Zobrazeno 51 - 60
of 115
pro vyhledávání: '"Christoph Kellendonk"'
Autor:
Atheir I. Abbas, Joshua A. Gordon, Caroline Rauffenbart, Scott S. Bolkan, Christoph Kellendonk, Joseph M. Stujenske, Sébastien Parnaudeau, Alexander Z. Harris, Timothy Spellman
Publikováno v:
Nature Neuroscience
Nature Neuroscience, Nature Publishing Group, 2017, advance online publication, pp.987-996. ⟨10.1038/nn.4568⟩
Nature neuroscience
Nature Neuroscience, 2017, 20, pp.987-996. ⟨10.1038/nn.4568⟩
Nature Neuroscience, Nature Publishing Group, 2017, 20 (7), pp.987-996. ⟨10.1038/nn.4568⟩
Nature Neuroscience, Nature Publishing Group, 2017, advance online publication, pp.987-996. ⟨10.1038/nn.4568⟩
Nature neuroscience
Nature Neuroscience, 2017, 20, pp.987-996. ⟨10.1038/nn.4568⟩
Nature Neuroscience, Nature Publishing Group, 2017, 20 (7), pp.987-996. ⟨10.1038/nn.4568⟩
International audience; The mediodorsal thalamus (MD) shares reciprocal connectivity with the prefrontal cortex (PFC), and decreased MD–PFC connectivity is observed in schizophrenia patients. Patients also display cognitive deficits including impai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acf6994122690578426be679e74a1627
https://hal.archives-ouvertes.fr/hal-01544138
https://hal.archives-ouvertes.fr/hal-01544138
Autor:
Alex Dranovsky, Bruno P. Guiard, Alain M. Gardier, Sarah E. Canetta, Qingyuan Meng, E. David Leonardo, Alvaro L. Garcia-Garcia, Christoph Kellendonk
Publikováno v:
Cell Reports, Vol 18, Iss 5, Pp 1144-1156 (2017)
Lifelong homeostatic setpoints for mood-related behaviors emerge during adolescence. Serotonin (5-HT) plays an important role in refining the formation of brain circuits during sensitive developmental periods. In rodents, the role of 5-HT1A receptors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70598c4131183faa5c7ad9cf2934dd3f
https://europepmc.org/articles/PMC5325088/
https://europepmc.org/articles/PMC5325088/
Autor:
Paul E. M. Phillips, Gaël Malleret, Vanessa Winiger, Scott Ng-Evans, Julia Morud, Mary Elizabeth Bach, H. Jonathan Polan, Eleanor H. Simpson, Dominik Biezonski, Christoph Kellendonk, Judy P. Zhu, Eric R. Kandel
Publikováno v:
Learning & Memory. 21:205-214
A common genetic polymorphism that results in increased activity of the dopamine regulating enzyme COMT (the COMT Val158 allele) has been found to associate with poorer cognitive performance and increased susceptibility to develop psychiatric disorde
Autor:
Maxime Cazorla, Susanne E. Ahmari, Holly Moore, Muhammad Omar Chohan, Christoph Kellendonk, Mariya Shegda, Fernanda Delmondes de Carvalho, Nao Chuhma, Stephen Rayport
Publikováno v:
Neuron
Neuron, Elsevier, 2014, 81 (1), pp.153-64. ⟨10.1016/j.neuron.2013.10.041⟩
Neuron, Elsevier, 2014, 81 (1), pp.153-64. ⟨10.1016/j.neuron.2013.10.041⟩
International audience; Structural plasticity in the adult brain is essential for adaptive behavior. We have found a remarkable anatomical plasticity in the basal ganglia of adult mice that is regulated by dopamine D2 receptors (D2Rs). By modulating
Autor:
Anissa Abi-Dargham, Roberto Gil, Christoph Kellendonk, Jared X. Van Snellenberg, Guillermo Horga
Publikováno v:
Schizophrenia Bulletin
Background Recent work with a dopamine 2 receptor (D2R) over-expressing (D2R-OE) mouse has suggested that this receptor over-expression leads to a highly plastic increase in bridging collaterals from the associative striatum (AST) to the external seg
Autor:
Denise Sorisio, Alain J. De Solis, Robin Freyberg, Travis J Morgenstern, Prashant Donthamsetti, David R. Sibley, Paul L. Harris, Zachary J. Farino, Despoina Aslanoglou, Eugene V. Mosharov, Zachary Freyberg, Holly Moore, Benjamin P. Inbar, R. Benjamin Free, Antonella Maffei, Gary E. Schwartz, Matthias Quick, Pattama Wiriyasermkul, Claudia Schmauss, Lori M. Zeltser, Christoph Kellendonk, Jonathan A. Javitch
Publikováno v:
Biological Psychiatry. 85:S21
Publikováno v:
Schizophrenia Bulletin. 38:1111-1117
The negative symptoms of schizophrenia include deficits in motivation, for which there is currently no treatment available. Animal models provide a powerful tool for identifying the potential pathophysiological mechanisms underlying the motivation de
The dopamine hypothesis of schizophrenia is supported by a large number of imaging studies that have identified an increase in dopamine binding at the D2 receptor selectively in the striatum. Here we review a decade of work using a regionally restric
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da1a5c744a9423b317b00e0afb43dfd9
https://europepmc.org/articles/PMC5121031/
https://europepmc.org/articles/PMC5121031/
Autor:
J A Gordon, LouJin Song, Neil L. Harrison, Scott S. Bolkan, Christoph Kellendonk, Nancy Padilla-Coreano, Sarah Canetta, R Sahn, Alan S. Brown
Publikováno v:
Molecular psychiatry. 21(7)
Autor:
Christoph Kellendonk, Mazen A. Kheirbek, Jozsef Meszaros, Lindsay Kenney, Peter D. Balsam, Matthew R. Bailey, Eva Holzner, Fernanda Carvalho Poyraz
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience, vol 36, iss 22
Altered dopamine D2 receptor (D2R) binding in the striatum has been associated with abnormal motivation in neuropsychiatric disorders, including schizophrenia. Here, we tested whether motivational deficits observed in mice with upregulated D2Rs (D2R-