Zobrazeno 41 - 50
of 148
pro vyhledávání: '"Cynthia D. Guy"'
Publikováno v:
American Journal of Gastroenterology. 114:S972-S973
Autor:
Sam E. Moussa, Rong Zhou, Juan P. Frias, Mustafa R. Bashir, Cynthia A. Moylan, Rebecca Taub, Stephen A. Harrison, Seth J. Baum, Cynthia D. Guy, Meena B. Bansal, Naim Alkhouri, Brent A. Neuschwander-Tetri
Publikováno v:
Lancet (London, England). 394(10213)
Non-alcoholic steatohepatitis (NASH) is characterised by hepatic steatosis, inflammation, hepatocellular injury, and progressive liver fibrosis. Resmetirom (MGL-3196) is a liver-directed, orally active, selective thyroid hormone receptor-β agonist d
Autor:
Yan Han, Shu-Bing Qian, Rui Xi, Anastasia Varanko, Yongning Xin, Xiaodong Li, Lishan Su, Preetish Kadur Lakshminarasimha Murthy, Cynthia D. Guy, Xiling Shen, Botao Liu, Nikolai Rakhilin, Zhuo Wang, Kuei Ling Tung, Ji Wan, Feng Li
Publikováno v:
PLoS ONE, Vol 14, Iss 1, p e0209179 (2019)
PLoS ONE
PLoS ONE
Certain organs are capable of containing the replication of various types of viruses. In the liver, infection of Hepatitis B virus (HBV), the etiological factor of Hepatitis B and hepatocellular carcinoma (HCC), often remains asymptomatic and leads t
Autor:
Deepti M. Reddi, Mustafa R. Bashir, Claire J. Detweiler, Cynthia D. Guy, Shannon J. McCall, Lauren M Allen, Julius M. Wilder, Diana M. Cardona
Publikováno v:
Journal of Clinical and Surgical Pathology. 1
IgG4-related disease was first defined in autoimmune pancreatitis but is known to affect other organs, including the biliary tree and liver. The aim of this study was to assess IgG4-positive plasma cells in a spectrum of chronic liver diseases.
Autor:
Stephen A. Harrison, Stephen J. Rossi, Lei Ling, Sandra Owers, Rajarshi Banerjee, Bryan Baxter, Mark J. Jaros, James F. Trotter, Cynthia D. Guy, Alex M. DePaoli, Mustafa R. Bashir, Angelo H. Paredes
Publikováno v:
Hepatology (Baltimore, Md.). 71(4)
NGM282, an engineered fibroblast growth factor 19 analogue, rapidly and significantly reduced liver fat content in a multicenter, randomized, double-blind, placebo-controlled study in patients with biopsy-confirmed nonalcoholic steatohepatitis (NASH)
Autor:
Ayako Suzuki, Cynthia D. Guy, Jagpal Singh Klair, Ju Dong Yang, Jeanne M. Clark, Katherine P. Yates, Anna Mae Diehl, Ryan M. Gill, Aynur Unalp-Arida, Manal F. Abdelmalek, Joel E. Lavine
Publikováno v:
Hepatology. 64:85-91
UNLABELLED Postmenopausal women with nonalcoholic steatohepatitis are at an increased risk of hepatic fibrosis compared with premenopausal women. Whether duration of estrogen deficiency in postmenopausal state dictates an individual's fibrosis risk r
Autor:
Cynthia D. Guy, Lixin Zhu, Ruixin Zhu, Patrizia Farci, Wensheng Liu, Sugantha Govindarajan, Fausto Zamboni, Dingfeng Wu, Susan S. Baker, Zhiwei Cao, Anna Mae Diehl, Manal F. Abdelmalek, Cynthia A. Moylan, Robert D. Baker, Weili Lin
Publikováno v:
The Journal of Pathology. 238:531-542
Obese animals and non-alcoholic fatty liver disease (NAFLD) patients exhibit elevated blood alcohol, suggesting potential contributions of alcohol metabolism to the development of NAFLD. Liver gene expression in patients with biopsy-proven mild (N =
Autor:
Matt Kanke, Rigney E. Turnham, Lola M. Reid, Timothy A. Dinh, Anna Mae Diehl, Cynthia D. Guy, Edward R. Kastenhuber, Adam B. Francisco, Raymond S. Yeung, John D. Scott, Scott W. Lowe, Eliane Wauthier, Praveen Sethupathy, Seona Lee, Mark L. Jewell, Ramja Sritharan
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 7, Iss 4, Pp 803-817 (2019)
Cellular and Molecular Gastroenterology and Hepatology, Vol 7, Iss 4, Pp 803-817 (2019)
Background & Aims: Fibrolamellar carcinoma (FLC) is a rare liver cancer that primarily affects adolescents and young adults. It is characterized by a heterozygous approximately 400-kb deletion on chromosome 19 that results in a unique fusion between
Autor:
Guido Ferrari, Audrey Lan, Marzena Swiderska-Syn, Susanna Naggie, Anna Mae Diehl, Sam Lusk, Wing-Kin Syn, Cynthia D. Guy, Steve S. Choi
Publikováno v:
Open Forum Infectious Diseases
Liver disease is a leading cause of HIV-related mortality. Hepatitis C virus (HCV)–related fibrogenesis is accelerated in the setting of HIV coinfection, yet the mechanisms underlying this aggressive pathogenesis are unclear. We identified formalin
Autor:
Michael H, Schild, Cynthia D, Guy
Publikováno v:
Surgical pathology clinics. 11(2)
Nonalcoholic fatty liver disease (NAFLD) is a major health concern and the prevalence continues to increase in many industrialized and developing countries around the world. NAFLD affects adults and children. NAFLD-related cirrhosis is expected to be