Zobrazeno 241 - 250
of 779
pro vyhledávání: '"Aviv Regev"'
Autor:
Aviv Regev, Tzofia Glikman, Ittai Ben-Porath, Yuval Nevo, Yael Gabai, Reba Condiotti, Roy Z. Granit, Federica Piccioni, Ulrich Lehmann, Einat Carmon, David E. Root, Keren Paz, Amir Sonnenblick, Tamar Sella, Tamar Peretz, Eitan Winter, Hadas Masury, Simona Dalin, Yaakov Fixler
Publikováno v:
Elsevier
Cell Reports, Vol 24, Iss 12, Pp 3237-3250 (2018)
Cell Reports, Vol 24, Iss 12, Pp 3237-3250 (2018)
Summary: Differentiation events contribute to phenotypic cellular heterogeneity within tumors and influence disease progression and response to therapy. Here, we dissect mechanisms controlling intratumoral heterogeneity within triple-negative basal-l
Autor:
Stephen J. Fleming, Bo Li, Mehrtash Babadi, Katherine J. Siddle, Donald E. Ingber, Alexandra-Chloé Villani, Pritha Sen, Adam Essene, Marty Ross, Kushal K. Dey, Yiming Yang, Shamsudheen K. Vellarikkal, Olga R. Brook, Isaac H. Solomon, Phylicia Dorceus, Siddharth S. Raju, Tyler Hether, Sebastian Niezen, Dan Zollinger, Alexander Sturm, Pardis C. Sabeti, Purushothama Rao Tata, Yury Popov, Timothy L. Tickle, Ioannis S. Vlachos, Carly G. K. Ziegler, Jonathan L. Hecht, Z. Gordon Jiang, Winston Hide, James R. Stone, Rajat M. Gupta, Linus T.-Y. Tsai, Sarah Warren, Jesse M. Engreitz, Jonathan H. Chen, Victoria M. Tran, Michael Leney-Greene, Daniel T. Montoro, Michelle Siciliano, Asa Segerstolpe, Graham Heimberg, Pourya Naderi, Stefan Riedel, Alkes L. Price, Lisa A. Cosimi, Tyler Harvey, Toni Delorey, Prajan Divakar, Deborah T. Hung, Malika Sud, Joshua Gould, Rachelly Normand, Shuting Zhang, Orit Rozenblatt-Rosen, Ayshwarya Subramanian, Donna M. Fitzgerald, Steven Gazal, Devan Phillips, Cristin McCabe, Joseph M. Beechem, Nick Barkas, Erroll H. Rueckert, Dejan Juric, Hui Ma, Jason Reeves, Ellen Todres, Orr Ashenberg, Domenic Abbondanza, Alex K. Shalek, Liuliu Pan, Erica Normandin, Caroline B. M. Porter, Mari Niemi, Samouil L. Farhi, Robert S. Rogers, Deepti Pant, Gyongyi Szabo, Yered Pita-Juárez, Liat Amir-Zilberstein, Melissa Rudy, Christoph Muus, Christopher J. Pinto, Andrea Ganna, Aviv Regev, Robin Fropf, Michal Slyper, Richard M. Novak, Daniel E. McLoughlin, Jenna Pfiffner-Borges, Robert F. Padera, Eric M. Miller, Jayaraj Rajagopal, Avinash Waghray, Nir Hacohen, Karthik A. Jagadeesh, Judit Jané-Valbuena, James Gomez, Zohar Bloom-Ackermann
Publikováno v:
bioRxiv
The SARS-CoV-2 pandemic has caused over 1 million deaths globally, mostly due to acute lung injury and acute respiratory distress syndrome, or direct complications resulting in multiple-organ failures. Little is known about the host tissue immune and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43a261ef5f1b07087db03ed09fb065f0
https://europepmc.org/articles/PMC7924267/
https://europepmc.org/articles/PMC7924267/
Autor:
Eeshit Dhaval Vaishnav, Carl G. de Boer, Moran Yassour, Jennifer Molinet, Lin Fan, Xian Adiconis, Dawn A. Thompson, Francisco A. Cubillos, Joshua Z. Levin, Aviv Regev
Mutations in non-coding cis-regulatory DNA sequences can alter gene expression, organismal phenotype, and fitness. Fitness landscapes, which map DNA sequence to organismal fitness, are a long-standing goal in biology, but have remained elusive becaus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e12dca381dbff8110d549bacfc72cdbf
https://doi.org/10.1101/2021.02.17.430503
https://doi.org/10.1101/2021.02.17.430503
Autor:
Sara Napolitano, Jingyi Wu, Michal Slyper, Sébastien Vigneau, Asaf Rotem, Bruce Johnson, Orit Rozenblatt-Rosen, Aviv Regev
