Zobrazeno 11 - 20
of 263
pro vyhledávání: '"Carien L. Creutzberg"'
Autor:
Florine A. Eggink, Inge C. Van Gool, Alexandra Leary, Pamela M. Pollock, Emma J. Crosbie, Linda Mileshkin, Ekaterina S. Jordanova, Julien Adam, Luke Freeman-Mills, David N. Church, Carien L. Creutzberg, Marco De Bruyn, Hans W. Nijman, Tjalling Bosse
Publikováno v:
OncoImmunology, Vol 6, Iss 2 (2017)
High-risk endometrial cancer (EC) is an aggressive disease for which new therapeutic options are needed. Aims of this study were to validate the enhanced immune response in highly mutated ECs and to explore immune profiles in other EC subgroups. We e
Externí odkaz:
https://doaj.org/article/475adc4ab5f34a48a77118f7a1e7e850
Autor:
Marina Bagnoli, Ting Yan Shi, Charlie Gourley, Paul Speiser, Alexander Reuss, Hans W. Nijman, Carien L. Creutzberg, Suzy Scholl, Anastassia Negrouk, Mark F. Brady, Kosei Hasegawa, Katsutoshi Oda, Iain A. McNeish, Elise C. Kohn, Amit M. Oza, Helen MacKay, David Millan, Katherine Bennett, Clare Scott, Delia Mezzanzanica
Publikováno v:
Cells, Vol 8, Iss 3, p 200 (2019)
In the era of personalized medicine, the introduction of translational studies in clinical trials has substantially increased their costs, but provides the possibility of improving the productivity of trials with a better selection of recruited patie
Externí odkaz:
https://doaj.org/article/b32813236958434aaee4624554f30e0f
Autor:
Sarah Fremond, Sonali Andani, Jurriaan Barkey Wolf, Jouke Dijkstra, Sinéad Melsbach, Jan J Jobsen, Mariel Brinkhuis, Suzan Roothaan, Ina Jurgenliemk-Schulz, Ludy C H W Lutgens, Remi A Nout, Elzbieta M van der Steen-Banasik, Stephanie M de Boer, Melanie E Powell, Naveena Singh, Linda R Mileshkin, Helen J Mackay, Alexandra Leary, Hans W Nijman, Vincent T H B M Smit, Carien L Creutzberg, Nanda Horeweg, Viktor H Koelzer, Tjalling Bosse
Publikováno v:
The Lancet Digital Health, 5(2), e71-e82. Lancet Publishing Group
The Lancet Digital Health, 5(2), e71-e82. Elsevier
The Lancet Digital Health, 5(2), e71-e82. Elsevier Ltd.
The Lancet Digital Health, 5(2), e71-e82. Elsevier
The Lancet Digital Health, 5(2), e71-e82. Elsevier Ltd.
Background: Endometrial cancer can be molecularly classified into POLEmut, mismatch repair deficient (MMRd), p53 abnormal (p53abn), and no specific molecular profile (NSMP) subgroups. We aimed to develop an interpretable deep learning pipeline for wh
Autor:
David N. Church, Viktor H. Koelzer, Hans W. Nijman, Tjalling Bosse, Carien L. Creutzberg, Vincent T. Smit, Elzbieta M. van der Steen-Banasik, Jan J. Jobsen, Ludy C.H.W. Lutgens, Ina M. Jürgenliemk-Schulz, Michelle Osse, Kirsten D. Mertz, Annechien Plat, Alicia León-Castillo, Katarzyna Kedzierska, Ellen Stelloo, Remi A. Nout, Marco de Bruyn, Nanda Horeweg
Supplementary Tables 1-14 and Supplementary Figures 1-4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::053d0ebe34ebd8afd1aefeb61f40f9a1
https://doi.org/10.1158/2326-6066.22543677.v1
https://doi.org/10.1158/2326-6066.22543677.v1
Autor:
David N. Church, Viktor H. Koelzer, Hans W. Nijman, Tjalling Bosse, Carien L. Creutzberg, Vincent T. Smit, Elzbieta M. van der Steen-Banasik, Jan J. Jobsen, Ludy C.H.W. Lutgens, Ina M. Jürgenliemk-Schulz, Michelle Osse, Kirsten D. Mertz, Annechien Plat, Alicia León-Castillo, Katarzyna Kedzierska, Ellen Stelloo, Remi A. Nout, Marco de Bruyn, Nanda Horeweg
Optimum risk stratification in early-stage endometrial cancer combines clinicopathologic factors and the molecular endometrial cancer classification defined by The Cancer Genome Atlas (TCGA). It is unclear whether analysis of intratumoral immune infi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::598b00a1fe1b6386eaf503615b4db1bd
