Zobrazeno 81 - 90
of 217
pro vyhledávání: '"Andreas Seeber"'
Autor:
Taofeek K. Owonikoko, Andrew Elliott, Bhakti Dwivedi, Andrey Ivanov, Gabriel Sica, Sonam Puri, Abdul Rafeh Naqash, Kathleen Claire Kerrigan, Shiven B. Patel, Andreas Seeber, Florian Kocher, Dipesh Uprety, Hirva Mamdani, Amit Kulkarni, Gilberto Lopes, Balazs Halmos, Wallace L. Akerley, Stephen V Liu, Wolfgang Michael Korn, Hossein Borghaei
Publikováno v:
Journal of Clinical Oncology. 40:8515-8515
8515 Background: Effective treatment options for SCLC remain limited and new treatment approaches are needed to improve outcome. We sought to validate the initial observation in cell lines and limited tissue samples of SCLC of a differential expressi
Autor:
Emil Lou, Nishant Gandhi, Alex Farrell, Joanne Xiu, Andreas Seeber, Shaalan Shaalan Beg, Minnu Monu, Sourat Darabi, Michael J. Demeure, Jim Abraham, Matthew James Oberley, John Marshall, Heloisa P. Soares
Publikováno v:
Journal of Clinical Oncology. 40:3071-3071
3071 Background: Targeted therapy of NENs based on the presence of SSTRs fills a unique niche in tumor biology and clinical treatment of patients with solid tumors. SSTRs have multiple isoforms and are collectively expressed in the majority of NENs.
Autor:
Emil Lou, Joanne Xiu, Yasmine Baca, Phillip Walker, Gulam Abbas Manji, Sepideh Gholami, Anwaar Saeed, Philip Agop Philip, Ajay Prakash, Igor A. Astsaturov, Greg Botta, Laith I. Abushahin, Davendra Sohal, Heinz-Josef Lenz, Anthony Frank Shields, Chadi Nabhan, Wafik S. El-Deiry, Andreas Seeber, Wolfgang Michael Korn
Publikováno v:
Journal of Clinical Oncology. 40:4142-4142
4142 Background: The composition of the tumor microenvironment (TME) in PDACs is more heavily driven by mutant (mt) KRAS than any other cancer. How genomic alterations of PDAC including KRAS status affect the immune cell (IC) landscape remains unclea
Autor:
Moh'd M. Khushman, Nishant Gandhi, Joanne Xiu, Bassel F. El-Rayes, Andreas Seeber, Grant Richard Williams, Darryl Alan Outlaw, Emil Lou, Anthony Frank Shields, Philip Agop Philip, Wafik S. El-Deiry, John Marshall, Priya Jayachandran, Heinz-Josef Lenz, Matthew James Oberley, Wolfgang Michael Korn, Upender Manne
Publikováno v:
Journal of Clinical Oncology. 40:3589-3589
3589 Background: In patients with colorectal cancers (CRCs), prior studies have reported that various TP53 mutations have prognostic significance. The anatomic location of the primary CRC and the TP53 mutation subtype influence patient survival. In t
Autor:
Sepideh Gholami, Yasmine Baca, Pavel Brodskiy, Joanne Xiu, Gulam Abbas Manji, Andreas Seeber, Anwaar Saeed, Benjamin Adam Weinberg, Moh'd M. Khushman, Rachna T. Shroff, Jim Abraham, Anthony Frank Shields, Heinz-Josef Lenz, John Marshall, Wolfgang Michael Korn, Emil Lou
Publikováno v:
Journal of Clinical Oncology. 40:3546-3546
3546 Background: CXC-chemokine receptor 4 (CXCR4) is a ubiquitous chemokine receptor activated by the CXCL12 ligand and is implicated in tumor invasion, metastasis, and immune cell (IC) trafficking. High CXCR4 expression is associated with poor progn
Autor:
Karan Pandya, Joanne Xiu, Alex Farrell, Michael J. Overman, Andreas Seeber, Jim Abraham, Anthony Frank Shields, Emil Lou, John Marshall, James L. Abbruzzese, Heinz-Josef Lenz, Wolfgang Michael Korn, Pat Gulhati
Publikováno v:
Journal of Clinical Oncology. 40:4018-4018
4018 Background: Small bowel adenocarcinoma (SBA) is a rare cancer with rising incidence and worse overall survival (OS) compared to other intestinal cancers. Clinical management of SBA is primarily extrapolated from colorectal cancer (CRC). Comprehe
Autor:
Andreas Seeber, Andrew Elliott, Jaime Modiano, Gerold Untergasser, Margaret von Mehren, Andrew Rosenberg, Moh'd Khushman, Don S. Dizon, Richard F. Riedel, Jonathan C. Trent, Kai Zimmer, Galina Lagos, Bradley DeNardo, Aaron Sarver, Alberto Puccini, Phillip Walker, Matthew James Oberley, Wolfgang Michael Korn, Domink Wolf, Florian Kocher
Publikováno v:
Journal of Clinical Oncology. 40:11525-11525
11525 Background: Osteosarcoma (OS) incidence is characterized by a bimodal age distribution, with peaks in early adolescence and in adults > 65 years of age. In contrast to adolescents, OS in adults is frequently considered as a secondary neoplasm (
Autor:
Renate Schaberl-Moser, Jakob M. Riedl, Konstantin Schlick, Arno Amann, Philipp J Jost, Richard Greil, Martin Pichler, Armin Gerger, Dominik A. Barth, Moritz Müller, Dominik Kiem, Florian Posch, Andreas Seeber, Lena Horvath, Michael Stotz
Publikováno v:
Therapeutic Advances in Medical Oncology
Therapeutic Advances in Medical Oncology, Vol 13 (2021)
Therapeutic Advances in Medical Oncology, Vol 13 (2021)
Background: The level of evidence for palliative second-line therapy in advanced esophageal squamous cell carcinoma (aESCC) is limited. This is the first study that reports efficacy data comparing second-line therapy + active symptom control (ASC) ve
Autor:
Diego Kauffmann-Guerrero, Arno Amann, Piotr Tymoszuk, Stefan Salcher, Florian Kocher, Florian Huemer, Gabriel Rinnerthaler, Dominik Wolf, Johannes Haybaeck, Sophia Daum, Amanda Tufman, Andreas Pircher, Andreas Seeber, Susanne Sprung
Publikováno v:
Lung cancer (Amsterdam, Netherlands). 159
Background The tumor-microenvironment (TME) represents an attractive therapeutic target in NSCLC and plays an important role for efficacy of cancer therapeutics. We hypothesized that upregulation of collagen synthesis might be associated with adverse
Autor:
Johannes Kerschbaumer, Florian Kocher, Stefan Schmidt, Dominik Wolf, Clemens Feistritzer, Andreas Seeber
Publikováno v:
Therapeutic Advances in Hematology
Therapeutic Advances in Hematology, Vol 12 (2021)
Therapeutic Advances in Hematology, Vol 12 (2021)
Patients with haemophilia A (HA) undergoing neurosurgical procedures have a high risk of haemorrhage with potential fatal outcome. Here, we present a successful perioperative haemostatic concept applying an extended half-life factor VIII (EHL FVIII),