Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Spector, Td"'
Autor:
Chen J; Exeter Centre of Excellence for Diabetes Research (EXCEED), Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, UK.; Department of Human Genetics, Wellcome Sanger Institute, Cambridge, UK., Spracklen CN; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA.; Department of Biostatistics and Epidemiology, University of Massachusetts, Amherst, MA, USA., Marenne G; Department of Human Genetics, Wellcome Sanger Institute, Cambridge, UK.; Inserm, Univ Brest, EFS, UMR 1078, GGB, Brest, France., Varshney A; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA., Corbin LJ; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.; Department of Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Luan J; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, UK., Willems SM; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, UK., Wu Y; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA., Zhang X; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, UK.; Department of Biostatistics, School of Public Health, Shandong University, Jinan, China., Horikoshi M; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.; Laboratory for Genomics of Diabetes and Metabolism, RIKEN Centre for Integrative Medical Sciences, Yokohama, Japan., Boutin TS; Medical Research Council Human Genetics Unit, Institute for Genetics and Molecular Medicine, Edinburgh, UK., Mägi R; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, Estonia., Waage J; COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark., Li-Gao R; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands., Chan KHK; Department of Epidemiology, Brown University School of Public Health, Brown University, Providence, RI, USA.; Department of Biomedical Sciences, City University of Hong Kong, Hong Kong SAR, China.; Department of Electrical Engineering, City University of Hong Kong, Hong Kong SAR, China., Yao J; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Anasanti MD; Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK., Chu AY; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA., Claringbould A; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Heikkinen J; Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK., Hong J; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Hottenga JJ; Department of Biological Psychology, Faculty of Behaviour and Movement Sciences, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.; Amsterdam Public Health Research Institute, Amsterdam University Medical Center, Amsterdam, the Netherlands., Huo S; CAS Key Laboratory of Nutrition, Metabolism and Food Safety, Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China., Kaakinen MA; Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK.; Section of Statistical Multi-omics, Department of Clinical and Experimental Research, University of Surrey, Guildford, UK., Louie T; Department of Biostatistics, University of Washington, Seattle, WA, USA., März W; SYNLAB Academy, SYNLAB Holding Deutschland GmbH, Mannheim, Germany.; Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University Graz, Graz, Austria.; Vth Department of Medicine (Nephrology, Hypertensiology, Rheumatology, Endocrinology, Diabetology), Medical Faculty Mannheim, Heidelberg University, Mannheim, Baden-Württemberg, Germany., Moreno-Macias H; Department of Economics, Metropolitan Autonomous University, Mexico City, Mexico., Ndungu A; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK., Nelson SC; Department of Biostatistics, University of Washington, Seattle, WA, USA., Nolte IM; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., North KE; CVD Genetic Epidemiology Computational Laboratory, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA., Raulerson CK; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA., Ray D; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA., Rohde R; CVD Genetic Epidemiology Computational Laboratory, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA., Rybin D; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Schurmann C; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; HPI Digital Health Center, Digital Health and Personalized Medicine, Hasso Plattner Institute, Potsdam, Germany., Sim X; Saw Swee Hock School of Public Health, National Univeristy of Singapore and National University Health System, Singapore, Singapore.; Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA.; Department of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, MI, USA., Southam L; Department of Human Genetics, Wellcome Sanger Institute, Cambridge, UK.; Institute of Translational Genomics, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany., Stewart ID; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, UK., Wang CA; School of Medicine and Public Health, College of Health, Medicine and Wellbeing, The University of Newcastle, Newcastle, New South Wales, Australia., Wang Y; CVD Genetic Epidemiology Computational Laboratory, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA., Wu P; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Zhang W; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; Department of Cardiology, Ealing Hospital, London North West Healthcare NHS Trust, London, UK., Ahluwalia TS; COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.; Steno Diabetes Center Copenhagen, Gentofte, Denmark.; The Bioinformatics Centre, Department of Biology, University of Copenhagen, Copenhagen, Denmark., Appel EVR; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Bielak LF; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA., Brody JA; Department of Medicine, Cardiovascular Health Research Unit, University of Washington, Seattle, WA, USA., Burtt NP; Metabolism Program, Program in Medical and Population Genetics, Broad Institute, Cambridge, MA, USA., Cabrera CP; Department of Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; NIHR Barts Cardiovascular Biomedical Research Centre, Queen Mary University of London, London, UK., Cade BE; Department of Medicine, Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, MA, USA.; Department of Medicine, Sleep Medicine, Harvard Medical School, Boston, MA, USA., Chai JF; Saw Swee Hock School of Public Health, National Univeristy of Singapore and National University Health System, Singapore, Singapore., Chai X; Ocular Epidemiology, Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore.; Department of Ophthalmology, National University of Singapore and National University Health System, Singapore, Singapore., Chang LC; Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan., Chen CH; Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan., Chen BH; Department of Epidemiology, The Herbert Wertheim School of Public Health and Human Longevity Science, University of California San Diego, La Jolla, CA, USA., Chitrala KN; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA., Chiu YF; Institute of Population Health Sciences, National Health Research Institutes, Miaoli, Taiwan., de Haan HG; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands., Delgado GE; Vth Department of Medicine (Nephrology, Hypertensiology, Rheumatology, Endocrinology, Diabetology), Medical Faculty Mannheim, Heidelberg University, Mannheim, Baden-Württemberg, Germany., Demirkan A; Section of Statistical Multi-omics, Department of Clinical and Experimental Research, University of Surrey, Guildford, UK.; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands., Duan Q; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA.; Department of Statistics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Engmann J; Institute of Cardiovascular Science, University College London, London, UK., Fatumo SA; Uganda Medical Informatics Centre (UMIC), MRC/UVRI and London School of Hygiene & Tropical Medicine (Uganda Research Unit), Entebbe, Uganda.; London School of Hygiene & Tropical Medicine, London, UK.; H3Africa Bioinformatics Network (H3ABioNet) Node, Centre for Genomics Research and Innovation, NABDA/FMST, Abuja, Nigeria., Gayán J; Bioinfosol, Sevilla, Spain., Giulianini F; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA., Gong JH; Department of Epidemiology, Brown University School of Public Health, Brown University, Providence, RI, USA., Gustafsson S; Molecular Epidemiology and Science for Life Laboratory, Department of Medical Sciences, Uppsala University, Uppsala, Sweden., Hai Y; Department of Statistics, The University of Auckland, Science Center, Auckland, New Zealand., Hartwig FP; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.; Postgraduate Program in Epidemiology, Federal University of Pelotas, Pelotas, Brazil., He J; Department of Medicine, Epidemiology, Vanderbilt University Medical Center, Nashville, TN, USA., Heianza Y; Department of Epidemiology, Tulane University Obesity Research Center, Tulane University, New Orleans, LA, USA., Huang T; Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing, China., Huerta-Chagoya A; Molecular Biology and Genomic Medicine Unit, National Council for Science and Technology, Mexico City, Mexico.; Molecular Biology and Genomic Medicine Unit, National Institute of Medical Sciences and Nutrition, Mexico City, Mexico., Hwang MY; Division of Genome Science, Department of Precision Medicine, National Institute of Health, Cheongju, South Korea., Jensen RA; Department of Medicine, Cardiovascular Health Research Unit, University of Washington, Seattle, WA, USA., Kawaguchi T; Center for Genomic Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan., Kentistou KA; Centre for Global Health Research, Usher Institute, University of Edinburgh, Edinburgh, UK.; Centre for Cardiovascular Sciences, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, UK., Kim YJ; Division of Genome Science, Department of Precision Medicine, National Institute of Health, Cheongju, South Korea., Kleber ME; Vth Department of Medicine (Nephrology, Hypertensiology, Rheumatology, Endocrinology, Diabetology), Medical Faculty Mannheim, Heidelberg University, Mannheim, Baden-Württemberg, Germany., Kooner IK; Department of Cardiology, Ealing Hospital, London North West Healthcare NHS Trust, London, UK., Lai S; Department of Epidemiology, Brown University School of Public Health, Brown University, Providence, RI, USA., Lange LA; Department of Medicine, Divison of Biomedical Informatics and Personalized Medicine, University of Colorado Anschutz Medical Campus, Denver, CO, USA., Langefeld CD; Department of Biostatistics and Data Science, Wake Forest School of Medicine, Winston-Salem, NC, USA., Lauzon M; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Li M; Department of Medicine, Division of Nephrology and Hypertension, University of Utah, Salt Lake City, UT, USA., Ligthart S; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands., Liu J; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.; Nuffield Department of Population Health, University of Oxford, Oxford, UK., Loh M; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore., Long J; Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University Medical Center, Nashville, TN, USA., Lyssenko V; Department of Clinical Science, Center for Diabetes Research, University of Bergen, Bergen, Norway.; Department of Clinical Sciences, Lund University Diabetes Centre, Lund University, Malmo, Sweden., Mangino M; Department of Twin Research and Genetic Epidemiology, School of Life Course Sciences, King's College London, London, UK.; NIHR Biomedical Research Centre, Guy's and St Thomas' NHS Foundation Trust, London, UK., Marzi C; Institute of Epidemiology, Research Unit of Molecular Epidemiology, Helmholtz Zentrum München Research Center for Environmental Health, Neuherberg, Germany.; German Center for Diabetes Research (DZD), Neuherberg, Germany., Montasser ME; Department of Medicine, Division of Endocrinology, Diabetes and Nutrition, University of Maryland School of Medicine, Baltimore, MD, USA., Nag A; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK., Nakatochi M; Public Health Informatics Unit, Department of Integrated Sciences, Nagoya University Graduate School of Medicine, Nagoya, Japan., Noce D; Institute for Biomedicine, Eurac Research, Bolzano, Italy., Noordam R; Department of Internal Medicine, Section of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, the Netherlands., Pistis G; Istituto di Ricerca Genetica e Biomedica (IRGB), Consiglio Nazionale delle Ricerche (CNR), Monserrato, Italy., Preuss M; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; The Mindich Child Health and Development Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Raffield L; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA., Rasmussen-Torvik LJ; Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Rich SS; Center for Public Health Genomics, University of Virginia, Charlottesville, VA, USA.; Department of Public Health Sciences, University of Virginia, Charlottesville, VA, USA., Robertson NR; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK., Rueedi R; Department of Computational Biology, University of Lausanne, Lausanne, Switzerland.; Swiss Institute of Bioinformatics, Lausanne, Switzerland., Ryan K; Department of Medicine, Division of Endocrinology, Diabetes and Nutrition, University of Maryland School of Medicine, Baltimore, MD, USA., Sanna S; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.; Istituto di Ricerca Genetica e Biomedica (IRGB), Consiglio Nazionale delle Ricerche (CNR), Monserrato, Italy., Saxena R; Center for Genomic Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.; Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Boston, MA, USA.; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA, USA., Schraut KE; Centre for Global Health Research, Usher Institute, University of Edinburgh, Edinburgh, UK.; Centre for Cardiovascular Sciences, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, UK., Sennblad B; Department of Cell and Molecular Biology, National Bioinformatics Infrastructure Sweden, Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Setoh K; Center for Genomic Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan., Smith AV; Department of Biostatistics, University of Michigan, Ann Arbor, MI, USA.; Icelandic Heart Association, Kopavogur, Iceland., Sparsø T; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Strawbridge RJ; Institute of Health and Wellbeing, University of Glasgow, Glasgow, UK.; Department of Medicine Solna, Cardiovascular Medicine, Karolinska Institutet, Stockholm, Sweden., Takeuchi F; National Center for Global Health and Medicine, Tokyo, Japan., Tan J; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Trompet S; Department of Internal Medicine, Section of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, the Netherlands.; Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands., van den Akker E; Department of Biomedical Data Sciences, Molecular Epidemiology, Leiden University Medical Center, Leiden, the Netherlands.; Department of Pattern Recognition and Bioinformatics, Delft University of Technology, Delft, the Netherlands.; Department of Biomedical Data Sciences, Leiden Computational Biology Center, Leiden University Medical Center, Leiden, the Netherlands., van der Most PJ; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Verweij N; Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.; Genomics PLC, Oxford, UK., Vogel M; Center of Pediatric Research, University Children's Hospital Leipzig, University of Leipzig Medical Center, Leipzig, Germany., Wang H; Department of Medicine, Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, MA, USA.; Department of Medicine, Sleep Medicine, Harvard Medical School, Boston, MA, USA., Wang C; Department of Epidemiology and Biostatistics, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.; Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore, Singapore., Wang N; Department of Preventive Medicine, Keck School of Medicine of University of Southern California, Los Angeles, CA, USA.; University of Southern California Diabetes and Obesity Research Institute, Keck School of Medicine of University of Southern California, Los Angeles, CA, USA., Warren HR; Department of Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; NIHR Barts Cardiovascular Biomedical Research Centre, Queen Mary University of London, London, UK., Wen W; Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University Medical Center, Nashville, TN, USA., Wilsgaard T; Department of Community Medicine, Faculty of Health Sciences, UIT the Arctic University of Norway, Tromsø, Norway., Wong A; MRC Unit for Lifelong Health and Ageing at University College London, London, UK., Wood AR; Exeter Centre of Excellence for Diabetes Research (EXCEED), Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, UK., Xie T; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Zafarmand MH; Department of Public Health, Amsterdam Public Health Research Institute, Amsterdam University Medical Center, Amsterdam, the Netherlands.; Department of Clinical Epidemiology, Biostatistics, and Bioinformatics, Amsterdam Public Health Research Institute, Amsterdam University Medical Center, Amsterdam, the Netherlands., Zhao JH; Department of Public Health and Primary Care, School of Clinical Medicine, University of Cambridge, Cambridge, UK., Zhao W; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA., Amin N; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.; Nuffield Department of Population Health, University of Oxford, Oxford, UK., Arzumanyan Z; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Astrup A; Department of Nutrition, Exercise, and Sports, Faculty of Science, University of Copenhagen, Copenhagen, Denmark., Bakker SJL; Department of Internal Medicine, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Baldassarre D; Department of Medical Biotechnology and Translational Medicine, University of Milan, Milan, Italy.; Centro Cardiologico Monzino, IRCCS, Milan, Italy., Beekman M; Department of Biomedical Data Sciences, Molecular Epidemiology, Leiden University Medical Center, Leiden, the Netherlands., Bergman RN; Diabetes and Obesity Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Bertoni A; Department of Epidemiology and Prevention, Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, NC, USA., Blüher M; Medical Department III-Endocrinology, Nephrology, Rheumatology, University of Leipzig Medical Center, Leipzig, Germany., Bonnycastle LL; Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, National Institues of Health, Bethesda, MD, USA., Bornstein SR; Department for Prevention and Care of Diabetes, Faculty of Medicine Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany., Bowden DW; Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC, USA., Cai Q; Department of Medicine, Epidemiology, Vanderbilt University Medical Center, Nashville, TN, USA., Campbell A; Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, UK.; Usher Institute, University of Edinburgh, Edinburgh, UK., Campbell H; Centre for Global Health Research, Usher Institute, University of Edinburgh, Edinburgh, UK., Chang YC; Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.; Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.; Graduate Institute of Medical Genomics and Proteomics, National Taiwan University, Taipei, Taiwan., de Geus EJC; Department of Biological Psychology, Faculty of Behaviour and Movement Sciences, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.; Amsterdam Public Health Research Institute, Amsterdam University Medical Center, Amsterdam, the Netherlands., Dehghan A; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands., Du S; Department of Nutrition, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA., Eiriksdottir G; Icelandic Heart Association, Kopavogur, Iceland., Farmaki AE; Department of Population Science and Experimental Medicine, Institute of Cardiovascular Science, University College London, London, UK.; Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University of Athens, Athens, Greece., Frånberg M; Department of Medicine Solna, Cardiovascular Medicine, Karolinska Institutet, Stockholm, Sweden., Fuchsberger C; Institute for Biomedicine, Eurac Research, Bolzano, Italy., Gao Y; Department of Epidemiology, Shanghai Cancer Institute, Shanghai, China., Gjesing AP; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Goel A; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Han S; Division of Genome Science, Department of Precision Medicine, National Institute of Health, Cheongju, South Korea., Hartman CA; Department of Psychiatry, Interdisciplinary Center Psychopathy and Emotion Regulation, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Herder C; Institute for Clinical Diabetology, German Diabetes Center, Leibniz Center for Diabetes Research at Heinrich Heine University Düsseldorf, Düsseldorf, Germany.; Division of Endocrinology and Diabetology, Medical Faculty, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.; German Center for Diabetes Research (DZD), Düsseldorf, Germany., Hicks AA; Institute for Biomedicine, Eurac Research, Bolzano, Italy., Hsieh CH; Internal Medicine, Endocrine and Metabolism, Tri-Service General Hospital, Taipei, Taiwan.; School of Medicine, National Defense Medical Center, Taipei, Taiwan., Hsueh WA; Internal Medicine, Endocrinology, Diabetes and Metabolism, Diabetes and Metabolism Research Center, The Ohio State University Wexner Medical Center, Columbus, OH, USA., Ichihara S; Department of Environmental and Preventive Medicine, Jichi Medical University School of Medicine, Shimotsuke, Japan., Igase M; Department of Anti-aging Medicine, Ehime University Graduate School of Medicine, Toon, Japan., Ikram MA; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands., Johnson WC; Department of Biostatistics, University of Washington, Seattle, WA, USA., Jørgensen ME; Steno Diabetes Center Copenhagen, Gentofte, Denmark.; National Institute of Public Health, University of Southern Denmark, Odense, Denmark., Joshi PK; Centre for Global Health Research, Usher Institute, University of Edinburgh, Edinburgh, UK., Kalyani RR; Department of Medicine, Endocrinology, Diabetes and Metabolism, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Kandeel FR; Clinical Diabetes, Endocrinology and Metabolism, Translational Research and Cellular Therapeutics, Beckman Research Institute of the City of Hope, Duarte, CA, USA., Katsuya T; Department of Clinical Gene Therapy, Osaka University Graduate School of Medicine, Suita, Japan.; Department of Geriatric and General Medicine, Osaka University Graduate School of Medicine, Suita, Japan., Khor CC; Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore, Singapore., Kiess W; Center of Pediatric Research, University Children's Hospital Leipzig, University of Leipzig Medical Center, Leipzig, Germany., Kolcic I; Department of Public Health, University of Split School of Medicine, Split, Croatia., Kuulasmaa T; Institute of Biomedicine, Bioinformatics Center, Univeristy of Eastern Finland, Kuopio, Finland., Kuusisto J; Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland., Läll K; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, Estonia., Lam K; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Lawlor DA; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.; Department of Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Lee NR; USC-Office of Population Studies Foundation, University of San Carlos, Cebu City, the Philippines.; Department of Anthropology, Sociology and History, University of San Carlos, Cebu City, the Philippines., Lemaitre RN; Department of Medicine, Cardiovascular Health Research Unit, University of Washington, Seattle, WA, USA., Li H; State Key Laboratory of Oncogene and Related Genes and Department of Epidemiology, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China., Lin SY; Center for Geriatrics and Gerontology, Taichung Veterans General Hospital, Taichung, Taiwan.; National Defense Medical Center, National Yang-Ming University, Taipei, Taiwan., Lindström J; Diabetes Prevention Unit, National Institute for Health and Welfare, Helsinki, Finland., Linneberg A; Center for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Liu J; Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore, Singapore.; Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore, Singapore., Lorenzo C; Department of Medicine, University of Texas Health Sciences Center, San Antonio, TX, USA., Matsubara T; Department of Internal Medicine, Aichi Gakuin University School of Dentistry, Nagoya, Japan., Matsuda F; Center for Genomic Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan., Mingrone G; Department of Diabetes, Diabetes, and Nutritional Sciences, James Black Centre, King's College London, London, UK., Mooijaart S; Department of Internal Medicine, Section of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, the Netherlands., Moon S; Division of Genome Science, Department of Precision Medicine, National Institute of Health, Cheongju, South Korea., Nabika T; Department of Functional Pathology, Shimane University School of Medicine, Izumo, Japan., Nadkarni GN; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Nadler JL; Department of Medicine and Pharmacology, New York Medical College School of Medicine, Valhalla, NY, USA., Nelis M; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, Estonia., Neville MJ; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; Oxford NIHR Biomedical Research Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, UK., Norris JM; Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, CO, USA., Ohyagi Y; Department of Geriatric Medicine and Neurology, Ehime University Graduate School of Medicine, Toon, Japan., Peters A; German Center for Diabetes Research (DZD), Neuherberg, Germany.; Institute of Epidemiology, Helmholtz Zentrum München Research Center for Environmental Health, Neuherberg, Germany.; Institute for Medical Information Processing, Biometry and Epidemiology, Ludwig-Maximilians University Munich, Munich, Germany., Peyser PA; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA., Polasek O; Department of Public Health, University of Split School of Medicine, Split, Croatia.; Gen-Info, Zagreb, Croatia., Qi Q; Department of Epidemiology and Population Health, Albert Einstein College of Medicine, New York, NY, USA., Raven D; Department of Psychiatry, Interdisciplinary Center Psychopathy and Emotion Regulation, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Reilly DF; Genetics and Pharmacogenomics, Merck Sharp & Dohme, Kenilworth, NJ, USA., Reiner A; Department of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA., Rivideneira F; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, the Netherlands., Roll K; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Rudan I; Centre for Global Health, The Usher Institute, University of Edinburgh, Edinburgh, UK., Sabanayagam C; Ocular Epidemiology, Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore.; Ophthalmology & Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore, Singapore., Sandow K; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Sattar N; BHF Glasgow Cardiovascular Research Centre, Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK., Schürmann A; German Center for Diabetes Research (DZD), Neuherberg, Germany.; Department of Experimental Diabetology, German Institute of Human Nutrition Potsdam-Rehbruecke, Nuthetal, Germany., Shi J; Department of Genetics, Shanghai-MOST Key Laboratory of Health and Disease Genomics, Chinese National Human Genome Center at Shanghai (CHGC) and Shanghai Academy of Science & Technology (SAST), Shanghai, China., Stringham HM; Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA.; Department of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, MI, USA., Taylor KD; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Teslovich TM; Sarepta Therapeutics, Cambridge, MA, USA., Thuesen B; Center for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark., Timmers PRHJ; Centre for Global Health Research, Usher Institute, University of Edinburgh, Edinburgh, UK.; Medical Research Council Human Genetics Unit, Institute for Genetics and Cancer, University of Edinburgh, Edinburgh, UK., Tremoli E; Centro Cardiologico Monzino, IRCCS, Milan, Italy., Tsai MY; Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN, USA., Uitterlinden A; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, the Netherlands., van Dam RM; Saw Swee Hock School of Public Health, National Univeristy of Singapore and National University Health System, Singapore, Singapore.; Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore, Singapore.; Department of Nutrition, Harvard T. H. 