Zobrazeno 61 - 70
of 309
pro vyhledávání: '"Barbara McKnight"'
Autor:
Lin Y. Chen, Barbara N. Harding, Barbara McKnight, Susan R. Heckbert, Bruce M. Psaty, James S. Floyd, Elsayed Z. Soliman, Faye L. Norby
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 11 (2021)
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 11 (2021)
Background High blood pressure (BP) is a well‐known risk factor for atrial fibrillation (AF), but a single BP measurement may provide limited information about AF risk in older adults. Methods and Results This study included 1256 MESA (Multi‐Ethn
Autor:
Joanne Michelle D. Gomez, Nona Sotoodehnia, Jainy J. Savla, Henry D. Huang, Barbara McKnight, Timothy R. Larsen, Richard Cheng, Sina A. Gharib, Rozenn N. Lemaitre, Neal A. Chatterjee, Paul N. Jensen, Andrew W. Harris, Jeanne M Du-Fay-de-Lavallaz, Daniel D Nguyen
Publikováno v:
Influenza and Other Respiratory Viruses
COVID‐19 has significant case fatality. Glucocorticoids are the only treatment shown to improve survival, but only among patients requiring supplemental oxygen. WHO advises patients to seek medical care for “trouble breathing,” but hypoxemic pa
Autor:
Ci Song, Christopher J. O'Donnell, Weihong Tang, Karl C. Desch, Xiuqing Guo, Aaron R. Folsom, Rasika A. Mathias, David-Alexandre Trégouët, Eleanor M. Simonsick, Jerome I. Rotter, Ming-Huei Chen, Germán D. Carrasquilla, Winfried März, Nicholas L. Smith, Pierre-Emmanuel Morange, Russel Tracy, Maria Sabater-Lleal, Diane M. Becker, Jie Yao, Lisa R. Yanek, Oluf Pedersen, Tuomas O. Kilpeläinen, Hampton L. Leonard, Jennifer A. Brody, Gerard Temprano-Sagrera, Allan Linneberg, Florian Thibord, Torben Hansen, Marcus E. Kleber, Mary Cushman, Jack Pattee, Lewis C. Becker, Hugh Watkins, Niels Grarup, Marta Guindo-Martínez, Nathan Pankratz, Anders Hamsten, Ayse Bilge Ozel, Angela Silveira, Mike A. Nalls, Benjamin Rodriguez, Kent D. Taylor, Laura M. Raffield, Andrew D. Johnson, Paul S. de Vries, Barbara McKnight, Graciela E. Delgado, Alanna C. Morrison, Beata Gyorgy, Bruce M. Psaty
Publikováno v:
Journal of Thrombosis and Haemostasis
Journal of Thrombosis and Haemostasis, Wiley, 2021, ⟨10.1111/jth.15345⟩
JOURNAL OF THROMBOSIS AND HAEMOSTASIS
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
J Thromb Haemost
Journal of Thrombosis and Haemostasis, 2021, ⟨10.1111/jth.15345⟩
Journal of thrombosis and haemostasis : JTH, vol 19, iss 8
Journal of Thrombosis and Haemostasis, Wiley, 2021, ⟨10.1111/jth.15345⟩
JOURNAL OF THROMBOSIS AND HAEMOSTASIS
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
J Thromb Haemost
Journal of Thrombosis and Haemostasis, 2021, ⟨10.1111/jth.15345⟩
Journal of thrombosis and haemostasis : JTH, vol 19, iss 8
BackgroundUse of targeted exome-arrays with common, rare variants and functionally enriched variation has led to discovery of new genes contributing to population variation in risk factors. Plasminogen activator-inhibitor 1 (PAI-1), tissue plasminoge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1922d03d8fbb3c0db519c3c36aad91f8
https://hal.archives-ouvertes.fr/hal-03274625
https://hal.archives-ouvertes.fr/hal-03274625
Autor:
Chani J. Hodonsky, Antoine R Baldassari, Colleen M. Sitlani, Christy L. Avery, Barbara McKnight, Heather M. Highland
Publikováno v:
Hum Mol Genet
Genome-wide association studies have been successful mapping loci for individual phenotypes, but few studies have comprehensively interrogated evidence of shared genetic effects across multiple phenotypes simultaneously. Statistical methods have been
