Zobrazeno 241 - 250
of 328
pro vyhledávání: '"Agnieszka Wozniak"'
Autor:
Mariola Iliszko, Katarzyna Gawlik-Kuklinska, Maria Debiec-Rychter, Agnieszka Wozniak, Jolanta Wierzba, Mirosława Dubaniewicz-Wybieralska, Janusz Limon
Publikováno v:
European journal of medical genetics. 51(2)
We report on a 4-year-old boy with a proximal interstitial deletion in the short arm of chromosome 4p with the karyotype 46,XY,del(4)(p14p15.32),inv(9)(p13q13). For a precise delineation of the deleted region, an array-based comparative genomic hybri
Autor:
Ulla Vanleeuw, Thomas Van Looy, Lise Vreys, Agnieszka Wozniak, Maria Debiec-Rychter, Andre Trouet, Jasmien Wellens, Daphne Hompes, Raf Sciot, Jasmien Cornillie, Haifu Li, Patrick Schöffski, Peter Pokreisz
Publikováno v:
Cancer Research. 75:5353-5353
Background and objective: Dedifferentiated liposarcoma (DDLPS) and synovial sarcoma (SynSa) are aggressive malignant tumors of mesenchymal origin. Prognosis of advanced disease is poor with low response rates to first-line single agent doxorubicin (d
Autor:
Haifu Li, Dana T. Aftab, Maria Debiec-Rychter, Karel Van Den Bossche, Raf Sciot, Patrick Schöffski, Agnieszka Wozniak, Jasmien Wellens, Thomas Van Looy, Daphne Hompes
Publikováno v:
Cancer Research. 75:774-774
Background: Upregulation of receptor tyrosine kinase signaling pathways, including vascular endothelial growth factor receptor (VEGFR) and MET (also known as hepatocyte growth factor receptor), is found in different subtypes of soft tissue sarcoma. C
Autor:
Yemarshet K. Gebreyohannes, Jasmien Wellens, Jasmien Cornillie, Daphne Hompes, Patrick Schöffski, Agnieszka Wozniak, Ulla Vanleeuw, Marguerite Stas, Friedl Sinnaeve, Raf Sciot, Haifu Li, Thomas Van Looy, Maria Debiec-Rychter
Publikováno v:
Cancer Research. 75:1460-1460
Background: STS constitutes a rare and very heterogeneous family of tumors of mesenchymal origin. The limited treatment options available for advanced STS underline the need for reliable preclinical models to test novel therapeutic strategies. Method
Autor:
Jasmien Cornillie, Jasmien Wellens, Patrick Schöffski, Haifu Li, Agnieszka Wozniak, Maria Debiec-Rychter, Ulla Vanleeuw, Lise Vreys, Raf Sciot, Matthew Squires, Yemarshet K. Gebreyohannes, Thomas Van Looy, Ana-Maria Rodringuez
Publikováno v:
Cancer Research. 75:775-775
Background: The majority of GISTs are driven by KIT/PDGFRA gain of function mutations. Advanced GIST is routinely treated with tyrosine kinase inhibitors (TKI; e.g imatinib, sunitinib and regorafenib). However, with time, heterogeneous resistance to
Autor:
Giuseppe Floris, Agnieszka Wozniak, Marguerite Stas, Daphne Hompes, Ulla Vanleeuw, Yemarshet K. Gebreyohannes, Thomas Van Looy, Jasmien Wellens, Jasmien Cornillie, Maria Debiec-Rychter, Haifu Li, Patrick Schöffski, Raf Sciot
Publikováno v:
Cancer Research. 75:1461-1461
Objective: Most GIST are dependent on the KIT/PDGFRA signaling pathway and therefore can be treated with specific tyrosine kinase inhibitors (TKI). With time GIST develop resistance to TKI. We need reliable models which can be used for preclinical dr
Autor:
Patrick Schöffski, Jasmien Cornillie, Peter Pokreisz, Raf Sciot, Agnieszka Wozniak, Daphne Hompes, Jasmien Wellens, Lise Vreys, Maria Debiec-Rychter
Publikováno v:
Journal of Clinical Oncology. 33:e13539-e13539
e13539 Background: DDLPS and SynSa are aggressive mesenchymal tumors with limited sensitivity to the standard-of-care treatment doxorubicin (doxo). We evaluated the efficacy of PhAc-ALGP-doxorubici...
Autor:
Jasmien Cornillie, Haifu Li, Lise Vreys, Yemarshet K. Gebreyohannes, Patrick Schöffski, Maria Debiec-Rychter, Ana-Maria Rodriguez, Thomas Van Looy, Agnieszka Wozniak, Ulla Vanleeuw, Raf Sciot, Jasmien Wellens, Matthew Squires
Publikováno v:
Journal of Clinical Oncology. 33:10532-10532
10532 Background: Advanced GIST is treated with the tyrosine kinase inhibitors imatinib, sunitinib and regorafenib, but the majority of patients develop heterogeneous resistance to these agents. In...
Autor:
Bartosz Wasag, Agnieszka Wozniak, Raf Sciot, Peter Vandenberghe, Louis Guillou, Janusz Limon, Patrick Pauwels, Joris Vermeesch, Michel Stul, Maria Debiec-Rychter
Publikováno v:
Genes, chromosomescancer. 46(3)
Gastrointestinal stromal tumors (GISTs) comprise a biologically diverse group of neoplasms with respect to activating mutations in either KIT or PDGFRA, histology, anatomical site of origin, and clinical aggressiveness. In this study, we applied the
Autor:
Bolesław, Papla, Maria, Harazda, Jarosław, Kuzdzał, Agnieszka, Wozniak, Janusz, Limon, Jerzy, Stachura
Publikováno v:
Polish journal of pathology : official journal of the Polish Society of Pathologists. 56(4)
The authors present a rare case of a synovial sarcoma involving both pleural cavities in a 66-year old woman, confirmed by the t(X;18) translocation detected using the FISH method.