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Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, the Netherlands.; Department of Human Genetics, Leiden University Medical Center, Leiden, the Netherlands., Zemunik T; Department of Human Biology, University of Split School of Medicine, Split, Croatia., Abecasis GR; Department of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, MI, USA., Adair LS; Department of Nutrition, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA.; Carolina Population Center, University of North Carolina, Chapel Hill, NC, USA., Aguilar-Salinas CA; Department of Endocrinology and Metabolism, Instituto Nacional de Ciencias Medicas y Nutricion, Mexico City, Mexico.; Unidad de Investigación de Enfermedades Metabólicas, Instituto Nacional de Ciencias Médicas y Nutrición and Tec Salud, Mexico City, Mexico.; Instituto Tecnológico y de Estudios Superiores de Monterrey Tec Salud, Monterrey, Mexico., Alarcón-Riquelme ME; Department of Medical Genomics, Pfizer/University of Granada/Andalusian Government Center for Genomics and Oncological Research (GENYO), Granada, Spain.; Institute for Environmental Medicine, Chronic Inflammatory Diseases, Karolinska Institutet, Solna, Sweden., An P; Department of Genetics, Division of Statistical Genomics, Washington University School of Medicine, St Louis, MO, USA., Aviles-Santa L; Clinical and Health Services Research, National Institute on Minority Health and Health Disparities, Bethesda, MD, USA., Becker DM; Department of Medicine, General Internal Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Beilin LJ; Medical School, Royal Perth Hospital Unit, University of Western Australia, Perth, Western Australia, Australia., Bergmann S; Department of Computational Biology, University of Lausanne, Lausanne, Switzerland.; Swiss Institute of Bioinformatics, Lausanne, Switzerland.; Department of Integrative Biomedical Sciences, University of Cape Town, Cape Town, South Africa., Bisgaard H; COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark., Black C; Aberdeen Centre for Health Data Science, School of Medicine, Medical Sciences and Nutrition, University of Aberdeen, Aberdeen, UK., Boehnke M; Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA.; Department of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, MI, USA., Boerwinkle E; Human Genetics Center, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA.; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA., Böhm BO; Division of Endocrinology and Diabetes, Graduate School of Molecular Endocrinology and Diabetes, University of Ulm, Ulm, Germany.; LKC School of Medicine, Nanyang Technological University, Singapore and Imperial College London, UK, Singapore, Singapore., Bønnelykke K; COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark., Boomsma DI; Department of Biological Psychology, Faculty of Behaviour and Movement Sciences, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.; Amsterdam Public Health Research Institute, Amsterdam University Medical Center, Amsterdam, the Netherlands., Bottinger EP; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Hasso Plattner Institute for Digital Health at Mount Sinai, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Digital Health Center, Hasso Plattner Institut, University Potsdam, Potsdam, Germany., Buchanan TA; University of Southern California Diabetes and Obesity Research Institute, Keck School of Medicine of University of Southern California, Los Angeles, CA, USA.; Department of Medicine, Keck School of Medicine of University of Southern California, Los Angeles, CA, USA.; Department of Physiology and Neuroscience, Keck School of Medicine of University of Southern California, Los Angeles, CA, USA., Canouil M; INSERM UMR 1283/CNRS UMR 8199, European Institute for Diabetes (EGID), Université de Lille, Lille, France.; INSERM UMR 1283/CNRS UMR 8199, European Institute for Diabetes (EGID), Institut Pasteur de Lille, Lille, France., Caulfield MJ; Department of Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; NIHR Barts Cardiovascular Biomedical Research Centre, Queen Mary University of London, London, UK., Chambers JC; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; Department of Cardiology, Ealing Hospital, London North West Healthcare NHS Trust, London, UK.; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.; Imperial College Healthcare NHS Trust, Imperial College London, London, UK.; MRC-PHE Centre for Environment and Health, Imperial College London, London, UK., Chasman DI; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Chen YI; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Cheng CY; Ocular Epidemiology, Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore.; Ophthalmology & Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore, Singapore., Collins FS; Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, National Institues of Health, Bethesda, MD, USA., Correa A; Department of Medicine, Jackson Heart Study, University of Mississippi Medical Center, Jackson, MS, USA., Cucca F; Istituto di Ricerca Genetica e Biomedica (IRGB), Consiglio Nazionale delle Ricerche (CNR), Monserrato, Italy., de Silva HJ; Department of Medicine, Faculty of Medicine, University of Kelaniya, Ragama, Sri Lanka., Dedoussis G; Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University of Athens, Kallithea, Greece., Elmståhl S; Department of Clinical Sciences, Lund University, Malmö, Sweden., Evans MK; Laboratory of Epidemiology and Population Sciences, National Institute on Aging Intramural Research Program, National Institutes of Health, Baltimore, MD, USA., Ferrannini E; CNR Institute of Clinical Physiology, Pisa, Italy., Ferrucci L; Intramural Research Program, National Institute of Aging, Baltimore, MD, USA., Florez JC; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA, USA.; Diabetes Unit and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Franks PW; Department of Clinical Sciences, Lund University Diabetes Centre, Lund University, Malmo, Sweden.; Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden., Frayling TM; Exeter Centre of Excellence for Diabetes Research (EXCEED), Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, UK., Froguel P; INSERM UMR 1283/CNRS UMR 8199, European Institute for Diabetes (EGID), Université de Lille, Lille, France.; INSERM UMR 1283/CNRS UMR 8199, European Institute for Diabetes (EGID), Institut Pasteur de Lille, Lille, France.; Department of Genomics of Common Disease, Imperial College London, London, UK., Gigante B; Department of Medicine, Cardiovascular Medicine, Karolinska Institutet, Stockholm, Sweden., Goodarzi MO; Department of Medicine, Division of Endocrinology, Diabetes and Metabolism, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Gordon-Larsen P; Department of Nutrition, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA.; Carolina Population Center, University of North Carolina, Chapel Hill, NC, USA., Grallert H; Institute of Epidemiology, Research Unit of Molecular Epidemiology, Helmholtz Zentrum München Research Center for Environmental Health, Neuherberg, Germany.; German Center for Diabetes Research (DZD), Neuherberg, Germany., Grarup N; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Grimsgaard S; Department of Community Medicine, Faculty of Health Sciences, UIT the Arctic University of Norway, Tromsø, Norway., Groop L; Diabetes Centre, Lund University, Lund, Sweden.; Finnish Institute of Molecular Medicine, Helsinki University, Helsinki, Finland., Gudnason V; Icelandic Heart Association, Kopavogur, Iceland.; Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland., Guo X; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Hamsten A; Department of Medicine Solna, Cardiovascular Medicine, Karolinska Institutet, Stockholm, Sweden., Hansen T; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Hayward C; Medical Research Council Human Genetics Unit, Institute for Genetics and Cancer, University of Edinburgh, Edinburgh, UK., Heckbert SR; Department of Epidemiology, Cardiovascular Health Research Unit, University of Washington, Seattle, WA, USA., Horta BL; Postgraduate Program in Epidemiology, Federal University of Pelotas, Pelotas, Brazil., Huang W; Department of Genetics, Shanghai-MOST Key Laboratory of Health and Disease Genomics, Chinese National Human Genome Center at Shanghai (CHGC) and Shanghai Academy of Science & Technology (SAST), Shanghai, China., Ingelsson E; Department of Medicine, Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford University, Stanford, CA, USA., James PS; Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, MN, USA., Jarvelin MR; Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.; Center for Life Course Health Research, Faculty of Medicine, University of Oulu, Oulu, Finland.; Unit of Primary Health Care, Oulu Univerisity Hospital, OYS, Oulu, Finland.; Department of Life Sciences, College of Health and Life Sciences, Brunel University London, London, UK., Jonas JB; Department of Ophthalmology, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.; Beijing Institute of Ophthalmology, Beijing Ophthalmology and Visual Science Key Lab, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing, China.; Institute of Molecular and Clinical Ophthalmology Basel IOB, Basel, Switzerland., Jukema JW; Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands.; Netherlands Heart Institute, Utrecht, the Netherlands., Kaleebu P; MRC/UVRI and LSHTM (Uganda Research Unit), Entebbe, Uganda., Kaplan R; Department of Epidemiology and Population Health, Albert Einstein College of Medicine, New York, NY, USA.; Department of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA., Kardia SLR; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA., Kato N; National Center for Global Health and Medicine, Tokyo, Japan., Keinanen-Kiukaanniemi SM; Faculty of Medicine, Institute of Health Sciences, University of Oulu, Oulu, Finland.; Unit of General Practice, Oulu University Hospital, Oulu, Finland., Kim BJ; Division of Genome Science, Department of Precision Medicine, National Institute of Health, Cheongju, South Korea., Kivimaki M; Department of Epidemiology and Public Health, University College London, London, UK., Koistinen HA; Department of Public Health Solutions, Finnish Institute for Health and Welfare, Helsinki, Finland.; Department of Medicine, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland.; Minerva Foundation Institute for Medical Research, Helsinki, Finland., Kooner JS; Department of Cardiology, Ealing Hospital, London North West Healthcare NHS Trust, London, UK.; Imperial College Healthcare NHS Trust, Imperial College London, London, UK.; MRC-PHE Centre for Environment and Health, Imperial College London, London, UK.; National Heart and Lung Institute, Imperial College London, London, UK., Körner A; Center of Pediatric Research, University Children's Hospital Leipzig, University of Leipzig Medical Center, Leipzig, Germany., Kovacs P; Medical Department III-Endocrinology, Nephrology, Rheumatology, University of Leipzig Medical Center, Leipzig, Germany.; IFB Adiposity Diseases, University of Leipzig Medical Center, Leipzig, Germany., Kuh D; MRC Unit for Lifelong Health and Ageing at University College London, London, UK., Kumari M; Institute for Social and Economic Research, University of Essex, Colchester, UK., Kutalik Z; Swiss Institute of Bioinformatics, Lausanne, Switzerland.; University Institute of Primary Care and Public Health, Division of Biostatistics, University of Lausanne, Lausanne, Switzerland., Laakso M; Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland., Lakka TA; Institute of Biomedicine, School of Medicine, University of Eastern Finland, Kuopio, Finland.; Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, Finland.; Foundation for Research in Health Exercise and Nutrition, Kuopio Research Institute of Exercise Medicine, Kuopio, Finland., Launer LJ; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA., Leander K; Institute of Environmental Medicine, Cardiovascular and Nutritional Epidemiology, Karolinska Institutet, Stockholm, Sweden., Li H; CAS Key Laboratory of Nutrition, Metabolism and Food Safety, Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China., Lin X; CAS Key Laboratory of Nutrition, Metabolism and Food Safety, Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China., Lind L; Department of Medical Sciences, University of Uppsala, Uppsala, Sweden., Lindgren C; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.; Big Data Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Nuffield Department of Women's and Reproductive Health, University of Oxford, Oxford, UK., Liu S; Department of Epidemiology, Brown University School of Public Health, Brown University, Providence, RI, USA., Loos RJF; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; The Mindich Child Health and Development Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Magnusson PKE; Department of Medical Epidemiology and Biostatistics and the Swedish Twin Registry, Karolinska Institutet, Stockholm, Sweden., Mahajan A; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.; Genentech, South San Francisco, CA, USA., Metspalu A; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, Estonia., Mook-Kanamori DO; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands.; Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, the Netherlands., Mori TA; Medical School, Royal Perth Hospital Unit, University of Western Australia, Perth, Western Australia, Australia., Munroe PB; Department of Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; NIHR Barts Cardiovascular Biomedical Research Centre, Queen Mary University of London, London, UK., Njølstad I; Department of Community Medicine, Faculty of Health Sciences, UIT the Arctic University of Norway, Tromsø, Norway., O'Connell JR; Department of Medicine, Division of Endocrinology, Diabetes and Nutrition, University of Maryland School of Medicine, Baltimore, MD, USA., Oldehinkel AJ; Department of Psychiatry, Interdisciplinary Center Psychopathy and Emotion Regulation, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Ong KK; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, UK., Padmanabhan S; Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK., Palmer CNA; Division of Population Health and Genomics, School of Medicine, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK., Palmer ND; Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC, USA., Pedersen O; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Pennell CE; School of Medicine and Public Health, College of Health, Medicine and Wellbeing, The University of Newcastle, Newcastle, New South Wales, Australia., Porteous DJ; Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, UK.; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK., Pramstaller PP; Institute for Biomedicine, Eurac Research, Bolzano, Italy., Province MA; Department of Genetics, Division of Statistical Genomics, Washington University School of Medicine, St Louis, MO, USA., Psaty BM; Department of Medicine, Cardiovascular Health Research Unit, University of Washington, Seattle, WA, USA.; Department of Epidemiology, Cardiovascular Health Research Unit, University of Washington, Seattle, WA, USA.; Department of Health Services, Cardiovascular Health Research Unit, University of Washington, Seattle, WA, USA., Qi L; Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA, USA., Raffel LJ; Department of Pediatrics, Genetic and Genomic Medicine, University of California, Irvine, Irvine, CA, USA., Rauramaa R; Foundation for Research in Health Exercise and Nutrition, Kuopio Research Institute of Exercise Medicine, Kuopio, Finland., Redline S; Department of Medicine, Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, MA, USA.; Department of Medicine, Sleep Medicine, Harvard Medical School, Boston, MA, USA., Ridker PM; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Havard Medical School, Boston, MA, USA., Rosendaal FR; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands., Saaristo TE; Tampere, Finnish Diabetes Association, Tampere, Finland.; Pirkanmaa Hospital District, Tampere, Finland., Sandhu M; Department of Medicine, University of Cambridge, Cambridge, UK., Saramies J; South Karelia Central Hospital, Lappeenranta, Finland., Schneiderman N; Department of Psychology, University of Miami, Miami, FL, USA., Schwarz P; German Center for Diabetes Research (DZD), Neuherberg, Germany.; Department for Prevention and Care of Diabetes, Faculty of Medicine Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.; Paul Langerhans Institute Dresden of the Helmholtz Center Munich, University Hospital and Faculty of Medicine, Dresden, Germany., Scott LJ; Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA.; Department of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, MI, USA., Selvin E; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA., Sever P; National Heart and Lung Institute, Imperial College London, London, UK., Shu XO; Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University Medical Center, Nashville, TN, USA., Slagboom PE; Department of Biomedical Data Sciences, Molecular Epidemiology, Leiden University Medical Center, Leiden, the Netherlands., Small KS; Department of Twin Research and Genetic Epidemiology, School of Life Course Sciences, King's College London, London, UK., Smith BH; Division of Population Health and Genomics, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK., Snieder H; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Sofer T; Department of Medicine, Harvard Medical School, Boston, MA, USA.; Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, MA, USA., Sørensen TIA; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.; Department of Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Department of Public Health, Section of Epidemiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Spector TD; Department of Twin Research and Genetic Epidemiology, School of Life Course Sciences, King's College London, London, UK., Stanton A; Department of Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland, Dublin, Ireland., Steves CJ; Department of Twin Research and Genetic Epidemiology, School of Life Course Sciences, King's College London, London, UK.; Department of Ageing and Health, Guy's and St Thomas' NHS Foundation Trust, London, UK., Stumvoll M; Medical Department III-Endocrinology, Nephrology, Rheumatology, University of Leipzig Medical Center, Leipzig, Germany., Sun L; CAS Key Laboratory of Nutrition, Metabolism and Food Safety, Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China., Tabara Y; Center for Genomic Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan., Tai ES; Saw Swee Hock School of Public Health, National Univeristy of Singapore and National University Health System, Singapore, Singapore.; Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore, Singapore.; Cardiovascular and Metabolic Disease Signature Research Program, Duke-NUS Medical School, Singapore, Singapore., Timpson NJ; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.; Department of Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Tönjes A; Medical Department III-Endocrinology, Nephrology, Rheumatology, University of Leipzig Medical Center, Leipzig, Germany., Tuomilehto J; Department of Public Health Solutions, National Institute for Health and Welfare, Helsinki, Finland.; Department of Public Health, University of Helsinki, Helsinki, Finland.; Saudi Diabetes Research Group, King Abdulaziz University, Jeddah, Saudi Arabia., Tusie T; Molecular Biology and Genomic Medicine Unit, National Institute of Medical Sciences and Nutrition, Mexico City, Mexico.; Department of Genomic Medicine and Environmental Toxicology, Instituto de Investigaciones Biomedicas, Universidad Nacional Autonoma de Mexico, Mexico City, Mexico., Uusitupa M; Department of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland., van der Harst P; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.; Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., van Duijn C; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.; Nuffield Department of Population Health, University of Oxford, Oxford, UK., Vitart V; Medical Research Council Human Genetics Unit, Institute for Genetics and Cancer, University of Edinburgh, Edinburgh, UK., Vollenweider P; Department of Medicine, Internal Medicine, Lausanne University Hospital (CHUV), Lausanne, Switzerland., Vrijkotte TGM; Department of Public Health, Amsterdam Public Health Research Institute, Amsterdam University Medical Center, Amsterdam, the Netherlands., Wagenknecht LE; Department of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, NC, USA., Walker M; Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK., Wang YX; Beijing Institute of Ophthalmology, Beijing Ophthalmology and Visual Science Key Lab, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing, China., Wareham NJ; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, UK., Watanabe RM; Department of Preventive Medicine, Keck School of Medicine of University of Southern California, Los Angeles, CA, USA.; University of Southern California Diabetes and Obesity Research Institute, Keck School of Medicine of University of Southern California, Los Angeles, CA, USA.; Department of Physiology and Neuroscience, Keck School of Medicine of University of Southern California, Los Angeles, CA, USA., Watkins H; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Wei WB; Beijing Tongren Eye Center, Beijing Key Laboratory of Intraocular Tumor Diagnosis and Treatment, Beijing Ophthalmology & Visual Sciences Key Lab, Beijing Tongren Hospital, Capital Medical University, Beijing, China., Wickremasinghe AR; Department of Public Health, Faculty of Medicine, University of Kelaniya, Ragama, Sri Lanka., Willemsen G; Department of Biological Psychology, Faculty of Behaviour and Movement Sciences, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.; Amsterdam Public Health Research Institute, Amsterdam University Medical Center, Amsterdam, the Netherlands., Wilson JF; Centre for Global Health Research, Usher Institute, University of Edinburgh, Edinburgh, UK.; Medical Research Council Human Genetics Unit, Institute for Genetics and Cancer, University of Edinburgh, Edinburgh, UK., Wong TY; Ocular Epidemiology, Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore.; Ophthalmology & Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore, Singapore., Wu JY; Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan., Xiang AH; Department of Research and Evaluation, Kaiser Permanente of Southern California, Pasadena, CA, USA., Yanek LR; Department of Medicine, General Internal Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Yengo L; Institute for Molecular Bioscience, The University of Queensland, St Lucia, Queensland, Australia., Yokota M; Kurume University School of Medicine, Kurume, Japan., Zeggini E; Department of Human Genetics, Wellcome Sanger Institute, Cambridge, UK.; Institute of Translational Genomics, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; TUM School of Medicine, Technical University of Munich and Klinikum Rechts der Isar, Munich, Germany., Zheng W; Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University Medical Center, Nashville, TN, USA., Zonderman AB; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA., Rotter JI; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Gloyn AL; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.; Oxford NIHR Biomedical Research Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.; Department of Pediatrics, Division of Endocrinology, Stanford School of Medicine, Stanford, CA, USA., McCarthy MI; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.; Oxford NIHR Biomedical Research Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Genentech, South San Francisco, CA, USA., Dupuis J; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Meigs JB; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA.; Department of Medicine, Division of General Internal Medicine, Massachusetts General Hospital, Boston, MA, USA., Scott RA; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, UK., Prokopenko I; Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK.; Section of Statistical Multi-omics, Department of Clinical and Experimental Research, University of Surrey, Guildford, UK., Leong A; Harvard Medical School, Boston, MA, USA.; Department of Medicine, General Internal Medicine, Massachusetts General Hospital, Boston, MA, USA.; Department of Medicine, Diabetes Unit and Endocrine Unit, Massachusetts General Hospital, Boston, MA, USA., Liu CT; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Parker SCJ; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA.; Department of Human Genetics, University of Michigan, Ann Arbor, MI, USA., Mohlke KL; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA., Langenberg C; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, UK., Wheeler E; Department of Human Genetics, Wellcome Sanger Institute, Cambridge, UK.; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, UK., Morris AP; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.; Centre for Genetics and Genomics Versus Arthritis, Division of Musculoskeletal and Dermatological Sciences, The University of Manchester, Manchester, UK.; Centre for Musculoskeletal Research, Division of Musculoskeletal and Dermatological Sciences, The University of Manchester, Manchester, UK.; Department of Biostatistics, University of Liverpool, Liverpool, UK., Barroso I; Exeter Centre of Excellence for Diabetes Research (EXCEED), Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, UK. ines.barroso@exeter.ac.uk.; Department of Human Genetics, Wellcome Sanger Institute, Cambridge, UK. ines.barroso@exeter.ac.uk.; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, UK. ines.barroso@exeter.ac.uk.
