Zobrazeno 41 - 50
of 65
pro vyhledávání: '"Betül Kaya Çavuşoğlu"'
Autor:
Yusuf Özkay, Derya Osmaniye, Zafer Asım Kaplancıklı, Betül Kaya Çavuşoğlu, Begüm Nurpelin Sağlık, Ulviye Acar Çevik, Serkan Levent
Publikováno v:
Molecules
Volume 24
Issue 5
Molecules, Vol 24, Iss 5, p 861 (2019)
Volume 24
Issue 5
Molecules, Vol 24, Iss 5, p 861 (2019)
Alzheimer&rsquo
s disease (AD), one of the main causes of aged dementia, is a progressive and degenerative neurological disorder characterized by loss of cognition and memory. Although the symptomatic treatment of AD, particularly acetylcholines
s disease (AD), one of the main causes of aged dementia, is a progressive and degenerative neurological disorder characterized by loss of cognition and memory. Although the symptomatic treatment of AD, particularly acetylcholines
Autor:
Serkan Levent, Begüm Nurpelin Sağlık, Derya Osmaniye, Yusuf Özkay, Zafer Asım Kaplancıklı, Betül Kaya Çavuşoğlu, Ulviye Acar Çevik
A novel series of 1,3,5-trisubstituted-2-pyrazoline derivatives (4a-4k) was synthesized and their chemical structures characterized by 1H NMR, 13C NMR, and mass spectroscopy. These compounds were evaluated as inhibitors for of type A and type B monoa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2b3a5b9668dc57b0a23fd36a7178497
https://hdl.handle.net/11421/13815
https://hdl.handle.net/11421/13815
Autor:
Begüm Nurpelin Sağlık, Derya Osmaniye, Ulviye Acar Çevik, Yusuf Öztürk, Zafer Asım Kaplancıklı, Serkan Levent, Yusuf Özkay, Betül Kaya Çavuşoğlu, Sinem Ilgın
WOS: 000462472500010
PubMed ID: 30605888
New twenty compounds bearing thiazole ring (3a-3t) were designed and synthesized as monoamine oxidase (MAO) inhibitors. The fluorometric enzyme inhibition assay was used to determine the biological e
PubMed ID: 30605888
New twenty compounds bearing thiazole ring (3a-3t) were designed and synthesized as monoamine oxidase (MAO) inhibitors. The fluorometric enzyme inhibition assay was used to determine the biological e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f4a3a0607e49e3910580e5db5002c9f
https://hdl.handle.net/11421/13601
https://hdl.handle.net/11421/13601
Autor:
Ulviye Acar Çevik, Derya Osmaniye, Şükrü Beydemir, Yusuf Özkay, Serkan Levent, Betül Kaya Çavuşoğlu, Zafer Asım Kaplancıklı, Begüm Nurpelin Sağlık, Yeliz Demir, Ali Savaş Koparal, Sinem Ilgın
Publikováno v:
Bioorganic chemistry. 91
PubMed: 31382057
New sulfonamide-hydrazone derivatives (3a-3n) were synthesized to evaluate their inhibitory effects on purified human carbonic anhydrase (hCA) I and II. The inhibition profiles of the synthesized compounds on hCA I-II isoenzyme
New sulfonamide-hydrazone derivatives (3a-3n) were synthesized to evaluate their inhibitory effects on purified human carbonic anhydrase (hCA) I and II. The inhibition profiles of the synthesized compounds on hCA I-II isoenzyme
Autor:
Busra Korkut Celikates, Serkan Levent, Ulviye Acar Çevik, Derya Osmaniye, Yusuf Özkay, Betül Kaya Çavuşoğlu, Begüm Nurpelin Sağlık, Zafer Asım Kaplancıklı, Sinem Ilgın
Publikováno v:
European Journal of Medicinal Chemistry. 210:112979
Phortress is an anticancer prodrug, which has active metabolite (5F-203) being potent agonist of the aryl hydrocarbon receptor (AhR). The 5F-203 switches on cytochrome P450 CYP1A1 gene expression and thus exhibits anticancer activity. In this study,
Autor:
Derya Osmaniye, Serkan Levent, Zafer Asım Kaplancıklı, Yusuf Özkay, Begüm Nurpelin Sağlık, Ulviye Acar Çevik, Betül Kaya Çavuşoğlu
Publikováno v:
Archiv der Pharmazie. 354:2000273
A new series of chalcones (1-9) possessing an SO2 CH3 COX-2 pharmacophore at the para position of the C-1 phenyl ring was synthesized via the Claisen-Schmidt condensation reaction and examined for their inhibition potential against cyclooxygenase (CO
WOS: 000435587600002
Objective: The advent of resistant pathogenic microorganisms against current antimicrobial drugs prompted scientists to investigate novel molecules with new mechanisms. In this paper, some new 2-[2-[4-(ethyl/phenyl)cyclohexy
Objective: The advent of resistant pathogenic microorganisms against current antimicrobial drugs prompted scientists to investigate novel molecules with new mechanisms. In this paper, some new 2-[2-[4-(ethyl/phenyl)cyclohexy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dffcc72ddcaa5cfe88de609e41981237
https://hdl.handle.net/11421/13621
https://hdl.handle.net/11421/13621
WOS: 000453472300015
PubMed ID: 29308744
Background: The lack of selectivity and development of drug-resistance encourage researchers to search for novel, more efficient and multi-targeted agents with less toxicity. Objective: In this paper
PubMed ID: 29308744
Background: The lack of selectivity and development of drug-resistance encourage researchers to search for novel, more efficient and multi-targeted agents with less toxicity. Objective: In this paper
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d448942ed18ea8d5dca256ccaea4b8f6
https://hdl.handle.net/11421/13500
https://hdl.handle.net/11421/13500
Autor:
Derya Osmaniye, Serkan Levent, Zafer Asım Kaplancıklı, Yusuf Özkay, Begüm Nurpelin Sağlık, Abdullah Burak Karaduman, Betül Kaya Çavuşoğlu, Ulviye Acar Çevik
Publikováno v:
Molecules, Vol 23, Iss 1, p 60 (2017)
Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry
Molecules; Volume 23; Issue 1; Pages: 60
Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry
Molecules; Volume 23; Issue 1; Pages: 60
WOS: 000425082500056
PubMed ID: 29283399
Twenty-six novel thiosemicarbazone derivative B1-B26 were synthesized via condensation reactions between the corresponding thiosemicarbazides and aldehydes. The chemical characterization of the compo
PubMed ID: 29283399
Twenty-six novel thiosemicarbazone derivative B1-B26 were synthesized via condensation reactions between the corresponding thiosemicarbazides and aldehydes. The chemical characterization of the compo
Publikováno v:
European journal of medicinal chemistry. 144
WOS: 000425198100020
PubMed ID: 29274492
In search of potent and safe antifungal agents, herein, we report the synthesis, characterization and biological activities of triazole-oxadiazole compounds. The structural verification of the molecu
PubMed ID: 29274492
In search of potent and safe antifungal agents, herein, we report the synthesis, characterization and biological activities of triazole-oxadiazole compounds. The structural verification of the molecu