, Yu, C, Yuan, J M, Zhao, W, Zonderman, A B, Becker, D M, Bowden, D W, Deary, I J, Dörr, M, Esko, T, Freedman, B I, Froguel, P, Gasparini, P, Gieger, C, Jonas, J B, Kammerer, C M, Kato, N, Lakka, T A, Leander, K, Lehtimäki, T, Magnusson, P K E, Marques-Vidal, P, Penninx, B W J H, Samani, N J, van der Harst, P, Wagenknecht, L E, Wu, T, Zheng, W, Zhu, X, Bouchard, C, Cooper, R S, Correa, A, Evans, M K, Gudnason, V, Hayward, C, Horta, B L, Kelly, T N, Kritchevsky, S B, Levy, D, Palmas, W R, Pereira, A C, Province, M M, Psaty, B M, Ridker, P M, Rotimi, C N, Tai, E S, van Dam, R M, van Duijn, C M, Wong, T Y, Rice, K, Gauderman, W J, Morrison, A C, North, K E, Kardia, S L R, Caulfield, M J, Elliott, P, Munroe, P B, Franks, P W, Rao, D C, Fornage, M & Lifelines Cohort Study 2021, ' Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci ', Molecular Psychiatry, vol. 26, no. 6, pp. 2111-2125 . https://doi.org/10.1038/s41380-020-0719-3
Molecular psychiatry, vol. 26, no. 6, pp. 2111-2125
de las Fuentes, L, Sung, Y J, Noordam, R, Winkler, T, Feitosa, M F, Schwander, K, Bentley, A R, Brown, M R, Guo, X, Manning, A, Chasman, D I, Aschard, H, Bartz, T M, Bielak, L F, Campbell, A, Cheng, C Y, Dorajoo, R, Hartwig, F P, Horimoto, A R V R, Li, C, Li-Gao, R, Liu, Y, Marten, J, Musani, S K, Ntalla, I, Rankinen, T, Richard, M, Sim, X, Smith, A V, Tajuddin, S M, Tayo, B O, Vojinovic, D, Warren, H R, Xuan, D, Alver, M, Boissel, M, Chai, J F, Chen, X, Christensen, K, Divers, J, Evangelou, E, Gao, C, Girotto, G, Harris, S E, He, M, Hsu, F C, Kühnel, B, Laguzzi, F, Li, X, Lyytikäinen, L P & Lifelines Cohort Study 2021, ' Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci ', Molecular Psychiatry, vol. 26, no. 6, pp. 2111-2125 . https://doi.org/10.1038/s41380-020-0719-3
Molecular Psychiatry, 26, 2111-2125. Nature Publishing Group
Educational attainment is widely used as a surrogate for socioeconomic status (SES). Low SES is a risk factor for hypertension and high blood pressure (BP). To identify novel BP loci, we performed multi-ancestry meta-analyses accounting for gene-educ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::554bda77ec4e9f3602722bf8e37ac4d7
https://doi.org/10.1038/s41380-020-0719-3
https://doi.org/10.1038/s41380-020-0719-3
Autor:
Patricia A. Peyser, Tamar Sofer, Joshua C. Bis, Ryan J. Longchamps, Susan R. Heckbert, Daniel Levy, Bharat Thyagarajan, Gonçalo R. Abecasis, Xiuqing Guo, Xue Liu, Sudha Seshadri, Laura M. Raffield, Jennifer A. Smith, Kent D. Taylor, Myriam Fornage, Eric Boerwinkle, Stephen S. Rich, Achilleas N. Pitsillides, Lawrence F. Bielak, Adolfo Correa, Dan E. Arking, Thomas W. Blackwell, Bruce M. Psaty, James G. Wilson, Ramachandran S. Vasan, Nathan Pankratz, Claudia L. Satizabal, Wei Zhao, Jerome I. Rotter, Chunyu Liu, Jun Ding, Kerri L. Wiggins, L. Adrienne Cupples, Annette L. Fitzpatrick, Megan L. Grove, Nicholas B. Larson, Nuzulul Kurniansyah
AimsWe tested the hypothesis that mitochondrial DNA copy number (CN) is associated with cardiometabolic disease (CMD) traits.Methods and resultsWe determined the cross-sectional association of mtDNA CN measured in whole blood with several CMD traits
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea6130f26506c5a026243298ce235064
https://doi.org/10.1101/2020.04.20.20016337
https://doi.org/10.1101/2020.04.20.20016337