Publikováno v:
Nature genetics [Nat Genet] 2021 Jun; Vol. 53 (6), pp. 840-860. Date of Electronic Publication: 2021 May 31.
Autor:
Peng F; CAS Key Laboratory of Genomic and Precision Medicine, Beijing Institute of Genomic, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Beijing, People's Republic of China., Zhu G; Queensland Institute of Medical Research Berghofer Medical Research Institute, Brisbane, Australia., Hysi PG; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., Eller RJ; Department of Biology, Indiana University-Purdue University Indianapolis, Indianapolis, Indiana, USA., Chen Y; CAS Key Laboratory of Genomic and Precision Medicine, Beijing Institute of Genomic, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Beijing, People's Republic of China., Li Y; CAS Key Laboratory of Genomic and Precision Medicine, Beijing Institute of Genomic, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Beijing, People's Republic of China., Hamer MA; Department of Dermatology, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands., Zeng C; CAS Key Laboratory of Genomic and Precision Medicine, Beijing Institute of Genomic, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Beijing, People's Republic of China., Hopkins RL; Department of Biology, Indiana University-Purdue University Indianapolis, Indianapolis, Indiana, USA., Jacobus CL; Department of Biology, Indiana University-Purdue University Indianapolis, Indianapolis, Indiana, USA., Wallace PL; Department of Biology, Indiana University-Purdue University Indianapolis, Indianapolis, Indiana, USA., Uitterlinden AG; Department of Internal Medicine, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands; Department of Epidemiology, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands., Ikram MA; Department of Epidemiology, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands., Nijsten T; Department of Dermatology, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands., Duffy DL; Queensland Institute of Medical Research Berghofer Medical Research Institute, Brisbane, Australia., Medland SE; Queensland Institute of Medical Research Berghofer Medical Research Institute, Brisbane, Australia., Spector TD; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., Walsh S; Department of Biology, Indiana University-Purdue University Indianapolis, Indianapolis, Indiana, USA., Martin NG; Queensland Institute of Medical Research Berghofer Medical Research Institute, Brisbane, Australia., Liu F; CAS Key Laboratory of Genomic and Precision Medicine, Beijing Institute of Genomic, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Beijing, People's Republic of China; Department of Genetic Identification, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands. Electronic address: f.liu@erasmusmc.nl., Kayser M; Department of Genetic Identification, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands. Electronic address: m.kayser@erasmusmc.nl.
Publikováno v:
The Journal of investigative dermatology [J Invest Dermatol] 2019 Jul; Vol. 139 (7), pp. 1601-1605. Date of Electronic Publication: 2019 Jan 28.
Autor:
Duffy DL; QIMR Berghofer Medical Research Institute, Brisbane, Australia. David.Duffy@qimrberghofer.edu.au., Zhu G; QIMR Berghofer Medical Research Institute, Brisbane, Australia., Li X; Department of Epidemiology, Richard M. Fairbanks School of Public Health, Melvin and Bren Simon Cancer Center, Indiana University, Indianapolis, IN, 63110, USA., Sanna M; Department of Twin Research & Genetic Epidemiology, St Thomas Hospital Campus, Kings College, London, UK., Iles MM; Section of Epidemiology and Biostatistics, Leeds Institute of Cancer and Pathology, University of Leeds, Leeds, UK., Jacobs LC; Department of Dermatology, Erasmus MC, University Medical Centre Rotterdam, Rotterdam, The Netherlands., Evans DM; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.; University of Queensland Diamantina Institute, Translational Research Institute, Brisbane, Australia., Yazar S; Centre for Ophthalmology and Vision Science, University of Western Australia and the Lions Eye Institute, Perth, Australia., Beesley J; QIMR Berghofer Medical Research Institute, Brisbane, Australia., Law MH; QIMR Berghofer Medical Research Institute, Brisbane, Australia., Kraft P; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, 02115, MA, USA., Visconti A; Department of Twin Research & Genetic Epidemiology, St Thomas Hospital Campus, Kings College, London, UK., Taylor JC; Section of Epidemiology and Biostatistics, Leeds Institute of Cancer and Pathology, University of Leeds, Leeds, UK., Liu F; Department of Genetic Identification, Erasmus MC, University Medical Centre Rotterdam, Rotterdam, The Netherlands., Wright MJ; QIMR Berghofer Medical Research Institute, Brisbane, Australia., Henders AK; QIMR Berghofer Medical Research Institute, Brisbane, Australia.; Institute for Molecular Bioscience, The University of Queensland, Brisbane, Australia., Bowdler L; QIMR Berghofer Medical Research Institute, Brisbane, Australia., Glass D; Department of Twin Research & Genetic Epidemiology, St Thomas Hospital Campus, Kings College, London, UK., Ikram MA; Department of Epidemiology, Erasmus MC, Rotterdam, Netherlands., Uitterlinden AG; Department of Epidemiology, Erasmus MC, Rotterdam, Netherlands.; Department of Internal Medicine, Erasmus MC, Rotterdam, Netherlands., Madden PA; Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, 63110, USA., Heath AC; Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, 63110, USA., Nelson EC; Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, 63110, USA., Green AC; QIMR Berghofer Medical Research Institute, Brisbane, Australia.; Molecular Oncology Group, CRUK Manchester Institute, University of Manchester, Manchester, UK., Chanock S; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA., Barrett JH; Section of Epidemiology and Biostatistics, Leeds Institute of Cancer and Pathology, University of Leeds, Leeds, UK., Brown MA; University of Queensland Diamantina Institute, Translational Research Institute, Brisbane, Australia., Hayward NK; QIMR Berghofer Medical Research Institute, Brisbane, Australia., MacGregor S; QIMR Berghofer Medical Research Institute, Brisbane, Australia., Sturm RA; Dermatology Research Centre, University of Queensland Diamantina Institute, Translational Research Institute, Brisbane, Australia., Hewitt AW; Centre for Ophthalmology and Vision Science, University of Western Australia and the Lions Eye Institute, Perth, Australia., Kayser M; Department of Genetic Identification, Erasmus MC, University Medical Centre Rotterdam, Rotterdam, The Netherlands., Hunter DJ; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, 02115, MA, USA., Newton Bishop JA; Section of Epidemiology and Biostatistics, Leeds Institute of Cancer and Pathology, University of Leeds, Leeds, UK., Spector TD; Department of Twin Research & Genetic Epidemiology, St Thomas Hospital Campus, Kings College, London, UK., Montgomery GW; QIMR Berghofer Medical Research Institute, Brisbane, Australia.; Institute for Molecular Bioscience, The University of Queensland, Brisbane, Australia., Mackey DA; Centre for Ophthalmology and Vision Science, University of Western Australia and the Lions Eye Institute, Perth, Australia., Smith GD; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK., Nijsten TE; Department of Dermatology, Erasmus MC, University Medical Centre Rotterdam, Rotterdam, The Netherlands., Bishop DT; Section of Epidemiology and Biostatistics, Leeds Institute of Cancer and Pathology, University of Leeds, Leeds, UK., Bataille V; Department of Twin Research & Genetic Epidemiology, St Thomas Hospital Campus, Kings College, London, UK., Falchi M; Department of Twin Research & Genetic Epidemiology, St Thomas Hospital Campus, Kings College, London, UK., Han J; Department of Epidemiology, Richard M. Fairbanks School of Public Health, Melvin and Bren Simon Cancer Center, Indiana University, Indianapolis, IN, 63110, USA., Martin NG; QIMR Berghofer Medical Research Institute, Brisbane, Australia.
Publikováno v:
Nature communications [Nat Commun] 2018 Nov 14; Vol. 9 (1), pp. 4774. Date of Electronic Publication: 2018 Nov 14.
Autor:
Visconti A; Department of Twin Research and Genetic Epidemiology, King's College London, London, SE1 7EH, UK., Duffy DL; QIMR Berghofer Medical Research Institute, Brisbane, 4029, Australia., Liu F; CAS Key Laboratory of Genomic and Precision Medicine, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, 100101, China.; University of Chinese Academy of Sciences, Beijing, 100049, China.; Department of Genetic Identification, Erasmus MC University Medical Center Rotterdam, Rotterdam, 3000 CA, The Netherlands., Zhu G; QIMR Berghofer Medical Research Institute, Brisbane, 4029, Australia., Wu W; Department of Epidemiology, Richard M. Fairbanks School of Public Health, Melvin & Bren Simon Cancer Center, Indiana University, Indianapolis, 46202, IN, USA., Chen Y; CAS Key Laboratory of Genomic and Precision Medicine, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, 100101, China.; University of Chinese Academy of Sciences, Beijing, 100049, China., Hysi PG; Department of Twin Research and Genetic Epidemiology, King's College London, London, SE1 7EH, UK., Zeng C; CAS Key Laboratory of Genomic and Precision Medicine, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, 100101, China., Sanna M; Department of Twin Research and Genetic Epidemiology, King's College London, London, SE1 7EH, UK., Iles MM; Section of Epidemiology and Biostatistics, Leeds Institute of Cancer and Pathology, University of Leeds, Leeds, LS9 7TF, UK., Kanetsky PA; Department of Cancer Epidemiology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, 33612, FL, USA., Demenais F; INSERM, UMR 946, Genetic Variation and Human Diseases Unit, Paris, 75010, France.; Institut Universitaire d'Hématologie, Université Paris Diderot, Sorbonne Paris Cité, Paris, 75010, France., Hamer MA; Department of Dermatology, Erasmus MC University Medical Center Rotterdam, Rotterdam, 3000 CA, The Netherlands., Uitterlinden AG; Department of Internal Medicine, Erasmus MC University Medical Center Rotterdam, Rotterdam, 3000 CA, The Netherlands.; Department of Epidemiology, Erasmus MC University Medical Center Rotterdam, Rotterdam, 3000 CA, The Netherlands., Ikram MA; Department of Epidemiology, Erasmus MC University Medical Center Rotterdam, Rotterdam, 3000 CA, The Netherlands., Nijsten T; Department of Dermatology, Erasmus MC University Medical Center Rotterdam, Rotterdam, 3000 CA, The Netherlands., Martin NG; QIMR Berghofer Medical Research Institute, Brisbane, 4029, Australia., Kayser M; Department of Genetic Identification, Erasmus MC University Medical Center Rotterdam, Rotterdam, 3000 CA, The Netherlands., Spector TD; Department of Twin Research and Genetic Epidemiology, King's College London, London, SE1 7EH, UK., Han J; Department of Epidemiology, Richard M. Fairbanks School of Public Health, Melvin & Bren Simon Cancer Center, Indiana University, Indianapolis, 46202, IN, USA.; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, 02115, MA, USA., Bataille V; Department of Twin Research and Genetic Epidemiology, King's College London, London, SE1 7EH, UK.; Department of Dermatology, West Herts NHS Trust, Herts, HP2 4AD, UK., Falchi M; Department of Twin Research and Genetic Epidemiology, King's College London, London, SE1 7EH, UK. mario.falchi@kcl.ac.uk.
Publikováno v:
Nature communications [Nat Commun] 2018 May 08; Vol. 9 (1), pp. 1684. Date of Electronic Publication: 2018 May 08.
Autor:
Hysi PG; King's College London Department of Twins Research and Genetic Epidemiology, London, UK.; Department of Ophthalmology, King's College London, London, UK., Valdes AM; King's College London Department of Twins Research and Genetic Epidemiology, London, UK.; Division of Rheumatology, Orthopaedics and Dermatology, School of Medicine, University of Nottingham, Nottingham, UK.; Nottingham NIHR Biomedical Research Centre, Nottingham, United Kingdom., Liu F; CAS Key Laboratory of Genomic and Precision Medicine, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, PR China.; University of Chinese Academy of Sciences, Beijing, PR China.; Department of Genetic Identification, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands., Furlotte NA; 23andMe, Inc., Mountain View, CA, USA., Evans DM; University of Queensland Diamantina Institute, Translational Research Institute, Brisbane, QLD, Australia.; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK., Bataille V; King's College London Department of Twins Research and Genetic Epidemiology, London, UK., Visconti A; King's College London Department of Twins Research and Genetic Epidemiology, London, UK., Hemani G; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK., McMahon G; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK., Ring SM; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK., Smith GD; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK., Duffy DL; QIMR Berghofer Medical Research Institute, Brisbane, Australia., Zhu G; QIMR Berghofer Medical Research Institute, Brisbane, Australia., Gordon SD; QIMR Berghofer Medical Research Institute, Brisbane, Australia., Medland SE; QIMR Berghofer Medical Research Institute, Brisbane, Australia., Lin BD; Netherlands Twin Register, Department of Biological Psychology, Vrije Universiteit, Amsterdam, The Netherlands., Willemsen G; Netherlands Twin Register, Department of Biological Psychology, Vrije Universiteit, Amsterdam, The Netherlands., Jan Hottenga J; Netherlands Twin Register, Department of Biological Psychology, Vrije Universiteit, Amsterdam, The Netherlands., Vuckovic D; Department of Medicine, Surgery and Health Sciences, University of Trieste, Trieste, Italy., Girotto G; Department of Medicine, Surgery and Health Sciences, University of Trieste, Trieste, Italy.; Institute for Maternal and Child Health IRCCS 'Burlo Garofolo', Trieste, Italy., Gandin I; Department of Medicine, Surgery and Health Sciences, University of Trieste, Trieste, Italy., Sala C; Department of Medicine, Surgery and Health Sciences, University of Trieste, Trieste, Italy., Concas MP; Institute for Maternal and Child Health IRCCS 'Burlo Garofolo', Trieste, Italy., Brumat M; Department of Medicine, Surgery and Health Sciences, University of Trieste, Trieste, Italy., Gasparini P; Department of Medicine, Surgery and Health Sciences, University of Trieste, Trieste, Italy.; Institute for Maternal and Child Health IRCCS 'Burlo Garofolo', Trieste, Italy., Toniolo D; Division of Genetics and Cell Biology, San Faffaele Research Institute, Milano, Italy., Cocca M; Institute for Maternal and Child Health IRCCS 'Burlo Garofolo', Trieste, Italy., Robino A; Institute for Maternal and Child Health IRCCS 'Burlo Garofolo', Trieste, Italy., Yazar S; Centre for Ophthalmology and Visual Science, University of Western Australia, Lions Eye Institute, Perth, WA, Australia.; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, UK., Hewitt AW; Centre for Ophthalmology and Visual Science, University of Western Australia, Lions Eye Institute, Perth, WA, Australia.; Centre for Eye Research Australia, University of Melbourne, Department of Ophthalmology, Royal Victorian Eye and Ear Hospital, Melbourne, Australia.; School of Medicine, Menzies Research Institute Tasmania, University of Tasmania, Hobart, Australia., Chen Y; CAS Key Laboratory of Genomic and Precision Medicine, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, PR China.; University of Chinese Academy of Sciences, Beijing, PR China., Zeng C; CAS Key Laboratory of Genomic and Precision Medicine, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, PR China., Uitterlinden AG; Department of Internal Medicine, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands.; Department of Epidemiology, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands., Ikram MA; Department of Epidemiology, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands., Hamer MA; Department of Dermatology, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands., van Duijn CM; Department of Epidemiology, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands., Nijsten T; Department of Dermatology, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands., Mackey DA; Centre for Ophthalmology and Visual Science, University of Western Australia, Lions Eye Institute, Perth, WA, Australia.; Centre for Eye Research Australia, University of Melbourne, Department of Ophthalmology, Royal Victorian Eye and Ear Hospital, Melbourne, Australia.; School of Medicine, Menzies Research Institute Tasmania, University of Tasmania, Hobart, Australia., Falchi M; King's College London Department of Twins Research and Genetic Epidemiology, London, UK., Boomsma DI; Netherlands Twin Register, Department of Biological Psychology, Vrije Universiteit, Amsterdam, The Netherlands., Martin NG; QIMR Berghofer Medical Research Institute, Brisbane, Australia., Hinds DA; 23andMe, Inc., Mountain View, CA, USA., Kayser M; Department of Genetic Identification, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands. m.kayser@erasmusmc.nl., Spector TD; King's College London Department of Twins Research and Genetic Epidemiology, London, UK. tim.spector@kcl.ac.uk.
Publikováno v:
Nature genetics [Nat Genet] 2018 May; Vol. 50 (5), pp. 652-656. Date of Electronic Publication: 2018 Apr 16.
