Zobrazeno 11 - 20
of 115
pro vyhledávání: '"Chihiro Morishima"'
Autor:
Marc S. Ernstoff, Hing C. Wong, Martin A. Cheever, Amy D. Rock, Peter R. Rhode, Monica Jones, Jack O. Egan, Judith C. Kaiser, Steven P. Fling, Andreanne M. Lacroix, Shernan G. Holtan, Ann W. Silk, Sylvia M. Lee, Jeffrey S. Miller, Vamsidhar Velcheti, Chihiro Morishima, Kim Margolin
Supplementary Figure 1-3 Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5afa04c5632d390b11e61ebbd0008456
https://doi.org/10.1158/1078-0432.22469901
https://doi.org/10.1158/1078-0432.22469901
Autor:
Marc S. Ernstoff, Hing C. Wong, Martin A. Cheever, Amy D. Rock, Peter R. Rhode, Monica Jones, Jack O. Egan, Judith C. Kaiser, Steven P. Fling, Andreanne M. Lacroix, Shernan G. Holtan, Ann W. Silk, Sylvia M. Lee, Jeffrey S. Miller, Vamsidhar Velcheti, Chihiro Morishima, Kim Margolin
Purpose: IL15 induces the activation and proliferation of natural killer (NK) and memory CD8+ T cells and has preclinical antitumor activity. Given the superior activity and favorable kinetics of ALT-803 (IL15N72D:IL15RαSu/IgG1 Fc complex) over reco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::386676f2f3598b4c8df5385ba0517278
https://doi.org/10.1158/1078-0432.c.6527382.v1
https://doi.org/10.1158/1078-0432.c.6527382.v1
Autor:
Marc S. Ernstoff, Hing C. Wong, Martin A. Cheever, Amy D. Rock, Peter R. Rhode, Monica Jones, Jack O. Egan, Judith C. Kaiser, Steven P. Fling, Andreanne M. Lacroix, Shernan G. Holtan, Ann W. Silk, Sylvia M. Lee, Jeffrey S. Miller, Vamsidhar Velcheti, Chihiro Morishima, Kim Margolin
Supplemental Figure 1. Effect of ALT-803 treatment on white blood cell and lymphocyte counts in i.v. dose cohorts Supplemental Figure 2. Circulating NK cell expansion during ALT-803 treatment Supplemental Figure 3. Effect of subcutaneous ALT-803 on c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aeb7495845ae7a2a25b3ea58d3810e26
https://doi.org/10.1158/1078-0432.22469895.v1
https://doi.org/10.1158/1078-0432.22469895.v1
Publikováno v:
The Journal of Applied Laboratory Medicine. 7:46-56
Background The 2019 classification criteria for systemic lupus erythematosus (SLE) includes an initial criterion requiring the presence of an antinuclear antibody (ANA), positive at a titer of at least 1:80 on HEp-2 cells, or equivalent. However, res
Autor:
Rebecca Treger, Patrick Mathias, Kathleen Hutchinson, Andrew Bryan, Anu Chaudhary, Susan Fink, Mark Wener, Chihiro Morishima
Publikováno v:
American Journal of Clinical Pathology. 158:S2-S3
Serum protein electrophoresis and immunofixation are used to detect the presence of monoclonal heavy and light immunoglobulin chains for the diagnosis of plasma cell neoplasms (PCN). In conjunction, the Freelite® assay has been used to detect excess
Autor:
Kunle Odunsi, Feng Qian, Amit A. Lugade, Han Yu, Melissa A. Geller, Steven P. Fling, Judith C. Kaiser, Andreanne M. Lacroix, Leonard D’Amico, Nirasha Ramchurren, Chihiro Morishima, Mary L. Disis, Lucas Dennis, Patrick Danaher, Sarah Warren, Van Anh Nguyen, Sudharshan Ravi, Takemasa Tsuji, Spencer Rosario, Wenjuan Zha, Alan Hutson, Song Liu, Shashikant Lele, Emese Zsiros, A. J. Robert McGray, Jessie Chiello, Richard Koya, Thinle Chodon, Carl D. Morrison, Vasanta Putluri, Nagireddy Putluri, Donald E. Mager, Rudiyanto Gunawan, Martin A. Cheever, Sebastiano Battaglia, Junko Matsuzaki
