Zobrazeno 21 - 30
of 128
pro vyhledávání: '"Adrian Cook"'
Autor:
Adrian Cook, Alex Hoyle, Nicholas D. James, Christopher D. Brawley, Matthew R. Sydes, Noel W. Clarke, Silke Gillessen, J. Calvert, Gerhardt Attard, Adnan Ali, David P. Dearnaley, Malcolm David Mason, Aine M Haran, Hassan Douis, Claire Amos, Mahesh K. B. Parmar, Chris Parker
Publikováno v:
Ali, A, Hoyle, A, Haran, A, Brawley, C D, Cook, A, Amos, C, Calvert, J, Douis, H, Mason, M D, Dearnaley, D P, Attard, G, Gillessen Sommer, S, Parmar, M, Parker, C, Sydes, M R, James, N D & Clarke, N 2021, ' Association of Bone Metastatic Burden With Survival Benefit From Prostate Radiotherapy in Patients With Newly Diagnosed Metastatic Prostate Cancer A Secondary Analysis of a Randomized Clinical Trial ', JAMA oncology . https://doi.org/10.1001/jamaoncol.2020.7857
Importance Prostate radiotherapy (RT) improves survival in men with low-burden metastatic prostate cancer. However, owing to the dichotomized nature of metastatic burden criteria, it is not clear how this benefit varies with bone metastasis counts an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5d29b8ec036335ac4a530ff10ac5d7b
https://research.manchester.ac.uk/en/publications/2900b072-8b82-4343-ac8b-2d78e8b14ad4
https://research.manchester.ac.uk/en/publications/2900b072-8b82-4343-ac8b-2d78e8b14ad4
Autor:
Gerhardt Attard, Laura Murphy, Noel W Clarke, William Cross, Robert J Jones, Christopher C Parker, Silke Gillessen, Adrian Cook, Chris Brawley, Claire L Amos, Nafisah Atako, Cheryl Pugh, Michelle Buckner, Simon Chowdhury, Zafar Malik, J Martin Russell, Clare Gilson, Hannah Rush, Jo Bowen, Anna Lydon, Ian Pedley, Joe M O'Sullivan, Alison Birtle, Joanna Gale, Narayanan Srihari, Carys Thomas, Jacob Tanguay, John Wagstaff, Prantik Das, Emma Gray, Mymoona Alzoueb, Omi Parikh, Angus Robinson, Isabel Syndikus, James Wylie, Anjali Zarkar, George Thalmann, Johann S de Bono, David P Dearnaley, Malcolm D Mason, Duncan Gilbert, Ruth E Langley, Robin Millman, David Matheson, Matthew R Sydes, Louise C Brown, Mahesh K B Parmar, Nicholas D James, Elin Jones, Katherine Hyde, Hilary Glen, Sarah Needleman, Ursula McGovern, Denise Sheehan, Sangeeta Paisey, Richard Shaffer, Mark Beresford, Emilio Porfiri, David Fackrell, Ling Lee, Thiagarajan Sreenivasan, Sue Brock, Simon Brown, Amit Bahl, Mike Smith-Howell, Cathryn Woodward, Mau-Don Phan, Danish Mazhar, Krishna Narahari, Fiona Douglas, Anil Kumar, Abdel Hamid, Azman Ibrahim, Dakshinamoorthy Muthukumar, Matthew Simms, Jane Worlding, Anna Tran, Mohammed Kagzi, Carmel Pezaro, Virgil Sivoglo, Benjamin Masters, Pek Keng-Koh, Caroline Manetta, Duncan McLaren, Nishi Gupta, Stergios Boussios, Henry Taylor, John Graham, Carla Perna, Lucinda Melcher, Warren Grant, Ami Sabharwal, Uschi Hofmann, Robert Dealey, Neil McPhail, Robert Brierly, Lisa Capaldi, Norma Sidek, Peter Whelan, Peter Robson, Alison Falconer, Sarah Rudman, Sindu Vivekanandan, Vinod Mullessey, Maria Vilarino-Varela, Vincent Khoo, Karen Tipples, Mehran Afshar, Patryk Brulinski, Vijay Sangar, Clive Peedell, Ashraf Azzabi, Peter Hoskin, Viwod Mullassery, Santhanam Sundar, Yakhub Khan, Ruth Conroy, Andrew Protheroe, Judith Carser, Paul Rogers, Kathryn Tarver, Stephanie Gibbs, Mohammad Muneeb Khan, Mohan Hingorani, Simon Crabb, Manal Alameddine, Neeraj Bhalla, Robert Hughes, John Logue, Darren Leaning, Salil Vengalil, Daniel Ford, Georgina Walker, Ahmed Shaheen, Omar Khan, Andrew Chan, Imtiaz Ahmed, Serena Hilman, Ian Sayers, Ashok Nikapota, David Bloomfield, Tim Porter, Joji Joseph, Cyrill Rentsch, Ricardo Pereira Mestre, Enrico Roggero, Jörg Beyer, Markus Borner, Raeto Strebel, Dominik Berthold, Daniel Engeler, Hubert John, Razvan Popescu, Donat Durr