Autor:
Macé A; Institute of Social and Preventive Medicine, Lausanne University Hospital, Lausanne, 1010, Switzerland.; Swiss Institute of Bioinformatics, Lausanne, 1015, Switzerland.; Department of Computational Biology, University of Lausanne, Lausanne, 1011, Switzerland., Tuke MA; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, EX2 5DW, UK., Deelen P; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, 9713 GZ, The Netherlands.; University of Groningen, University Medical Center Groningen, Genomics Coordination Center, Groningen, 9713 GZ, The Netherlands., Kristiansson K; National Institute for Health and Welfare, Helsinki, 00271, Finland.; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, FI-00014, Finland., Mattsson H; National Institute for Health and Welfare, Helsinki, 00271, Finland.; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, FI-00014, Finland., Nõukas M; Estonian Genome Center, University of Tartu, Tartu, 51010, Estonia.; Institute of Molecular and Cell Biology, University of Tartu, Tartu, 51010, Estonia., Sapkota Y; QIMR Berghofer Medical Research Institute, Brisbane, 4006, Australia.; St. Jude Children's Research hospital, Memphis, TN, 38105, USA., Schick U; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA., Porcu E; Swiss Institute of Bioinformatics, Lausanne, 1015, Switzerland.; Center for Integrative Genomics, University of Lausanne, Lausanne, 1015, Switzerland., Rüeger S; Institute of Social and Preventive Medicine, Lausanne University Hospital, Lausanne, 1010, Switzerland.; Swiss Institute of Bioinformatics, Lausanne, 1015, Switzerland., McDaid AF; Institute of Social and Preventive Medicine, Lausanne University Hospital, Lausanne, 1010, Switzerland.; Swiss Institute of Bioinformatics, Lausanne, 1015, Switzerland., Porteous D; Generation Scotland, Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, EH4 2XU, UK., Winkler TW; Department of Genetic Epidemiology, University of Regensburg, Regensburg, 93053, Germany., Salvi E; Department of Health Sciences, University of Milano, Milano, 20090, Italy., Shrine N; Department of Health Sciences, University of Leicester, Leicester, LE1 7RH, UK., Liu X; Department of Epidemiology Research, Statens Serum Institut, Copenhagen, 2300, Denmark., Ang WQ; School of Women's and Infants' Health, The University of Western Australia, Perth, 6009, Australia., Zhang W; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, Norfolk Place, London, W2 1PG, UK.; Department of Cardiology, Ealing Hospital NHS Trust, Uxbridge Road, Southall, Middlesex, UB1 3EU, UK., Feitosa MF; Department of Genetics, Washington University School of Medicine, St. Louis, 63108, USA., Venturini C; Department of Twin Research and Genetic Epidemiology, King's College London, London, SE1 7EH, UK., van der Most PJ; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, 9713 GZ, The Netherlands., Rosengren A; Research Institute of Biological Psychiatry, Mental Health Center Sct. Hans, Roskilde, 4000, Denmark.; iPSYCH, The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, 8210, Denmark., Wood AR; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, EX2 5DW, UK., Beaumont RN; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, EX2 5DW, UK., Jones SE; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, EX2 5DW, UK., Ruth KS; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, EX2 5DW, UK., Yaghootkar H; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, EX2 5DW, UK., Tyrrell J; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, EX2 5DW, UK., Havulinna AS; National Institute for Health and Welfare, Helsinki, 00271, Finland., Boers H; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, 9713 GZ, The Netherlands.; University of Groningen, University Medical Center Groningen, Genomics Coordination Center, Groningen, 9713 GZ, The Netherlands., Mägi R; Estonian Genome Center, University of Tartu, Tartu, 51010, Estonia., Kriebel J; Research Unit of Molecular Epidemiology, Helmholtz Zentrum Muenchen, German Research Center for Environmental Health, Neuherberg, 85764, Germany.; Institute of Epidemiology II, Helmholtz Zentrum Muenchen, German Research Center for Environmental Health, Neuherberg, 85764, Germany.; German Center for Diabetes Research (DZD), Muenchen-Neuherberg, 85764, Germany., Müller-Nurasyid M; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, 85764, Germany.; Department of Medicine I, Ludwig-Maximilians-Universität, Munich, 81337, Germany.; DZHK (German Centre for Cardiovascular Research), Partner Site Munich Heart Alliance, Munich, 80336, Germany., Perola M; National Institute for Health and Welfare, Helsinki, 00271, Finland.; University of Tartu, Estonian Genome Center, Tartu, 51010, Estonia., Nieminen M; Heart and Lung Centre HUCH and Helsinki University, Helsinki, 00029, Finland., Lokki ML; Medicum, Helsinki University, Helsinki, 00014, Finland., Kähönen M; Department of Clinical Physiology, Tampere University Hospital, Tampere, 33521, Finland.; Department of Clinical Physiology, University of Tampere Faculty of Medicine and Life Sciences, Tampere, 33521, Finland., Viikari JS; Division of Medicine, Turku University Hospital, Turku, 20521, Finland.; Department of Medicine, University of Turku, Turku, 20521, Finland., Geller F; Department of Epidemiology Research, Statens Serum Institut, Copenhagen, 2300, Denmark., Lahti J; Department of Psychology and Logopedics, Faculty of Medicine, University of Helsinki, Helsinki, 00014, Finland.; Helsinki Collegium for Advanced Studies, University of Helsinki, Helsinki, 00014, Finland., Palotie A; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, FI-00014, Finland.; The Stanley Center for Psychiatric Research, The Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.; Analytic and Translational Genetics Unit, Department of Medicine and Psychiatric & Neurodevelopmental Genetics Unit, Massachusetts General Hospital, Boston, MA, 02114, USA., Koponen P; National Institute for Health and Welfare, Helsinki, 00271, Finland., Lundqvist A; National Institute for Health and Welfare, Helsinki, 00271, Finland., Rissanen H; National Institute for Health and Welfare, Helsinki, 00271, Finland., Bottinger EP; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA., Afaq S; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, Norfolk Place, London, W2 1PG, UK., Wojczynski MK; Department of Genetics, Washington University School of Medicine, St. Louis, 63108, USA., Lenzini P; Department of Genetics, Washington University School of Medicine, St. Louis, 63108, USA., Nolte IM; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, 9713 GZ, The Netherlands., Sparsø T; Research Institute of Biological Psychiatry, Mental Health Center Sct. Hans, Roskilde, 4000, Denmark.; iPSYCH, The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, 8210, Denmark., Schupf N; Taub Institute, College of Physicians and Surgeons, Columbia University, New York, NY, 10032, USA., Christensen K; The Danish Aging Research Center, Epidemiology, University of Southern Denmark, Odense, 5000, Denmark., Perls TT; Section of Geriatrics, Department of Medicine, Boston University, Boston School of Medicine and Boston Medical Center, Boston, MA, 02118, USA., Newman AB; Department of Epidemiology, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA, 15261, USA., Werge T; Research Institute of Biological Psychiatry, Mental Health Center Sct. Hans, Roskilde, 4000, Denmark.; iPSYCH, The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, 8210, Denmark.; Institute of Clinical Sciences, Faculty of Medicine and Health Sciences, University of Copenhagen, Copenhagen, 2200, Denmark., Snieder H; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, 9713 GZ, The Netherlands., Spector TD; Department of Twin Research and Genetic Epidemiology, King's College London, London, SE1 7EH, UK., Chambers JC; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, Norfolk Place, London, W2 1PG, UK.; Department of Cardiology, Ealing Hospital NHS Trust, Uxbridge Road, Southall, Middlesex, UB1 3EU, UK.; Imperial College Healthcare NHS Trust, London, W12 0HS, UK., Koskinen S; National Institute for Health and Welfare, Helsinki, 00271, Finland., Melbye M; Department of Epidemiology Research, Statens Serum Institut, Copenhagen, 2300, Denmark.; Department of Clinical Medicine, University of Copenhagen, Copenhagen, 2200, Denmark.; Department of Medicine, Stanford University School of Medicine, Stanford, CA, 94305, USA., Raitakari OT; Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, 20521, Finland.; Research Center of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, 20521, Finland., Lehtimäki T; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, 33521, Finland.; Department of Clinical Chemistry, University of Tampere Faculty of Medicine and Life Sciences, Tampere, 33521, Finland., Tobin MD; Department of Health Sciences, University of Leicester, Leicester, LE1 7RH, UK.; National Institute for Health Research, Leicester Respiratory Biomedical Research Unit, Glenfield Hospital, Leicester, LE3 9QP, UK., Wain LV; Department of Health Sciences, University of Leicester, Leicester, LE1 7RH, UK.; National Institute for Health Research, Leicester Respiratory Biomedical Research Unit, Glenfield Hospital, Leicester, LE3 9QP, UK., Sinisalo J; Heart and Lung Centre HUCH and Helsinki University, Helsinki, 00029, Finland., Peters A; Institute of Epidemiology II, Helmholtz Zentrum Muenchen, German Research Center for Environmental Health, Neuherberg, 85764, Germany.; German Center for Diabetes Research (DZD), Muenchen-Neuherberg, 85764, Germany.; DZHK (German Centre for Cardiovascular Research), Partner Site Munich Heart Alliance, Munich, 80336, Germany., Meitinger T; Institute of Human Genetics, Helmholtz Zentrum München, Neuherberg, 85764, Germany.; Institute of Human Genetics, Technische Universität München, Munich, 81675, Germany., Martin NG; QIMR Berghofer Medical Research Institute, Brisbane, QLD, 4006, Australia., Wray NR; Queensland Brain Institute, University of Queensland, Brisbane, QLD, 4072, Australia., Montgomery GW; QIMR Berghofer Medical Research Institute, Brisbane, 4006, Australia.; The Institute for Molecular Bioscience, University of Queensland, Brisbane, QLD, 4072, Australia., Medland SE; QIMR Berghofer Medical Research Institute, Brisbane, 4006, Australia., Swertz MA; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, 9713 GZ, The Netherlands.; University of Groningen, University Medical Center Groningen, Genomics Coordination Center, Groningen, 9713 GZ, The Netherlands., Vartiainen E; National Institute for Health and Welfare, Helsinki, 00271, Finland., Borodulin K; National Institute for Health and Welfare, Helsinki, 00271, Finland., Männistö S; National Institute for Health and Welfare, Helsinki, 00271, Finland., Murray A; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, EX2 5DW, UK., Bochud M; Institute of Social and Preventive Medicine, Lausanne University Hospital, Lausanne, 1010, Switzerland., Jacquemont S; Centre de recherche, Centre Hospitalier Universitaire Sainte Justine, Montréal, Canada, H3T 1C5.; Service of Medical Genetics, University Hospital of Lausanne, University of Lausanne, Lausanne, 1011, Switzerland., Rivadeneira F; Department of Epidemiology, Erasmus Medical Center, Rotterdam, 3015 GE, The Netherlands.; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, 3015 GE, The Netherlands., Hansen TF; Research Institute of Biological Psychiatry, Mental Health Center Sct. Hans, Roskilde, 4000, Denmark.; iPSYCH, The Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, 8210, Denmark., Oldehinkel AJ; Department of Psychiatry, University of Groningen, University Medical Center Groningen, Groningen, 9713 GZ, The Netherlands., Mangino M; Department of Twin Research and Genetic Epidemiology, King's College London, London, SE1 7EH, UK.; NIHR Biomedical Research Centre at Guy's and St Thomas' Foundation Trust, London, SE1 9RT, UK., Province MA; Department of Genetics, Washington University School of Medicine, St. Louis, 63108, USA., Deloukas P; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, EC1M 6BQ, UK.; Princess Al-Jawhara Al-Brahim Centre of Excellence in Research of Hereditary Disorders (PACER-HD), King Abdulaziz University, Jeddah, 21589, Saudi Arabia., Kooner JS; Department of Cardiology, Ealing Hospital NHS Trust, Uxbridge Road, Southall, Middlesex, UB1 3EU, UK.; Imperial College Healthcare NHS Trust, London, W12 0HS, UK.; National Heart and Lung Institute, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London, W12 0NN, UK., Freathy RM; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, EX2 5DW, UK., Pennell C; School of Women's and Infants' Health, The University of Western Australia, Perth, 6009, Australia., Feenstra B; Department of Epidemiology Research, Statens Serum Institut, Copenhagen, 2300, Denmark., Strachan DP; Population Health Research Institute, St. George's, University of London, London, SW17 0RE, UK., Lettre G; Montreal Heart Institute, Université de Montréal, Montreal, QC, Canada, H1T 1C8.; Department of Medicine, Faculty of Medicine, Université de Montréal, Montreal, QC, Canada, H3T 1J4., Hirschhorn J; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.; Division of Endocrinology, Boston Children's Hospital, Harvard Medical School, Boston, MA, 02115, USA.; Department of Genetics, Harvard Medical School, Boston, MA, 02115, USA., Cusi D; Department of Health Sciences, University of Milano, Milano, 20090, Italy.; Institute of Biomedical Technologies, Italian National Research Council, Milano, 20090, Italy., Heid IM; Department of Genetic Epidemiology, University of Regensburg, Regensburg, 93053, Germany., Hayward C; Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, EH4 2XU, UK., Männik K; Estonian Genome Center, University of Tartu, Tartu, 51010, Estonia.; Center for Integrative Genomics, University of Lausanne, Lausanne, 1015, Switzerland., Beckmann JS; Swiss Institute of Bioinformatics, Lausanne, 1015, Switzerland., Loos RJF; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.; The Genetics of Obesity and Related Metabolic Traits Program, Icahn School of Medicine at Mount Sinai, New York, 10029, USA., Nyholt DR; QIMR Berghofer Medical Research Institute, Brisbane, 4006, Australia.; Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, 4059, Australia., Metspalu A; Estonian Genome Center, University of Tartu, Tartu, 51010, Estonia., Eriksson JG; Department of General Practice and Primary Health Care, University of Helsinki and Helsinki University Hospital, Helsinki, 00014, Finland.; Folkhälsan Research Center, Helsinki, 00250, Finland., Weedon MN; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, EX2 5DW, UK., Salomaa V; National Institute for Health and Welfare, Helsinki, 00271, Finland., Franke L; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, 9713 GZ, The Netherlands., Reymond A; Center for Integrative Genomics, University of Lausanne, Lausanne, 1015, Switzerland., Frayling TM; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, EX2 5DW, UK., Kutalik Z; Institute of Social and Preventive Medicine, Lausanne University Hospital, Lausanne, 1010, Switzerland. zoltan.kutalik@unil.ch.; Swiss Institute of Bioinformatics, Lausanne, 1015, Switzerland. zoltan.kutalik@unil.ch.
Publikováno v:
Nature communications [Nat Commun] 2017 Sep 29; Vol. 8 (1), pp. 744. Date of Electronic Publication: 2017 Sep 29.
Autor:
Manning A; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA.; Center for Human Genetic Research, Department of Medicine, Massachusetts General Hospital, Boston, MA.; Department of Medicine, Harvard Medical School, Boston, MA., Highland HM; Human Genetics Center, The University of Texas MD Anderson Cancer Center and The University of Texas Health Science Center at Houston Graduate School of Biomedical Sciences, Houston, TX.; Department of Epidemiology, The University of North Carolina at Chapel Hill, Chapel Hill, NC., Gasser J; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA., Sim X; Department of Biostatistics and Center for Statistical Genetics, School of Public Health, University of Michigan, Ann Arbor, MI.; Saw Swee Hock School of Public Health, National University of Singapore, Singapore., Tukiainen T; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA.; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA.; Department of Genetics, Harvard Medical School, Boston, MA., Fontanillas P; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA.; 23andMe, Mountain View, CA., Grarup N; The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Rivas MA; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, U.K., Mahajan A; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, U.K., Locke AE; Department of Biostatistics and Center for Statistical Genetics, School of Public Health, University of Michigan, Ann Arbor, MI., Cingolani P; School of Computer Science, McGill University, Montreal, Canada.; McGill University and Génome Québec Innovation Centre, Montreal, Canada., Pers TH; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA.; The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Divisions of Endocrinology and Genetics and Genomics and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, MA.; Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark., Viñuela A; Department of Twin Research & Genetic Epidemiology, King's College London, London, U.K.; Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland.; Institute of Genetics and Genomics in Geneva, University of Geneva, Geneva, Switzerland., Brown AA; Wellcome Trust Sanger Institute, Hinxton, U.K.; Norwegian Centre for Mental Disorders Research and KG Jebsen Center for Psychosis Research, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway., Wu Y; Department of Genetics, The University of North Carolina at Chapel Hill, Chapel Hill, NC., Flannick J; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA.; Department of Molecular Biology, Massachusetts General Hospital, Boston, MA., Fuchsberger C; Department of Biostatistics and Center for Statistical Genetics, School of Public Health, University of Michigan, Ann Arbor, MI., Gamazon ER; Section of Genetic Medicine, Department of Medicine, The University of Chicago, Chicago, IL.; Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands., Gaulton KJ; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, U.K.; Department of Pediatrics, University of California, San Diego, La Jolla, CA., Im HK; Section of Genetic Medicine, Department of Medicine, The University of Chicago, Chicago, IL., Teslovich TM; Department of Biostatistics and Center for Statistical Genetics, School of Public Health, University of Michigan, Ann Arbor, MI., Blackwell TW; Department of Biostatistics and Center for Statistical Genetics, School of Public Health, University of Michigan, Ann Arbor, MI., Bork-Jensen J; The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Burtt NP; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA., Chen Y; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, U.K., Green T; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA., Hartl C; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA., Kang HM; Department of Biostatistics and Center for Statistical Genetics, School of Public Health, University of Michigan, Ann Arbor, MI., Kumar A; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, U.K.; Chronic Disease Epidemiology Unit, Swiss Tropical and Public Health Institute, University of Basel, Basel, Switzerland., Ladenvall C; Diabetes and Endocrinology Unit, Department of Clinical Sciences Malmö, Lund University Diabetes Centre, Malmö, Sweden., Ma C; Department of Biostatistics and Center for Statistical Genetics, School of Public Health, University of Michigan, Ann Arbor, MI., Moutsianas L; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, U.K., Pearson RD; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, U.K., Perry JRB; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, U.K.; Genetics of Complex Traits, University of Exeter Medical School, Exeter, U.K.; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, U.K., Rayner NW; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, U.K.; Oxford Centre for Diabetes, Endocrinology & Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, U.K.; Department of Human Genetics, Wellcome Trust Sanger Institute, Hinxton, U.K., Robertson NR; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, U.K.; Oxford Centre for Diabetes, Endocrinology & Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, U.K., Scott LJ; Department of Biostatistics and Center for Statistical Genetics, School of Public Health, University of Michigan, Ann Arbor, MI., van de Bunt M; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, U.K.; Oxford Centre for Diabetes, Endocrinology & Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, U.K., Eriksson JG; Department of General Practice and Primary Health Care, University of Helsinki, Helsinki, Finland.; Unit of General Practice, Helsinki University Central Hospital, Helsinki, Finland.; Folkhälsan Research Center, Helsinki, Finland.; Vaasa Central Hospital, Vaasa, Finland.; Department of Health, National Institute for Health and Welfare, Helsinki, Finland., Jula A; Department of Health, National Institute for Health and Welfare, Helsinki, Finland., Koskinen S; Department of Health, National Institute for Health and Welfare, Helsinki, Finland., Lehtimäki T; Department of Clinical Chemistry, Fimlab Laboratories, University of Tampere School of Medicine, Tampere, Finland., Palotie A; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA.; Center for Human Genetic Research, Department of Medicine, Massachusetts General Hospital, Boston, MA.; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland., Raitakari OT; Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland.; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland., Jacobs SBR; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA., Wessel J; Department of Epidemiology, Fairbanks School of Public Health, Indianapolis, IN.; Department of Medicine, Indiana University School of Medicine, Indianapolis, IN., Chu AY; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA., Scott RA; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, U.K., Goodarzi MO; Division of Endocrinology, Diabetes & Metabolism, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA.; Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA., Blancher C; High-Throughput Genomics, Oxford Genomics Centre, Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, U.K., Buck G; High-Throughput Genomics, Oxford Genomics Centre, Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, U.K., Buck D; High-Throughput Genomics, Oxford Genomics Centre, Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, U.K., Chines PS; National Human Genome Research Institute, National Institutes of Health, Bethesda, MD., Gabriel S; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA., Gjesing AP; The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Groves CJ; Oxford Centre for Diabetes, Endocrinology & Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, U.K., Hollensted M; The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Huyghe JR; Department of Biostatistics and Center for Statistical Genetics, School of Public Health, University of Michigan, Ann Arbor, MI., Jackson AU; Department of Biostatistics and Center for Statistical Genetics, School of Public Health, University of Michigan, Ann Arbor, MI., Jun G; Department of Biostatistics and Center for Statistical Genetics, School of Public Health, University of Michigan, Ann Arbor, MI., Justesen JM; The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Mangino M; Department of Twin Research & Genetic Epidemiology, King's College London, London, U.K., Murphy J; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA., Neville M; Oxford Centre for Diabetes, Endocrinology & Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, U.K., Onofrio R; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA., Small KS; Department of Twin Research & Genetic Epidemiology, King's College London, London, U.K., Stringham HM; Department of Biostatistics and Center for Statistical Genetics, School of Public Health, University of Michigan, Ann Arbor, MI., Trakalo J; High-Throughput Genomics, Oxford Genomics Centre, Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, U.K., Banks E; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA., Carey J; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA., Carneiro MO; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA., DePristo M; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA., Farjoun Y; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA., Fennell T; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA., Goldstein JI; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA.; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA., Grant G; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA., Hrabé de Angelis M; Institute of Experimental Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; German Center for Diabetes Research (DZD), Neuherberg, Germany.; Institute of Experimental Genetics, School of Life Science Weihenstephan, Technische Universität München, Freising, Germany., Maguire J; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA., Neale BM; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA.; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA., Poplin R; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA., Purcell S; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA.; Center for Human Genetic Research, Department of Medicine, Massachusetts General Hospital, Boston, MA.; Department of Psychiatry, Icahn Institute for Genomics & Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY., Schwarzmayr T; Institute of Human Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany., Shakir K; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA., Smith JD; Department of Genome Sciences, University of Washington School of Medicine, Seattle, WA., Strom TM; Institute of Human Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Human Genetics, Technische Universität München, Neuherberg, Germany., Wieland T; Institute of Human Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany., Lindstrom J; Diabetes Prevention Unit, National Institute for Health and Welfare, Helsinki, Finland., Brandslund I; Department of Regional Health Research, University of Southern Denmark, Odense, Denmark.; Department of Clinical Biochemistry, Vejle Hospital, Vejle, Denmark., Christensen C; Department of Internal Medicine and Endocrinology, Vejle Hospital, Vejle, Denmark., Surdulescu GL; Department of Twin Research & Genetic Epidemiology, King's College London, London, U.K., Lakka TA; Department of Physiology, Institute of Biomedicine, University of Eastern Finland, Kuopio, Finland.; Kuopio Research Institute of Exercise Medicine, Kuopio, Finland.; Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, Finland., Doney ASF; Division of Cardiovascular & Diabetes Medicine, Medical Research Institute, Ninewells Hospital and Medical School, Dundee, U.K., Nilsson P; Department of Clinical Sciences, Faculty of Medicine, Lund University, Malmö, Sweden., Wareham NJ; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, U.K., Langenberg C; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, U.K., Varga TV; Department of Clinical Sciences, Lund University Diabetes Centre, and Genetic and Molecular Epidemiology Unit, Lund University, Malmö, Sweden., Franks PW; Department of Clinical Sciences, Lund University Diabetes Centre, and Genetic and Molecular Epidemiology Unit, Lund University, Malmö, Sweden.; Department of Nutrition, Harvard School of Public Health, Boston, MA.; Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden., Rolandsson O; Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden., Rosengren AH; Diabetes and Endocrinology Unit, Department of Clinical Sciences Malmö, Lund University Diabetes Centre, Malmö, Sweden., Farook VS; Department of Genetics, Texas Biomedical Research Institute, San Antonio, TX., Thameem F; Department of Medicine, The University of Texas Health Science Center, San Antonio, TX., Puppala S; Department of Genetics, Texas Biomedical Research Institute, San Antonio, TX., Kumar S; Department of Genetics, Texas Biomedical Research Institute, San Antonio, TX., Lehman DM; Department of Medicine, The University of Texas Health Science Center, San Antonio, TX., Jenkinson CP; Department of Medicine, The University of Texas Health Science Center, San Antonio, TX.; Research and Development Service, South Texas Veterans Health Care System, San Antonio, TX., Curran JE; Department of Genetics, Texas Biomedical Research Institute, San Antonio, TX., Hale DE; Department of Pediatrics, The University of Texas Health Science Center, San Antonio, TX., Fowler SP; Department of Medicine, The University of Texas Health Science Center, San Antonio, TX., Arya R; Department of Pediatrics, The University of Texas Health Science Center, San Antonio, TX., DeFronzo RA; Department of Medicine, The University of Texas Health Science Center, San Antonio, TX., Abboud HE; Department of Medicine, The University of Texas Health Science Center, San Antonio, TX., Syvänen AC; Molecular Medicine and Science for Life Laboratory, Department of Medical Sciences, Uppsala University, Uppsala, Sweden., Hicks PJ; Center for Genomics and Personalized Medicine Research, Wake Forest School of Medicine, Winston-Salem, NC.; Center for Diabetes Research, Wake Forest School of Medicine, Winston-Salem, NC.; Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC., Palmer ND; Center for Genomics and Personalized Medicine Research, Wake Forest School of Medicine, Winston-Salem, NC.; Center for Diabetes Research, Wake Forest School of Medicine, Winston-Salem, NC.; Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC., Ng MCY; Center for Genomics and Personalized Medicine Research, Wake Forest School of Medicine, Winston-Salem, NC.; Center for Diabetes Research, Wake Forest School of Medicine, Winston-Salem, NC., Bowden DW; Center for Genomics and Personalized Medicine Research, Wake Forest School of Medicine, Winston-Salem, NC.; Center for Diabetes Research, Wake Forest School of Medicine, Winston-Salem, NC.; Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC., Freedman BI; Section on Nephrology, Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, NC., Esko T; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA.; Department of Genetics, Harvard Medical School, Boston, MA.; Division of Endocrinology, Boston Children's Hospital, Boston, MA.; Estonian Genome Center, University of Tartu, Tartu, Estonia., Mägi R; Estonian Genome Center, University of Tartu, Tartu, Estonia., Milani L; Estonian Genome Center, University of Tartu, Tartu, Estonia., Mihailov E; Estonian Genome Center, University of Tartu, Tartu, Estonia., Metspalu A; Estonian Genome Center, University of Tartu, Tartu, Estonia., Narisu N; National Human Genome Research Institute, National Institutes of Health, Bethesda, MD., Kinnunen L; Department of Health, National Institute for Health and Welfare, Helsinki, Finland., Bonnycastle LL; National Human Genome Research Institute, National Institutes of Health, Bethesda, MD., Swift A; National Human Genome Research Institute, National Institutes of Health, Bethesda, MD., Pasko D; Genetics of Complex Traits, University of Exeter Medical School, Exeter, U.K., Wood AR; Genetics of Complex Traits, University of Exeter Medical School, Exeter, U.K., Fadista J; Diabetes and Endocrinology Unit, Department of Clinical Sciences Malmö, Lund University Diabetes Centre, Malmö, Sweden., Pollin TI; Program in Personalized and Genomic Medicine, Department of Medicine, University of Maryland, Baltimore, MD., Barzilai N; Departments of Medicine and Genetics, Albert Einstein College of Medicine, New York, NY., Atzmon G; Departments of Medicine and Genetics, Albert Einstein College of Medicine, New York, NY.; Faculty of Natural Sciences, University of Haifa, Haifa, Israel., Glaser B; Endocrinology and Metabolism Service, Hadassah-Hebrew University Medical Center, Jerusalem, Israel., Thorand B; German Center for Diabetes Research (DZD), Neuherberg, Germany.; Institute of Epidemiology II, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany., Strauch K; Institute of Genetic Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Department of Genetic Epidemiology, Institute of Medical Informatics, Biometry and Epidemiology, Ludwig-Maximilians-Universität, Munich, Germany., Peters A; German Center for Diabetes Research (DZD), Neuherberg, Germany.; Institute of Epidemiology II, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK), Partner Site Munich Heart Alliance, Munich, Germany., Roden M; Institute of Clinical Diabetology, German Diabetes Center, Leibniz Center for Diabetes Research at Heinrich Heine University, Düsseldorf, Germany.; German Center for Diabetes Research, Partner Düsseldorf, Germany., Müller-Nurasyid M; Institute of Genetic Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Department of Genetic Epidemiology, Institute of Medical Informatics, Biometry and Epidemiology, Ludwig-Maximilians-Universität, Munich, Germany.; Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK), Partner Site Munich Heart Alliance, Munich, Germany.; Department of Medicine I, University Hospital Grosshadern, Ludwig-Maximilians-Universität, Munich, Germany., Liang L; Department of Epidemiology, Harvard School of Public Health, Boston, MA.; Department of Biostatistics, Harvard School of Public Health, Boston, MA., Kriebel J; German Center for Diabetes Research (DZD), Neuherberg, Germany.; Institute of Epidemiology II, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Research Unit Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany., Illig T; Research Unit Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Hannover Unified Biobank, Hannover Medical School, Hannover, Germany.; Institute of Human Genetics, Hannover Medical School, Hannover, Germany., Grallert H; German Center for Diabetes Research (DZD), Neuherberg, Germany.; Institute of Epidemiology II, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Research Unit Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany., Gieger C; Institute of Genetic Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany., Meisinger C; Institute of Epidemiology II, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany., Lannfelt L; Geriatrics, Department of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden., Musani SK; Jackson Heart Study, University of Mississippi Medical Center, Jackson, MS., Griswold M; Center of Biostatistics and Bioinformatics, University of Mississippi Medical Center, Jackson, MS., Taylor HA Jr; Department of Medicine, University of Mississippi Medical Center, Jackson, MS., Wilson G Sr; College of Public Services, Jackson State University, Jackson, MS., Correa A; Department of Medicine, University of Mississippi Medical Center, Jackson, MS., Oksa H; Pirkanmaa Hospital District, Tampere, Finland., Scott WR; Department of Epidemiology and Biostatistics, Imperial College London, London, U.K., Afzal U; Department of Epidemiology and Biostatistics, Imperial College London, London, U.K., Tan ST; Cardiovascular Sciences, National Heart and Lung Institute, Imperial College London, London, U.K.; Department of Cardiology, Ealing Hospital NHS Trust, Southall, U.K., Loh M; Department of Epidemiology and Biostatistics, Imperial College London, London, U.K.; Institute of Health Sciences, University of Oulu, Oulu, Finland.; Translational Laboratory in Genetic Medicine, Agency for Science, Technology and Research (A*STAR), Singapore., Chambers JC; Department of Epidemiology and Biostatistics, Imperial College London, London, U.K.; Department of Cardiology, Ealing Hospital NHS Trust, Southall, U.K.; Imperial College Healthcare NHS Trust, Imperial College London, London, U.K., Sehmi J; Cardiovascular Sciences, National Heart and Lung Institute, Imperial College London, London, U.K.; Department of Cardiology, Ealing Hospital NHS Trust, Southall, U.K., Kooner JS; Cardiovascular Sciences, National Heart and Lung Institute, Imperial College London, London, U.K., Lehne B; Department of Epidemiology and Biostatistics, Imperial College London, London, U.K., Cho YS; Department of Biomedical Science, Hallym University, Chuncheon, Republic of Korea., Lee JY; Ministry of Health and Welfare, Seoul, Republic of Korea., Han BG; Center for Genome Science, Korea National Research Institute of Health, Chungcheongbuk-do, Republic of Korea., Käräjämäki A; Vaasa Health Care Center, Vaasa, Finland.; Department of Primary Health Care, Vaasa Central Hospital, Vaasa, Finland., Qi Q; Department of Nutrition, Harvard School of Public Health, Boston, MA.; Department of Epidemiology and Population Health, Albert Einstein College of Medicine, New York, NY., Qi L; Department of Nutrition, Harvard School of Public Health, Boston, MA.; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA., Huang J; Department of Epidemiology, Harvard School of Public Health, Boston, MA., Hu FB; Department of Nutrition, Harvard School of Public Health, Boston, MA.; Department of Epidemiology, Harvard School of Public Health, Boston, MA., Melander O; Hypertension and Cardiovascular Disease, Department of Clinical Sciences, Lund University, Malmö, Sweden., Orho-Melander M; Diabetes and Cardiovascular Disease-Genetic Epidemiology, Department of Clinical Sciences, Lund University, Malmö, Sweden., Below JE; Human Genetics Center, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX., Aguilar D; Cardiovascular Division, Baylor College of Medicine, Houston, TX., Wong TY; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Liu J; Saw Swee Hock School of Public Health, National University of Singapore, Singapore.; Division of Human Genetics, Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), Singapore., Khor CC; Saw Swee Hock School of Public Health, National University of Singapore, Singapore.; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.; Division of Human Genetics, Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), Singapore.; Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Chia KS; Saw Swee Hock School of Public Health, National University of Singapore, Singapore., Lim WY; Saw Swee Hock School of Public Health, National University of Singapore, Singapore., Cheng CY; Saw Swee Hock School of Public Health, National University of Singapore, Singapore.; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.; Office of Clinical Sciences, Centre for Quantitative Medicine, Duke-NUS Graduate Medical School Singapore, Singapore., Chan E; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Tai ES; Saw Swee Hock School of Public Health, National University of Singapore, Singapore.; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.; Cardiovascular & Metabolic Disorders Program, Duke-NUS Graduate Medical School Singapore, Singapore., Aung T; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Linneberg A; Research Centre for Prevention and Health, Glostrup University Hospital, Glostrup, Denmark.; Department of Clinical Experimental Research, Rigshospitalet, Glostrup, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Isomaa B; Folkhälsan Research Center, Helsinki, Finland.; Department of Social Services and Health Care, Jakobstad, Finland., Meitinger T; Institute of Human Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Human Genetics, Technische Universität München, Neuherberg, Germany.; Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK), Partner Site Munich Heart Alliance, Munich, Germany., Tuomi T; Folkhälsan Research Center, Helsinki, Finland.; Department of Endocrinology, Helsinki University Central Hospital, Helsinki, Finland., Hakaste L; Folkhälsan Research Center, Helsinki, Finland., Kravic J; Diabetes and Endocrinology Unit, Department of Clinical Sciences Malmö, Lund University Diabetes Centre, Malmö, Sweden., Jørgensen ME; Steno Diabetes Center, Gentofte, Denmark., Lauritzen T; Section of General Practice, Department of Public Health, Aarhus University, Aarhus, Denmark., Deloukas P; Department of Human Genetics, Wellcome Trust Sanger Institute, Hinxton, U.K., Stirrups KE; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, U.K.; Department of Haematology, University of Cambridge, Cambridge, U.K., Owen KR; Oxford Centre for Diabetes, Endocrinology & Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, U.K.; Oxford NIHR Biomedical Research Centre, Oxford University Hospitals Trust, Oxford, U.K., Farmer AJ; Department of Primary Care Health Sciences, University of Oxford, Oxford, U.K., Frayling TM; Genetics of Complex Traits, University of Exeter Medical School, Exeter, U.K., O'Rahilly SP; Metabolic Research Laboratories, Institute of Metabolic Science, University of Cambridge, Cambridge, U.K., Walker M; Institute of Cellular Medicine, University of Newcastle, Newcastle, U.K., Levy JC; Oxford Centre for Diabetes, Endocrinology & Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, U.K., Hodgkiss D; Department of Twin Research & Genetic Epidemiology, King's College London, London, U.K., Hattersley AT; University of Exeter Medical School, Exeter, U.K., Kuulasmaa T; Internal Medicine, Institute of Clinical Medicine, Faculty of Health Sciences, University of Eastern Finland, Kuopio, Finland., Stančáková A; Internal Medicine, Institute of Clinical Medicine, Faculty of Health Sciences, University of Eastern Finland, Kuopio, Finland., Barroso I; Department of Human Genetics, Wellcome Trust Sanger Institute, Hinxton, U.K.; Metabolic Research Laboratories, Institute of Metabolic Science, University of Cambridge, Cambridge, U.K., Bharadwaj D; Functional Genomics Unit, CSIR-Institute of Genomics & Integrative Biology, New Delhi, India., Chan J; Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, China.; Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, China.; Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Hong Kong, China., Chandak GR; CSIR-Centre for Cellular & Molecular Biology, Hyderabad, India., Daly MJ; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA., Donnelly PJ; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, U.K.; Department of Statistics, University of Oxford, Oxford, U.K., Ebrahim SB; Centre for Chronic Disease Control, New Delhi, India., Elliott P; Department of Epidemiology and Biostatistics, Imperial College London, London, U.K.; MRC-PHE Centre for Environment & Health, Imperial College London, London, U.K., Fingerlin T; Department of Epidemiology, Colorado School of Public Health, University of Colorado, Aurora, CO., Froguel P; Genomics and Molecular Physiology, CNRS Institut de Biologie de Lille, Lille, France., Hu C; Department of Endocrinology and Metabolism, Shanghai Diabetes Institute, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China., Jia W; Department of Endocrinology and Metabolism, Shanghai Diabetes Institute, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China., Ma RCW; Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, China.; Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, China.; Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Hong Kong, China., McVean G; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, U.K., Park T; Interdisciplinary Program in Bioinformatics, Seoul National University, Seoul, Republic of Korea.; Department of Statistics, Seoul National University, Seoul, Republic of Korea., Prabhakaran D; Centre for Chronic Disease Control, New Delhi, India., Sandhu M; Department of Human Genetics, Wellcome Trust Sanger Institute, Hinxton, U.K.; Institute of Public Health, Department of Public Health and Primary Care, University of Cambridge, Cambridge, U.K., Scott J; Cardiovascular Sciences, National Heart and Lung Institute, Imperial College London, London, U.K., Sladek R; McGill University and Génome Québec Innovation Centre, Montreal, Canada.; Department of Human Genetics, McGill University, Montreal, Canada.; Division of Endocrinology and Metabolism, Department of Medicine, McGill University, Montreal, Canada., Tandon N; Department of Endocrinology and Metabolism, All India Institute of Medical Sciences, New Delhi, India., Teo YY; Saw Swee Hock School of Public Health, National University of Singapore, Singapore.; Life Sciences Institute, National University of Singapore, Singapore.; Department of Statistics and Applied Probability, National University of Singapore, Singapore., Zeggini E; Department of Human Genetics, Wellcome Trust Sanger Institute, Hinxton, U.K., Watanabe RM; Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA.; Department of Physiology and Biophysics, Keck School of Medicine, University of Southern California, Los Angeles, CA.; Diabetes & Obesity Research Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA., Koistinen HA; Department of Health, National Institute for Health and Welfare, Helsinki, Finland.; Department of Medicine and Abdominal Center, Endocrinology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland.; Minerva Foundation Institute for Medical Research, Helsinki, Finland., Kesaniemi YA; Institute of Clinical Medicine, Faculty of Medicine, University of Oulu, Oulu, Finland., Uusitupa M; Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland., Spector TD; Department of Twin Research & Genetic Epidemiology, King's College London, London, U.K., Salomaa V; Department of Health, National Institute for Health and Welfare, Helsinki, Finland., Rauramaa R; Foundation for Research in Health Exercise and Nutrition, Kuopio Research Institute of Exercise Medicine, Kuopio, Finland., Palmer CNA; Pat Macpherson Centre for Pharmacogenetics and Pharmacogenomics, Medical Research Institute, Ninewells Hospital and Medical School, Dundee, U.K., Prokopenko I; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, U.K.; Oxford Centre for Diabetes, Endocrinology & Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, U.K.; Department of Genomics of Common Disease, School of Public Health, Imperial College London, London, U.K., Morris AD; Division for Molecular Medicine, Clinical Research Centre, Ninewells Hospital and Medical School, Dundee, U.K., Bergman RN; Diabetes and Obesity Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA., Collins FS; National Human Genome Research Institute, National Institutes of Health, Bethesda, MD., Lind L; Department of Medical Sciences, Uppsala University, Uppsala, Sweden., Ingelsson E; Molecular Medicine and Science for Life Laboratory, Department of Medical Sciences, Uppsala University, Uppsala, Sweden.; Division of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, CA., Tuomilehto J; Diabetes Prevention Unit, National Institute for Health and Welfare, Helsinki, Finland.; Center for Vascular Prevention, Danube University Krems, Krems, Austria.; Diabetes Research Group, King Abdulaziz University, Jeddah, Saudi Arabia.; Dasman Diabetes Institute, Dasman, Kuwait., Karpe F; Oxford Centre for Diabetes, Endocrinology & Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, U.K.; Oxford NIHR Biomedical Research Centre, Oxford University Hospitals Trust, Oxford, U.K., Groop L; Diabetes and Endocrinology Unit, Department of Clinical Sciences Malmö, Lund University Diabetes Centre, Malmö, Sweden., Jørgensen T; Research Centre for Prevention and Health, Glostrup University Hospital, Glostrup, Denmark.; Faculty of Medicine, University of Aalborg, Aalborg, Denmark., Hansen T; The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Faculty of Health Sciences, University of Southern Denmark, Odense, Denmark., Pedersen O; The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Kuusisto J; Internal Medicine, Institute of Clinical Medicine, Faculty of Health Sciences, University of Eastern Finland, Kuopio, Finland.; Kuopio University Hospital, Kuopio, Finland., Abecasis G; Department of Biostatistics and Center for Statistical Genetics, School of Public Health, University of Michigan, Ann Arbor, MI., Bell GI; Departments of Medicine and Human Genetics, The University of Chicago, Chicago, IL., Blangero J; Department of Genetics, Texas Biomedical Research Institute, San Antonio, TX., Cox NJ; Section of Genetic Medicine, Department of Medicine, The University of Chicago, Chicago, IL., Duggirala R; Department of Genetics, Texas Biomedical Research Institute, San Antonio, TX., Seielstad M; Department of Laboratory Medicine, Institute for Human Genetics, University of California, San Francisco, San Francisco, CA.; Blood Systems Research Institute, San Francisco, CA., Wilson JG; Department of Physiology and Biophysics, University of Mississippi Medical Center, Jackson, MS., Dupuis J; Department of Biostatistics, Boston University School of Public Health, Boston, MA.; Framingham Heart Study, National Heart, Lung, and Blood Institute, Framingham, MA., Ripatti S; Wellcome Trust Sanger Institute, Hinxton, U.K.; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland.; Hjelt Institute, University of Helsinki, Helsinki, Finland., Hanis CL; Human Genetics Center, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX., Florez JC; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA.; Center for Human Genetic Research, Department of Medicine, Massachusetts General Hospital, Boston, MA.; Department of Medicine, Harvard Medical School, Boston, MA.; Diabetes Research Center (Diabetes Unit), Department of Medicine, Massachusetts General Hospital, Boston, MA., Mohlke KL; Department of Genetics, The University of North Carolina at Chapel Hill, Chapel Hill, NC., Meigs JB; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA.; Department of Medicine, Harvard Medical School, Boston, MA.; Division of General Internal Medicine, Massachusetts General Hospital, Boston, MA., Laakso M; Internal Medicine, Institute of Clinical Medicine, Faculty of Health Sciences, University of Eastern Finland, Kuopio, Finland.; Kuopio University Hospital, Kuopio, Finland., Morris AP; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, U.K.; Estonian Genome Center, University of Tartu, Tartu, Estonia.; Department of Biostatistics, University of Liverpool, Liverpool, U.K., Boehnke M; Department of Biostatistics and Center for Statistical Genetics, School of Public Health, University of Michigan, Ann Arbor, MI., Altshuler D; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA.; Department of Medicine, Harvard Medical School, Boston, MA.; Department of Genetics, Harvard Medical School, Boston, MA.; Department of Molecular Biology, Massachusetts General Hospital, Boston, MA.; Diabetes Research Center (Diabetes Unit), Department of Medicine, Massachusetts General Hospital, Boston, MA.; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA., McCarthy MI; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, U.K.; Oxford Centre for Diabetes, Endocrinology & Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, U.K.; Oxford NIHR Biomedical Research Centre, Oxford University Hospitals Trust, Oxford, U.K., Gloyn AL; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, U.K.; Oxford Centre for Diabetes, Endocrinology & Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, U.K.; Oxford NIHR Biomedical Research Centre, Oxford University Hospitals Trust, Oxford, U.K., Lindgren CM; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA.; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, U.K.; Big Data Institute, Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford, U.K.
