Zobrazeno 91 - 100
of 261
pro vyhledávání: '"Andreas Suhrbier"'
Autor:
Rebecca L Johnston, Elizabeth Ahern, Thuy T. Le, Emily M. Cross, Amanda L. Bain, Andreas Suhrbier, Simon Phipps, Nicola Waddell, Sudha Rao, Michelle Melino, Lambros T. Koufariotis, Natasha Collinson, Kexin Yan, Wen Juan Tu, Nabila Seddiki, Daniel J. Rawle, Robert D. McCuaig, Jade K. Forwood, Sofiya Tsimbalyuk
Publikováno v:
Cell Discovery, Vol 7, Iss 1, Pp 1-2 (2021)
Cell Discovery
Cell Discovery
Treatment options for COVID-19 remain limited, especially during the early or asymptomatic phase. Here, we report a novel SARS-CoV-2 viral replication mechanism mediated by interactions between ACE2 and the epigenetic eraser enzyme LSD1, and its inte
Autor:
Andreas Suhrbier, Liesel Stassen, Gregor J. Devine, Cassie C. Jansen, B. M. C. Randika Wimalasiri-Yapa, Roberto A. Barrero, Laith Yakob, Alyssa T. Pyke, Louise M. Hafner, Francesca D. Frentiu, Wenbiao Hu, Elizabeth A. McGraw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4864afed2484026e1c4cb531b08310b9
https://doi.org/10.1098/rsob.200246/v2/response1
https://doi.org/10.1098/rsob.200246/v2/response1
The international SARS-CoV-2 pandemic has resulted in an urgent need to identify new anti-viral drugs for treatment of COVID-19 patients. The initial step to identifying potential candidates usually involves in vitro screening. Here we describe a sim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0bf4831158ab31719d58e87fa1efb998
https://doi.org/10.1101/2020.10.13.338541
https://doi.org/10.1101/2020.10.13.338541
Autor:
Shuxiong Chen, Benjamin Evert, Adetayo Adeniyi, Mercè Salla‐Martret, Linda H.‐L. Lua, Victoria Ozberk, Manisha Pandey, Michael F. Good, Andreas Suhrbier, Peter Halfmann, Yoshihiro Kawaoka, Bernd H. A. Rehm
Publikováno v:
Advanced Healthcare Materials. 11:2270017
Microplastic consumption induces inflammatory signatures in the colon and prolongs a viral arthritis
Autor:
Bing Tang, Andreas Suhrbier, Thuy T. Le, Cameron Bishop, Troy Dumenil, Daniel J. Rawle, Kexin Yan
Publikováno v:
Science of The Total Environment. 809:152212
Global microplastic (MP) contamination and the effects on the environment are well described. However, the potential for MP consumption to affect human health remains controversial. Mice consuming ≈80 µg/kg/day of 1 µm polystyrene MPs via their d
Autor:
Christopher Halliday, Kamil A. Sokolowski, Sophie Krumeich, David A. Elliott, Lynn Devilee, Sean J. Humphrey, Tobias Bald, Brian W.C. Tse, Gregory A. Quaife-Ryan, Leo J. Lee, Mark J. Smyth, David E. James, Rebecca L Johnston, Kanta Subbarao, Holly K. Voges, Richard J. Mills, Michael O. Sweeney, Liam T Reynolds, Stephen J. Nicholls, Mary Lor, Charley Mackenzie-Kludas, Li Fu, Jan Johansson, Kelli P. A. MacDonald, Partrick Rj Fortuna, Troy Dumenil, Norman C.W. Wong, Daniel J. Rawle, Brendan Griffen, Dad Abu-Bonsrah, Ellen Mathieson, Kathy Karavendzas, Neda R Mehdiabadi, Christian R. Engwerda, James E. Hudson, Rajeev Ruraraju, Dean Gilham, Andreas Suhrbier, Wei Zhao, Ewelina Kulikowski, Enzo R. Porrello, Simon R. Foster, Drew M. Titmarsh, Cameron Bishop, James H McMahon, Thuy T. Le
