Zobrazeno 31 - 40
of 149
pro vyhledávání: '"Adrienne, Tin"'
Autor:
Anna Köttgen, Dan E. Arking, Zhi Yu, Christie M. Ballantyne, Morgan E. Grams, Adrienne Tin, Jingsha Chen, Linda Zhou, Ron C. Hoogeveen, Jin Jin, Josef Coresh, Nilanjan Chatterjee, Aditya Surapaneni, Bing Yu
Publikováno v:
J Am Soc Nephrol
Background: Genome-wide association studies (GWAS) have revealed numerous loci for kidney function (estimated glomerular filtration rate, eGFR). The relationship of polygenic predictors of eGFR, risk of incident adverse kidney outcomes, and the plasm
Publikováno v:
Nutrients, Vol 12, Iss 10, p 3074 (2020)
Higher serum magnesium is associated with lower risk of multiple morbidities, including diabetes, stroke, and atrial fibrillation, but its potential neuroprotective properties have also been gaining traction in cognitive function and decline research
Externí odkaz:
https://doaj.org/article/cfb4478007a44bf19b649e73724e725c
Autor:
Cristian Pattaro, Alexander Teumer, Mathias Gorski, Audrey Y. Chu, Man Li, Vladan Mijatovic, Maija Garnaas, Adrienne Tin, Rossella Sorice, Yong Li, Daniel Taliun, Matthias Olden, Meredith Foster, Qiong Yang, Ming-Huei Chen, Tune H. Pers, Andrew D. Johnson, Yi-An Ko, Christian Fuchsberger, Bamidele Tayo, Michael Nalls, Mary F. Feitosa, Aaron Isaacs, Abbas Dehghan, Pio d’Adamo, Adebowale Adeyemo, Aida Karina Dieffenbach, Alan B. Zonderman, Ilja M. Nolte, Peter J. van der Most, Alan F. Wright, Alan R. Shuldiner, Alanna C. Morrison, Albert Hofman, Albert V. Smith, Albert W. Dreisbach, Andre Franke, Andre G. Uitterlinden, Andres Metspalu, Anke Tonjes, Antonio Lupo, Antonietta Robino, Åsa Johansson, Ayse Demirkan, Barbara Kollerits, Barry I. Freedman, Belen Ponte, Ben A. Oostra, Bernhard Paulweber, Bernhard K. Krämer, Braxton D. Mitchell, Brendan M. Buckley, Carmen A. Peralta, Caroline Hayward, Catherine Helmer, Charles N. Rotimi, Christian M. Shaffer, Christian Müller, Cinzia Sala, Cornelia M. van Duijn, Aude Saint-Pierre, Daniel Ackermann, Daniel Shriner, Daniela Ruggiero, Daniela Toniolo, Yingchang Lu, Daniele Cusi, Darina Czamara, David Ellinghaus, David S. Siscovick, Douglas Ruderfer, Christian Gieger, Harald Grallert, Elena Rochtchina, Elizabeth J. Atkinson, Elizabeth G. Holliday, Eric Boerwinkle, Erika Salvi, Erwin P. Bottinger, Federico Murgia, Fernando Rivadeneira, Florian Ernst, Florian Kronenberg, Frank B. Hu, Gerjan J. Navis, Gary C. Curhan, George B. Ehret, Georg Homuth, Stefan Coassin, Gian-Andri Thun, Giorgio Pistis, Giovanni Gambaro, Giovanni Malerba, Grant W. Montgomery, Gudny Eiriksdottir, Gunnar Jacobs, Guo Li, H-Erich Wichmann, Harry Campbell, Helena Schmidt, Henri Wallaschofski, Henry Völzke, Hermann Brenner, Heyo K. Kroemer, Holly Kramer, Honghuang Lin, I. Mateo Leach, Ian Ford, Idris Guessous, Igor Rudan, Inga Prokopenko, Ingrid Borecki, Iris M. Heid, Ivana Kolcic, Ivana Persico, J. Wouter Jukema, James F. Wilson, Janine F. Felix, Jasmin Divers, Jean-Charles Lambert, Jeanette M. Stafford, Jean-Michel Gaspoz, Jennifer A. Smith, Jessica D. Faul, Jie Jin Wang, Jingzhong Ding, Joel N. Hirschhorn, John Attia, John B. Whitfield, John Chalmers, Jorma Viikari, Josef Coresh, Joshua C. Denny, Juha Karjalainen, Jyotika