https://doi.org/10.1158/2326-6066.c.6550359
https://doi.org/10.1158/2326-6066.c.6550359
Autor:
Marco de Bruyn, Hans W. Nijman, David N. Church, Mark Glaire, Annechien Plat, Arjan Kol, Carien L. Creutzberg, Elisabeth C. van der Slikke, Fenne L. Komdeur, Maartje C.A. Wouters, Florine A. Eggink, Inge C. van Gool, Tjalling Bosse, Kim de Lange, Pieter van der Vlies, Thalina M. Prins, Roland Arnold, Joyce M. Lubbers, Hagma H. Workel
Supplementary Tables 1-6, 8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4be165541ea1a0633812bc569b5ce1b5
https://doi.org/10.1158/2326-6066.22542721
https://doi.org/10.1158/2326-6066.22542721
Autor:
Marco de Bruyn, Hans W. Nijman, David N. Church, Mark Glaire, Annechien Plat, Arjan Kol, Carien L. Creutzberg, Elisabeth C. van der Slikke, Fenne L. Komdeur, Maartje C.A. Wouters, Florine A. Eggink, Inge C. van Gool, Tjalling Bosse, Kim de Lange, Pieter van der Vlies, Thalina M. Prins, Roland Arnold, Joyce M. Lubbers, Hagma H. Workel
The chemokine CXCL13 mediates recruitment of B cells to tumors and is essential for the formation of tertiary lymphoid structures (TLSs). TLSs are thought to support antitumor immunity and are associated with improved prognosis. However, it remains u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::297002341a808ca5c7079200d97c33da
https://doi.org/10.1158/2326-6066.c.6550027.v1
https://doi.org/10.1158/2326-6066.c.6550027.v1
Autor:
Marco de Bruyn, Hans W. Nijman, David N. Church, Mark Glaire, Annechien Plat, Arjan Kol, Carien L. Creutzberg, Elisabeth C. van der Slikke, Fenne L. Komdeur, Maartje C.A. Wouters, Florine A. Eggink, Inge C. van Gool, Tjalling Bosse, Kim de Lange, Pieter van der Vlies, Thalina M. Prins, Roland Arnold, Joyce M. Lubbers, Hagma H. Workel
Supplementary Table 7. Differential expression analysis of CD103+ vs CD103- CD8+ cytotoxic T cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46eff6dced9b21bb12bb6428abffaeff
https://doi.org/10.1158/2326-6066.22542724.v1
https://doi.org/10.1158/2326-6066.22542724.v1
Figure S3 from Amplification of 1q32.1 Refines the Molecular Classification of Endometrial Carcinoma
Autor:
Tjalling Bosse, Diether Lambrechts, Frédéric Amant, Xavier Matias-Guiu, Jean-Christophe Marine, Karen Willekens, Michael Dewaele, Diego A. Garcia-Dios, Matthieu Moisse, Remi A. Nout, Carien L. Creutzberg, Elisabeth M. Osse, Ellen Stelloo, Jeroen Depreeuw
Frequency of amplifications, GISTIC q-value and Cox regression P value for all regions in 1q locus for cluster 2, 3 and 4 ECs (n= 268).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10dcbab3ff6180823aff5260b222d5ab
https://doi.org/10.1158/1078-0432.22466567
https://doi.org/10.1158/1078-0432.22466567
Autor:
Tjalling Bosse, Diether Lambrechts, Frédéric Amant, Xavier Matias-Guiu, Jean-Christophe Marine, Karen Willekens, Michael Dewaele, Diego A. Garcia-Dios, Matthieu Moisse, Remi A. Nout, Carien L. Creutzberg, Elisabeth M. Osse, Ellen Stelloo, Jeroen Depreeuw
Purpose: Molecular classification of endometrial cancer identified distinct molecular subgroups. However, the largest subset of endometrial cancers remains poorly characterized and is referred to as the “nonspecific molecular profile” (NSMP) subg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10797c55e9a57869e64eed7d145e3445
https://doi.org/10.1158/1078-0432.c.6526352
https://doi.org/10.1158/1078-0432.c.6526352