Zobrazeno 101 - 107
of 107
pro vyhledávání: '"Christian Gaiddon"'
Autor:
Riegel, Gilles
Publikováno v:
Cancer. Université de Strasbourg, 2019. English. ⟨NNT : 2019STRAJ071⟩
Cancer treatment is still based on surgery associated with platinum-based chemotherapy. These drugs induce side effects and are sensitive to resistance mechanisms. This shows the need to develop new anticancer therapies among which ruthenium compound
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1398::db35e40400d63bb19f9de77e23abfc15
https://theses.hal.science/tel-03510319/document
https://theses.hal.science/tel-03510319/document
Autor:
Spaety, Marie-Élodie
Publikováno v:
Cancer. Université de Strasbourg, 2016. English. ⟨NNT : 2016STRAJ043⟩
Gastric cancer (GC) is treated by surgical resection combined with chemotherapy based on platinum compounds. The increase in chemotherapy resistance reinforces the need to identify robust molecular markers to tailor treatment and develop targeted the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::1a4a9e226f527d3c86d827b127e6ebe6
https://tel.archives-ouvertes.fr/tel-01561028/document
https://tel.archives-ouvertes.fr/tel-01561028/document
Autor:
Araujo de Abreu, Paula
Publikováno v:
Rhumatology and musculoskeletal system. Université de Strasbourg, 2016. English. ⟨NNT : 2016STRAJ065⟩
Muscle atrophy in cachexia results from the imbalance between protein synthesis and degradation due to activation of the ubiquitin-proteasome pathway. Literature suggests that p53 family members play a role in controlling proliferation, differentiati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1398::801cd096ccf13da84689bb5c09abee6a
https://theses.hal.science/tel-01565199
https://theses.hal.science/tel-01565199
Autor:
Licona, Cynthia
Publikováno v:
Pharmacology. Université de Strasbourg, 2015. English. ⟨NNT : 2015STRAJ017⟩
Cancer is one of the leading causes of death in the world. To treat cancer, several therapeutic approaches exist. Chemotherapy in combination with surgery is one of the most used. Organometallic compounds such as platinum salts represent a reference
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1398::d5e77604ef034d6b2e38fd2f9202e97e
https://theses.hal.science/tel-01357138
https://theses.hal.science/tel-01357138
Autor:
Blanchard, Orphée
Publikováno v:
Neurobiologie. Université de Strasbourg, 2014. Français. ⟨NNT : 2014STRAJ032⟩
The transcription factor p73 is implicated in neurodegenerativ diseases (Alzheimer disease, neuroblastoma…) by regulating cell cycle, neuronal apoptosis and differenciation.Identifying the post-translationnal modifications on p73 would allow to bet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::982946f4a23fdfdd4ade9fc0868fe2d3
https://tel.archives-ouvertes.fr/tel-01647211/file/BLANCHARD_Orphee_2014_ED414.pdf
https://tel.archives-ouvertes.fr/tel-01647211/file/BLANCHARD_Orphee_2014_ED414.pdf
Autor:
von Grabowiecki, Yannick
Publikováno v:
Genomics [q-bio.GN]. Université de Strasbourg, 2013. English. ⟨NNT : 2013STRAJ126⟩
The p53 family of transcription factors in muscular atrophy - Involvements in Amyotrophic Lateral Sclerosis and cachexia Muscular atrophy is a dangerous condition found in several diseases. In amyotrophic lateral sclerosis (ALS), a rare neuromuscular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1398::a8bd836c29d76e48aa282b65261626e7
https://theses.hal.science/tel-01151413
https://theses.hal.science/tel-01151413