Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Andrew C. Adams"'
Autor:
Andrew C. Adams, Jill A. Willency, Qian Yang, Keyun Qing, Xiaojun Wang, Minrong Ai, Alexander M. Efanov, Xiao-peng Yu, Andrea Renee Geiser, Paul J. Emmerson, Jianliang Lu, Jorge Alsina-Fernandez, Tamer Coskun, Brandy M. Snider, Emily C Beebe, Lili Guo
Publikováno v:
Journal of the Endocrine Society
Oxytocin (OXT) has been shown to suppress appetite, induce weight loss, and improve glycemic control and lipid metabolism in several species, including humans, monkeys, and rodents. However, OXT’s short half-life in circulation and lack of receptor
Autor:
Roel G. Vink, Edwin C. M. Mariman, Nadia J. T. Roumans, Marleen A. van Baak, Andrew C. Adams, Christine C. Cheng
Publikováno v:
International Journal of Obesity, 44(2), 544-547. Nature Publishing Group
Fibroblast growth factor 21 (FGF21) is an important regulator of energy metabolism. FGF21 is inactivated by fibroblast activation protein (FAP). We investigated whether FGF21 and/or FAP are secreted from human white adipose tissue of individuals with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf3354f99ae325826794c7826fc1bf53
https://cris.maastrichtuniversity.nl/en/publications/d399304b-d13d-4774-9dc4-fc5edf9c915e
https://cris.maastrichtuniversity.nl/en/publications/d399304b-d13d-4774-9dc4-fc5edf9c915e
Autor:
Pavlos Pissios, Xinyao Zhang, Alan J. Fish, Jeffrey S. Flier, Garima Singhal, Andrew C. Adams, Nicholas Douris, Eleftheria Maratos-Flier
Publikováno v:
Molecular Metabolism, Vol 5, Iss 8, Pp 690-698 (2016)
Molecular Metabolism
Molecular Metabolism
Objective Reproduction is an energetically expensive process. Insufficient calorie reserves, signaled to the brain through peripheral signals such as leptin, suppress fertility. Recently, fibroblast growth factor 21 (FGF21) was implicated as a signal
Autor:
Ricardo J. Samms, Christine C. Cheng, Andrew C. Adams, Patrick P. Antonellis, Dennis P. Smith, James W. Perfield, Ruth E. Gimeno, Alexei Kharitonenkov
Publikováno v:
Cell Reports, Vol 11, Iss 7, Pp 991-999 (2015)
SUMMARY A primary target of the pleiotropic metabolic hormone FGF21 is adipose tissue, where it initiates a gene expression program to enhance energy expenditure, an effect presumed to be centered on augmented UCP1 expression and activity. In UCP1 nu
Autor:
Francis J. P. Ebling, Andrew C. Adams, Alex Lory, Ricardo J. Samms, Perry Barrett, Jo E. Lewis, Scott Cooper, Jeni Luckett, Amy Warner, Maxine J Fowler, Dana Wilson, Kostas Tsintzas, Paul J. Emmerson, Alan C. Perkins
Hypothalamic tanycytes are considered to function as sensors of peripheral metabolism [1]. To facilitate this role, they express a wide range of receptors, including fibroblast growth factor receptor 1 (FGFR1). Using a monoclonal antibody (IMC-H7) th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a493ceadaadb8fede0c813eef39edec
https://nottingham-repository.worktribe.com/file/766645/1/CBpaper-repository.pdf
https://nottingham-repository.worktribe.com/file/766645/1/CBpaper-repository.pdf
Autor:
Perry Barrett, Ricardo J. Samms, Andrew C. Adams, Tamer Coskun, Maxine J Fowler, Francis J. P. Ebling, Alexei Kharitonenkov, Amy Warner, John M. Brameld, Michelle Murphy, Kostas Tsintzas, Matei Bolborea
Publikováno v:
Journal of neuroendocrinology. 25(2)
The present study aimed to investigate the actions of fibroblast growth factor 21 (FGF21) on energy balance in a natural model of relative fatness, the Siberian hamster. Hamsters were studied under long days (LD) to promote weight gain, or short days
Publikováno v:
American journal of physiology. Endocrinology and metabolism. 297(5)
In mice of normal weight and with diet-induced obesity, a high-fat, low-carbohydrate ketogenic diet (KD) causes weight loss, reduced circulating glucose and lipids, and dramatic changes in hepatic gene expression. Many of the effects of KD are mediat
Autor:
Carolyn A. Halstead, Vincent L. Reynolds, Sharon R. Myers, Holly W. Smith, Armando R. Irizarry, Alexei Kharitonenkov, Victor J. Wroblewski, Barbara C. Hansen, Andrew C. Adams, Jennifer A. Martin
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 6, p e65763 (2013)
PLoS ONE, Vol 8, Iss 6, p e65763 (2013)
Fibroblast growth factor 21 (FGF21) is a novel metabolic regulator that represents a promising target for the treatment of several metabolic diseases. Administration of recombinant wild type FGF21 to diabetic animals leads to a dramatic improvement i