Publikováno v:
Diabetes [Diabetes] 2017 Jul; Vol. 66 (7), pp. 2019-2032. Date of Electronic Publication: 2017 Mar 24.
Autor:
Liu F; Department of Forensic Molecular Biology, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands, f.liu@erasmusmc.nl., Visser M, Duffy DL, Hysi PG, Jacobs LC, Lao O, Zhong K, Walsh S, Chaitanya L, Wollstein A, Zhu G, Montgomery GW, Henders AK, Mangino M, Glass D, Bataille V, Sturm RA, Rivadeneira F, Hofman A, van IJcken WF, Uitterlinden AG, Palstra RJ, Spector TD, Martin NG, Nijsten TE, Kayser M
Publikováno v:
Human genetics [Hum Genet] 2015 Aug; Vol. 134 (8), pp. 823-35. Date of Electronic Publication: 2015 May 12.
Autor:
Wood AR; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, UK., Esko T; 1] Estonian Genome Center, University of Tartu, Tartu, Estonia. [2] Division of Endocrinology, Genetics and Basic and Translational Obesity Research, Boston Children's Hospital, Boston, Massachusetts, USA. [3] Broad Institute of MIT and Harvard University, Cambridge, Massachusetts, USA. [4] Department of Genetics, Harvard Medical School, Boston, Massachusetts, USA., Yang J; 1] Queensland Brain Institute, University of Queensland, Brisbane, Queensland, Australia. [2] University of Queensland Diamantina Institute, Translation Research Institute, Brisbane, Queensland, Australia., Vedantam S; 1] Division of Endocrinology, Genetics and Basic and Translational Obesity Research, Boston Children's Hospital, Boston, Massachusetts, USA. [2] Broad Institute of MIT and Harvard University, Cambridge, Massachusetts, USA., Pers TH; 1] Division of Endocrinology, Genetics and Basic and Translational Obesity Research, Boston Children's Hospital, Boston, Massachusetts, USA. [2] Broad Institute of MIT and Harvard University, Cambridge, Massachusetts, USA. [3] Department of Genetics, Harvard Medical School, Boston, Massachusetts, USA. [4] Center for Biological Sequence Analysis, Department of Systems Biology, Technical University of Denmark, Lyngby, Denmark., Gustafsson S; 1] Science for Life Laboratory, Uppsala University, Uppsala, Sweden. [2] Department of Medical Sciences, Molecular Epidemiology, Uppsala University, Uppsala, Sweden., Chu AY; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA., Estrada K; 1] Broad Institute of MIT and Harvard University, Cambridge, Massachusetts, USA. [2] Department of Internal Medicine, Erasmus Medical Center, Rotterdam, the Netherlands. [3] Analytic and Translational Genetics Unit, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA., Luan J; Medical Research Council (MRC) Epidemiology Unit, University of Cambridge, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK., Kutalik Z; 1] Institute of Social and Preventive Medicine (IUMSP), Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland. [2] Swiss Institute of Bioinformatics, Lausanne, Switzerland. [3] Department of Medical Genetics, University of Lausanne, Lausanne, Switzerland., Amin N; Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands., Buchkovich ML; Department of Genetics, University of North Carolina, Chapel Hill, North Carolina, USA., Croteau-Chonka DC; 1] Department of Genetics, University of North Carolina, Chapel Hill, North Carolina, USA. [2] Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA., Day FR; Medical Research Council (MRC) Epidemiology Unit, University of Cambridge, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK., Duan Y; Department of Genetics, Division of Statistical Genomics, Washington University School of Medicine, St. Louis, Missouri, USA., Fall T; 1] Science for Life Laboratory, Uppsala University, Uppsala, Sweden. [2] Department of Medical Sciences, Molecular Epidemiology, Uppsala University, Uppsala, Sweden. [3] Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Fehrmann R; Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Ferreira T; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK., Jackson AU; Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA., Karjalainen J; Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Lo KS; Montreal Heart Institute, Montreal, Quebec, Canada., Locke AE; Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA., Mägi R; 1] Estonian Genome Center, University of Tartu, Tartu, Estonia. [2] Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK., Mihailov E; 1] Estonian Genome Center, University of Tartu, Tartu, Estonia. [2] Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia., Porcu E; Istituto di Ricerca Genetica e Biomedica (IRGB), Consiglio Nazionale delle Ricerche, Cagliari, Italy., Randall JC; 1] Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK. [2] Wellcome Trust Sanger Institute, Hinxton, UK., Scherag A; 1] Institute for Medical Informatics, Biometry and Epidemiology (IMIBE), University Hospital Essen, Essen, Germany. [2] Clinical Epidemiology, Integrated Research and Treatment Center, Center for Sepsis Control and Care (CSCC), Jena University Hospital, Jena, Germany., Vinkhuyzen AA; Queensland Brain Institute, University of Queensland, Brisbane, Queensland, Australia., Westra HJ; Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Winkler TW; Department of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University of Regensburg, Regensburg, Germany., Workalemahu T; Department of Nutrition, Harvard School of Public Health, Harvard University, Boston, Massachusetts, USA., Zhao JH; Medical Research Council (MRC) Epidemiology Unit, University of Cambridge, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK., Absher D; HudsonAlpha Institute for Biotechnology, Huntsville, Alabama, USA., Albrecht E; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany., Anderson D; Telethon Institute for Child Health Research, Centre for Child Health Research, University of Western Australia, Perth, Western Australia, Australia., Baron J; Section on Growth and Development, Program in Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, US National Institutes of Health, Bethesda, Maryland, USA., Beekman M; 1] Netherlands Consortium for Healthy Aging (NCHA), Leiden University Medical Center, Leiden, the Netherlands. [2] Department of Molecular Epidemiology, Leiden University Medical Center, Leiden, the Netherlands., Demirkan A; 1] Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands. [2] Department of Human Genetics, Leiden University Medical Center, Leiden, the Netherlands., Ehret GB; 1] Center for Complex Disease Genomics, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA. [2] Department of Specialties of Internal Medicine, Division of Cardiology, Geneva University Hospital, Geneva, Switzerland., Feenstra B; Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark., Feitosa MF; Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, USA., Fischer K; Estonian Genome Center, University of Tartu, Tartu, Estonia., Fraser RM; Centre for Population Health Sciences, University of Edinburgh, Edinburgh, UK., Goel A; 1] Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK. [2] Radcliffe Department of Medicine, Division of Cardiovascular Medicine, University of Oxford, Oxford, UK., Gong J; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA., Justice AE; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Kanoni S; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Kleber ME; 1] Vth Department of Medicine (Nephrology, Hypertensiology, Endocrinology, Diabetology, Rheumatology), Medical Faculty of Mannheim, University of Heidelberg, Heidelberg, Germany. [2] Department of Internal Medicine II, Ulm University Medical Centre, Ulm, Germany., Kristiansson K; National Institute for Health and Welfare, Helsinki, Finland., Lim U; Epidemiology Program, University of Hawaii Cancer Center, Honolulu, Hawaii, USA., Lotay V; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Lui JC; Section on Growth and Development, Program in Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, US National Institutes of Health, Bethesda, Maryland, USA., Mangino M; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., Mateo Leach I; Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Medina-Gomez C; 1] Department of Internal Medicine, Erasmus Medical Center, Rotterdam, the Netherlands. [2] Netherlands Consortium for Healthy Aging (NCHA), Rotterdam, the Netherlands. [3] Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands., Nalls MA; Laboratory of Neurogenetics, National Institute on Aging, US National Institutes of Health, Bethesda, Maryland, USA., Nyholt DR; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Palmer CD; 1] Division of Endocrinology, Genetics and Basic and Translational Obesity Research, Boston Children's Hospital, Boston, Massachusetts, USA. [2] Broad Institute of MIT and Harvard University, Cambridge, Massachusetts, USA., Pasko D; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, UK., Pechlivanis S; Institute for Medical Informatics, Biometry and Epidemiology (IMIBE), University Hospital Essen, Essen, Germany., Prokopenko I; 1] Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK. [2] Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK. [3] Department of Genomics of Common Disease, School of Public Health, Imperial College London, Hammersmith Hospital, London, UK., Ried JS; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany., Ripke S; 1] Analytic and Translational Genetics Unit, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA. [2] Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard University, Cambridge, Massachusetts, USA., Shungin D; 1] Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University Diabetes Center, Skåne University Hospital, Malmö, Sweden. [2] Department of Public Health and Clinical Medicine, Unit of Medicine, Umeå University, Umeå, Sweden. [3] Department of Odontology, Umeå University, Umeå, Sweden., Stancáková A; Department of Medicine, University of Eastern Finland, Kuopio, Finland., Strawbridge RJ; Atherosclerosis Research Unit, Center for Molecular Medicine, Department of Medicine, Karolinska Institutet, Stockholm, Sweden., Sung YJ; Division of Biostatistics, Washington University School of Medicine, St. Louis, Missouri, USA., Tanaka T; Translational Gerontology Branch, National Institute on Aging, Baltimore, Maryland, USA., Teumer A; Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany., Trompet S; 1] Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands. [2] Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, the Netherlands., van der Laan SW; Experimental Cardiology Laboratory, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands., van Setten J; Department of Medical Genetics, University Medical Center Utrecht, Utrecht, the Netherlands., Van Vliet-Ostaptchouk JV; Department of Endocrinology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Wang Z; 1] DZHK (Deutsches Zentrum für Herz-Kreislaufforschung-German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, Germany. [2] Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald, Germany. [3] Division of Cancer Epidemiology and Genetics, National Cancer Institute, US National Institutes of Health, Bethesda, Maryland, USA. [4] Core Genotyping Facility, SAIC-Frederick, Inc., NCI-Frederick, Frederick, Maryland, USA., Yengo L; 1] CNRS UMR 8199, Lille, France. [2] European Genomic Institute for Diabetes, Lille, France. [3] Université de Lille 2, Lille, France., Zhang W; 1] Ealing Hospital National Health Service (NHS) Trust, Middlesex, UK. [2] Department of Epidemiology and Biostatistics, Imperial College London, London, UK., Afzal U; 1] Ealing Hospital National Health Service (NHS) Trust, Middlesex, UK. [2] Department of Epidemiology and Biostatistics, Imperial College London, London, UK., Arnlöv J; 1] Science for Life Laboratory, Uppsala University, Uppsala, Sweden. [2] Department of Medical Sciences, Molecular Epidemiology, Uppsala University, Uppsala, Sweden. [3] School of Health and Social Studies, Dalarna University, Falun, Sweden., Arscott GM; PathWest Laboratory Medicine of Western Australia, Nedlands, Western Australia, Australia., Bandinelli S; Geriatric Unit, Azienda Sanitaria Firenze (ASF), Florence, Italy., Barrett A; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK., Bellis C; Department of Genetics, Texas Biomedical Research Institute, San Antonio, Texas, USA., Bennett AJ; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK., Berne C; Department of Medical Sciences, Endocrinology, Diabetes and Metabolism, Uppsala University, Uppsala, Sweden., Blüher M; 1] Integrated Research and Treatment Center (IFB) Adiposity Diseases, University of Leipzig, Leipzig, Germany. [2] Department of Medicine, University of Leipzig, Leipzig, Germany., Bolton JL; Centre for Population Health Sciences, University of Edinburgh, Edinburgh, UK., Böttcher Y; Integrated Research and Treatment Center (IFB) Adiposity Diseases, University of Leipzig, Leipzig, Germany., Boyd HA; Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark., Bruinenberg M; LifeLines, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Buckley BM; Department of Pharmacology and Therapeutics, University College Cork, Cork, Ireland., Buyske S; 1] Department of Statistics and Biostatistics, Rutgers University, Piscataway, New Jersy, USA. [2] Department of Genetics, Rutgers University, Piscataway, New Jersey, USA., Caspersen IH; Department of Biology, Norwegian University of Science and Technology, Trondheim, Norway., Chines PS; Genome Technology Branch, National Human Genome Research Institute, US National Institutes of Health, Bethesda, Maryland, USA., Clarke R; Clinical Trial Service Unit, Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK., Claudi-Boehm S; Division of Endocrinology, Diabetes and Metabolism, Ulm University Medical Centre, Ulm, Germany., Cooper M; Telethon Institute for Child Health Research, Centre for Child Health Research, University of Western Australia, Perth, Western Australia, Australia., Daw EW; Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, USA., De Jong PA; Department of Radiology, University Medical Center Utrecht, Utrecht, the Netherlands., Deelen J; 1] Netherlands Consortium for Healthy Aging (NCHA), Leiden University Medical Center, Leiden, the Netherlands. [2] Department of Molecular Epidemiology, Leiden University Medical Center, Leiden, the Netherlands., Delgado G; Vth Department of Medicine (Nephrology, Hypertensiology, Endocrinology, Diabetology, Rheumatology), Medical Faculty of Mannheim, University of Heidelberg, Heidelberg, Germany., Denny JC; Department of Biomedical Informatics, Vanderbilt University, Nashville, Tennessee, USA., Dhonukshe-Rutten R; Department of Human Nutrition, Wageningen University, Wageningen, the Netherlands., Dimitriou M; Department of Dietetics-Nutrition, Harokopio University, Athens, Greece., Doney AS; Medical Research Institute, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK., Dörr M; 1] DZHK (Deutsches Zentrum für Herz-Kreislaufforschung-German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, Germany. [2] Department of Internal Medicine B, University Medicine Greifswald, Greifswald, Germany., Eklund N; 1] National Institute for Health and Welfare, Helsinki, Finland. [2] Institute for Molecular Medicine, University of Helsinki, Helsinki, Finland., Eury E; 1] CNRS UMR 8199, Lille, France. [2] European Genomic Institute for Diabetes, Lille, France. [3] Université de Lille 2, Lille, France., Folkersen L; Atherosclerosis Research Unit, Center for Molecular Medicine, Department of Medicine, Karolinska Institutet, Stockholm, Sweden., Garcia ME; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, US National Institutes of Health, Bethesda, Maryland, USA., Geller F; Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark., Giedraitis V; Department of Public Health and Caring Sciences, Geriatrics, Uppsala University, Uppsala, Sweden., Go AS; Kaiser Permanente, Division of Research, Oakland, California, USA., Grallert H; 1] Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany. [2] Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany. [3] German Center for Diabetes Research (DZD), Neuherberg, Germany., Grammer TB; Vth Department of Medicine (Nephrology, Hypertensiology, Endocrinology, Diabetology, Rheumatology), Medical Faculty of Mannheim, University of Heidelberg, Heidelberg, Germany., Gräßler J; Department of Medicine III, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany., Grönberg H; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., de Groot LC; Department of Human Nutrition, Wageningen University, Wageningen, the Netherlands., Groves CJ; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK., Haessler J; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA., Hall P; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Haller T; Estonian Genome Center, University of Tartu, Tartu, Estonia., Hallmans G; Unit of Nutritional Research, Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden., Hannemann A; Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald, Germany., Hartman CA; Department of Psychiatry, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Hassinen M; Kuopio Research Institute of Exercise Medicine, Kuopio, Finland., Hayward C; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, UK., Heard-Costa NL; 1] National Heart, Lung, and Blood Institute, Framingham Heart Study, Framingham, Massachusetts, USA. [2] Department of Neurology, Boston University School of Medicine, Boston, Massachusetts, USA., Helmer Q; 1] Netherlands Consortium for Healthy Aging (NCHA), Leiden University Medical Center, Leiden, the Netherlands. [2] Department of Medical Statistics and Bioinformatics, Leiden University Medical Center, Leiden, the Netherlands. [3] Faculty of Psychology and Education, VU University Amsterdam, Amsterdam, the Netherlands., Hemani G; 1] Queensland Brain Institute, University of Queensland, Brisbane, Queensland, Australia. [2] University of Queensland Diamantina Institute, Translation Research Institute, Brisbane, Queensland, Australia., Henders AK; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Hillege HL; 1] Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands. [2] Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Hlatky MA; Department of Medicine, Stanford University School of Medicine, Stanford, California, USA., Hoffmann W; 1] DZHK (Deutsches Zentrum für Herz-Kreislaufforschung-German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, Germany. [2] Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany., Hoffmann P; 1] Department of Biomedicine, Division of Medical Genetics, University of Basel, Basel, Switzerland. [2] Department of Genomics, Life and Brain Center, University of Bonn, Bonn, Germany. [3] Institute of Human Genetics, University of Bonn, Bonn, Germany., Holmen O; Department of Public Health and General Practice, Norwegian University of Science and Technology, Trondheim, Norway., Houwing-Duistermaat JJ; 1] Netherlands Consortium for Healthy Aging (NCHA), Leiden University Medical Center, Leiden, the Netherlands. [2] Department of Medical Statistics and Bioinformatics, Leiden University Medical Center, Leiden, the Netherlands., Illig T; 1] Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany. [2] Hannover Unified Biobank, Hannover Medical School, Hannover, Germany., Isaacs A; 1] Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands. [2] Center for Medical Systems Biology, Leiden, the Netherlands., James AL; 1] Department of Pulmonary Physiology and Sleep Medicine, Nedlands, Western Australia, Australia. [2] School of Medicine and Pharmacology, University of Western Australia, Crawley, Western Australia, Australia., Jeff J; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Johansen B; Department of Biology, Norwegian University of Science and Technology, Trondheim, Norway., Johansson Å; Department of Immunology, Genetics and Pathology, SciLifeLab, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden., Jolley J; 1] Department of Haematology, University of Cambridge, Cambridge, UK. [2] NHS Blood and Transplant, Cambridge, UK., Juliusdottir T; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK., Junttila J; Department of Medicine, University of Oulu, Oulu, Finland., Kho AN; Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA., Kinnunen L; National Institute for Health and Welfare, Helsinki, Finland., Klopp N; 1] Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany. [2] Hannover Unified Biobank, Hannover Medical School, Hannover, Germany., Kocher T; Unit of Periodontology, Department of Restorative Dentistry, Periodontology and Endodontology, University Medicine Greifswald, Greifswald, Germany., Kratzer W; Department of Internal Medicine I, Ulm University Medical Centre, Ulm, Germany., Lichtner P; Institute of Human Genetics, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany., Lind L; Department of Medical Sciences, Cardiovascular Epidemiology, Uppsala University, Uppsala, Sweden., Lindström J; National Institute for Health and Welfare, Helsinki, Finland., Lobbens S; 1] CNRS UMR 8199, Lille, France. [2] European Genomic Institute for Diabetes, Lille, France. [3] Université de Lille 2, Lille, France., Lorentzon M; Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden., Lu Y; 1] Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA. [2] Genetics of Obesity and Related Metabolic Traits Program, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Lyssenko V; Steno Diabetes Center A/S, Gentofte Denmark., Magnusson PK; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Mahajan A; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK., Maillard M; Service of Nephrology, Department of Medicine, Lausanne University Hospital (CHUV), Lausanne, Switzerland., McArdle WL; School of Social and Community Medicine, University of Bristol, Bristol, UK., McKenzie CA; Tropical Metabolism Research Unit, Tropical