Zobrazeno 241 - 250
of 600
pro vyhledávání: '"Anna Mae Diehl"'
Autor:
Stephen O. Crawford, Jeanne M. Clark, Anna Mae Diehl, Susanne Hemker, Charalett E. Diggs, Frederick L. Brancati, Steven F. Solga, Alena Horská
Publikováno v:
Liver International. 28:675-681
Hepatic magnetic resonance spectroscopy (MRS) is increasingly being applied to many areas of patient-oriented liver research (1). Proton MRS (1H MRS) can quantify triglyceride content in the liver (2) and has become well-established for this purpose
Autor:
Susanne V Fleig, Kevin Brown, Hua Mao, Jason K. Sicklick, Ying Wang, Liu Yang, Anna Mae Diehl, Alessia Omenetti, Yin-Xiong Li
Publikováno v:
Journal of Hepatology. 48:98-106
Background/Aims Factors released during liver injury, such as platelet derived growth factor-BB (PDGF), promote accumulation of myofibroblastic hepatic stellate cells (MFB) that drive the pathogenesis of cirrhosis. The hedgehog (Hh) pathway regulates
Autor:
Hendrika M.A. VanDongen, Susanne V Fleig, Liu Yang, Anna Mae Diehl, Steve S. Choi, Jiawen Huang, Jason K. Sicklick, Alessia Omenetti, Youngmi Jung
Publikováno v:
Laboratory Investigation. 87:1227-1239
Progenitors regenerate fatty livers but the mechanisms involved are uncertain. The Hedgehog pathway regulates mesendodermal progenitors and modulates mesenchymal-epithelial interactions during tissue remodeling. To determine if Hedgehog signaling inc
Autor:
Anna Mae Diehl, Manal F. Abdelmalek
Publikováno v:
Medical Clinics of North America. 91:1125-1149
Nonalcoholic fatty liver disease (NAFLD) refers to a spectrum of liver damage ranging from simple steatosis to nonalcoholic steatohepatitis, advanced fibrosis, and rarely, progression to cirrhosis. The pathogenesis of NAFLD is thought to be related t
Autor:
Anna Mae Diehl, S R Smith, F L Brancati, Alena Horská, Pinaki Ghosh, Stephen O. Crawford, Steven F. Solga, Susanne Bonekamp, Jeanne M. Clark
Publikováno v:
International Journal of Obesity. 32:100-111
To examine five available software packages for the assessment of abdominal adipose tissue with magnetic resonance imaging, compare their features and assess the reliability of measurement results. Feature evaluation and test–retest reliability of
Autor:
Shannon J. McCall, Ayako Suzuki, Jason K. Sicklick, Jiawen Huang, Liu Yang, Yin-Xiong Li, Anna Mae Diehl, Steve S. Choi, Youngmi Jung, Alessia Omenetti
Publikováno v:
Laboratory Investigation. 87:499-514
In bile duct-ligated (BDL) rodents, as in humans with chronic cholangiopathies, biliary obstruction triggers proliferation of bile ductular cells that are surrounded by fibrosis produced by adjacent myofibroblastic cells in the hepatic mesenchyme. Th
Publikováno v:
Hepatology. 45:1091-1096
Indian Hedgehog (Ihh) regulates tissue morphogenesis. Hedgehog (Hh) activity has been demonstrated in human cholangiocarcinoma and hepatocellular carcinoma lines, and in myofibroblasts and progenitors from adult rodent livers. We evaluated Hh pathway
Autor:
Sanjay Bhanot, Sanjay K. Pandey, Liu Yang, Jiawen Huang, Xing Xian Yu, Yin-Xiong Li, Brett P. Monia, Shannon J. McCall, Anna Mae Diehl, Kanji Yamaguchi
Publikováno v:
Hepatology. 45:1366-1374
In the early stages of nonalcoholic fatty liver disease (NAFLD), triglycerides accumulate in hepatocytes. Diacylglycerol acyltransferase 2 (DGAT2) catalyzes the final step in hepatocyte triglyceride biosynthesis. DGAT2 antisense oligonucleotide (ASO)
Autor:
Ruixin, Zhu, Susan S, Baker, Cynthia A, Moylan, Manal F, Abdelmalek, Cynthia D, Guy, Fausto, Zamboni, Dingfeng, Wu, Weili, Lin, Wensheng, Liu, Robert D, Baker, Sugantha, Govindarajan, Zhiwei, Cao, Patrizia, Farci, Anna Mae, Diehl, Lixin, Zhu
Publikováno v:
The Journal of pathology. 238(4)
Obese animals and non-alcoholic fatty liver disease (NAFLD) patients exhibit elevated blood alcohol, suggesting potential contributions of alcohol metabolism to the development of NAFLD. Liver gene expression in patients with biopsy-proven mild (N =
Publikováno v:
Science bulletin. 60(8)
Initiation and progression of hepatocellular carcinoma (HCC) is intimately associated with a chronically diseased liver tissue. This diseased liver tissue background is a drastically different microenvironment from the healthy liver, especially with