Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Shiyun Chen"'
Publikováno v:
Mol Microbiol
YscX was discovered as an essential part of the Yersinia type III secretion system about 20 years ago. It is required for substrate secretion and is exported itself. Despite this central role, its precise function and mode of action remain unknown. I
Autor:
Matthew S. Francis, Shiyun Chen, Keke Fei, Yangbo Hu, Shaojia Huang, Wei Tang, Xiaoyan Zeng, Huan Yan
Publikováno v:
mBio, Vol 12, Iss 3 (2021)
mBio
mBio
Human-pathogenic Yersinia species employ a plasmid-encoded type III secretion system (T3SS) to negate immune cell function during infection. A critical element in this process is the coordinated regulation of T3SS gene expression, which involves both
Publikováno v:
Microbiology. 167
The CpxRA two-component regulatory system and the Rcs phosphorelay system are both employed by the Enterobacteriaceae family to preserve bacterial envelope integrity and function when growing under stress. Although both systems regulate several overl
Publikováno v:
Microbiology (Reading, England). 167(1)
The CpxRA two-component regulatory system and the Rcs phosphorelay system are both employed by the
Publikováno v:
FEMS microbiology letters. 368(6)
LcrF is the master regulator that positively regulates the Ysc type III secretion system (T3SS) in Yersinia and shares a high similarity with the DNA-binding domain of the T3SS master regulator ExsA in Pseudomonas aeruginosa. Based on these features,
Autor:
Karl M. Thompson, Shiyun Chen, Marcus Fredriksson Sundbom, Ikenna Obi, Monika K. Francis, Matthew S. Francis, Dharmender Kumar Gahlot, Petra Dersch, Kristina Ruuth, Junfa Liu, Jyoti M. Gurung, Edvin J. Thanikkal
Publikováno v:
Virulence
Virulence, Vol 10, Iss 1, Pp 37-57 (2019)
Virulence, Vol 10, Iss 1, Pp 37-57 (2019)
The Gram-negative enteropathogen Yersinia pseudotuberculosis possesses a number of regulatory systems that detect cell envelope damage caused by noxious extracytoplasmic stresses. The CpxA sensor kinase and CpxR response regulator two-component regul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c27fd62cb0eeb8588ac43080dfb3acb8
Autor:
Jyoti M. Gurung, Ayad A. A. Amer, Monika K. Francis, Tiago R. D. Costa, Shiyun Chen, Anton V. Zavialov, Matthew S. Francis
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 8 (2018)
Type III secretion systems harbored by several Gram-negative bacteria are often used to deliver host-modulating effectors into infected eukaryotic cells. About 20 core proteins are needed for assembly of a secretion apparatus. Several of these protei
Publikováno v:
FEMS Microbiology Letters. 317:190-195
Survival in acidic environments is important for successful infection of gastrointestinal pathogens. Many bacteria have evolved elaborate mechanisms by inducing or repressing gene expression, which subsequently provide pH homeostasis and enable acid
Publikováno v:
FEBS Letters. 584:2311-2314
Enteric bacteria have developed various survival systems that protect against acid stress. In this study, an aspartate-dependent acid survival system is characterized in Yersinia pseudotuberculosis. The expression of aspartase (AspA) was confirmed to
Publikováno v:
Microbiology. 155:1890-1900
We describe here the functional characterization of the flgM gene in Yersinia pseudotuberculosis. Direct interaction of FlgM with the alternative sigma factor σ 28 (FliA) was first confirmed. A conserved region in the C-terminus of FlgM was found wh