K. Fernandes, Karlhans Endlich, Katja Butterbach, Keith L. Keene, Kurt Lohman, Laura Portas, Lenore J. Launer, Leo-Pekka Lyytikäinen, Loic Yengo, Lude Franke, Luigi Ferrucci, Lynda M. Rose, Lyudmyla Kedenko, Madhumathi Rao, Maksim Struchalin, Marcus E. Kleber, Margherita Cavalieri, Margot Haun, Marilyn C. Cornelis, Marina Ciullo, Mario Pirastu, Mariza de Andrade, Mark A. McEvoy, Mark Woodward, Martin Adam, Massimiliano Cocca, Matthias Nauck, Medea Imboden, Melanie Waldenberger, Menno Pruijm, Marie Metzger, Michael Stumvoll, Michele K. Evans, Michele M. Sale, Mika Kähönen, Mladen Boban, Murielle Bochud, Myriam Rheinberger, Niek Verweij, Nabila Bouatia-Naji, Nicholas G. Martin, Nick Hastie, Nicole Probst-Hensch, Nicole Soranzo, Olivier Devuyst, Olli Raitakari, Omri Gottesman, Oscar H. Franco, Ozren Polasek, Paolo Gasparini, Patricia B. Munroe, Paul M. Ridker, Paul Mitchell, Paul Muntner, Christa Meisinger, Johannes H. Smit, ICBP Consortium, AGEN Consortium, CARDIOGRAM, CHARGe-Heart Failure Group, ECHOGen Consortium, Peter Kovacs, Philipp S. Wild, Philippe Froguel, Rainer Rettig, Reedik Mägi, Reiner Biffar, Reinhold Schmidt, Rita P. S. Middelberg, Robert J. Carroll, Brenda W. Penninx, Rodney J. Scott, Ronit Katz, Sanaz Sedaghat, Sarah H. Wild, Sharon L. R. Kardia, Sheila Ulivi, Shih-Jen Hwang, Stefan Enroth, Stefan Kloiber, Stella Trompet, Benedicte Stengel, Stephen J. Hancock, Stephen T. Turner, Sylvia E. Rosas, Sylvia Stracke, Tamara B. Harris, Tanja Zeller, Tatijana Zemunik, Terho Lehtimäki, Thomas Illig, Thor Aspelund, Tiit Nikopensius, Tonu Esko, Toshiko Tanaka, Ulf Gyllensten, Uwe Völker, Valur Emilsson, Veronique Vitart, Ville Aalto, Vilmundur Gudnason, Vincent Chouraki, Wei-Min Chen, Wilmar Igl, Winfried März, Wolfgang Koenig, Wolfgang Lieb, Ruth J. F. Loos, Yongmei Liu, Harold Snieder, Peter P. Pramstaller, Afshin Parsa, Jeffrey R. O’Connell, Katalin Susztak, Pavel Hamet, Johanne Tremblay, Ian H. de Boer, Carsten A. Böger, Wolfram Goessling, Daniel I. Chasman, Anna Köttgen, W. H. Linda Kao, Caroline S. Fox
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-19 (2016)
Reduced glomerular filtration rate (eGFR) is a hallmark of chronic kidney disease. Here, Pattaro et al. conduct a meta-analysis to discover several new loci associated with variation in eGFR and find that genes associated with eGFR loci often encode
Externí odkaz:
https://doaj.org/article/5d9d63e116c24c36a1c1be4822c2160b
Autor:
Anna Köttgen, Adrienne Tin
Publikováno v:
J Am Soc Nephrol
Many Mendelian randomization (MR) studies have recently been published, with inferences on the causal relationships between risk factors and diseases that have potential implications for clinical research. In nephrology, MR methods have been applied
Autor:
B. Gwen Windham, A. Richey Sharrett, Adrienne Tin, Thomas H. Mosley, Chad Blackshear, Kevin J. Sullivan, Keenan A. Walker, Michael Griswold, Rebecca F. Gottesman, Steven G. Younkin, Michelle M. Mielke, David S. Knopman, Jeannette Simino
Publikováno v:
Neurology
Background and ObjectivesTo evaluate the association between midlife plasma amyloid-β (Aβ1-42, Aβ1-40, Aβ42:Aβ40) and risk of mild cognitive impairment (MCI) and dementia.MethodsPlasma Aβ42 and Aβ40 were retrospectively measured with a fluorom