SUMMARYCardiac injury and dysfunction occur in COVID-19 patients and increase the risk of mortality. Causes are ill defined, but could be direct cardiac infection and/or inflammation-induced dysfunction. To identify mechanisms and cardio-protective d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d55141bf86d24196d81d19581a83309e
https://doi.org/10.1101/2020.08.23.258574
https://doi.org/10.1101/2020.08.23.258574
Autor:
Kexin Yan, Thuy T. Le, Liang Liu, Lesley-Ann Gray, Natalie A. Prow, Andreas Suhrbier, Paul Howley, John D. Hayball, Andrii Slonchak, Jessamine E. Hazlewood, Ann-Marie Patch, Troy Dumenil, Stephen H. Kazakoff, Daniel J. Rawle
Poxvirus systems have been extensively used as vaccine vectors. Herein a systems vaccinology analysis of intramuscular injection sites provides detailed insights into host innate immune responses, as well as expression of vector and recombinant immun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b5073a0f083977cd19a529bb5c234b3f
https://doi.org/10.1101/2020.08.17.254938
https://doi.org/10.1101/2020.08.17.254938
Autor:
Roberto A. Barrero, Laith Yakob, Francesca D. Frentiu, Elizabeth A. McGraw, Gregor J. Devine, Alyssa T. Pyke, Andreas Suhrbier, Wenbiao Hu, Liesel Stassen, Bmc Randika Wimalasiri-Yapa, Louise M. Hafner, Cassie C. Jansen
Arthropod-borne viruses (arboviruses) such as dengue, Zika and chikungunya constitute a significant proportion of the global disease burden. The principal vector of these pathogens is the mosquito Aedes (Ae.) aegypti, and its ability to transmit viru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca1a2a6f2b983c79f6a345d8e74d8a71
https://doi.org/10.1101/2020.07.31.230425
https://doi.org/10.1101/2020.07.31.230425
Autor:
Nias Y. G. Peng, Yin Xiang Setoh, Andreas Suhrbier, Andrew F. van den Hurk, Ernst J. Wolvetang, Kexin Yan, Francisco J. Torres, Alexander A. Khromykh, Leon E. Hugo, Alberto A. Amarilla, Gregor J. Devine, Morgan E. Freney, Sonja Hall-Mendelin, Harman Kaur Chaggar, Andrii Slonchak
Publikováno v:
Proceedings, Vol 50, Iss 112, p 112 (2020)
Similar to other flaviviruses, Zika virus (ZIKV) produces abundant subgenomic flavivirus RNA (sfRNA) derived from the 3’ untranslated region. The molecular mechanisms that determine the functions of sfRNA are currently not completely understood. He
Autor:
Julia A. Tree, Jerry Turnbull, Thuy T. Le, Tom Wilkinson, Courtney J. Mycroft-West, Michael J. Elmore, Julian D. J. Sng, Mark A. Skidmore, Tomas Bergström, Spalluto Cm, Yen-Hsi Chen, Alberto A. Amarilla, Mohit Chhabra, Joanna Said, Miles W. Carroll, Ed Yates, Yin Xiang Setoh, Richard Karlsson, Rebecca L. Miller, Scott E. Guimond, Naomi Coombes, Ieva Bagdonaite, Naphak Modhiran, Ferro, Zhang Yang, Marcelo A. Lima, Kristina Nyström, Edward Hammond, Paul R. Young, James P. Stewart, Edward Trybala, Humbert Mv, Karen R. Buttigieg, Keith Dredge, Daniel Watterson, Alexander A. Khromykh, Neha S. Gandhi, Andreas Suhrbier
SummaryHeparan sulfate (HS) is a cell surface polysaccharide recently identified as a co-receptor with the ACE2 protein for recognition of the S1 spike protein on SARS-CoV-2 virus, providing a tractable new target for therapeutic intervention. Clinic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1be82d6a29bf0b7edca98741aca12527
https://doi.org/10.1101/2020.06.24.169334
https://doi.org/10.1101/2020.06.24.169334