Zobrazeno 81 - 86
of 86
pro vyhledávání: '"Colm O'Dushlaine"'
Autor:
Elaine Kenny, Benjamin M. Neale, Derek W. Morris, Philip Asherson, Michael Gill, Jessica Lasky-Su, Richard Anney, Colm O'Dushlaine, Stephen V. Faraone, Barbara Franke
The considerable data-handling requirements for genome wide association studies (GWAS) prohibit individual calling of genotypes and create a reliance on sophisticated "genotype-calling algorithms." Despite their obvious utility, the current genotypin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f69cc59cc301f9e230452ca360bd8932
https://europepmc.org/articles/PMC2921075/
https://europepmc.org/articles/PMC2921075/
Autor:
David St Clair, Frank A. Middleton, Peter M. Visscher, Kevin A. McGhee, John L. Waddington, Helena Medeiros, Joshua M. Korn, Vihra Milanova, Gillian Fraser, Stuart MacGregor, David Curtis, Nadine Norton, Nicholas Bass, Ivan Nikolov, Scott Mahon, Jennifer Stone, Kimberly Chambert, Casey Gates, Alan W Maclean, Christopher P. Morley, Margaret Van Beck, Ayman H. Fanous, James A. Knowles, Draga Toncheva, P. Malloy, Jacob Lawrence, Célia Barreto Carvalho, Shaun Purcell, Christina M. Hultman, George Kirov, Digby Quested, Soh Leh Kwan, Carlos N. Pato, Elaine Kenny, Hywel Williams, Vinay Puri, Aiden Corvin, Nicholas John Craddock, Michael Conlon O'Donovan, Nicholas Walker, Nigel Williams, Peter Holmans, Hugh Gurling, Colm O'Dushlaine, Mark J. Daly, Emma Flordal Thelander, Jonathan Pimm, David V. Conti, Michael Gill, Susmita Datta, Derek W. Morris, Douglas M. Ruderfer, Khalid Choudhury, Walter J. Muir, Stacey Gabriel, Ben S. Pickard, Kristen Ardlie, Srinivasa Thirumalai, Michael John Owen, Edward M. Scolnick, Caroline Crombie, Robert Krasucki, M. Helena Azevedo, Michele T. Pato, Steve McCarroll, António Macedo, Lucy Georgieva, Douglas Blackwood, Patrick F. Sullivan, Pamela Sklar, Paul Lichtenstein, Andrew McQuillin, Patrick Sullivan, Carlos Ferreira
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Agência para a Sociedade do Conhecimento (UMIC)-FCT-Sociedade da Informação
instacron:RCAAP
Agência para a Sociedade do Conhecimento (UMIC)-FCT-Sociedade da Informação
instacron:RCAAP
Schizophrenia is a severe mental disorder marked by hallucinations, delusions, cognitive deficits and apathy, with a heritability estimated at 73–90% (ref. 1). Inheritance patterns are complex, and the number and type of genetic variants involved a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d81ac4724713772ad334389c90dafed1
https://europepmc.org/articles/PMC3912847/
https://europepmc.org/articles/PMC3912847/
Autor:
Herbert Roeyers, Colm O'Dushlaine, Edmund J.S. Sonuga-Barke, Richard P. Ebstein, Ana Miranda, Aribert Rothenberger, Philip Asherson, Jessica Lasky-Su, Tobias Banaschewski, Stephen V. Faraone, Wai Chen, Fernando Mulas, Aisling Mulligan, Joseph A. Sergeant, Jan K. Buitelaar, Barbara Franke, Elaine Kenny, Benjamin M. Neale, Robert D. Oades, Kaixin Zhou, H. C. Steinhausen, Richard Anney, Michael Gill, Hanna Christiansen, Alejandro Arias-Vásquez
Publikováno v:
American Journal of Medical Genetics. Part B : Neuropsychiatric Genetics, 147B, 8, pp. 1369-78
American Journal of Medical Genetics. Part B : Neuropsychiatric Genetics, 147B, 1369-78
American Journal of Medical Genetics. Part B : Neuropsychiatric Genetics, 147B, 1369-78
Contains fulltext : 71374.pdf (Publisher’s version ) (Closed access) Attention-deficit/hyperactivity disorder (ADHD) is typically characterized by inattention, excessive motor activity, impulsivity, and distractibility. Individuals with ADHD have s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d06ff2a000ecf0eff6674dff6714f6a6
https://doi.org/10.1002/ajmg.b.30871
https://doi.org/10.1002/ajmg.b.30871
Autor:
Michael E. Weale, Rachel A. Gibson, Gianpiero L. Cavalleri, Reetta Kälviäinen, Colm O'Dushlaine, Norman Delanty, Michael Gill, Ciara Dolan, David T. Croke, Derek W. Morris, Alice Stanton, David A. Hosford, Sanjay M. Sisodiya, Kai Eriksson, Anne-Mari Kantanen, Aiden Corvin
PUBLISHED
The recent completion of the International HapMap Project has rapidly advanced our understanding of linkage disequilibrium (LD) in the human genome. Today, tagging SNPs (tSNPs) can be quickly and easily selected and consequently HapMap
The recent completion of the International HapMap Project has rapidly advanced our understanding of linkage disequilibrium (LD) in the human genome. Today, tagging SNPs (tSNPs) can be quickly and easily selected and consequently HapMap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a4fb7a0c3deb88303f4859ba8efecf9
Autor:
Jordan W. Smoller, Andrew W. Kirby, Phil Lee, Colm O'Dushlaine, Laramie E. Duncan, Bruce M. Cohen, Dost Öngür, Peter Holmans
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 2, p e89441 (2014)
PLoS ONE, Vol 9, Iss 2, p e89441 (2014)
Background The quest to understand the neurobiology of schizophrenia and bipolar disorder is ongoing with multiple lines of evidence indicating abnormalities of glia, mitochondria, and glutamate in both disorders. Despite high heritability estimates
Autor:
Elizabeth A. Heron, Ricardo Segurado, Aiden Corvin, Colm O'Dushlaine, Elaine Kenny, Michael Gill, Derek W. Morris
Publikováno v:
Bioinformatics. 25:2762-2763
Summary: We present a tool that assesses the enrichment of significant associations from genome-wide association studies (GWAS) in a pathway context. The SNP ratio test (SRT) compares the proportion of significant to all SNPs within genes that are pa