Publikováno v:
Attard, Gerhardt; Murphy, Laura; Clarke, Noel W; Cross, William; Jones, Robert J; Parker, Christopher C; Gillessen, Silke; Cook, Adrian; Brawley, Chris; Amos, Claire L; Atako, Nafisah; Pugh, Cheryl; Buckner, Michelle; Chowdhury, Simon; Malik, Zafar; Russell, J Martin; Gilson, Clare; Rush, Hannah; Bowen, Jo; Lydon, Anna; ... (2022). Abiraterone acetate and prednisolone with or without enzalutamide for high-risk non-metastatic prostate cancer: a meta-analysis of primary results from two randomised controlled phase 3 trials of the STAMPEDE platform protocol. The lancet, 399(10323), pp. 447-460. Elsevier 10.1016/S0140-6736(21)02437-5
Systemic Therapy in Advancing or Metastatic Prostate cancer: Evaluation of Drug Efficacy (STAMPEDE) investigators 2022, ' Abiraterone acetate and prednisolone with or without enzalutamide for high-risk non-metastatic prostate cancer: a meta-analysis of primary results from two randomised controlled phase 3 trials of the STAMPEDE platform protocol ', Lancet (London, England), vol. 399, no. 10323, pp. 447-460 . https://doi.org/10.1016/S0140-6736(21)02437-5
Systemic Therapy in Advancing or Metastatic Prostate cancer: Evaluation of Drug Efficacy (STAMPEDE) investigators 2022, ' Abiraterone acetate and prednisolone with or without enzalutamide for high-risk non-metastatic prostate cancer: a meta-analysis of primary results from two randomised controlled phase 3 trials of the STAMPEDE platform protocol ', Lancet (London, England), vol. 399, no. 10323, pp. 447-460 . https://doi.org/10.1016/S0140-6736(21)02437-5
BACKGROUND Men with high-risk non-metastatic prostate cancer are treated with androgen-deprivation therapy (ADT) for 3 years, often combined with radiotherapy. We analysed new data from two randomised controlled phase 3 trials done in a multiarm, mul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d07768ca840f38b8ba6462bcfaa787f1
Publikováno v:
Trials, Vol 21, Iss 1, Pp 1-8 (2020)
Trials
Trials
Background Safety data is required to be collected in all clinical trials and can be separated into two types of data, adverse events and serious adverse events. Often, these types of safety data are collected as two discrete data sets, where adverse
Autor:
Andrew R Clamp, Sharadah Essapen, Adrian Cook, Marcia Hall, Elizabeth C. James, Sarah Williams, Jonathan A. Ledermann, Kate Scatchard, Jae Weon Kim, Jonathan Krell, Abel Zachariah, Gordon C Jayson, Iain A. McNeish, Axel Walther, Anjana Anand, Rachel Jones, Sudha Sundar, Christine Parkinson, Jeff Summers, Robert D. Morgan, Dolores Gallardo-Rincón, Christopher J. Poole, Graham Dark, Rosemary Lord, Rosalind Glasspool, Michelle Lockley
Publikováno v:
The Lancet. Oncology. 22(2)
Summary Background Platinum-based neoadjuvant chemotherapy followed by delayed primary surgery (DPS) is an established strategy for women with newly diagnosed, advanced-stage epithelial ovarian cancer. Although this therapeutic approach has been vali
Autor:
Julien Péron, Michel Tod, Christophe Sajous, Adrian Cook, Gilles Freyer, Timothy J. Perren, Olivier Colomban, Alexandra Leary, Benoit You
Publikováno v:
JNCI Cancer Spectrum
Bevacizumab is approved as a maintenance treatment in first-line setting in advanced-stage III-IV ovarian cancers, because GOG-0218 and ICON-7 phase III trials demonstrated progression-free survival benefits. However, only the subgroup of patients wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23c797afc88f0ce5d9462aa2626a5708
Autor:
Chee Goh, Peter Cooke, Anjali Zarkar, Holly Pickering, Noel W. Clarke, Julian Money-Kyrle, Henriette Lindberg, Wendy R. Parulekar, Klaus Brasso, Mahesh K. B. Parmar, Martin Andreas Røder, Jason F. Lester, S L Morris, Nicholas D. James, Amit Bahl, Rajendra Persad, William Cross, Stephanie Gibbs, Charles Catton, Henrik Jakobsen, Peter Ostler, Rakesh Raman, James M. Wilson, Ian Sayers, Matthew R. Sydes, Ramasamy Jaganathan, Heather Payne, Lisa Owen, Howard Kynaston, Joe M. O'Sullivan, Adrian Cook, Sandeep Gujral, Alvan Pope, Ben Eddy, Chris Parker, Matthew S. Simms, Juliette Anderson, Rick Popert, Prashant Patel, Alastair Henderson, David Bottomley, John P Logue, Peter Meidahl Petersen, Fred Saad, Kathryn Lees, Rohit Chahal, Catherine Heath, S.K. Sundaram
Publikováno v:
Lancet (London, England). 396(10260)
Summary Background The optimal timing of radiotherapy after radical prostatectomy for prostate cancer is uncertain. We aimed to compare the efficacy and safety of adjuvant radiotherapy versus an observation policy with salvage radiotherapy for prosta
Autor:
Kalevi Reijonen, Sheena McCormack, Adrian Cook, Peter Hayes, Béhazine Combadière, Aggeliki Spentzou, Alethea Cope, Annika Vogt, G Haidari, Suzanne Day, Sue Fleck, Drew Hannaman, Robin J. Shattock, Celine Yan, M Wood, H Ridgers
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 10 (2019)
Frontiers in Immunology, Frontiers, 2019, 10, pp.2911. ⟨10.3389/fimmu.2019.02911⟩
Frontiers in Immunology, Vol 10 (2019)
Frontiers in Immunology, Frontiers, 2019, 10, pp.2911. ⟨10.3389/fimmu.2019.02911⟩
International audience; Previous studies have shown targeting different tissues via the transcutaneous (TC) and intramuscular injection (IM) with or without electroporation (EP) has the potential to trigger immune responses to DNA vaccination. The CU
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3da220c39083c221279ecb854d57d94e
Autor:
O. Parikh, Mona Parmar, Silke Gillessen, J. M. Russell, Simon Chowdhury, Laura Murphy, Ian Pedley, Adrian Cook, Noel W. Clarke, Louise Brown, Matthew R. Sydes, William Cross, G. Attard, David Matheson, Anna Lydon, J. Bowen, Zafar Malik, Robert Jones, Chris Parker, Nicholas D. James
Publikováno v:
Annals of Oncology. 32:S1298
This is an accepted manuscript of an abstract published by Elsevier in Annals of Oncology on 01/09/2021, available online: https://doi.org/10.1016/j.annonc.2021.08.2098 The accepted version of the publication may differ from the final published versi
Autor:
Anna V. Tinker, B. You, Nozomu Yanaihara, L-A. Lewsley, Stephen Welch, Tatsuo Kagimura, F. Subtil, Iain A. McNeish, Julien Péron, E. Karamouza, Samantha Hinsley, Xavier Paoletti, R.M. Glasspool, Mansoor Raza Mirza, P. Corbaux, Olivier Colomban, I.L. Ray-Coquard, Kristina Lindemann, Adrian Cook
Publikováno v:
Annals of Oncology. 32:S744