Autor:
Elena V. Feofanova, Pascal Schlosser, Bing Yu, Anna Köttgen, Josef Coresh, Morgan E. Grams, Shengyuan Luo, Adrienne Tin, Dan E. Arking, Sarah Tung, Aditya Surapaneni, Yong Li, Eugene P. Rhee
Publikováno v:
Kidney Int
The genome-wide association study (GWAS) is a powerful means to study genetic determinants of disease traits and generate insights into disease pathophysiology. To date, few GWAS of circulating metabolite levels have been performed in African America
Whole-Exome Sequencing Study Identifies Four Novel Gene Loci Associated with Diabetic Kidney Disease
Autor:
Yang, Pan, Xiao, Sun, Xuenan, Mi, Zhijie, Huang, Yenchih, Hsu, James E, Hixson, Donna, Munzy, Ginger, Metcalf, Nora, Franceschini, Adrienne, Tin, Anna, Köttgen, Michael, Francis, Jennifer A, Brody, Bryan, Kestenbaum, Colleen M, Sitlani, Josyf C, Mychaleckyj, Holly, Kramer, Leslie A, Lange, Xiuqing, Guo, Shih-Jen, Hwang, Marguerite R, Irvin, Jennifer A, Smith, Lisa R, Yanek, Dhananjay, Vaidya, Yii-Der Ida, Chen, Myriam, Fornage, Donald M, Lloyd-Jones, Lifang, Hou, Rasika A, Mathias, Braxton D, Mitchell, Patricia A, Peyser, Sharon L R, Kardia, Donna K, Arnett, Adolfo, Correa, Laura M, Raffield, Ramachandran S, Vasan, L Adrienne, Cupple, Daniel, Levy, Robert C, Kaplan, Kari E, North, Jerome I, Rotter, Charles, Kooperberg, Alexander P, Reiner, Bruce M, Psaty, Russell P, Tracy, Richard A, Gibbs, Alanna C, Morrison, Harold, Feldman, Eric, Boerwinkle, Jiang, He, Tanika N, Kelly
Publikováno v:
Human molecular genetics.
Diabetic kidney disease (DKD) is recognized as an important public health challenge. However, its genomic mechanisms are poorly understood. To identify rare variants for DKD, we conducted a whole-exome sequencing (WES) study leveraging large cohorts
Autor:
Priyanka Nandakumar, Adrienne Tin, Megan L Grove, Jianzhong Ma, Eric Boerwinkle, Josef Coresh, Aravinda Chakravarti
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0176734 (2017)
BackgroundIn older adults (aged 70-74 years), African-Americans have 4-fold higher risk of developing hypertension-attributed end-stage renal disease (ESRD) than European-Americans. A hypothesized mechanism linking hypertension and progressive chroni
Externí odkaz:
https://doaj.org/article/f4636588266f4100a853231ee6304597
Autor:
Adrienne Tin, Kevin J. Sullivan, Keenan A. Walker, Jan Bressler, Rajesh Talluri, Bing Yu, Jeanette Simino, Valborg Gudmundsdottir, Valur Emilsson, Lori L. Jennings, Lenore Launer, Hao Mei, Eric Boerwinkle, B. Gwen Windham, Rebecca Gottesman, Vilmundur Gudnason, Josef Coresh, Myriam Fornage, Thomas H. Mosley
Publikováno v:
Biological Psychiatry Global Open Science.
Autor:
Aditya Surapaneni, Adriana M. Hung, Morgan E. Grams, Anna Köttgen, Josef Coresh, Adrienne Tin, Zihe Zheng, Girish N. Nadkarni, Shengyuan Luo, Pascal Schlosser, Inga Steinbrenner, Bing Yu, Eric Boerwinkle, Dan E. Arking, Eugene P. Rhee
Publikováno v:
Clin J Am Soc Nephrol
BACKGROUND AND OBJECTIVES: Genetic variants in NAT8, a liver- and kidney-specific acetyltransferase encoding gene, have been associated with eGFR and CKD in European populations. Higher circulating levels of two NAT8-associated metabolites, N-δ-acet