This protocol was used for the dissociation of human neuroblastoma resections to a single-cell suspension compatible with droplet-based single-cell RNA-Seq technology for the Human Tumor Atlas Pilot Project. For processing human neuroblastoma tumors,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::63fe31977b1e4ad58dc67f8f8ee8673f
https://doi.org/10.17504/protocols.io.brvnm65e
https://doi.org/10.17504/protocols.io.brvnm65e
Autor:
David DeTomaso, Yvonne C. Lee, Ana C. Anderson, Vijay K. Kuchroo, Nir Yosef, Patrick R. Burkett, Danielle Dionne, Antonia Wallrapp, Meyer zu Horste G, Aviv Regev, Ramnik J. Xavier, Jackson Nyman, Chao Wang, Mathias Pawlak, Samantha J. Riesenfeld
SummaryThe cytokine receptor IL-23R plays a fundamental role in inflammation and autoimmunity. However, several observations have been difficult to reconcile under the assumption that only Th17 cells critically depend on IL-23 to acquire a pathogenic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc05cb90675c3d4c9d0f53a8647add49
https://doi.org/10.1101/2021.01.24.426445
https://doi.org/10.1101/2021.01.24.426445
Autor:
David Artis, Hattie Chung, Bertrand Z. Yeung, Julia Waldman, Christopher N. Parkhurst, Aviv Regev, Ehsan Habibi, Emma M. Magee, Devan Phillips, Fei Chen
Identifying gene regulatory targets of nuclear proteins in tissues remains a challenge. Here we describe intranuclear Cellular Indexing of Transcriptomes and Epitopes (inCITE-seq), a scalable method for measuring multiplexed intranuclear protein leve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71e3035d0112fac1478cc239f8c4f5fd
https://doi.org/10.1101/2021.01.18.427139
https://doi.org/10.1101/2021.01.18.427139
Autor:
Bertrand Z. Yeung, David Artis, Christopher N. Parkhurst, Emma M. Magee, Ehsan Habibi, Julia Waldman, Aviv Regev, Hattie Chung, Devan Phillips, Fei Chen
Publikováno v:
Nat Methods
Identifying gene-regulatory targets of nuclear proteins in tissues is a challenge. Here we describe intranuclear cellular indexing of transcriptomes and epitopes (inCITE-seq), a scalable method that measures multiplexed intranuclear protein levels an
Autor:
Sarah E. Blatt, Izumi de los Rios Kobara, Aviv Regev, Arjun Bhutkar, David Canner, Sandro Santagata, Sara Z. Tavana, Amy Li, Jason M. Schenkel, Tyler Jacks, Grace E. Crossland, Michelle Hillman, Tamina Kienka, Peter M. K. Westcott, Andrea Garmilla, Giorgio Gaglia, William L. Hwang, Megan L. Burger, Cecily C. Ritch, Amanda M. Cruz
Publikováno v:
SSRN Electronic Journal.
CD8 T cell responses against different tumor neoantigens occur simultaneously, yet little is known about their interplay and its impact on T cell function and tumor control. In mouse lung adenocarcinoma, we find that immunodominance is established in
Autor:
Anna Hupalowska, Aviv Regev, Human Cell Atlas Standards, Jay W. Shin, Holger Heyn, Jennifer Rood, Orit Rozenblatt-Rosen
Publikováno v:
Nature Biotechnology
Autor:
Jennifer E. Towne, Toru Nakata, Ariel Lefkovith, Chih Hung Chou, Ramnik J. Xavier, Aviv Regev, Lingfei Wang, Daniel B. Graham, Kai Liu, Junmei Yao, Alok Jaiswal, Kwontae You, Jacqueline Perrigoue, Abdifatah S. Omar
Publikováno v:
Science
Transcriptional control of proteostasis Tissue homeostasis requires the coordinated activity of multiple cell types to initiate and then resolve inflammation. Intrinsic cellular stress-response pathways facilitate adaptation to stress and tissue rest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b91fbf3e3013e227bf82e52d8669a9f4
https://europepmc.org/articles/PMC8315080/
https://europepmc.org/articles/PMC8315080/