Autor:
Andrew N. Hoofnagle, Paul N. Jensen, Barbara V. Howard, Nona Sotoodehnia, Colleen M. Sitlani, Jason G. Umans, Chaoyu Yu, Amanda M. Fretts, Rozenn N. Lemaitre, David S. Siscovick, Irena B. King, Barbara McKnight
Publikováno v:
EBioMedicine
Background Animal studies suggest sphingolipids as an early marker of impaired glucose metabolism; however, research in humans is limited. We evaluated whether individual sphingolipid species were associated with fasting plasma glucose and incident i
Autor:
Shirley A.A. Beresford, Corrine Huber, Caitlin Hawley, Amanda M. Fretts, Barbara V. Howard, Arlette Hager, Barbara McKnight, Marcia O'Leary, Anne N. Thorndike, Meagan C Brown, Jason G. Umans, India J Ornelas, Lyle G. Best
Publikováno v:
BMC Public Health
BMC Public Health, Vol 21, Iss 1, Pp 1-15 (2021)
BMC Public Health, Vol 21, Iss 1, Pp 1-15 (2021)
Background The prevalence of poor diet quality and type 2 diabetes are exceedingly high in many rural American Indian (AI) communities. Because of limited resources and infrastructure in some communities, implementation of interventions to promote a
Autor:
Unnur Styrkarsdottir, Daniel I. Chasman, Rehannah Borup, Anne B. Newman, Kristina W. Olsen, Lude Franke, Stefania Bandinelli, Nora Franceschini, Celine M. Vachon, Nicholas J. Timpson, James F. Wilson, Micaella Joaquim, Christa Meisinger, Felix R. Day, Charles Kooperberg, Qin Wang, Pascal Timshel, Dennis O. Mook-Kanamori, Luigi Ferrucci, Jennifer A. Smith, Miriam Dwek, Pascal Guénel, Claus Yding Andersen, Peter A. Fasching, Sven Bergmann, Thomas Meitinger, Nicholas Bowker, Jane L. Tarry-Adkins, Jeremy A. Daniel, Katharina E. Schraut, Mikael Eriksson, Amruta Shrikhande, Jacques E. Rossouw, Amber N. Wilcox, Simon S. Cross, Stasa Stankovic, Montserrat Garcia-Closas, Mohammad Arfan Ikram, Annette Peters, David Schlessinger, Sheila Ulivi, Mònica Ferrer-Roda, Immaculata De Vivo, Michela Traglia, Jessica Tyrrell, Paul R. H. J. Timmers, Rico Rueedi, Ko Willems van Dijk, N. Charlotte Onland-Moret, Doris Stöckl, Anthony J. Swerdlow, Paul M. Ridker, Zoltán Kutalik, Patrick Deelen, Gerardo Heiss, Marie Louise Grøndahl, Alison M. Dunning, Dale R. Nyholt, Nicholas J. Wareham, Reedik Mägi, Stephen J. Chanock, Martina La Bianca, Ozren Polasek, Daniel F. Gudbjartsson, Rebecca D. Jackson, Alison D. Murray, Lynda M. Rose, Hironori Abe, Joanne M. Murabito, Henry Völzke, Daniela Ruggiero, Dorret I. Boomsma, Harald Grallert, Stefania Benonisdottir, Javier Martin Gonzalez, Esther M. John, Natalia Perjakova, Georgia Chenevix-Trench, John R. B. Perry, Jenny Chang-Claude, Archie Campbell, Teresa Nutile, Ellen W. Demerath, Robin N Beaumont, Jouke J. Hottenga, Albert V. Smith, David Karasik, Linda Broer, Raymond Noordam, Wei He, Niclas Håkansson, Catherine E. Aiken, Robert Karlsson, Christopher A. Haiman, Massimo Mangino, Melissa C. Southey, Sharon L.R. Kardia, Nicholas G. Martin, Jodie N. Painter, Peter K. Joshi, Gonneke Willemsen, Lenore J. Launer, Alicja Wolk, Konstantin Strauch, Stig E. Bojesen, Manjeet K. Bolla, Allison W. Kurian, Renée de Mutsert, Joop S.E. Laven, Antonella Mulas, Igor Rudan, Vallari Shukla, Kathyrn L Lunetta, Susan E. Ozanne, Loic Le Marchand, Jenny A. Visser, Gad Rennert, Jennifer A. Brody, Paul D.P. Pharoah, Tune H. Pers, Sara Lindström, Ignasi Roig, Angela Cox, Unnur Þorsteinsdottir, Graham G. Giles, Toshiko Tanaka, Eva Hoffmann, Melissa A. Troester, Claudia Langenberg, Serena Sanna, Julie E. Buring, Anna