Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Terri D. Lyddon"'
Autor:
N. Miranda Nebane, Yury V Kuzmichev, Elizabeth R. Wonderlich, Marc C. Johnson, Jonathan Richard, Susan M. Schader, Sarah Welbourn, Andrés Finzi, Corinne E. Augelli-Szafran, Vandana V. Gupta, Roger G. Ptak, Terri D. Lyddon, Carolyn A. Robinson, Robert Bostwick, Hwi Min Gil, Zhaohui Cai, Sam Ananthan, Lynn Rasmussen, David T. Evans
HIV-1 Vpu targets the host cell proteins CD4 and BST-2/Tetherin for degradation, ultimately resulting in enhanced virus spread and host immune evasion. The discovery and characterization of small molecules that antagonize Vpu would further elucidate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::09ea728eb1d665c2ecfc789c351c71ad
https://doi.org/10.1101/2021.07.30.454560
https://doi.org/10.1101/2021.07.30.454560
Autor:
Carolyn A. Robinson, Terri D. Lyddon, Hwi Min Gil, David T. Evans, Yury V. Kuzmichev, Jonathan Richard, Andrés Finzi, Sarah Welbourn, Lynn Rasmussen, N. Miranda Nebane, Vandana V. Gupta, Sam Ananthan, Zhaohui Cai, Elizabeth R. Wonderlich, Corinne E. Augelli-Szafran, Robert Bostwick, Roger G. Ptak, Susan M. Schader, Marc C. Johnson
Publikováno v:
Viruses; Volume 14; Issue 4; Pages: 817
HIV-1 Vpu targets the host cell proteins CD4 and BST-2/Tetherin for degradation, ultimately resulting in enhanced virus spread and host immune evasion. The discovery and characterization of small molecules that antagonize Vpu would further elucidate
Autor:
Mary LePique, Maddie Graham, Reinier Suarez, Clifton L. Ricana, Marc C. Johnson, Carolyn A. Robinson, Detlef Ritter, Terri D. Lyddon, Braxton Salcedo
Publikováno v:
Journal of Virology
In work with pathogenic viruses, it is useful to have rapid quantitative tests for viral infectivity that can be performed without strict biocontainment restrictions. A common way of accomplishing this is to generate viral pseudoparticles that contai
Publikováno v:
PLoS Pathogens, Vol 16, Iss 8, p e1008646 (2020)
PLoS Pathogens
PLoS Pathogens
Inositol hexakisphosphate (IP6) potently stimulates HIV-1 particle assembly in vitro and infectious particle production in vivo. However, knockout cells lacking inositol-pentakisphosphate 2-kinase (IPPK-KO), the enzyme that produces IP6 by phosphoryl
Autor:
Robert A. Dick, Clifton L. Ricana, John A. G. Briggs, Arianna M. Broad, Marc C. Johnson, J. Ryan Feathers, Florian K. M. Schur, Volker M. Vogt, Vladyslav Kravchuk, Chaoyi Xu, Juan R. Perilla, Dustin R. Morado, Terri D. Lyddon
Publikováno v:
PLoS Pathogens, Vol 16, Iss 1, p e1008277 (2020)
PLoS Pathogens
PLOS Pathogens
PLoS Pathogens
PLOS Pathogens
Retrovirus assembly is driven by the multidomain structural protein Gag. Interactions between the capsid domains (CA) of Gag result in Gag multimerization, leading to an immature virus particle that is formed by a protein lattice based on dimeric, tr
Autor:
Devon A. Gregory, Daniel Cyburt, Terri D. Lyddon, Yul Eum Song, Tiffany M Lucas, Marc C. Johnson
Publikováno v:
Viruses
Volume 10
Issue 10
Viruses, Vol 10, Iss 10, p 573 (2018)
Volume 10
Issue 10
Viruses, Vol 10, Iss 10, p 573 (2018)
The Human immunodeficiency virus-1 (HIV-1) accessory protein Vpu modulates numerous proteins, including the host proteins CD4 and BST-2/tetherin. Vpu interacts with the Skp, Cullin, F-Box (SCF) ubiquitin ligase through interactions with the F-Box pro
Autor:
Florian K. M. Schur, Chaoyi Xu, Marc C. Johnson, Owen Pornillos, Juan R. Perilla, Volker M. Vogt, Clifton L. Ricana, Jonathan M. Wagner, Robert A. Dick, Barbie K. Ganser-Pornillos, Kaneil K. Zadrozny, Terri D. Lyddon
Publikováno v:
Nature. 560(7719)
A short, 14-amino-acid segment called SP1, located in the Gag structural protein1, has a critical role during the formation of the HIV-1 virus particle. During virus assembly, the SP1 peptide and seven preceding residues fold into a six-helix bundle,
Publikováno v:
Journal of Virology. 87:1518-1527
Retroviruses, like all enveloped viruses, must incorporate viral glycoproteins to form infectious particles. Interactions between the glycoprotein cytoplasmic tail and the matrix domain of Gag are thought to direct recruitment of glycoproteins to nat
Publikováno v:
Journal of Virology. 86:4696-4700
We analyzed the nuclear trafficking ability of Gag proteins from six retroviral genera. Contrary to a previous report, human immunodeficiency virus type 1 (HIV-1) Gag showed no propensity to cycle through the nucleus. The only Gag protein that displa
Autor:
Clifton L. Ricana, Chaoyi Xu, Jonathan M. Wagner, Juan R. Perilla, Florian K. M. Schur, Barbie K. Ganser-Pornillos, Kaneil K. Zadrozny, Owen Pornillos, Robert A. Dick, Terri D. Lyddon, Volker M. Vogt, Marc C. Johnson
Publikováno v:
Nature
Information of the HIV-1 virus particle, a short, 14-amino acid segment called SP1, located in the Gag structural protein1, plays a critical role. During virus assembly the SP1 peptide and seven preceding residues fold into a six-helix bundle (6HB) t