Medicine Research Institute, University of the West Indies, Mona, Kingston, Jamaica., McLachlan S; Centre for Population Health Sciences, University of Edinburgh, Edinburgh, UK., McLaren PJ; 1] Global Health Institute, Department of Life Sciences, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland. [2] Institute of Microbiology, University Hospital and University of Lausanne, Lausanne, Switzerland., Menni C; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., Merger S; Division of Endocrinology, Diabetes and Metabolism, Ulm University Medical Centre, Ulm, Germany., Milani L; Estonian Genome Center, University of Tartu, Tartu, Estonia., Moayyeri A; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., Monda KL; 1] Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA. [2] Center for Observational Research, Amgen, Inc., Thousand Oaks, California, USA., Morken MA; Genome Technology Branch, National Human Genome Research Institute, US National Institutes of Health, Bethesda, Maryland, USA., Müller G; Center for Evidence-Based Healthcare, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany., Müller-Nurasyid M; 1] Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany. [2] Department of Medicine I, University Hospital Großhadern, Ludwig Maximilians Universität, Munich, Germany. [3] Chair of Genetic Epidemiology, Institute of Medical Informatics, Biometry and Epidemiology, Ludwig Maximilians Universität, Neuherberg, Germany. [4] DZHK (Deutsches Forschungszentrum für Herz-Kreislauferkrankungen-German Research Centre for Cardiovascular Research), Munich Heart Alliance, Munich, Germany., Musk AW; Department of Respiratory Medicine, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia., Narisu N; Genome Technology Branch, National Human Genome Research Institute, US National Institutes of Health, Bethesda, Maryland, USA., Nauck M; 1] DZHK (Deutsches Zentrum für Herz-Kreislaufforschung-German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, Germany. [2] Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald, Germany., Nolte IM; Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Nöthen MM; 1] Department of Genomics, Life and Brain Center, University of Bonn, Bonn, Germany. [2] Institute of Human Genetics, University of Bonn, Bonn, Germany., Oozageer L; Ealing Hospital National Health Service (NHS) Trust, Middlesex, UK., Pilz S; 1] Department of Epidemiology and Biostatistics, Institute for Research in Extramural Medicine (EMGO) Institute for Health and Care Research, VU University Medical Center, Amsterdam, the Netherlands. [2] Department of Internal Medicine, Division of Endocrinology and Metabolism, Medical University of Graz, Graz, Austria., Rayner NW; 1] Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK. [2] Wellcome Trust Sanger Institute, Hinxton, UK. [3] Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK., Renstrom F; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University Diabetes Center, Skåne University Hospital, Malmö, Sweden., Robertson NR; 1] Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK. [2] Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK., Rose LM; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA., Roussel R; 1] Diabetology-Endocrinology-Nutrition, Public Hospital System of the City of Paris (AP-HP), Bichat Hospital, Paris, France. [2] INSERM U872, Centre de Recherche des Cordeliers, Paris, France. [3] Paris Diderot University, Paris, France., Sanna S; Istituto di Ricerca Genetica e Biomedica (IRGB), Consiglio Nazionale delle Ricerche, Cagliari, Italy., Scharnagl H; Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz, Austria., Scholtens S; Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Schumacher FR; Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA., Schunkert H; 1] DZHK (Deutsches Forschungszentrum für Herz-Kreislauferkrankungen-German Research Centre for Cardiovascular Research), Munich Heart Alliance, Munich, Germany. [2] Deutsches Herzzentrum München, Technische Universität München, Munich, Germany., Scott RA; Medical Research Council (MRC) Epidemiology Unit, University of Cambridge, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK., Sehmi J; 1] Ealing Hospital National Health Service (NHS) Trust, Middlesex, UK. [2] Department of Epidemiology and Biostatistics, Imperial College London, London, UK., Seufferlein T; Department of Internal Medicine I, Ulm University Medical Centre, Ulm, Germany., Shi J; National Cancer Institute, Bethesda, Maryland, USA., Silventoinen K; Department of Sociology, University of Helsinki, Helsinki, Finland., Smit JH; 1] EMGO Institute for Health and Care Research, VU University, Amsterdam, the Netherlands. [2] Department of Psychiatry, Neuroscience Campus, VU University Amsterdam, Amsterdam, the Netherlands., Smith AV; 1] Icelandic Heart Association, Kopavogur, Iceland. [2] University of Iceland, Reykjavik, Iceland., Smolonska J; 1] Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands. [2] Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Stanton AV; Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland, Dublin, Ireland., Stirrups K; 1] Wellcome Trust Sanger Institute, Hinxton, UK. [2] William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Stott DJ; Institute of Cardiovascular and Medical Sciences, Faculty of Medicine, University of Glasgow, Glasgow, UK., Stringham HM; Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA., Sundström J; Department of Medical Sciences, Cardiovascular Epidemiology, Uppsala University, Uppsala, Sweden., Swertz MA; Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Syvänen AC; 1] Science for Life Laboratory, Uppsala University, Uppsala, Sweden. [2] Department of Medical Sciences, Molecular Medicine, Uppsala University, Uppsala, Sweden., Tayo BO; Department of Public Health Sciences, Stritch School of Medicine, Loyola University of Chicago, Maywood, Illinois, USA., Thorleifsson G; deCODE Genetics, Amgen, Inc., Reykjavik, Iceland., Tyrer JP; Department of Oncology, University of Cambridge, Cambridge, UK., van Dijk S; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, the Netherlands., van Schoor NM; Department of Epidemiology and Biostatistics, Institute for Research in Extramural Medicine (EMGO) Institute for Health and Care Research, VU University Medical Center, Amsterdam, the Netherlands., van der Velde N; 1] Department of Internal Medicine, Erasmus Medical Center, Rotterdam, the Netherlands. [2] Section of Geriatrics, Department of Internal Medicine, Academic Medical Center, Amsterdam, the Netherlands., van Heemst D; 1] Netherlands Consortium for Healthy Aging (NCHA), Leiden University Medical Center, Leiden, the Netherlands. [2] Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, the Netherlands., van Oort FV; Department of Child and Adolescent Psychiatry, Psychology, Erasmus University Medical Center, Rotterdam, the Netherlands., Vermeulen SH; 1] Department for Health Evidence, Radboud University Medical Centre, Nijmegen, the Netherlands. [2] Department of Genetics, Radboud University Medical Centre, Nijmegen, the Netherlands., Verweij N; Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Vonk JM; Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Waite LL; HudsonAlpha Institute for Biotechnology, Huntsville, Alabama, USA., Waldenberger M; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany., Wennauer R; Department of Clinical Chemistry, Ulm University Medical Centre, Ulm, Germany., Wilkens LR; Epidemiology Program, University of Hawaii Cancer Center, Honolulu, Hawaii, USA., Willenborg C; 1] DZHK (Deutsches Forschungszentrum für Herz-Kreislauferkrankungen-German Research Centre for Cardiovascular Research), partner site Hamburg-Lubeck-Kiel, Lubeck, Germany. [2] Institut für Integrative und Experimentelle Genomik, Universität zu Lübeck, Lübeck, Germany., Wilsgaard T; Department of Community Medicine, Faculty of Health Sciences, UiT The Arctic University of Tromsø, Tromsø, Norway., Wojczynski MK; Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, USA., Wong A; MRC Unit for Lifelong Health and Ageing at University College London, London, UK., Wright AF; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, UK., Zhang Q; Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, USA., Arveiler D; Department of Epidemiology and Public Health, University of Strasbourg, Faculty of Medicine, Strasbourg, France., Bakker SJ; Department of Internal Medicine, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Beilby J; 1] PathWest Laboratory Medicine of Western Australia, Nedlands, Western Australia, Australia. [2] Pathology and Laboratory Medicine, University of Western Australia, Perth, Western Australia, Australia., Bergman RN; Cedars-Sinai Diabetes and Obesity Research Institute, Los Angeles, California, USA., Bergmann S; 1] Swiss Institute of Bioinformatics, Lausanne, Switzerland. [2] Department of Medical Genetics, University of Lausanne, Lausanne, Switzerland., Biffar R; Department of Prosthetic Dentistry, Gerostomatology and Dental Materials, University Medicine Greifswald, Greifswald, Germany., Blangero J; Department of Genetics, Texas Biomedical Research Institute, San Antonio, Texas, USA., Boomsma DI; Biological Psychology, VU University Amsterdam, Amsterdam, the Netherlands., Bornstein SR; Department of Medicine III, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany., Bovet P; 1] Institute of Social and Preventive Medicine (IUMSP), Centre Hospitalier Universitaire Vaudois (CHUV) and University of Lausanne, Lausanne, Switzerland. [2] Ministry of Health, Victoria, Republic of Seychelles., Brambilla P; Laboratory Medicine, Hospital of Desio, Department of Health Sciences, University of Milano, Bicocca, Italy., Brown MJ; Clinical Pharmacology Unit, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK., Campbell H; Centre for Population Health Sciences, University of Edinburgh, Edinburgh, UK., Caulfield MJ; 1] Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK. [2] Barts and The London Genome Centre, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Chakravarti A; Center for Complex Disease Genomics, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Collins R; Clinical Trial Service Unit, Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK., Collins FS; Genome Technology Branch, National Human Genome Research Institute, US National Institutes of Health, Bethesda, Maryland, USA., Crawford DC; 1] Center for Human Genetics Research, Vanderbilt University Medical Center, Nashville, Tennessee, USA. [2] Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, Tennessee, USA., Cupples LA; 1] National Heart, Lung, and Blood Institute, Framingham Heart Study, Framingham, Massachusetts, USA. [2] Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA., Danesh J; Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., de Faire U; Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden., den Ruijter HM; 1] Experimental Cardiology Laboratory, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands. [2] Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, the Netherlands., Erbel R; Clinic of Cardiology, West German Heart Centre, University Hospital Essen, Essen, Germany., Erdmann J; 1] DZHK (Deutsches Forschungszentrum für Herz-Kreislauferkrankungen-German Research Centre for Cardiovascular Research), partner site Hamburg-Lubeck-Kiel, Lubeck, Germany. [2] Institut für Integrative und Experimentelle Genomik, Universität zu Lübeck, Lübeck, Germany., Eriksson JG; 1] National Institute for Health and Welfare, Helsinki, Finland. [2] Department of General Practice and Primary Health Care, University of Helsinki, Helsinki, Finland. [3] Unit of General Practice, Helsinki University Central Hospital, Helsinki, Finland., Farrall M; 1] Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK. [2] Radcliffe Department of Medicine, Division of Cardiovascular Medicine, University of Oxford, Oxford, UK., Ferrannini E; 1] Department of Internal Medicine, University of Pisa, Pisa, Italy. [2] National Research Council (CNR) Institute of Clinical Physiology, University of Pisa, Pisa, Italy., Ferrières J; Department of Cardiology, Toulouse University School of Medicine, Rangueil Hospital, Toulouse, France., Ford I; Robertson Center for Biostatistics, University of Glasgow, Glasgow, UK., Forouhi NG; Medical Research Council (MRC) Epidemiology Unit, University of Cambridge, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK., Forrester T; Tropical Metabolism Research Unit, Tropical Medicine Research Institute, University of the West Indies, Mona, Kingston, Jamaica., Gansevoort RT; Department of Internal Medicine, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Gejman PV; NorthShore University HealthSystem, University of Chicago, Evanston, Illinois, USA., Gieger C; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany., Golay A; Service of Therapeutic Education for Diabetes, Obesity and Chronic Diseases, Geneva University Hospital, Geneva, Switzerland., Gottesman O; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Gudnason V; 1] Icelandic Heart Association, Kopavogur, Iceland. [2] University of Iceland, Reykjavik, Iceland., Gyllensten U; Department of Immunology, Genetics and Pathology, SciLifeLab, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden., Haas DW; Department of Medicine, Pharmacology, Pathology, Microbiology and Immunology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA., Hall AS; Leeds MRC Medical Bioinformatics Centre, University of Leeds, Leeds, UK., Harris TB; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, US National Institutes of Health, Bethesda, Maryland, USA., Hattersley AT; Institute of Biomedical and Clinical Science, University of Exeter, Exeter, UK., Heath AC; Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA., Hengstenberg C; 1] DZHK (Deutsches Forschungszentrum für Herz-Kreislauferkrankungen-German Research Centre for Cardiovascular Research), Munich Heart Alliance, Munich, Germany. [2] Deutsches Herzzentrum München, Technische Universität München, Munich, Germany., Hicks AA; Center for Biomedicine, European Academy Bozen, Bolzano (EURAC), Bolzano, Italy (affiliated institute of the University of Lübeck, Lübeck, Germany)., Hindorff LA; Division of Genomic Medicine, National Human Genome Research Institute, US National Institutes of Health, Bethesda, Maryland, USA., Hingorani AD; Institute of Cardiovascular Science, University College London, London, UK., Hofman A; 1] Netherlands Consortium for Healthy Aging (NCHA), Rotterdam, the Netherlands. [2] Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands., Hovingh GK; Department of Vascular Medicine, Academic Medical Center, Amsterdam, the Netherlands., Humphries SE; Centre for Cardiovascular Genetics, Institute of Cardiovascular Sciences, University College London, London, UK., Hunt SC; Cardiovascular Genetics Division, Department of Internal Medicine, University of Utah, Salt Lake City, Utah, USA., Hypponen E; 1] School of Population Health, University of South Australia, Adelaide, South Australia, Australia. [2] Sansom Institute for Health Research, University of South Australia, Adelaide, South Australia, Australia. [3] South Australian Health and Medical Research Institute, Adelaide, South Australia, Australia. [4] Centre for Paediatric Epidemiology and Biostatistics, University College London Institute of Child Health, London, UK., Jacobs KB; 1] Division of Cancer Epidemiology and Genetics, National Cancer Institute, US National Institutes of Health, Bethesda, Maryland, USA. [2] Core Genotyping Facility, SAIC-Frederick, Inc., NCI-Frederick, Frederick, Maryland, USA., Jarvelin MR; 1] Department of Epidemiology and Biostatistics, Imperial College London, London, UK. [2] National Institute for Health and Welfare, Oulu, Finland. [3] MRC Health Protection Agency (HPA) Centre for Environment and Health, School of Public Health, Imperial College London, London, UK. [4] Unit of Primary Care, Oulu University Hospital, Oulu, Finland. [5] Biocenter Oulu, University of Oulu, Oulu, Finland. [6] Institute of Health Sciences, University of Oulu, Oulu, Finland., Jousilahti P; National Institute for Health and Welfare, Helsinki, Finland., Jula AM; National Institute for Health and Welfare, Helsinki, Finland., Kaprio J; 1] National Institute for Health and Welfare, Helsinki, Finland. [2] Institute for Molecular Medicine, University of Helsinki, Helsinki, Finland. [3] Hjelt Institute Department of Public Health, University of Helsinki, Helsinki, Finland., Kastelein JJ; Department of Vascular Medicine, Academic Medical Center, Amsterdam, the Netherlands., Kayser M; 1] Netherlands Consortium for Healthy Aging (NCHA), Rotterdam, the Netherlands. [2] Department of Forensic Molecular Biology, Erasmus Medical Center, Rotterdam, the Netherlands., Kee F; UK Clinical Research Collaboration Centre of Excellence for Public Health (Northern Ireland), Queens University of Belfast, Belfast, UK., Keinanen-Kiukaanniemi SM; 1] Faculty of Medicine, Institute of Health Sciences, University of Oulu, Oulu, Finland. [2] Unit of General Practice, Oulu University Hospital, Oulu, Finland., Kiemeney LA; 1] Department for Health Evidence, Radboud University Medical Centre, Nijmegen, the Netherlands. [2] Department of Urology, Radboud University Medical Centre, Nijmegen, the Netherlands., Kooner JS; 1] Ealing Hospital National Health Service (NHS) Trust, Middlesex, UK. [2] Imperial College Healthcare NHS Trust, London, UK. [3] National Heart and Lung Institute, Imperial College London, London, UK., Kooperberg C; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA., Koskinen S; National Institute for Health and Welfare, Helsinki, Finland., Kovacs P; 1] Integrated Research and Treatment Center (IFB) Adiposity Diseases, University of Leipzig, Leipzig, Germany. [2] Department of Medicine, University of Leipzig, Leipzig, Germany., Kraja AT; Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, USA., Kumari M; Department of Epidemiology and Public Health, University College London, London, UK., Kuusisto J; Department of Medicine, Kuopio University Hospital and University of Eastern Finland, Kuopio, Finland., Lakka TA; 1] Kuopio Research Institute of Exercise Medicine, Kuopio, Finland. [2] Department of Physiology, Institute of Biomedicine, University of Eastern Finland, Kuopio Campus, Kuopio, Finland. [3] Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital and University of Eastern Finland, Kuopio, Finland., Langenberg C; 1] Medical Research Council (MRC) Epidemiology Unit, University of Cambridge, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK. [2] Department of Epidemiology and Public Health, University College London, London, UK., Le Marchand L; Epidemiology Program, University of Hawaii Cancer Center, Honolulu, Hawaii, USA., Lehtimäki T; Department of Clinical Chemistry, Fimlab Laboratories and School of Medicine, University of Tampere, Tampere, Finland., Lupoli S; 1] Department of Health Sciences, University of Milano, Milan, Italy. [2] Fondazione Filarete, Milan, Italy., Madden PA; Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA., Männistö S; National Institute for Health and Welfare, Helsinki, Finland., Manunta P; 1] Division of Nephrology and Dialysis, San Raffaele Scientific Institute, Milan, Italy. [2] Università Vita-Salute San Raffaele, Milan, Italy., Marette A; 1] Institut Universitaire de Cardiologie et de Pneumologie de Québec, Faculty of Medicine, Laval University, Quebec City, Quebec, Canada. [2] Institute of Nutrition and Functional Foods, Laval University, Quebec City, Quebec, Canada., Matise TC; Department of Genetics, Rutgers University, Piscataway, New Jersey, USA., McKnight B; Department of Biostatistics, University of Washington, Seattle, Washington, USA., Meitinger T; DZHK (Deutsches Forschungszentrum für Herz-Kreislauferkrankungen-German Research Centre for Cardiovascular Research), Munich Heart Alliance, Munich, Germany., Moll FL; Department of Surgery, University Medical Center Utrecht, Utrecht, the Netherlands., Montgomery GW; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Morris AD; Medical Research Institute, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK., Morris AP; 1] Estonian Genome Center, University of Tartu, Tartu, Estonia. [2] Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK. [3] Department of Biostatistics, University of Liverpool, Liverpool, UK., Murray JC; Department of Pediatrics, University of Iowa, Iowa City, Iowa, USA., Nelis M; Estonian Genome Center, University of Tartu, Tartu, Estonia., Ohlsson C; Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden., Oldehinkel AJ; Department of Psychiatry, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Ong KK; 1] Medical Research Council (MRC) Epidemiology Unit, University of Cambridge, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK. [2] MRC Unit for Lifelong Health and Ageing at University College London, London, UK., Ouwehand WH; 1] Department of Haematology, University of Cambridge, Cambridge, UK. [2] NHS Blood and Transplant, Cambridge, UK., Pasterkamp G; Experimental Cardiology Laboratory, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands., Peters A; 1] Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany. [2] DZHK (Deutsches Forschungszentrum für Herz-Kreislauferkrankungen-German Research Centre for Cardiovascular Research), Munich Heart Alliance, Munich, Germany. [3] Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany., Pramstaller PP; 1] Center for Biomedicine, European Academy Bozen, Bolzano (EURAC), Bolzano, Italy (affiliated institute of the University of Lübeck, Lübeck, Germany). [2] Department of Neurology, General Central Hospital, Bolzano, Italy., Price JF; Centre for Population Health Sciences, University of Edinburgh, Edinburgh, UK., Qi