Zobrazeno 21 - 30
of 147
pro vyhledávání: '"Cynthia D. Guy"'
Sex and Menopause Modify the Effect of Single Nucleotide Polymorphism Genotypes on Fibrosis in NAFLD
Autor:
Jiayin Zheng, Anna Mae Diehl, Cynthia D. Guy, Ayako Suzuki, Kara Wegermann, Allison E. Ashley-Koch, Shein-Chung Chow, Andrea D. Coviello, Melanie E. Garrett, Cynthia A. Moylan, Manal F. Abdelmalek
Publikováno v:
Hepatology Communications, Vol 5, Iss 4, Pp 598-607 (2021)
Hepatology Communications
Hepatology Communications
The development of fibrosis in nonalcoholic fatty liver disease (NAFLD) is influenced by genetics, sex, and menopausal status, but whether genetic susceptibility to fibrosis is influenced by sex and reproductive status is unclear. Our aim was to iden
Autor:
Mathew M. Yeh, Cynthia D. Guy, Patricia Belt, Ryan M. Gill, Danielle Carpenter, Oscar W. Cummings, Laura A. Wilson, Daniela S. Allende, David E. Kleiner, Cynthia Behling, Samer Gawrieh, Mark L. Van Natta, Naga Chalasani
Publikováno v:
Liver International
Background/Aims Glycogen synthesis and storage are normal hepatocyte functions. However, glycogenosis, defined as excess hepatocyte glycogen visible by routine H&E light microscopy, has not been well characterized in nonalcoholic fatty liver disease
Autor:
Lei Zhao, Shu-Yuan Xiao, Diana M. Cardona, Cynthia D. Guy, Xuefeng Zhang, Liyan Xu, N. Lynn Ferguson, Maria Westerhoff, Amanda Hemmerich, John Hart, Cynthia L. Green, Beiyu Liu, Shannon J. McCall, Rish K. Pai
Publikováno v:
Virchows Archiv. 478:427-434
The diagnosis of invasive adenocarcinoma of the gallbladder can sometimes be challenging. The presence of true desmoplastic reaction facilitates the diagnosis of invasion. However, desmoplasia-like changes can be observed in benign gallbladder condit
Autor:
Stephen A Harrison, Manal F Abdelmalek, Guy Neff, Nadege Gunn, Cynthia D Guy, Naim Alkhouri, Mustafa R Bashir, Bradley Freilich, Anita Kohli, Arun Khazanchi, Muhammad Y Sheikh, Mark Leibowitz, Mary E Rinella, Mohammad S Siddiqui, Mark Kipnes, Sam E Moussa, Ziad H Younes, Meena Bansal, Seth J Baum, Brian Borg, Peter J Ruane, Paul J Thuluvath, Mildred Gottwald, Mujib Khan, Charles Chen, Liza Melchor-Khan, William Chang, Alex M DePaoli, Lei Ling, Hsiao D Lieu
Publikováno v:
The lancet. Gastroenterologyhepatology. 7(7)
Non-alcoholic steatohepatitis (NASH) is characterised by hepatic steatosis, inflammation, and injury, and is associated with an increased risk of liver transplantation and death. NASH affects more than 16 million people in the USA, and there is no ap
Autor:
Kyle Decker, Tsung-Yuan Tsai, Mustafa R. Bashir, Hongjiang Wei, Hien Nguyen, Chunlei Liu, Cynthia D. Guy, Steven Cao
Publikováno v:
Magnetic Resonance in Medicine. 83:1322-1330
Purpose To characterize the magnetic susceptibility changes of liver fibrosis using susceptibility tensor imaging. Methods Liver biopsy tissue samples of patients with liver fibrosis were obtained. Three-dimensional gradient-echo and diffusion-weight
Autor:
Anna Mae Diehl, Oliver Glass, Elizabeth Bechard, Jane F. Pendergast, Cynthia D. Guy, Daniel Liu, Manal F. Abdelmalek
Publikováno v:
Hepatology Communications
Hepatology Communications, Vol 6, Iss 2, Pp 334-344 (2022)
Hepatology Communications, Vol 6, Iss 2, Pp 334-344 (2022)
Exercise is a foundational treatment for nonalcoholic fatty liver disease (NAFLD); however, the majority of patients are unable to initiate and maintain effective exercise habits and remain at increased risk for progressive liver disease. Barriers an
Autor:
Cynthia D. Guy, Samuel J. Kesseli, M.G. Hartwig, Brian I. Shaw, Nader Abraham, Dimitrios Moris, Mingqing Song, Andrew S. Barbas, Stuart J. Knechtle, Robin Schmitz, Min Zhang, Zachary W. Fitch, Greta N. Cywinska, Jared N. Gloria, Samantha E. Halpern
Publikováno v:
Hepatology Communications
Hepatology Communications, Vol 5, Iss 9, Pp 1527-1542 (2021)
Hepatology Communications, Vol 5, Iss 9, Pp 1527-1542 (2021)
Normothermic machine perfusion (NMP) provides clinicians an opportunity to assess marginal livers before transplantation. However, objective criteria and point-of-care (POC) biomarkers to predict risk and guide decision making are lacking. In this in
Autor:
Cynthia D. Guy, Ying Wang, Anna Mae Diehl, Dana Portenier, Dawn Piercy, Matthew J Crowley, Andrea D. Coviello, Anastasia-Stefania Alexopoulos, Ranjan Sudan, Cynthia A. Moylan, Manal F. Abdelmalek, Keri A. Seymour, Ricardo Henao
Publikováno v:
Hepatology (Baltimore, Md.). 74(3)
BACKGROUND AND AIMS Whether glycemic control, as opposed to diabetes status, is associated with the severity of NAFLD is open for study. We aimed to evaluate whether degree of glycemic control in the years preceding liver biopsy predicts the histolog
Autor:
Wing-Kin Syn, Keyur Patel, Cynthia D. Guy, Anna Mae Diehl, Robert D. Streilein, Ricardo Henao, Oliver Glass, Hans J Gruss, Manal F. Abdelmalek, Cynthia A. Moylan, Russell P. Hall
Publikováno v:
Hepatology Communications
Hepatology Communications, Vol 2, Iss 11, Pp 1344-1355 (2018)
Hepatology Communications, Vol 2, Iss 11, Pp 1344-1355 (2018)
The severity of hepatic fibrosis is the primary predictor of liver‐related morbidity and mortality in patients with nonalcoholic fatty liver disease (NAFLD). Unfortunately, noninvasive serum biomarkers for NAFLD‐associated fibrosis are limited. W
Autor:
Clemence M, Canivet, Norma, David, Helene, Pailhoriès, Martial, Briand, Cynthia D, Guy, Olivier, Bouchez, Gilles, Hunault, Lionel, Fizanne, Adrien, Lannes, Frederic, Oberti, Isabelle, Fouchard, Paul, Calès, Anna Mae, Diehl, Matthieu, Barret, Jerome, Boursier
Publikováno v:
Alimentary pharmacologytherapeuticsREFERENCES. 53(6)
The reconstruction of metagenome-assembled genomes (MAGs) has emerged as a powerful approach for combining the taxonomic and functional content of microbial populations.To use this new approach to highlight mechanisms linking gut microbiota to NAFLD