Zobrazeno 21 - 30
of 33
pro vyhledávání: '"Craig Blanchette"'
Autor:
Helen Booler, Justin Scheer, Craig Blanchette, Nikhil Peer, Whitney Shatz, Amrita V. Kamath, Susan Crowell, Wendy Sandoval, Philip E. Hass, Kelly M. Loyet, Maciej Paluch, Guanghui Han, Robert F. Kelley, Vladimir Bantseev, Ashley Morando
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 6, p e0218613 (2019)
PLoS ONE, Vol 14, Iss 6, p e0218613 (2019)
Innovative protein engineering and chemical conjugation technologies have yielded an impressive number of drug candidates in clinical development including >80 antibody drug conjugates, >60 bispecific antibodies, >35 Fc-fusion proteins and >10 immuno
Autor:
Maria Mouchess, Eric Suto, Sara Chan, Bingbing Dai, Christine Tam, Yi Cao, Martine Darwish, Dongping He, Susan Haller, Jeffrey Eastham-Anderson, Yvonne Franke, Craig Blanchette, Wyne Lee, Cary Austin, Robert Lazarus, Tangsheng Yi
Publikováno v:
The Journal of Immunology. 202:132.4-132.4
Loss of B cell tolerance and generation of autoreactive anti-nuclear antibodies are hallmarks of systemic lupus erythematosus and lupus nephritis. The mechanism of anti-nuclear immunoglobulin accumulation and clearance in lupus nephritis pathogenesis
Publikováno v:
The Journal of Immunology. 200:120.26-120.26
MHC proteins that present peptide ligands to T cells form nano-scale clusters on the cell membrane of antigen-presenting cells. While MHC clustering is thought to influence antigen presentation to T cells and may depend on cell type and pathophysiolo
Autor:
M. Grant Albrecht, Craig Blanchette
Publikováno v:
Journal of The Electrochemical Society. 145:4019-4025
Fourier transform infrared spectroscopy and X-ray photoelectron spectroscopy were used to monitor the chemical composition of both ladder and cage hydrogen silsesquioxane (HSQ) as a function of bake and cure temperature in the range 150-425°C. Three
Autor:
Wei, He, Juntao, Luo, Feliza, Bourguet, Li, Xing, Sun K, Yi, Tingjuan, Gao, Craig, Blanchette, Paul T, Henderson, Edward, Kuhn, Mike, Malfatti, William J, Murphy, R Holland, Cheng, Kit S, Lam, Matthew A, Coleman
Publikováno v:
Protein science : a publication of the Protein Society. 22(8)
Nanolipoprotein particles (NLPs) are nanometer-scale discoidal particles that feature a phospholipid bilayer confined within an apolipoprotein “scaffold,” which are useful for solubilizing hydrophobic molecules such as drugs and membrane proteins
Autor:
Dina R Weilhammer, Alexis D Dunkle, Craig Blanchette, Tyler Boone, Sean Gilmore, Michele Corzett, Nicholas Fischer, Doerte Lehmann, Cheri Lychak, Paul Hoeprich, Adam Driks, Amy Rasley
Publikováno v:
The Journal of Immunology. 196:145.3-145.3
There is considerable interest in developing a novel Bacillus anthracis vaccine that improves upon the shortcomings of the licensed vaccine for broader, more rapid protection of the population. Ideally, a vaccine would recognize the spore in addition
Publikováno v:
The Journal of Immunology. 194:113.17-113.17
T cell programming into distinct T cell subsets depends in a large extent from the quality and quantity of the signal delivered to T cells by professional antigen presenting cells (APC). However, it is difficult to vary parameters of T cell stimulati
Autor:
Alexis Dunkle, Craig Blanchette, Tyler Boone, Michele Corzett, Mona Hwang, Nicholas Fischer, Doerte Lehmann, Cheri Lychak, Paul Hoeprich, Adam Driks, Amy Rasley
Publikováno v:
The Journal of Immunology. 192:141.1-141.1
Subunit vaccines are theoretically safe and easy to manufacture but require effective adjuvants and delivery systems to yield protective immunity, particularly at critical mucosal sites such as the lung. We investigated nanolipoprotein particles (NLP
Autor:
Dina Weilhammer, Shabnam Alam, Craig Blanchette, Nicholas Fischer, Gabriela Loots, Michele Corzett, Cindy Thomas, Mona Hwang, Cheri Lychak, Andrea Sant, Amy Rasley
Publikováno v:
The Journal of Immunology. 190:48.19-48.19
Therapies targeting the innate immune system have the potential to provide transient, non-specific protection from a variety of infectious organisms. As such, we have employed a nanolipoprotein (NLP) platform to enhance the efficacy of synthetic inna
Autor:
Dina Weilhammer, Craig Blanchette, Nicholas Fischer, Sahar El-Etr, Gabriela Loots, Michele Corzett, Mona Hwang, Cindy Thomas, Cheri Lychak, Sanaz Mohammadi, Amy Rasley
Publikováno v:
The Journal of Immunology. 188:53.12-53.12
Modulation of the innate immune system has the potential to provide transient, non-specific protection from a variety of infectious organisms. Activation of innate immunity is rapid and short-lived, therefore methods aimed at enhancing and prolonging