Zobrazeno 11 - 20
of 617
pro vyhledávání: '"Angelo M. De Marzo"'
Autor:
Jack Mottahedeh, Michael C. Haffner, Tristan R. Grogan, Takao Hashimoto, Preston D. Crowell, Himisha Beltran, Andrea Sboner, Rohan Bareja, David Esopi, William B. Isaacs, Srinivasan Yegnasubramanian, Matthew B. Rettig, David A. Elashoff, Elizabeth A. Platz, Angelo M. De Marzo, Michael A. Teitell, Andrew S. Goldstein
Publikováno v:
Cancer & Metabolism, Vol 6, Iss 1, Pp 1-17 (2018)
Abstract Background Cancer cell metabolism requires sustained pools of intracellular nicotinamide adenine dinucleotide (NAD+) which is maintained by a balance of NAD+ hydrolase activity and NAD+ salvage activity. We recently reported that human prost
Externí odkaz:
https://doaj.org/article/74edf0c78aa84fd28034f0b9a6de4892
Autor:
Binod Kumar, Avi Z. Rosenberg, Su Mi Choi, Karen Fox-Talbot, Angelo M. De Marzo, Larisa Nonn, W. Nathaniel Brennen, Luigi Marchionni, Marc K. Halushka, Shawn E. Lupold
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Abstract MiR-1 and miR-143 are frequently reduced in human prostate cancer (PCa), while miR-141 and miR-21 are frequently elevated. Consequently, these miRNAs have been studied as cell-autonomous tumor suppressors and oncogenes. However, the cell-typ
Externí odkaz:
https://doaj.org/article/6a8d5bc00c9b474db0d4de545fbb6069
Autor:
Cornelia Peterson, Robert Moore, Jessica L. Hicks, Laura A. Morsberger, Angelo M. De Marzo, Ying Zou, Charles G. Eberhart, Ashley A. Campbell
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 16, p 8454 (2021)
Ocular adnexal (OA) sebaceous carcinomas generally demonstrate more aggressive clinical and histopathological phenotypes than extraocular cases, but the molecular drivers implicated in their oncogenesis remain poorly defined. A retrospective review o
Externí odkaz:
https://doaj.org/article/c0f0d587b7794b68b19c6d4dea9f114c
Autor:
Michael C. Haffner, David M. Esopi, Alcides Chaux, Meltem Gürel, Susmita Ghosh, Ajay M. Vaghasia, Harrison Tsai, Kunhwa Kim, Nicole Castagna, Hong Lam, Jessica Hicks, Nicolas Wyhs, Debika Biswal Shinohara, Paula J. Hurley, Brian W. Simons, Edward M. Schaeffer, Tamara L. Lotan, William B. Isaacs, George J. Netto, Angelo M. De Marzo, William G. Nelson, Steven S. An, Srinivasan Yegnasubramanian
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-17 (2017)
Invasion of malignant cells involves changes in cytoskeleton dynamics. Here the authors identify absent in melanoma 1 as an actin binding protein and show that it regulates cytoskeletal remodeling and cell migration in prostate epithelial cells, acti
Externí odkaz:
https://doaj.org/article/41b0a231505343d098eefebb391e055f
Autor:
Kirstie Canene-Adams, Karen S. Sfanos, Chung-Tiang Liang, Srinivasan Yegnasubramanian, William G. Nelson, Cory Brayton, Angelo M. De Marzo
Publikováno v:
PLoS ONE, Vol 9, Iss 1 (2014)
Externí odkaz:
https://doaj.org/article/ef995220b30f448fbe3e68f554af8956
Autor:
Bruce J. Trock, Yuezhou Jing, Brent Mabey, Zaina Sangale, Lauren Lenz, Nora Haney, Igor Vidal, Stephanie A. Glavaris, Gunes Guner, Onur Ertunc, Ibrahim Kulac, Javier A. Baena Del Valle, Tracy Jones, Misop Han, Alan W. Partin, Todd Cohen, Steven Stone, Angelo M. De Marzo
Publikováno v:
Journal of Urology. 208:1182-1193
The prognostic value for metastasis of the cell-cycle progression score and phosphatase and tensin homolog haven't been evaluated jointly in contemporary men with exclusively intermediate- or high-risk prostate cancer. We evaluated associations of ce
Autor:
Hasim Bakbak, Erolcan Sayar, Harsimar B. Kaur, Daniela C. Salles, Radhika A. Patel, Jessica Hicks, Tamara L. Lotan, Angelo M. De Marzo, Roman Gulati, Jonathan I. Epstein, Michael C. Haffner
Publikováno v:
Human Pathology. 130:18-24
Genomic studies have demonstrated a high level of intra-tumoral heterogeneity in prostate cancer. There is strong evidence suggesting that individual tumor foci can arise as genetically distinct, clonally independent lesions. However, recent studies
Autor:
Janielle P. Maynard, Taylor N. Godwin, Jiayun Lu, Igor Vidal, Tamara L. Lotan, Angelo M. De Marzo, Corinne E. Joshu, Karen S. Sfanos
Publikováno v:
The Prostate. 82:1505-1519
Black men are two to three times more likely to die from prostate cancer (PCa) than White men. This disparity is due in part to discrepancies in socioeconomic status and access to quality care. Studies also suggest that differences in the prevalence
Autor:
Radhika A. Patel, Ilsa Coleman, Martine P. Roudier, Eric Q. Konnick, Brian Hanratty, Ruth Dumpit, Jared M. Lucas, Lisa S. Ang, Jin-Yih Low, Maria S. Tretiakova, Gavin Ha, John K. Lee, Lawrence D. True, Angelo M. De Marzo, Peter S. Nelson, Colm Morrissey, Colin C. Pritchard, Michael C. Haffner
Publikováno v:
Cancer Res Commun
Anaplastic lymphoma kinase (ALK) is a tyrosine kinase with genomic and expression changes in many solid tumors. ALK inhibition is the first-line therapy for lung cancers with ALK alterations, and an effective therapy in other tumor types, but has not
Autor:
Onur Ertunc, Erica Smearman, Qizhi Zheng, Jessica L. Hicks, Jacqueline A. Brosnan-Cashman, Tracy Jones, Carolina Gomes-Alexandre, Levent Trabzonlu, Alan K. Meeker, Angelo M. De Marzo, Christopher M. Heaphy
Telomeres are terminal chromosomal elements that are essential for the maintenance of genomic integrity. The measurement of telomere content provides useful diagnostic and prognostic information, and fluorescent methods have been developed for this p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ef1a1ba0a18aa40f37adf6313ce02f2
https://doi.org/10.1101/2023.04.04.535575
https://doi.org/10.1101/2023.04.04.535575