Zobrazeno 41 - 50
of 72
pro vyhledávání: '"Cagla Eroglu"'
Autor:
Nicola J. Allen, Cagla Eroglu
Publikováno v:
Neuron. 96(3)
Astrocytes, the most abundant glial cells in the mammalian brain, are critical regulators of brain development and physiology through dynamic and often bidirectional interactions with neuronal synapses. Despite the clear importance of astrocytes for
Autor:
Sehwon Koh, Bin Lu, Ian Ross Harris, William J. Chen, Joshua Saylor, Cagla Eroglu, Shaomei Wang, Nadine Sophia Dejneka, Sergey Girman
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 38(12)
Human umbilical tissue-derived cells (hUTC or palucorcel) are currently under clinical investigation for the treatment of geographic atrophy, a late stage of macular degeneration, but how hUTC transplantation mediates vision recovery is not fully elu
Autor:
Cagla Eroglu, Katherine T. Baldwin
Publikováno v:
Current opinion in neurobiology. 45
Astrocytes are morphologically complex cells that perform a wide variety of critical functions in the brain. As a structurally and functionally integrated component of the synapse, astrocytes secrete proteins, lipids, and small molecules that bind ne
Autor:
MI Ozlu, T Ustunkaya, Ioannis Dragatsis, Spencer U. McKinstry, WC Risher, YB Karadeniz, Henry H. Yin, Scott Zeitlin, K Serafin-Molina, Cagla Eroglu, Volodya Y. Hayrapetyan, AK Worthington
Publikováno v:
Journal of Neuroscience. 34:9455-9472
Huntington's disease (HD) is a neurodegenerative disease caused by the expansion of a poly-glutamine (poly-Q) stretch in the huntingtin (Htt) protein. Gain-of-function effects of mutant Htt have been extensively investigated as the major driver of ne
Autor:
Jeffrey A. Stogsdill, Cagla Eroglu
Publikováno v:
Current opinion in neurobiology. 42
In the brain, the formation of complex neuronal networks amenable to experience-dependent remodeling is complicated by the diversity of neurons and synapse types. The establishment of a functional brain depends not only on neurons, but also non-neuro
Autor:
Eray Enustun, Zeynep Ertuz, Wandilson dos Santos Rodrigues, Arin Pamukcu, Ru-Rong Ji, Il Hwan Kim, Nisha S. Pulimood, Scott H. Soderling, Alex C. Manhães, Louis-Jan Pilaz, Alexandre E. Medina, Yong Ho Kim, Sandeep Singh, Cagla Eroglu, Debra L. Silver, Peter Scheiffele, Hayley Dingsdale, Jeffrey A. Stogsdill
Proper establishment of synapses is critical for constructing functional circuits. Interactions between presynaptic neurexins and postsynaptic neuroligins coordinate the formation of synaptic adhesions. An isoform code determines the direct interacti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ebbb559ff8b9bdf4340adc2944af15b
https://europepmc.org/articles/PMC4715262/
https://europepmc.org/articles/PMC4715262/
Autor:
W. Christopher Risher, Cagla Eroglu
Publikováno v:
Matrix Biology. 31:170-177
Thrombospondins (TSPs) are a family of large, oligomeric multidomain glycoproteins that participate in a variety of biological functions as part of the extracellular matrix (ECM). Through their associations with a number of binding partners, TSPs med
Cell therapy demonstrates great potential for the treatment of neurological disorders. Human umbilical tissue-derived cells (hUTCs) were previously shown to have protective and regenerative effects in animal models of stroke and retinal degeneration,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30b9117d58a77fbe4189338f4e7dfbe4
https://europepmc.org/articles/PMC4659827/
https://europepmc.org/articles/PMC4659827/
Astrocytes, through their close associations with synapses, can monitor and alter synaptic function, thus actively controlling synaptic transmission in the adult brain. Besides their important role at adult synapses, in the last three decades a numbe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::629efe9a3694785227773193e01505b1
https://europepmc.org/articles/PMC4527946/
https://europepmc.org/articles/PMC4527946/
Autor:
Dong Yan, Andrew D. Chisholm, Lezi E, Sehwon Koh, Nathalie Pujol, Ting Zhou, Cagla Eroglu, Marian Chuang, Hiroaki Matsunami, Ruchira Sharma
Publikováno v:
Neuron
Neuron, Elsevier, 2018, 97 (1), pp.125-138.e5. ⟨10.1016/j.neuron.2017.12.001⟩
Neuron, 2018, 97 (1), pp.125-138.e5. ⟨10.1016/j.neuron.2017.12.001⟩
Neuron, vol 97, iss 1
Neuron, Elsevier, 2018, 97 (1), pp.125-138.e5. ⟨10.1016/j.neuron.2017.12.001⟩
Neuron, 2018, 97 (1), pp.125-138.e5. ⟨10.1016/j.neuron.2017.12.001⟩
Neuron, vol 97, iss 1
Summary Infections have been identified as possible risk factors for aging-related neurodegenerative diseases, but it remains unclear whether infection-related immune molecules have a causative role in neurodegeneration during aging. Here, we reveal