Publikováno v:
Sci Transl Med
To uncover underlying mechanisms associated with failure of indoleamine 2,3-dioxygenase 1 (IDO1) blockade in clinical trials, we conducted a pilot, window-of-opportunity clinical study in 17 patients with newly diagnosed advanced high-grade serous ov
Autor:
Davide Bedognetti, Patrick Danaher, Mary L. Disis, Brent A. Hanks, Chihiro Morishima, Nina Bhardwaj, Anna C. Pavlick, Andres M. Salazar, Jason J. Luke, Ena Wang, Sarah Warren, Philip Friedlander, Lisa Lundgren, Steven P. Fling, Marc S. Ernstoff, Ana Belen Blazquez, Tibor Keler, Brendan D. Curti, Martin A. Cheever, Sreekumar Balan, Leonard A D'Amico, Michael J. Yellin, Thomas A. Davis, Bruce W. Hess, Bob Salim, Laura Vitale, Joseph M. Beechem, Elad Sharon, Darawan Rinchai, Nirasha Ramchurren, Brian R. Gastman, Andrea Crocker, Thomas Hawthorne, Mark R. Albertini
Publikováno v:
Nature Cancer. 1:1204-1217
Generating responses to tumor antigens poses a challenge for immunotherapy. This phase II trial (NCT02129075) tested fms-like tyrosine kinase 3 (Flt3) ligand pre-treatment enhancement of responses to dendritic cell (DC)-targeting vaccines. We evaluat
Autor:
Paul Nghiem, Chihiro Morishima, Janis M. Taube, Evan Greene, Greg Finak, Raphael Gottardo, Steven P. Fling, Candice D. Church, Leonard A D'Amico, Nina Bhardwaj, Nirasha Ramchurren, Martin A. Cheever
Publikováno v:
Patterns, vol. 2, no. 12, pp. 100372
Patterns
Patterns
Summary We introduce a new method for single-cell cytometry studies, FAUST, which performs unbiased cell population discovery and annotation. FAUST processes experimental data on a per-sample basis and returns biologically interpretable cell phenotyp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92dc0b6873819de8f66c57374d3c3ef8
https://serval.unil.ch/resource/serval:BIB_4AF9E6EB0D95.P001/REF.pdf
https://serval.unil.ch/resource/serval:BIB_4AF9E6EB0D95.P001/REF.pdf
Autor:
Yevgeniy Yuzefpolskiy, Peter Morawski, Mitch Fahning, Cate Speake, Sandra Lord, Anu Chaudhary, Chihiro Morishima, Mark H. Wener, Mariko Kita, Lucas McCarthy, Jane H. Buckner, Daniel J. Campbell, Estelle Bettelli
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 208(7)
Multiple sclerosis (MS) is a demyelinating inflammatory disease of the CNS treated by diverse disease-modifying therapies that suppress the immune system. Severe acute respiratory syndrome coronavirus 2 mRNA vaccines have been very effective in immun
Autor:
Andreanne M. Lacroix, Steven P. Fling, Lawrence Fong, Chihiro Morishima, Frederick Millard, Nirasha Ramchurren, Russell K. Pachynski, Martin A. Cheever, Anne Gregoire, Lauren C. Harshman, Paul Monk, Omer Kucuk, Leonard A D'Amico, Leonard Joseph Appleman, Michel Morre, John D. Seigne, Caroline Duault, Judith C Kaiser, Russell Z. Szmulewitz, Evan Y. Yu, Bruce W. Hess, Rhonda L. Bitting, Holden T. Maecker
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 8 (2021)
Journal for immunotherapy of cancer, vol 9, iss 8
Journal for Immunotherapy of Cancer
Journal for immunotherapy of cancer, vol 9, iss 8
Journal for Immunotherapy of Cancer
BackgroundSipuleucel-T (sip-T) is a Food and Drug Administration (FDA)-approved autologous cellular immunotherapy for metastatic castration-resistant prostate cancer (mCRPC). We hypothesized that combining sip-T with interleukin (IL)-7, a homeostatic