Zobrazeno 91 - 100
of 385
pro vyhledávání: '"Andres J. Klein-Szanto"'
Autor:
Timothy Ito, Andres J. Klein-Szanto, Jinfei Xu, Joseph R. Testa, David L. Wiest, Suraj Peri, Eleonora Sementino, Zemin Liu, Yinfei Tan, Kathy Q. Cai, Jianming Pei
Publikováno v:
Oncotarget
// Yinfei Tan 1, * , Eleonora Sementino 1, * , Jinfei Xu 1 , Jianming Pei 1 , Zemin Liu 1 , Timothy K. Ito 1 , Kathy Q. Cai 2 , Suraj Peri 3 , Andres J.P. Klein-Szanto 1, 2 , David L. Wiest 4 , Joseph R. Testa 1 1 Cancer Biology Program, Fox Chase Ca
Publikováno v:
Molecular Carcinogenesis. 56:1182-1188
Proprotein convertases (PCs) are serine proteases with an active role in the post-translational processing of numerous inactive proteins to active proteins including many substrates of paramount importance in cancer development and progression. Furin
Autor:
Jennifer R. Pyle, V. Craig Jordan, Andres J. Klein-Szanto, Helen Kim, Joan S. Lewis-Wambi, Chris Wambi, Roshani R. Patel
Publikováno v:
Breast Cancer Research, Vol 20, Iss 1, Pp 1-3 (2018)
Breast Cancer Research : BCR
Breast Cancer Research : BCR
Introduction Estrogen deprivation using aromatase inhibitors is one of the standard treatments for postmenopausal women with estrogen receptor (ER)-positive breast cancer. However, one of the consequences of prolonged estrogen suppression is acquired
Autor:
Edison Mejia, Miguel Garcia-Diaz, Jeelan Basha, Hiroshi Nakagawa, Eric F. Rappaport, Andres J. Klein-Szanto, Narayan G. Avadhani, Tapas K. Kundu, Satish Srinivasan, Ji-Kang Fang, Kip E. Guja, Manti Guha, Gordon Ruthel, Brett A. Kaufman, F. Brad Johnson, M. Rebecca Glineburg
Publikováno v:
Cell Discovery
Cell Discovery, Vol 5, Iss 1, Pp 1-1 (2019)
Cell Discovery, Vol 5, Iss 1, Pp 1-1 (2019)
Reduced mitochondrial DNA copy number, mitochondrial DNA mutations or disruption of electron transfer chain complexes induce mitochondria-to-nucleus retrograde signaling, which induces global change in nuclear gene expression ultimately contributing
Autor:
Ashley A. Lento, Hiroshi Nakagawa, Kensuke Suzuki, Qiaosi Tang, Mirazul Islam, Adam J. Bass, Anil K. Rustgi, Veronique Giroux, Gizem Efe, Apple Long, E. Paul Wileyto, Tatiana A. Karakasheva, Andres J. Klein-Szanto
Publikováno v:
EMBO Rep
Esophageal squamous cell carcinoma (ESCC) is the most common subtype of esophageal cancer worldwide. The most commonly mutated gene in ESCC is TP53. Using a combinatorial genetic and carcinogenic approach, we generate a novel mouse model of ESCC expr
Autor:
Andres J. Klein-Szanto, Javier S. Castresana, Daniel E. Bassi, Gary Thomas, Ricardo Lopez de Cicco, Javier Mercapide
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 25(8)
Purpose: Astrocytoma arises in the central nervous system as a tumorof great lethality, in part because of the invasive potential of the neoplastic cells that are able to release extracellular matrix-degrading enzymes. Furin convertase activates seve
Autor:
Anna-Mariya, Kukuyan, Eleonora, Sementino, Yuwaraj, Kadariya, Craig W, Menges, Mitchell, Cheung, Yinfei, Tan, Kathy Q, Cai, Michael J, Slifker, Suraj, Peri, Andres J, Klein-Szanto, Frank J, Rauscher, Joseph R, Testa
Publikováno v:
Cancer research. 79(16)
Pleural malignant mesothelioma (MM) is a therapy-resistant cancer affecting the serosal lining of the thoracic cavity. Mutations/deletions of BAP1, CDKN2A, and NF2 are the most frequent genetic lesions in human MM. We introduced various combinations
Autor:
Jeffrey J Headd, Kathy N. Williams, Jacqueline B Plesset, Ashley A. Lento, Rosemarie Mick, Andres J. Klein-Szanto, Priya Chatterji, Rei Mizuno, Anil K. Rustgi, Sarah F. Andres, Kathryn E. Hamilton
Publikováno v:
Carcinogenesis
The RNA-binding protein insulin-like growth factor 2 mRNA binding protein 1 (IMP1) is overexpressed in colorectal cancer (CRC); however, evidence for a direct role for IMP1 in CRC metastasis is lacking. IMP1 is regulated by let-7 microRNA, which bind
Autor:
Priya Chatterji, Shun Liang, Premal Shah, Kathryn E. Hamilton, Anil K. Rustgi, Philip Hicks, Christopher J. Lengner, Amanda T. Mah, Jason R. Pitarresi, H. R. Sagara Wijeratne, Laurianne Van Landeghem, Andres J. Klein-Szanto, Brian D. Gregory, Lauren Simon, Sarah F. Andres, Blair B. Madison, Shawn W. Foley, Rei Mizuno
RNA-binding proteins (RBPs) are expressed broadly during both development and malignant transformation, yet their mechanistic roles in epithelial homeostasis or as drivers of tumor initiation and progression are incompletely understood. Here we descr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55c9891451436aca7a5c710d79a14e7b
https://europepmc.org/articles/PMC6075153/
https://europepmc.org/articles/PMC6075153/
Autor:
Manti Guha, Prasanna M. Chandramouleeswaran, Andres J. Klein-Szanto, James Garifallou, Clementina Mesaros, Hiroshi Nakagawa, Renata Pellegrino da Silva, Ian A. Blair, Noah Engel, Eishi Noguchi, Joseph A. Baur, Masataka Shimonosono, Hakon Hakonarson, Uma M. Sachdeva, Gordon Ruthel, Michael Gonzalez, Shinya Ohashi, Hisatsugu Maekawa, Kelly A. Whelan, Sarmistha Mukherjee
Publikováno v:
BASE-Bielefeld Academic Search Engine
PLoS ONE
PLoS ONE, Vol 15, Iss 9, p e0239625 (2020)
PLoS ONE
PLoS ONE, Vol 15, Iss 9, p e0239625 (2020)
During alcohol consumption, the esophageal mucosa is directly exposed to high concentrations of ethanol (EtOH). We therefore investigated the response of normal human esophageal epithelial cell lines EPC1, EPC2 and EPC3 to acute EtOH exposure. While