Zobrazeno 71 - 80
of 104
pro vyhledávání: '"Brenda Gerull"'
Publikováno v:
Circulation: Cardiovascular Genetics. 4:472-474
In this issue of Circulation: Cardiovascular Genetics , Barsheshet et al shed novel and unexpected light on the genetics of syncope, defined as a transient loss of consciousness caused by cerebral hypoperfusion with spontaneous recovery. Syncope is v
Publikováno v:
Canadian Journal of Cardiology. 32:1576.e15-1576.e18
Andersen-Tawil syndrome (ATS) is caused by mutations in KCNJ2 (Kir2.1). It remains unclear whether dilated cardiomyopathy (DCM) is a primary feature of ATS. We studied a proband with typical physical features of ATS plus DCM and moderate to severe le
Publikováno v:
Canadian Journal of Cardiology. 32:S213
Autor:
Steven C. Greenway, Stacey Hume, Brenda Gerull, Nanette Alvarez, Michael Giuffre, Christoph Preuss, Gregor Andelfinger, Steven J.M. Jones, Yaoqing Shen, Nicole M. Roslin, Ross McLeod, Shing Hei Zhan
Publikováno v:
The Canadian journal of cardiology. 30(2)
Background The genetics of congenital heart disease (CHD) remain incompletely understood. Exome sequencing has been successfully used to identify disease-causing mutations in familial disorders in which candidate gene analyses and linkage mapping hav
Autor:
Peter Leong-Sit, Jean Champagne, Brenda Gerull, Robert M. Gow, George J. Klein, Lorne J. Gula, Shubhayan Sanatani, Allan C. Skanes, Christopher S. Simpson, Santabhanu Chakrabarti, Michael H. Gollob, Martin J. Gardner, Paul Angaran, Mario Talajic, Andrew D. Krahn, Raymond Yee, Jeff S. Healey, Vijay S. Chauhan, David H. Birnie, Riyaz Somani
Publikováno v:
Heart rhythm. 11(6)
Background Provocative testing with sodium channel blockers is advocated for the evaluation of unexplained cardiac arrest (UCA) with the primary purpose of unmasking the typical ECG features of Brugada syndrome. The Cardiac Arrest Survivors with Pres
Publikováno v:
Human Mutation. 11:179-182
Mutations in the human cardiac troponin T gene (TNNT2) are associated with familial hypertrophic cardiomyopathy (FHC) linked to chromosome 1q3 (CMH2). Mutation analyses of TNNT2 have been restricted to RNA-based screening methods because only the TNN
Autor:
Carole Ober, Kumaran Chandrasekharan, Jessica X. Chong, Oliver Strohm, Florian Kirchner, Darrel Waggoner, Brenda Gerull, Henry J. Duff, Julia Tagoe
Publikováno v:
Circulation. Cardiovascular genetics. 6(4)
Background— Dominant mutations in cellular junction proteins are the major cause of arrhythmogenic cardiomyopathy, whereas recessive mutations in those proteins cause cardiocutaneous syndromes such as Naxos and Carvajal syndrome. The Hutterites are
Autor:
Peter Leong-Sit, Raymond Yee, Shubhayan Sanatani, Jean Champagne, Brenda Gerull, George J. Klein, Martin J. Gardner, Jeff S. Healey, Kamran Ahmad, Vijay S. Chauhan, Christopher S. Simpson, Lorne J. Gula, Allan C. Skanes, Mario Talajic, Michael H. Gollob, Andrew D. Krahn, Emily Ballantyne, David H. Birnie
Publikováno v:
Circulation. Arrhythmia and electrophysiology. 5(5)
Background— Epinephrine infusion may unmask latent genetic conditions associated with cardiac arrest, including long-QT syndrome and catecholaminergic polymorphic ventricular tachycardia (VT). Methods and Results— Patients with unexplained cardia
Autor:
W. Yu, Steven C. Greenway, Brenda Gerull, Nanette Alvarez, M. Brundler, Raechel A. Ferrier, Andreas Brodehl, Michael Giuffre
Publikováno v:
Canadian Journal of Cardiology. 31:S147
Autor:
K. Martens, Brenda Gerull, Yong-Xiang Chen, A. Nygren, Darrell D. Belke, Andreas Brodehl, C. Diao, L. Garnett
Publikováno v:
Canadian Journal of Cardiology. 31:S64
BACKGROUND: Arrhythmogenic cardiomyopathy (AC) is an inherited heart disease associated with arrhythmias and right or biventricular dilation often leading to sudden cardiac death or heart failure. AC is mainly caused by mutations in five genes encodi