Zobrazeno 31 - 40
of 296
pro vyhledávání: '"Andreas Link"'
Autor:
Sascha Grobe, Thomas Bayer, Emil Hamnevik, Sven Koban, Uwe T. Bornscheuer, Shuke Wu, Beatrice Großjohann, Christoph W. Grathwol, Christoffel P. S. Badenhorst, Andreas Link, Henrike Brundiek
Publikováno v:
Angewandte Chemie (International Ed. in English)
We engineered the cytochrome P450 monooxygenase CYP107D1 (OleP) from Streptomyces antibioticus for the stereo‐ and regioselective 7β‐hydroxylation of lithocholic acid (LCA) to yield ursodeoxycholic acid (UDCA). OleP was previously shown to hydro
Autor:
Christoffel P. S. Badenhorst, Uwe T. Bornscheuer, Shuke Wu, Beatrice Großjohann, Sven Koban, Thomas Bayer, Henrike Brundiek, Christoph W. Grathwol, Sascha Grobe, Emil Hamnevik, Andreas Link
Publikováno v:
Angewandte Chemie. 133:764-768
Autor:
Anna Nimmesgern, Niels Murawski, Sören L. Becker, Fabian K. Berger, Andreas Link, Sophie Roth, Philipp M. Lepper, Jörg Thomas Bittenbring
Publikováno v:
European Journal of Clinical Microbiology & Infectious Diseases
Invasive infections caused by carbapenemase-producing bacteria are associated with excess mortality. We applied a rapid diagnostic test (RDT) on clinical samples with an elevated likelihood of carbapenemase-producing bacteria and documented its impac
Autor:
Stephan, Pfister, Laura, Scherer, Anne-Marie, Boulay, Masaharu, Motoshita, Montserrat, Núñez, Mattia, Damiani, Manzardo, Alessandro, Jing, Huang, Andreas, Link, Jonas, Bunsen, Markus, Berger
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3657::d02b08b7679a6a6111478bbadceddf93
http://hdl.handle.net/11577/3444958
http://hdl.handle.net/11577/3444958
Global Characterization Factors for Quantifying Water Consumption Impacts on Freshwater Biodiversity
Autor:
ELEONORE PIERRAT, Valerio Barbarossa, Montserrat Núñez, Laura Scherer, Andreas Link, Mattia Daminani, Francesca Verones, Martin Dorber
Publikováno v:
SSRN Electronic Journal.
Publikováno v:
STAR Protocols, Vol 5, Iss 2, Pp 103005- (2024)
Summary: Isolating kidney tubules offers insights into their biological function without stroma, vascular cells, and immune system interference. Our murine tubule isolation protocol focuses on ex vivo cell death assays. We describe steps for solution
Externí odkaz:
https://doaj.org/article/3eb422cce0454481b6886eb40a3521de
Autor:
Christoph W. Grathwol, Klaus Weisz, Yoanes Maria Vianney, Andreas Link, Qingyun Tang, Ioannis V. Pavlidis, Uwe T. Bornscheuer
Publikováno v:
ChemCatChem. 12:3721-3727
Methylation of free hydroxyl groups is an important modification for flavonoids. It not only greatly increases absorption and oral bioavailability of flavonoids, but also brings new biological activities. Flavonoid methylation is usually achieved by
Autor:
Martin Roatsch, Andreas Link, Oxana Krylova, Udo Heinemann, Nicole Rüger, Manfred Jung, Piotr H. Małecki, Manfred S. Weiss
Publikováno v:
Małecki, P H, Rüger, N, Roatsch, M, Krylova, O, Link, A, Jung, M, Heinemann, U & Weiss, M S 2019, ' Structure-Based Screening of Tetrazolylhydrazide Inhibitors versus KDM4 Histone Demethylases ', ChemMedChem, vol. 14, no. 21, pp. 1828-1839 . https://doi.org/10.1002/cmdc.201900441
Chemmedchem
Chemmedchem
Human histone demethylases are known to play an important role in the development of several tumor types. Consequently, they have emerged as important medical targets for the treatment of human cancer. Herein, structural studies on tetrazolylhydrazid
Autor:
Christian Bock, Andreas Link, Robert K. Hofstetter, Werner Siegmund, Felix Potlitz, Abdrrahman Shemsu Surur, Georg M. Fassauer, Tobias Oergel, Christoph W. Grathwol, Mahmoud Hasan, Steven Behnisch
Publikováno v:
Journal of Chromatography A. 1603:338-347
Supercritical fluid chromatography (SFC) holds the potential to become an orthogonal method to HPLC/UHPLC in xenobiotic metabolism studies, due to its outstanding capacity to simultaneously separate highly similar (as HPLC) and physicochemically diff
Autor:
Robert K. Hofstetter, Andreas Link, Nathalie Wössner, Manfred Jung, Anja Bodtke, Adam C. Smith, Christoph W. Grathwol, Enrico Tapavicza, Sören Swyter
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 15, Iss 1, Pp 2170-2183 (2019)
Beilstein Journal of Organic Chemistry
Beilstein Journal of Organic Chemistry
The use of light as an external trigger to change ligand shape and as a result its bioactivity, allows the probing of pharmacologically relevant systems with spatiotemporal resolution. A hetero-stilbene lead resulting from the screening of a compound