Pujol, Mike A. Nalls, Kamila Czene, Tõnu Esko, Jian'an Luan, Lili Milani, Iffat Rahman, Sarah E. Medland, Caterina Barbieri, Emil Peter Trane Hertz, Behrooz Z. Alizadeh, David G. Hunter, Sandra Turon, Antonietta Robino, Marina Ciullo, Barbara McKnight, Chunyan He, Bruce H. R. Wolffenbuttel, David R. Weir, Daniela Toniolo, Ulrike Peters, George Davey-Smith, Saleh Shekari, Caroline Hayward, Elinor J. Sawyer, Patrick Sulem, Simin Liu, Tanguy Corre, Susan M. Ring, Peter Kraft, Alexander Teumer, Marjanka K. Schmidt, André G. Uitterlinden, Arto Mannermaa, Kristan J. Aronson, Heiko Becher, John L. Hopper, Alpa V. Patel, Joyce B. J. van Meurs, kConFab Investigators, Hamdi Mbarek, Frits R. Rosendaal, Minouk J. Schoemaker, Satoshi H. Namekawa, Miya Kudo Høffding, Fergus J. Couch, Nancy L. Pedersen, Jessica D. Faul, Patrik K. E. Magnusson, Jingmei Li, Christopher G. Scott, Joe Dennis, Genevieve Lachance, Ajuna Azad, Yongmei Liu, Elnaz Naderi, Andrew R. Wood, Yan Huang, Anna Murray, Annique Claringbould, Stephen Burgess, Jose E. Castelao, Brumat Marco, Eco J. C. de Geus, Veronique Vitart, Ken K. Ong, Kari Stefansson, Blair H. Smith, Francesco Cucca, Grant W. Montgomery, Emmanouil Saloustros, Andrés J. López-Contreras, Jonathan Marten, Håkan Olsson, Dale P. Sandler, Alice M. Arnold, Ana Martínez-Marchal, Tim D. Spector, Chloé Sarnowski, John J. Spinelli, Vilmundur Gudnason, Frank B. Hu, Thomas U. Ahearn, Hedy S. Rennert, Olivier B. Bakker, Eric Boerwinkle, Matthias W. Beckmann, Jazib Hussain, Uwe Völker, Peter Vollenweider, Douglas F. Easton, Irene L. Andrulis, Harry Campbell, Manuela Gago-Dominguez, Cari M. Kitahara, Yvonne T. van der Schouw, Eleonora Porcu, Annika Lindblom, Martha S. Linet, Meir J. Stampfer, Eulalia Catamo, Roger L. Milne, Ivana Kolcic, Annelie Augustinsson, Cinzia Sala, Debbie A Lawlor, Cristina Menni, Timothy M. Frayling, Lauren R. Teras, Marek Zygmunt, Tricia Lindstrom, Clarice R. Weinberg, Bruce M. Psaty, Thérèse Truong, Anna Marie Mulligan, Deborah J. Thompson, Per Hall, Rossella Sorice, Wei Zhao, Andres Metspalu, Katherine S. Ruth, Andrew F. Olshan, Massimo Mezzavilla, Murielle Bochud, Christian Gieger
Reproductive longevity is critical for fertility and impacts healthy ageing in women, yet insights into the underlying biological mechanisms and treatments to preserve it are limited. Here, we identify 290 genetic determinants of ovarian ageing, asse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b18fc43cd9f16417f22121a8650074ef
https://doi.org/10.1101/2021.01.11.20248322
https://doi.org/10.1101/2021.01.11.20248322
Autor:
Paul S. de Vries, Michael Laffan, Symen Ligthart, Weihong Tang, Myriam Fornage, Moniek P.M. de Maat, Barbara McKnight, Dipender Gill, Nathan Pankratz, Cavin K. Ward-Caviness, Eric Boerwinkle, Alisa S. Wolberg, Abbas Dehghan, Nicholas L. Smith, Jillian Maners, Stéphanie Debette, Alanna C. Morrison, Martin Dichgans
Publikováno v:
Blood
Blood, American Society of Hematology, 2020, 136 (26), pp.3062-3069. ⟨10.1182/blood.2019004781⟩
Blood, 136(26), 3062-3069. American Society of Hematology
Blood, American Society of Hematology, 2020, 136 (26), pp.3062-3069. ⟨10.1182/blood.2019004781⟩
Blood, 136(26), 3062-3069. American Society of Hematology
Fibrinogen is a key component of the coagulation cascade, and variation in its circulating levels may contribute to thrombotic diseases, such as venous thromboembolism (VTE) and ischemic stroke. Gamma prime (γ′) fibrinogen is an isoform of fibrino