L; 1] Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA. [2] Department of Nutrition, Harvard School of Public Health, Harvard University, Boston, Massachusetts, USA., Raitakari OT; 1] Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland. [2] Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland., Rankinen T; Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, Louisiana, USA., Rao DC; 1] Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, USA. [2] Division of Biostatistics, Washington University School of Medicine, St. Louis, Missouri, USA. [3] Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA., Rice TK; 1] Division of Biostatistics, Washington University School of Medicine, St. Louis, Missouri, USA. [2] Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA., Ritchie M; Center for Systems Genomics, Pennsylvania State University, University Park, Pennsylvania, USA., Rudan I; 1] Centre for Population Health Sciences, University of Edinburgh, Edinburgh, UK. [2] Croatian Centre for Global Health, Faculty of Medicine, University of Split, Split, Croatia., Salomaa V; National Institute for Health and Welfare, Helsinki, Finland., Samani NJ; 1] Department of Cardiovascular Sciences, University of Leicester, Glenfield Hospital, Leicester, UK. [2] National Institute for Health Research (NIHR) Leicester Cardiovascular Biomedical Research Unit, Glenfield Hospital, Leicester, UK., Saramies J; South Carelia Central Hospital, Lappeenranta, Finland., Sarzynski MA; Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, Louisiana, USA., Schwarz PE; 1] Department of Medicine III, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany. [2] Paul Langerhans Institute Dresden, German Center for Diabetes Research (DZD), Dresden, Germany., Sebert S; Institute of Health Sciences, University of Oulu, Oulu, Finland., Sever P; International Centre for Circulatory Health, Imperial College London, London, UK., Shuldiner AR; 1] Program for Personalized and Genomic Medicine, University of Maryland School of Medicine, Baltimore, Maryland, USA. [2] Division of Endocrinology, Diabetes and Nutrition, University of Maryland School of Medicine, Baltimore, Maryland, USA. [3] Geriatric Research and Education Clinical Center, Vetrans Administration Medical Center, Baltimore, Maryland, USA., Sinisalo J; Helsinki University Central Hospital Heart and Lung Center, Department of Medicine, Helsinki University Central Hospital, Helsinki, Finland., Steinthorsdottir V; deCODE Genetics, Amgen, Inc., Reykjavik, Iceland., Stolk RP; Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Tardif JC; 1] Montreal Heart Institute, Montreal, Quebec, Canada. [2] Montreal Heart Institute, Université de Montréal, Montreal, Quebec, Canada., Tönjes A; 1] Integrated Research and Treatment Center (IFB) Adiposity Diseases, University of Leipzig, Leipzig, Germany. [2] Department of Medicine, University of Leipzig, Leipzig, Germany., Tremblay A; Department of Kinesiology, Laval University, Quebec City, Quebec, Canada., Tremoli E; Dipartimento di Scienze Farmacologiche e Biomolecolari, Università di Milano and Centro Cardiologico Monzino, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Milan, Italy., Virtamo J; National Institute for Health and Welfare, Helsinki, Finland., Vohl MC; 1] Institute of Nutrition and Functional Foods, Laval University, Quebec City, Quebec, Canada. [2] Department of Food Science and Nutrition, Laval University, Quebec City, Quebec, Canada., Amouyel P; Institut Pasteur de Lille, INSERM U744, Université de Lille 2, Lille, France., Asselbergs FW; 1] Institute of Cardiovascular Science, University College London, London, UK. [2] Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands. [3] Durrer Center for Cardiogenetic Research, Interuniversity Cardiology Institute Netherlands-Netherlands Heart Institute, Utrecht, the Netherlands., Assimes TL; Department of Medicine, Stanford University School of Medicine, Stanford, California, USA., Bochud M; 1] Institute of Social and Preventive Medicine (IUMSP), Centre Hospitalier Universitaire Vaudois (CHUV) and University of Lausanne, Lausanne, Switzerland. [2] Ministry of Health, Victoria, Republic of Seychelles., Boehm BO; 1] Division of Endocrinology, Diabetes and Metabolism, Ulm University Medical Centre, Ulm, Germany. [2] Lee Kong Chian School of Medicine, Imperial College London and Nanyang Technological University, Singapore., Boerwinkle E; Health Science Center at Houston, University of Texas, Houston, Texas, USA., Bottinger EP; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Bouchard C; Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, Louisiana, USA., Cauchi S; 1] CNRS UMR 8199, Lille, France. [2] European Genomic Institute for Diabetes, Lille, France. [3] Université de Lille 2, Lille, France., Chambers JC; 1] Ealing Hospital National Health Service (NHS) Trust, Middlesex, UK. [2] Department of Epidemiology and Biostatistics, Imperial College London, London, UK. [3] Imperial College Healthcare NHS Trust, London, UK., Chanock SJ; Division of Cancer Epidemiology and Genetics, National Cancer Institute, US National Institutes of Health, Bethesda, Maryland, USA., Cooper RS; Department of Public Health Sciences, Stritch School of Medicine, Loyola University of Chicago, Maywood, Illinois, USA., de Bakker PI; 1] Department of Medical Genetics, University Medical Center Utrecht, Utrecht, the Netherlands. [2] Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA. [3] Department of Epidemiology, University Medical Center Utrecht, Utrecht, the Netherlands., Dedoussis G; Department of Dietetics-Nutrition, Harokopio University, Athens, Greece., Ferrucci L; Translational Gerontology Branch, National Institute on Aging, Baltimore, Maryland, USA., Franks PW; 1] Department of Nutrition, Harvard School of Public Health, Harvard University, Boston, Massachusetts, USA. [2] Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University Diabetes Center, Skåne University Hospital, Malmö, Sweden. [3] Department of Public Health and Clinical Medicine, Unit of Medicine, Umeå University, Umeå, Sweden., Froguel P; 1] Department of Genomics of Common Disease, School of Public Health, Imperial College London, Hammersmith Hospital, London, UK. [2] CNRS UMR 8199, Lille, France. [3] European Genomic Institute for Diabetes, Lille, France. [4] Université de Lille 2, Lille, France., Groop LC; 1] Institute for Molecular Medicine, University of Helsinki, Helsinki, Finland. [2] Lund University Diabetes Centre, Lund University, Malmö, Sweden. [3] Diabetes and Endocrinology Unit, Department of Clinical Science, Lund University, Malmö, Sweden., Haiman CA; Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA., Hamsten A; Atherosclerosis Research Unit, Center for Molecular Medicine, Department of Medicine, Karolinska Institutet, Stockholm, Sweden., Hayes MG; Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA., Hui J; 1] PathWest Laboratory Medicine of Western Australia, Nedlands, Western Australia, Australia. [2] Pathology and Laboratory Medicine, University of Western Australia, Perth, Western Australia, Australia. [3] School of Population Health, University of South Australia, Adelaide, South Australia, Australia. [4] Sansom Institute for Health Research, University of South Australia, Adelaide, South Australia, Australia., Hunter DJ; 1] Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA. [2] Department of Nutrition, Harvard School of Public Health, Harvard University, Boston, Massachusetts, USA. [3] Department of Epidemiology, Harvard School of Public Health, Harvard University, Boston, Massachusetts, USA., Hveem K; Department of Public Health and General Practice, Norwegian University of Science and Technology, Trondheim, Norway., Jukema JW; 1] Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands. [2] Durrer Center for Cardiogenetic Research, Interuniversity Cardiology Institute Netherlands-Netherlands Heart Institute, Utrecht, the Netherlands. [3] Interuniversity Cardiology Institute of the Netherlands (ICIN), Utrecht, the Netherlands., Kaplan RC; Department of Epidemiology and Population Health, Albert Einstein College of Medicine. Belfer, New York, USA., Kivimaki M; Department of Epidemiology and Public Health, University College London, London, UK., Kuh D; MRC Unit for Lifelong Health and Ageing at University College London, London, UK., Laakso M; Department of Medicine, Kuopio University Hospital and University of Eastern Finland, Kuopio, Finland., Liu Y; Center for Human Genetics, Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA., Martin NG; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., März W; 1] Vth Department of Medicine (Nephrology, Hypertensiology, Endocrinology, Diabetology, Rheumatology), Medical Faculty of Mannheim, University of Heidelberg, Heidelberg, Germany. [2] Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz, Austria. [3] Synlab Academy, Synlab Services, Mannheim, Germany., Melbye M; 1] Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark. [2] Department of Medicine, Stanford University School of Medicine, Stanford, California, USA., Moebus S; Institute for Medical Informatics, Biometry and Epidemiology (IMIBE), University Hospital Essen, Essen, Germany., Munroe PB; 1] Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK. [2] Barts and The London Genome Centre, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Njølstad I; Department of Community Medicine, Faculty of Health Sciences, UiT The Arctic University of Tromsø, Tromsø, Norway., Oostra BA; 1] Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands. [2] Center for Medical Systems Biology, Leiden, the Netherlands. [3] Department of Clinical Genetics, Erasmus University Medical Center, Rotterdam, the Netherlands., Palmer CN; Medical Research Institute, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK., Pedersen NL; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Perola M; 1] Estonian Genome Center, University of Tartu, Tartu, Estonia. [2] National Institute for Health and Welfare, Helsinki, Finland. [3] Institute for Molecular Medicine, University of Helsinki, Helsinki, Finland., Pérusse L; 1] Institute of Nutrition and Functional Foods, Laval University, Quebec City, Quebec, Canada. [2] Department of Kinesiology, Laval University, Quebec City, Quebec, Canada., Peters U; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA., Powell JE; 1] Queensland Brain Institute, University of Queensland, Brisbane, Queensland, Australia. [2] University of Queensland Diamantina Institute, Translation Research Institute, Brisbane, Queensland, Australia., Power C; Centre for Paediatric Epidemiology and Biostatistics, University College London Institute of Child Health, London, UK., Quertermous T; Department of Medicine, Stanford University School of Medicine, Stanford, California, USA., Rauramaa R; 1] Kuopio Research Institute of Exercise Medicine, Kuopio, Finland. [2] Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital and University of Eastern Finland, Kuopio, Finland., Reinmaa E; Estonian Genome Center, University of Tartu, Tartu, Estonia., Ridker PM; 1] Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA. [2] Harvard Medical School, Boston, Massachusetts, USA., Rivadeneira F; 1] Department of Internal Medicine, Erasmus Medical Center, Rotterdam, the Netherlands. [2] Netherlands Consortium for Healthy Aging (NCHA), Rotterdam, the Netherlands. [3] Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands., Rotter JI; Institute for Translational Genomics and Population Sciences, Los Angeles BioMedical Research Institute at Harbor-University of California, Los Angeles Medical Center, Torrance, California, USA., Saaristo TE; 1] Finnish Diabetes Association, Tampere, Finland. [2] Pirkanmaa Hospital District, Tampere, Finland., Saleheen D; 1] Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK. [2] Center for Non-Communicable Diseases, Karatchi, Pakistan. [3] Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Schlessinger D; Laboratory of Genetics, National Institute on Aging, Baltimore, Maryland, USA., Slagboom PE; 1] Netherlands Consortium for Healthy Aging (NCHA), Leiden University Medical Center, Leiden, the Netherlands. [2] Department of Molecular Epidemiology, Leiden University Medical Center, Leiden, the Netherlands., Snieder H; Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Spector TD; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., Strauch K; 1] Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany. [2] Chair of Genetic Epidemiology, Institute of Medical Informatics, Biometry and Epidemiology, Ludwig Maximilians Universität, Neuherberg, Germany., Stumvoll M; 1] Integrated Research and Treatment Center (IFB) Adiposity Diseases, University of Leipzig, Leipzig, Germany. [2] Department of Medicine, University of Leipzig, Leipzig, Germany., Tuomilehto J; 1] National Institute for Health and Welfare, Helsinki, Finland. [2] Instituto de Investigacion Sanitaria del Hospital Universario La Paz (IdiPAZ), Madrid, Spain. [3] Diabetes Research Group, King Abdulaziz University, Jeddah, Saudi Arabia. [4] Centre for Vascular Prevention, Danube University Krems, Krems, Austria., Uusitupa M; 1] Department of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland. [2] Research Unit, Kuopio University Hospital, Kuopio, Finland., van der Harst P; 1] Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands. [2] Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands. [3] Durrer Center for Cardiogenetic Research, Interuniversity Cardiology Institute Netherlands-Netherlands Heart Institute, Utrecht, the Netherlands., Völzke H; 1] DZHK (Deutsches Zentrum für Herz-Kreislaufforschung-German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, Germany. [2] Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany., Walker M; Institute of Cellular Medicine, Newcastle University, Newcastle, UK., Wareham NJ; Medical Research Council (MRC) Epidemiology Unit, University of Cambridge, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK., Watkins H; 1] Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK. [2] Radcliffe Department of Medicine, Division of Cardiovascular Medicine, University of Oxford, Oxford, UK., Wichmann HE; 1] Chair of Epidemiology, Institute of Medical Informatics, Biometry and Epidemiology, Ludwig Maximilians Universität, Munich, Germany. [2] Klinikum Großhadern, Munich, Germany. [3] Institute of Epidemiology I, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany., Wilson JF; Centre for Population Health Sciences, University of Edinburgh, Edinburgh, UK., Zanen P; Department of Pulmonology, University Medical Center Utrecht, Utrecht, the Netherlands., Deloukas P; 1] Wellcome Trust Sanger Institute, Hinxton, UK. [2] William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK. [3] King Abdulaziz University, Jeddah, Saudi Arabia., Heid IM; 1] Department of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University of Regensburg, Regensburg, Germany. [2] Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany., Lindgren CM; 1] Broad Institute of MIT and Harvard University, Cambridge, Massachusetts, USA. [2] Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK., Mohlke KL; Department of Genetics, University of North Carolina, Chapel Hill, North Carolina, USA., Speliotes EK; 1] Department of Internal Medicine, Division of Gastroenterology, University of Michigan, Ann Arbor, Michigan, USA. [2] Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan, USA., Thorsteinsdottir U; 1] deCODE Genetics, Amgen, Inc., Reykjavik, Iceland. [2] Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Barroso I; 1] Wellcome Trust Sanger Institute, Hinxton, UK. [2] University of Cambridge Metabolic Research Laboratories, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK. [3] NIHR Cambridge Biomedical Research Centre, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK., Fox CS; National Heart, Lung, and Blood Institute, Framingham Heart Study, Framingham, Massachusetts, USA., North KE; 1] Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA. [2] Carolina Center for Genome Sciences, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Strachan DP; Division of Population Health Sciences and Education, St George's, University of London, London, UK., Beckmann JS; 1] Swiss Institute of Bioinformatics, Lausanne, Switzerland. [2] Department of Medical Genetics, University of Lausanne, Lausanne, Switzerland. [3] Service of Medical Genetics, CHUV University Hospital, Lausanne, Switzerland., Berndt SI; Division of Cancer Epidemiology and Genetics, National Cancer Institute, US National Institutes of Health, Bethesda, Maryland, USA., Boehnke M; Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA., Borecki IB; Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, USA., McCarthy MI; 1] Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK. [2] Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK. [3] Oxford NIHR Biomedical Research Centre, Oxford University Hospitals NHS Trust, Oxford, UK., Metspalu A; 1] Estonian Genome Center, University of Tartu, Tartu, Estonia. [2] Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia., Stefansson K; 1] deCODE Genetics, Amgen, Inc., Reykjavik, Iceland. [2] Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Uitterlinden AG; 1] Department of Internal Medicine, Erasmus Medical Center, Rotterdam, the Netherlands. [2] Netherlands Consortium for Healthy Aging (NCHA), Rotterdam, the Netherlands. [3] Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands., van Duijn CM; 1] Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands. [2] Netherlands Consortium for Healthy Aging (NCHA), Rotterdam, the Netherlands. [3] Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands. [4] Center for Medical Systems Biology, Leiden, the Netherlands., Franke L; Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Willer CJ; 1] Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan, USA. [2] Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, Michigan, USA. [3] Department of Human Genetics, University of Michigan, Ann Arbor, Michigan, USA., Price AL; 1] Broad Institute of MIT and Harvard University, Cambridge, Massachusetts, USA. [2] Department of Epidemiology, Harvard School of Public Health, Harvard University, Boston, Massachusetts, USA. [3] Department of Biostatistics, Harvard School of Public Health, Boston, Massachusetts, USA., Lettre G; 1] Montreal Heart Institute, Montreal, Quebec, Canada. [2] Montreal Heart Institute, Université de Montréal, Montreal, Quebec, Canada., Loos RJ; 1] Medical Research Council (MRC) Epidemiology Unit, University of Cambridge, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK. [2] Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA. [3] Genetics of Obesity and Related Metabolic Traits Program, Icahn School of Medicine at Mount Sinai, New York, New York, USA. [4] Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Weedon MN; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, UK., Ingelsson E; 1] Science for Life Laboratory, Uppsala University, Uppsala, Sweden. [2] Department of Medical Sciences, Molecular Epidemiology, Uppsala University, Uppsala, Sweden. [3] Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK., O'Connell JR; 1] Program for Personalized and Genomic Medicine, University of Maryland School of Medicine, Baltimore, Maryland, USA. [2] Division of Endocrinology, Diabetes and Nutrition, University of Maryland School of Medicine, Baltimore, Maryland, USA., Abecasis GR; Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA., Chasman DI; 1] Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA. [2] Harvard Medical School, Boston, Massachusetts, USA., Goddard ME; 1] Biosciences Research Division, Department of Primary Industries, Melbourne, Victoria, Australia. [2] Department of Food and Agricultural Systems, University of Melbourne, Melbourne, Victoria, Australia., Visscher PM; 1] Queensland Brain Institute, University of Queensland, Brisbane, Queensland, Australia. [2] University of Queensland Diamantina Institute, Translation Research Institute, Brisbane, Queensland, Australia., Hirschhorn JN; 1] Division of Endocrinology, Genetics and Basic and Translational Obesity Research, Boston Children's Hospital, Boston, Massachusetts, USA. [2] Broad Institute of MIT and Harvard University, Cambridge, Massachusetts, USA. [3] Department of Genetics, Harvard Medical School, Boston, Massachusetts, USA., Frayling TM; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, UK.
Publikováno v:
Nature genetics [Nat Genet] 2014 Nov; Vol. 46 (11), pp. 1173-86. Date of Electronic Publication: 2014 Oct 05.
Autor:
Fernández-Rhodes L; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, 137 East Franklin Street, Suite 306, Campus Box 8050, Chapel Hill, NC 27514-8050, USA. fernandez-rhodes@unc.edu, Demerath EW, Cousminer DL, Tao R, Dreyfus JG, Esko T, Smith AV, Gudnason V, Harris TB, Launer L, McArdle PF, Yerges-Armstrong LM, Elks CE, Strachan DP, Kutalik Z, Vollenweider P, Feenstra B, Boyd HA, Metspalu A, Mihailov E, Broer L, Zillikens MC, Oostra B, van Duijn CM, Lunetta KL, Perry JR, Murray A, Koller DL, Lai D, Corre T, Toniolo D, Albrecht E, Stöckl D, Grallert H, Gieger C, Hayward C, Polasek O, Rudan I, Wilson JF, He C, Kraft P, Hu FB, Hunter DJ, Hottenga JJ, Willemsen G, Boomsma DI, Byrne EM, Martin NG, Montgomery GW, Warrington NM, Pennell CE, Stolk L, Visser JA, Hofman A, Uitterlinden AG, Rivadeneira F, Lin P, Fisher SL, Bierut LJ, Crisponi L, Porcu E, Mangino M, Zhai G, Spector TD, Buring JE, Rose LM, Ridker PM, Poole C, Hirschhorn JN, Murabito JM, Chasman DI, Widen E, North KE, Ong KK, Franceschini N
Publikováno v:
American journal of epidemiology [Am J Epidemiol] 2013 Aug 01; Vol. 178 (3), pp. 451-60. Date of Electronic Publication: 2013 Apr 04.