Zobrazeno 61 - 70
of 156
pro vyhledávání: '"Dai Hirata"'
GSK-3 kinase Mck1 and calcineurin coordinately mediate Hsl1 down-regulation by Ca2+ in budding yeast
Publikováno v:
The EMBO Journal. 20:1074-1085
The Ca2+-activated pathways of Saccharomyces cerevisiae induce a delay in the onset of mitosis through the activation of Swe1, a negative regulatory kinase that inhibits the Cdc28-Clb complex. Calcineurin and Mpk1 activate Swe1 at the transcriptional
Autor:
Toshinaga Yamaguchi, Dai Hirata, Tetsuya Koyama, Masaki Mizunuma, Kazunori Kume, Atsunori Shitamukai, Tadamasa Komaruyama, Ryohei Tsubakiyama, Takafumi Ogawa
Publikováno v:
Bioscience, biotechnology, and biochemistry. 77(10)
Hog1 of Saccharomyces cerevisiae is activated by hyperosmotic stress, and this leads to cell-cycle delay in G1, but the mechanism by which cells restart from G1 delay remains elusive. We found that Whi3, a negative regulator of G1 cyclin, counteracte
Publikováno v:
FEBS Letters. 486:305-309
To investigate the mechanism coupling growth (protein synthesis) with cell division, we examined the relationship between the tyrosine kinase Wee1 that inhibits Cdc2-Cdc13 mitosis-inducing kinase by phosphorylating it, and protein synthesis inhibitio
Autor:
Kazuhito Sato, Mikiko Fukui, Ritsuko Arai, Dai Hirata, Issei Mabuchi, Yuki Sogabe, Masako Suda, Tokichi Miyakawa, Akeshi Morimatsu, Fumio Motegi
Publikováno v:
Genes to Cells. 4:517-527
Background Elongation factor 1α (EF1α), an essential component of the eukaryotic translational machinery, has been shown to possess various biochemical and biological activities, including F-actin-binding and -bundling, microtubule- severing, and t
Publikováno v:
Molecular Biology of the Cell. 10:2987-3001
We describe the isolation of fission yeast homologues of tubulin-folding cofactors B (Alp11) and E (Alp21), which are essential for cell viability and the maintenance of microtubules. Alp11Bcontains the glycine-rich motif (the CLIP-170 domain) involv
Autor:
Dai Hirata
Publikováno v:
Journal of the agricultural chemical society of Japan. 73:887-892
Publikováno v:
The Journal of Cell Biology
Digital.CSIC. Repositorio Institucional del CSIC
instname
Digital.CSIC. Repositorio Institucional del CSIC
instname
et al.
In fission yeast protein kinase C homologues (Pck1 and Pck2) are essential for cell morphogenesis. We have isolated mok1+ in a genetic screen to identify downstream effectors for Pck1/2. mok1+ is essential for viability and encodes a prot
In fission yeast protein kinase C homologues (Pck1 and Pck2) are essential for cell morphogenesis. We have isolated mok1+ in a genetic screen to identify downstream effectors for Pck1/2. mok1+ is essential for viability and encodes a prot
Publikováno v:
Bioscience, Biotechnology, and Biochemistry. 63:1871-1881
To identify new proteins involved in Mn2+ homeostasis, we isolated Mn(2+)-resistant mutants of Saccharomyces cerevisiae starting from a calcineurin-deficient, Mn2+ hypersensitive strain (delta cmp1 delta cmp2). The mutations were found to lie in the
Publikováno v:
Molecular Microbiology. 29:1307-1315
We have cloned and characterized a Saccharomyces cerevisiae gene YRR1 that is important for resistance to the mutagen 4-nitroquinoline N-oxide (4-NQO). The wild-type YRR1 gene encodes a protein that contains a Zn(II)2Cys6-type zinc-finger motif. Disr
Publikováno v:
Bioscience, Biotechnology, and Biochemistry. 71:615-617
In fission yeast, the conserved proteins, MO25/Pmo25, GC kinase/Nak1, Furry/Mor2, NDR kinase/Orb6, and Mob2, constitute the morphogenesis Orb6 network (MOR). Previously we showed that Pmo25 functions as an upstream component of MOR and that it plays