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb7e77bb7c2fea0fc3aab46c442c555f
https://hal.archives-ouvertes.fr/hal-03177389
https://hal.archives-ouvertes.fr/hal-03177389
Autor:
Barbara McKnight, Nona Sotoodehnia, Barbara V. Howard, Irena B. King, Jason G. Umans, Maxwell Zeigler, Colleen M. Sitlani, Amanda M. Fretts, Julie Denham, Bruce M. Psaty, David S. Siscovick, Rheem A. Totah, Paul N. Jensen, Sina A. Gharib, Rozenn N. Lemaitre
Publikováno v:
EBioMedicine
EBioMedicine, Vol 66, Iss, Pp 103279-(2021)
EBioMedicine, Vol 66, Iss, Pp 103279-(2021)
Background Epoxyeicosatrienoic acids (EETs) are metabolites of arachidonic acid with multiple biological functions. Rodent experiments suggest EETs play a role in insulin sensitivity and diabetes, but evidence in humans is limited. To address this kn
Autor:
Daniel I. Chasman, Torben Hansen, Rebecca S. Fine, Kari E. North, Harald Grallert, Jeffrey Haesser, Jie Yao, Arund D. Pradhan, Peter Kovacs, Mariaelisa Graff, Rebecca D. Jackson, Zoltán Kutalik, James G. Wilson, Neil Robertson, Mika Kähönen, Linda S. Adair, Jennifer Kriebel, Ruth J. F. Loos, Massimo Mangino, Jayne F. Martin Carli, Yiying Zhang, M. Arfan Ikram, Paraskevi Christofidou, Linda Broer, Paul M. Ridker, Barbara McKnight, Satu Männistö, Sophia Metz, Tea Skaaby, Jette Bork-Jensen, Craig E. Pennell, Sophie Molnos, Michael A. Province, Xiuqing Guo, Laura B. L. Wittemans, Stephen J. Lye, Cornelia M. van Duijn, Samuli Ripatti, Ko Willems van Dijk, Tim Kacprowski, America A. Sandoval-Zárate, Hermina Jakupović, Tuomas O. Kilpeläinen, Michael Preuss, Jaeyoung Hong, Cristina Venturini, Ying Wu, Germán D. Carrasquilla, Ivana Prokic, Mary F. Feitosa, Melissa E. Garcia, Paul L. Auer, Leslie A. Lange, Leo-Pekka Lyytikäinen, Kristin L. Young, Tugce Karaderi, Alexander P. Reiner, Tim D. Spector, Anubha Mahajan, Claudia Schurmann, Jerome I. Rotter, Rudolph L. Leibel, Georg Homuth, Claudia A. Doege, Hakon Hakonarson, Nicholas J. Wareham, Najaf Amin, Shuai Wang, Matthias Blüher, Ayse Demirkan, Andrew P. Morris, Charles A. LeDuc, Claudia Langenberg, Hanieh Yaghootkar, Mike A. Nalls, Erik Ingelsson, Dennis O. Mook-Kanamori, Jorge R. Kizer, Carolina Medina-Gomez, Timothy M. Frayling, Colleen M. Sitlani, David A. Mackey, Bruce M. Psaty, Matthias Nauck, Struan F.A. Grant, Konstantin Strauch, Olli T. Raitakari, Alexander Teumer, Mark Walker, Jonathan P. Bradfield, Judith B. Borja, Karen L. Mohlke, Lars Lind, André G. Uitterlinden, Renée de Mutsert, Ruifang Li-Gao, Cassandra N. Spracklen, Jin Li, Anne E. Justice, Cecilia M. Lindgren, Kaiying Guo, Terho Lehtimäki, Pekka Jousilahti, Yingchang Lu, Yii-Der Ida Chen, Sara M. Willems, Tamara B. Harris, Matthew A. Allison, Carol A. Wang, Niels Grarup, Lam Opal Huang, Veikko Salomaa, Jian'an Luan, Robert A. Scott, Kent D. Taylor, James B. Meigs
Publikováno v:
Diabetes 69, 2806-2818 (2020)
Diabetes
Diabetes, 69(12), 2806-2818. American Diabetes Association Inc.
Diabetes, 69(12), 2806-2818. AMER DIABETES ASSOC
Diabetes
Diabetes, 69(12), 2806-2818. American Diabetes Association Inc.
Diabetes, 69(12), 2806-2818. AMER DIABETES ASSOC
Leptin influences food intake by informing the brain about the status of body fat stores. Rare LEP mutations associated with congenital leptin deficiency cause severe early-onset obesity that can be mitigated by administering leptin. However, the rol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6056048ee9ce66a1bc8a8aa0d18726c
https://hdl.handle.net/1887/3182375
https://hdl.handle.net/1887/3182375