Zobrazeno 31 - 40
of 119
pro vyhledávání: '"Christian Gaiddon"'
Publikováno v:
Chemical Society Reviews
Chemical Society Reviews, Royal Society of Chemistry, 2020, 49 (19), pp.6995-7014. ⟨10.1039/d0cs00163e⟩
Chemical Society Reviews, Royal Society of Chemistry, 2020, 49 (19), pp.6995-7014. ⟨10.1039/d0cs00163e⟩
Referred to as the "guardian of the genome", p53 is the most frequently mutated protein in cancer and almost all cancers exhibit malfunction along the p53 pathway. As an overexpressed and tumour-specific target, the past two decades have seen conside
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1465d5c1fbe3739058ca322a04f483f3
https://hal.inria.fr/hal-03044534
https://hal.inria.fr/hal-03044534
How to Prevent Sarcopenia Occurrence during Neoadjuvant Chemotherapy for Oesogastric Adenocarcinoma?
Autor:
Benoit Romain, Cécile Brigand, Aina Venkatasamy, Jean-Baptiste Delhorme, Marlène Voisinet, Christian Gaiddon, Serge Rohr, Hefzi Alratrout
Publikováno v:
Nutrition and Cancer
Nutrition and Cancer, Taylor & Francis (Routledge), 2020, pp.1-7. ⟨10.1080/01635581.2020.1770813⟩
Nutrition and Cancer, Taylor & Francis (Routledge), 2020, pp.1-7. ⟨10.1080/01635581.2020.1770813⟩
The aim of this study was to evaluate the impact of a preoperative feeding jejunostomy (FJ) on the occurrence of sarcopenia before and after preoperative chemotherapy for patients with an oesogastric adenocarcinoma (OGA). Forty-six patients with pote
Autor:
Aldo S. Estrada-Montaño, Alexandre Gries, Longzhu Q. Shen, Raymundo Marcial-Hernandez, Carolina Torres-Gutiérrez, José A. Oviedo-Fortino, Amira Grain-Hayton, Christian Gaiddon, Ronan Le Lagadec, Alexander D. Ryabov
Publikováno v:
Organometallics
Organometallics, American Chemical Society, 2020, 39 (10), pp.1842-1854. ⟨10.1021/acs.organomet.0c00107⟩
Organometallics, American Chemical Society, 2020, 39 (10), pp.1842-1854. ⟨10.1021/acs.organomet.0c00107⟩
Bis-cyclometalated iron(II) complex [Fe(κC,N-phpy)2(CO)2] (1) (phpyH = 2-phenylpyridine) has been prepared in good yield from [Fe(CO)5] and [Hg(phpy)2] in the presence of dibromine, which is unexpe...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ed145fc0475b50f631f4d905453c50d
https://hal.inria.fr/hal-03044551
https://hal.inria.fr/hal-03044551
Autor:
Christian Gaiddon, Isabelle Gross, Emilie Bersuder, Aurélien de Reyniès, Isabelle Hinkel, Marine Beck, Laetitia Marisa, Jean-Noël Freund, Ahlam Moufok-Sadoun, Isabelle Duluc, Elisabeth Martin, Georg Mellitzer, Mathilde Baranger
Publikováno v:
Oncogene
Oncogene, Nature Publishing Group, In press, ⟨10.1038/s41388-020-01546-y⟩
Oncogene, Nature Publishing Group, In press, ⟨10.1038/s41388-020-01546-y⟩
Cadherins form a large and pleiotropic superfamily of membranous proteins sharing Ca2+-binding repeats. While the importance of classic cadherins such as E- or N-cadherin for tumorigenesis is acknowledged, there is much less information about other c
Autor:
Jean-Noël Freund, Christian Gaiddon, Priscila da Silva Figueiredo Celestino Gomes, Gilles Riegel, Ronan Le Lagadec, Jean-Baptiste Delhorme, Catherine Tomasetto, Cynthia Licona, Ricardo Cerón-Camacho, Michel Pfeffer, Vania Vidimar, Georg Mellitzer, Isabelle Gross, Bastien Boff, Aina Venkatasamy, Didier Rognan
Publikováno v:
Inorganic Chemistry Frontiers
Inorganic Chemistry Frontiers, Royal Society of Chemistry, 2020, 7 (3), pp.678-688. ⟨10.1039/C9QI01148J⟩
Inorganic Chemistry Frontiers, Royal Society of Chemistry, 2020, 7 (3), pp.678-688. ⟨10.1039/c9qi01148j⟩
Inorganic Chemistry Frontiers, Royal Society of Chemistry, 2020, 7 (3), pp.678-688. ⟨10.1039/C9QI01148J⟩
Inorganic Chemistry Frontiers, Royal Society of Chemistry, 2020, 7 (3), pp.678-688. ⟨10.1039/c9qi01148j⟩
Ruthenium and osmium complexes have been shown to bypass several resistance mechanisms of platinum anticancer drugs, suggesting that they might represent therapeutic alternatives. However, the resistance mechanisms that may alter the cytotoxicity of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3821807e383b9c46a4c3ce35ca4296b2
https://hal.archives-ouvertes.fr/hal-03013615
https://hal.archives-ouvertes.fr/hal-03013615
Autor:
Jessica J. Miller, Tim Storr, Christophe Orvain, Anais Blanchet, Diego Martelino, Derek J. Wilson, Lucienne Nouchikian, Ryan M. Clarke, Yasmin Reviriot, Christian Gaiddon
Publikováno v:
Chemical Science
Chemical Science, The Royal Society of Chemistry, 2019, Epub ahead of print. ⟨10.1039/c9sc04151f⟩
Chemical Science, 2019, Epub ahead of print. ⟨10.1039/c9sc04151f⟩
Chemical Science, The Royal Society of Chemistry, 2019, Epub ahead of print. ⟨10.1039/c9sc04151f⟩
Chemical Science, 2019, Epub ahead of print. ⟨10.1039/c9sc04151f⟩
International audience; Protein misfolding and aggregation contributes to the development of a wide range of diseases. In cancer, over 50% of diagnoses are attributed to p53 malfunction due to missense mutations, many of which result in protein misfo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7363bcdec92671d3aa0d33e9ebbe371c
https://www.hal.inserm.fr/inserm-02364138
https://www.hal.inserm.fr/inserm-02364138
Autor:
Isabelle Gross, Georg Mellitzer, Benoit Romain, Marjorie Sidhoum, Michel Pfeffer, Xiangjun Meng, Christian Gaiddon, Alain C. Jung, Jean-Batiste Delhorme, Aina Venkatasamy
Publikováno v:
Molecules
Molecules, 2021, 26 (17), pp.5386. ⟨10.3390/molecules26175386⟩
Molecules, Vol 26, Iss 5386, p 5386 (2021)
Molecules, MDPI, 2021, 26 (17), pp.5386. ⟨10.3390/molecules26175386⟩
Molecules, 2021, 26 (17), pp.5386. ⟨10.3390/molecules26175386⟩
Molecules, Vol 26, Iss 5386, p 5386 (2021)
Molecules, MDPI, 2021, 26 (17), pp.5386. ⟨10.3390/molecules26175386⟩
International audience; Metal complexes have been used to treat cancer since the discovery of cisplatin and its interaction with DNA in the 1960’s. Facing the resistance mechanisms against platinum salts and their side effects, safer therapeutic ap
Autor:
Benoit Romain, Jean-Baptiste Delhorme, Cécile Brigand, Simone Manfredelli, Aina Venkatasamy, Christian Gaiddon, Serge Rohr
Publikováno v:
Annals of Surgical Oncology
Annals of Surgical Oncology, Springer Verlag, 2017, 24 (11), pp.3324-3330. ⟨10.1245/s10434-017-5945-9⟩
Annals of Surgical Oncology, 2017, 24 (11), pp.3324-3330. ⟨10.1245/s10434-017-5945-9⟩
Annals of Surgical Oncology, Springer Verlag, 2017, 24 (11), pp.3324-3330. ⟨10.1245/s10434-017-5945-9⟩
Annals of Surgical Oncology, 2017, 24 (11), pp.3324-3330. ⟨10.1245/s10434-017-5945-9⟩
International audience; PURPOSE:To evaluate the impact of a feeding jejunostomy (FJ) on the preoperative management of patients with an oesogastric adenocarcinoma (OGA).METHODS:From January 2007 to December 2014, patients with potentially resectable
Autor:
Alain C. Jung, Sylvie Job, Laurent Brino, Eric Guérin, Aurélien de Reyniès, Nelly Etienne-Selloum, Bohdan Wasylyk, Cyril Bour, Betty Heller, Christian Gaiddon, Christine Macabre, Christine Wasylyk, Amélie Weiss, Sonia Ledrappier
Publikováno v:
Cancers, Vol 11, Iss 6, p 795 (2019)
Cancers
Cancers, 2019, 11 (6), pp.795. ⟨10.3390/cancers11060795⟩
Cancers, MDPI, 2019, 11 (6), pp.795. ⟨10.3390/cancers11060795⟩
Volume 11
Issue 6
Cancers
Cancers, 2019, 11 (6), pp.795. ⟨10.3390/cancers11060795⟩
Cancers, MDPI, 2019, 11 (6), pp.795. ⟨10.3390/cancers11060795⟩
Volume 11
Issue 6
The management of locally advanced head and neck squamous cell carcinoma (HNSCC) with Cetuximab, a monoclonal antibody targeting the epidermal growth factor receptor (EGFR), achieves only moderate response rates, and clinical trials that evaluated EG
Autor:
Alice Santoro, Peter Faller, Manuel David Peris-Díaz, Christian Gaiddon, Òscar Palacios, Bertrand Vileno, Gilles Riegel, Artur Krężel
Publikováno v:
Metallomics
Metallomics, Royal Society of Chemistry, 2019, 11 (5), pp.994-1004. ⟨10.1039/C9MT00061E⟩
Metallomics, Royal Society of Chemistry, 2019, 11 (5), pp.994-1004. ⟨10.1039/C9MT00061E⟩
Thiosemicarbazones (TSCs) are a class of strong metal ion ligands, which are currently being investigated for several applications, such as anticancer treatment. In addition to these ligands only, which exert their activity upon interaction with meta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::458ffbfdf03cd202b7b1be2708ead066
http://xlink.rsc.org/?DOI=C9MT00061E
http://xlink.rsc.org/?DOI=C9MT00061E