Zobrazeno 21 - 30
of 600
pro vyhledávání: '"Anna Mae Diehl"'
Publikováno v:
JCI Insight, Vol 5, Iss 22 (2020)
Adult liver has enormous regenerative capacity; it can regenerate after losing two-thirds of its mass while sustaining essential metabolic functions. How the liver balances dual demands for increased proliferative activity with maintenance of organ f
Externí odkaz:
https://doaj.org/article/dcda33acc6254bc694933c95496be6d5
Autor:
Ko Maung, Sendhilnathan Ramalingam, Mohammad Chaudhry, Yi Ren, Sin-Ho Jung, Kristi Romero, Kelly Corbet, Nelson J Chao, Taewoong Choi, Anna Mae Diehl, Louis Diehl, Cristina Gasparetto, Mitchell Horwitz, Gwynn Douglas Long, Richard D Lopez, David A Rizzieri, Stefanie Sarantopoulos, Keith M Sullivan, Mustafa R Bashir, Anthony D Sung
Publikováno v:
PLoS ONE, Vol 15, Iss 9, p e0238824 (2020)
Allogeneic-HCT (allo-HCT), while potentially curative, can result in significant complications including graft versus host disease (GVHD). Prior studies suggest that metabolic syndrome may be one risk factor for GVHD. We hypothesized that hepatic ste
Externí odkaz:
https://doaj.org/article/ebf9b78ac6c540739ed63938ecd872d4
Autor:
Sihyung Wang, Youngmi Jung, Jeongeun Hyun, Matthew Friedersdorf, Seh-Hoon Oh, Jieun Kim, Richard T. Premont, Jack D. Keene, Anna Mae Diehl
Publikováno v:
Cellular Physiology and Biochemistry, Vol 48, Iss 3, Pp 1215-1229 (2018)
Background/Aims: Myofibroblasts (MF) derived from quiescent nonfibrogenic hepatic stellate cells (HSC) are the major sources of fibrous matrix in cirrhosis. Because many factors interact to regulate expansion and regression of MF-HSC populations, eff
Externí odkaz:
https://doaj.org/article/79865b208d884ea78ffe5ee0a26e1ad6
Autor:
Firas Alhasson, Ratanesh Kumar Seth, Sutapa Sarkar, Diana A. Kimono, Muayad S. Albadrani, Diptadip Dattaroy, Varun Chandrashekaran, Geoffrey I. Scott, Samir Raychoudhury, Mitzi Nagarkatti, Prakash Nagarkatti, Anna Mae Diehl, Saurabh Chatterjee
Publikováno v:
Redox Biology, Vol 17, Iss , Pp 1-15 (2018)
High circulatory insulin and leptin followed by underlying inflammation are often ascribed to the ectopic manifestations in non-alcoholic fatty liver disease (NAFLD) but the exact molecular pathways remain unclear. We have shown previously that CYP2E
Externí odkaz:
https://doaj.org/article/74b238fabfc549c98d1cd9024c69439c
Autor:
Varun Chandrashekaran, Ratanesh K. Seth, Diptadip Dattaroy, Firas Alhasson, Jacek Ziolenka, James Carson, Franklin G. Berger, Balaraman Kalyanaraman, Anna Mae Diehl, Saurabh Chatterjee
Publikováno v:
Redox Biology, Vol 13, Iss C, Pp 8-19 (2017)
Recent clinical studies found a strong association of colonic inflammation and Inflammatory bowel disease (IBD)-like phenotype with NonAlcoholic Fatty liver Disease (NAFLD) yet the mechanisms remain unknown. The present study identifies high mobility
Externí odkaz:
https://doaj.org/article/24e8fd36be8c4ea0a6d7358176b07182
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 3, Pp 1147-1148 (2021)
Externí odkaz:
https://doaj.org/article/b280c7fe7f794ac2afd925ffb51e195b
Autor:
Jieun Kim, Jeongeun Hyun, Sihyung Wang, Chanbin Lee, Jae-Wook Lee, Eun-Yi Moon, Heejae Cha, Anna Mae Diehl, Youngmi Jung
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-16 (2017)
Abstract The molecular mechanisms of thymosin beta-4 (TB4) involved in regulating hepatic stellate cell (HSC) functions remain unclear. Therefore, we hypothesize that TB4 influences HSC activation through hedgehog (Hh) pathway. HSC functions declined
Externí odkaz:
https://doaj.org/article/de1193bb16be4930b317ead645d89755
Autor:
Guanhua Xie, Marzena Swiderska-Syn, Mark L. Jewell, Mariana Verdelho Machado, Gregory A. Michelotti, Richard T. Premont, Anna Mae Diehl
Publikováno v:
BMC Cell Biology, Vol 18, Iss 1, Pp 1-14 (2017)
Abstract Background Obesity is associated with multiple diseases, but it is unclear how obesity promotes progressive tissue damage. Recovery from injury requires repair, an energy-expensive process that is coupled to energy availability at the cellul
Externí odkaz:
https://doaj.org/article/70df0e0af0644f11afbd602365a23c5f
Autor:
Kara Wegermann, Ricardo Henao, Anna Mae Diehl, Susan K Murphy, Manal F Abdelmalek, Cynthia A Moylan
Publikováno v:
PLoS ONE, Vol 13, Iss 9, p e0204308 (2018)
BACKGROUND AND OBJECTIVES:Although the burden of non-alcoholic fatty liver disease (NAFLD) continues to increase worldwide, genetic factors predicting progression to cirrhosis and decompensation in NAFLD remain poorly understood. We sought to determi
Externí odkaz:
https://doaj.org/article/caba766bc364413c8f5cba9619c0a480
Autor:
Thiago Almeida Pereira, Wing-Kin Syn, Frederico Figueiredo Amâncio, Pedro Henrique Diniz Cunha, Julia Fonseca Morais Caporali, Guilherme Vaz de Melo Trindade, Elisângela Trindade Santos, Márcia Maria Souza, Zilton Araújo Andrade, Rafal P Witek, William Evan Secor, Fausto Edmundo Lima Pereira, José Roberto Lambertucci, Anna Mae Diehl
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 10, Iss 10, p e0005057 (2016)
Symptomatic acute schistosomiasis mansoni is a systemic hypersensitivity reaction against the migrating schistosomula and mature eggs after a primary infection. The mechanisms involved in the pathogenesis of acute schistosomiasis are not fully elucid
Externí odkaz:
https://doaj.org/article/87e6146f05e549bbb4c479640be480d8