Zobrazeno 31 - 40
of 148
pro vyhledávání: '"Cynthia D. Guy"'
Autor:
Ying Wang, Cynthia D. Guy, Cynthia A. Moylan, Anna Mae Diehl, Catherine F. Howe, Manal F. Abdelmalek, Ricardo Henao, Kara Wegermann
Publikováno v:
Hepatology Communications
Hepatology Communications, Vol 5, Iss 4, Pp 608-617 (2021)
Hepatology Communications, Vol 5, Iss 4, Pp 608-617 (2021)
Identifying patients at higher risk for poor outcomes from nonalcoholic fatty liver disease (NAFLD) remains challenging. Metabolomics, the comprehensive measurement of small molecules in biological samples, has the potential to reveal novel noninvasi
Autor:
Ying Wang, Anna Mae Diehl, Ricardo Henao, Manal F. Abdelmalek, Keri A. Seymour, Ranjan Sudan, Matthew J Crowley, Cynthia D. Guy, Anastasia-Stefania Alexopoulos, Dana Portenier, Andrea D. Coviello
Publikováno v:
Diabetes. 69
T2DM increases risk for advanced fibrosis in NAFLD, however little is known about the impact of glycemic control on fibrosis severity. Objective: To assess whether glycemic control is associated with severity of fibrosis in NAFLD. Methods: We utilize
Autor:
Kristin Nelson, Hsiao D. Lieu, Mildred Gottwald, James F. Trotter, Guy W. Neff, Nadege Gunn, Alex M. DePaoli, Sam E. Moussa, Ziad Younes, Andrew Yan, Mustafa R. Bashir, Angelo H. Paredes, Juan P. Frias, William C.G. Chang, Cynthia D. Guy, Stephen A. Harrison, Lei Ling, Anita Kohli
Publikováno v:
Gastroenterology. 160(1)
Background & Aims Aldafermin, an engineered analog of fibroblast growth factor 19, inhibits bile acid synthesis and regulates metabolic homeostasis. We report results from a 24-week, phase 2 study, with serial liver biopsies, of patients with nonalco
Autor:
Michael Torbenson, Cynthia D. Guy, Robert A. Anders, Saba Yasir, Sudhakar K. Venkatesh, Zongming Eric Chen, Hee Eun Lee, Tsung Teh Wu
Publikováno v:
Hum Pathol
Summary Cases of new pseudotumors of the liver were collected from multiple medical centers. Four resection and 4 biopsy specimens were collected, including 4 women and 4 men at an average age of 48 ± 15 years (range: 28–73 years). The lesions wer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5d8aa91da7c2f834a02c59b8cf96047
https://europepmc.org/articles/PMC9469469/
https://europepmc.org/articles/PMC9469469/
Autor:
Jason Gibson, David S. Hsu, Jeongeun Hyun, Anna Mae Diehl, Simon G. Gregory, Richard T. Premont, Cynthia D. Guy, Mark L. Jewell, Kuo Du, Seh-Hoon Oh, Thomas J. Ribar
Publikováno v:
Am J Pathol
Fibrolamellar carcinoma (FLC) is characterized by in-frame fusion of DnaJ heat shock protein family (Hsp40) member B1 (DNAJB1) with protein kinase cAMP-activated catalytic subunit α (PRKACA) and by dense desmoplasia. Surgery is the only effective tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db7b8fb52946e0d6a93a78c380043659
https://europepmc.org/articles/PMC10069284/
https://europepmc.org/articles/PMC10069284/
Autor:
Margery A. Connelly, Srinivasan Dasarathy, Rohit Loomba, Raj Vuppalanchi, Naga Chalasani, Brent A. Neuschwander-Tetri, Cynthia D. Guy, Mohammad S. Siddiqui, Arun J. Sanyal, James Tonascia, Mark L. Van Natta, Julia Wattacheril
Publikováno v:
J Hepatol
Obeticholic acid (OCA), a farnesoid X receptor agonist, increases total and low-density lipoprotein cholesterol (LDL-C) in patients with non-alcoholic steatohepatitis. In the present study, we aimed to evaluate the impact of OCA therapy on lipoprotei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d0ae72035a3fb7f42901ce5d6f35a9b
https://europepmc.org/articles/PMC6920569/
https://europepmc.org/articles/PMC6920569/
Autor:
Elizabeth M. Brunt, Ryan M. Gill, Norah A. Terrault, Patricia Belt, Anna Mae Diehl, Brent A. Neuschwander-Tetri, Srinivasan Dasarathy, Oscar W. Cummings, Matthew M. Yeh, Cynthia Behling, Kris V. Kowdley, Cynthia D. Guy, Arun J. Sanyal, James Tonascia, Laura Wilson, David E. Kleiner, Melissa J. Contos, Rohit Loomba, Naga Chalasani, Joel E. Lavine
Publikováno v:
JAMA Network Open
Key Points Question In patients with nonalcoholic fatty liver disease who are not undergoing specific therapeutic interventions, what factors are associated with progression and regression of hepatic fibrosis? Findings In this cohort study of 446 pat
Autor:
Cynthia D. Guy, Michael H Schild
Publikováno v:
Surgical Pathology Clinics. 11:267-285
Nonalcoholic fatty liver disease (NAFLD) is a major health concern and the prevalence continues to increase in many industrialized and developing countries around the world. NAFLD affects adults and children. NAFLD-related cirrhosis is expected to be
Autor:
Cynthia D. Guy, Claire Faulkner, Manal F. Abdelmalek, Larry Mimms, Ranjan Sudan, Anna Mae Diehl, Anjali Jain, Xiao-jun Li, Lauren Okada, Dana Portenier, S Singh, Lisa Richards, Rohit Loomba, Kelly D. Hester
Publikováno v:
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, vol 17, iss 9
Background & Aims We analyzed markers of fibrosis in serum samples from patients with nonalcoholic fatty liver disease (NAFLD), assessed by liver biopsy. We used serum levels of markers to develop an algorithm to discriminate patients with advanced f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b31f3804628ef5863ad3bbb749e54907
https://escholarship.org/uc/item/0b04137v
https://escholarship.org/uc/item/0b04137v
Autor:
Shannon J. McCall, Cynthia D. Guy, Diana M. Cardona, Amanda Hemmerich, Xuefeng Zhang, Grant Harrison, Kathryn Perkinson, Debra Fleming
Publikováno v:
American Journal of Clinical Pathology. 149:67-75
Objectives To characterize the expression of SOX11 and TFE3 proteins in solid-pseudopapillary neoplasms (SPNs) and their histologic mimickers. Methods Immunohistochemistry for SOX11, TFE3, and β-catenin was performed on 31 cases of surgically resect