Zobrazeno 91 - 100
of 439
pro vyhledávání: '"Carol A. Pollock"'
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Receptor-interacting protein kinase-3 (RIPK3) is a multifunctional regulator of cell death and inflammation. RIPK3 controls cellular signalling through the formation of the domain-like receptor family pyrin domain-containing 3 (NLRP3) inflammasome, w
Autor:
JINGWEI LI, MEG J. JARDINE, BRUCE NEAL, HIDDO L. HEERSPINK, CHRISTOPHER CANNON, RAJIV AGARWAL, GEORGE BAKRIS, DAVID M. CHARYTAN, DICK DE ZEEUW, ROBERT EDWARDS, TOM GREENE, ADEERA LEVIN, CAROL A. POLLOCK, NORM ROSENTHAL, DAVID C. WHEELER, HONG ZHANG, BERNARD ZINMAN, VLADO PERKOVIC, KENNETH W. MAHAFFEY, CLARE ARNOTT
Publikováno v:
Diabetes. 69
Background: The sodium glucose co-transporter 2 inhibitor canagliflozin reduced the risk of first hospitalization for heart failure (HHF) in the CREDENCE trial. The prevention of recurrent events is important to patients, clinicians and payers. In th
Autor:
David M. Charytan, Kenneth W. Mahaffey, Dick de Zeeuw, David C. Wheeler, Brendon L. Neuen, Carinna Hockham, Carol A. Pollock, Meg Jardine, Hiddo J.L. Heerspink, Rajiv Agarwal, Bruce Neal, Vlado Perkovic, Hong Zhang, Amy Kang, Tom Greene, Gian Luca Di Tanna, George L. Bakris, Bernard Zinman, Adeera Levin
Publikováno v:
Nephrology Dialysis Transplantation. 35
Background and Aims To describe genital mycotic infections (GMI) and urinary tract infections (UTI) in the CREDENCE trial, determine whether canagliflozin increased the risk of these infections overall and in subgroups, and describe predictors of ris
Autor:
JINGWEI LI, BRUCE NEAL, HIDDO L. HEERSPINK, CLARE ARNOTT, CHRISTOPHER CANNON, RAJIV AGARWAL, GEORGE BAKRIS, DAVID M. CHARYTAN, DICK DE ZEEUW, TOM GREENE, ADEERA LEVIN, RICHARD OH, CAROL A. POLLOCK, DAVID C. WHEELER, YSHAI YAVIN, HONG ZHANG, BERNARD ZINMAN, GIAN LUCA DI TANNA, VLADO PERKOVIC, KENNETH W. MAHAFFEY, MEG JARDINE
Publikováno v:
Diabetes. 69
The benefits of CANA for HF in people with T2D at CV risk appeared to be statistically mediated by erythrocyte concentration, serum urate, and urinary albumin:creatinine ratio (UACR) in the CANVAS Program. CANA reduced the risk of HF in patients with
Autor:
Naoki Kashihara, Juan Jesus Carrero, Carol A. Pollock, David C. Wheeler, Mitja Lainscak, Hiddo J.L. Heerspink, Carolyn S.P. Lam, Glen James, Stephen Nolan, Eiichiro Kanda, Mikhail Kosiborod, Juan Jose Garcia Sanchez, Tony Chen, Roberto Pecoits-Filho, Supriya Kumar
Publikováno v:
Nephrology Dialysis Transplantation. 35
Background and Aims In 2012, the Kidney Disease Improving Global Outcomes (KDIGO) guidelines recommended categorising and prognosticating chronic kidney disease (CKD) based on estimated glomerular filtration rate (eGFR) and urine albumin to creatinin
Autor:
Rajiv Agarwal, Brendon L. Neuen, Carol A. Pollock, Amy Kang, Gian Luca Di Tanna, Brendan Smyth, Hong Zhang, David M. Charytan, David C. Wheeler, Tom Greene, Bernard Zinman, Hiddo J.L. Heerspink, Kenneth W. Mahaffey, Bruce Neal, Dick de Zeeuw, Carinna Hockham, Meg Jardine, George L. Bakris, Adeera Levin, Vlado Perkovic
Publikováno v:
Nephrology Dialysis Transplantation. 35
Background and Aims The skin’s hypertonic microenvironment has a hypothesized protective antimicrobial function that may be disrupted by SGLT2i. The association between sodium glucose cotransporter inhibitors (SGLT2i) and genital mycotic infections
Publikováno v:
Frontiers in Cell and Developmental Biology
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Chronic kidney disease (CKD) is the end result of a plethora of renal insults, including repeated episodes of acute or toxic kidney injury, glomerular, or diabetic kidney disease. It affects a large number of the population worldwide, resulting in si
Autor:
Adeera Levin, Rose Qiu, Dick de Zeeuw, David M. Charytan, David C. Wheeler, Christopher P. Cannon, Bernard Zinman, Meg Jardine, Harpreet S. Bajaj, Gian Luca Di Tanna, Rajiv Agarwal, Kenneth W. Mahaffey, Megumi Oshima, Vlado Perkovic, Hiddo J.L. Heerspink, Carol A. Pollock, Bruce Neal, Hong Zhang, Norman Rosenthal, George L. Bakris, Zien Zhou, Scott Bull, Tao Sun, Tom Greene
Publikováno v:
Journal of the American Society of Nephrology, 31(5), 1128-1139. AMER SOC NEPHROLOGY
J Am Soc Nephrol
J Am Soc Nephrol
BACKGROUND: Canagliflozin reduced renal and cardiovascular events in people with type 2 diabetes in the CREDENCE trial. We assessed efficacy and safety of canagliflozin by initial estimated glomerular filtration rate (eGFR). METHODS: CREDENCE randoml
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75cc49e0de93f3c4191f2b4825756550
https://research.rug.nl/en/publications/05e58d3f-d008-43f7-9d77-9bc4dfb474fe
https://research.rug.nl/en/publications/05e58d3f-d008-43f7-9d77-9bc4dfb474fe
Autor:
Min Jun, Alan Cass, Germaine Wong, Louisa Sukkar, David Peiris, Roberto Pecoits-Filho, Celine Foote, John Knight, Martin Gallagher, Brendon L. Neuen, Carol A. Pollock, Kris Rogers, Tamara Young, David R. Sullivan, Amy Kang, Carinna Hockham, Meg Jardine
Publikováno v:
Diabetes Care
OBJECTIVE To determine the incidence of and factors associated with an estimated glomerular filtration rate (eGFR) RESEARCH DESIGN AND METHODS We identified people with diabetes in the EXamining ouTcomEs in chroNic Disease in the 45 and Up Study (EXT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61889df3f9055a480cde587563f48081
https://europepmc.org/articles/PMC7809711/
https://europepmc.org/articles/PMC7809711/
Autor:
Saabah B. Mahbub, Sonia Saad, Mahdieh Dashtbani Moghari, Ewa M. Goldys, Jared M. Campbell, Martin E. Gosnell, Ayad G. Anwer, Abbas Habibalahi, Carol A. Pollock
Detecting reactive oxygen species (ROS) that play a critical role as redox modulators and signalling molecules in biological systems currently requires invasive methods such as ROS - specific indicators for imaging and quantification. We developed a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53eb385c55a72b37119fbf329e901f18