Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Akihisa Kato"'
Autor:
Toshikatsu Kaburaki, Akihisa Kato, Yasushi Kawaguchi, Yoshihiro Urade, Atsuko Miki, Kenzui Taniue, Kentaro Kawata, Hidetoshi Kawashima, Rena Onoguchi-Mizutani, Shintaro Shirahama, Makoto Aihara, Nobuyoshi Akimitsu, Rie Tanaka
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-8 (2020)
Scientific Reports
Scientific Reports
Long non-coding RNAs (lncRNAs) play vital roles in the pathogenesis of infectious diseases, but the role of lncRNAs in herpes simplex virus 1 (HSV-1) infection remains unknown. Using RNA sequencing analysis, we explored lncRNAs that were highly expre
Autor:
Akihisa Kato, Tohru Natsume, Tomohisa Hatta, Hideo Kusano, Shinobu Kitazume, Shungo Adachi, Yasushi Kawaguchi, Yuhei Maruzuru, Ryota Sato, Naoto Koyanagi, Jun Arii, Shuichi Kawano, Mizuki Watanabe, Kousuke Takeshima
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Nature Communications
Nature Communications
Identification of the complete set of translated genes of viruses is important to understand viral replication and pathogenesis as well as for therapeutic approaches to control viral infection. Here, we use chemical proteomics, integrating bio-orthog
Autor:
Yoshitaka Nakayama, Yuhei Maruzuru, Akihisa Kato, Kosuke Takeshima, Yasushi Kawaguchi, Naoto Koyanagi, Yasuko Mori, Jun Arii
Publikováno v:
J Virol
During the nuclear export of nascent nucleocapsids of herpesviruses, the nucleocapsids bud through the inner nuclear membrane (INM) by acquiring the INM as a primary envelope (primary envelopment). We recently reported that herpes simplex virus 1 (HS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f998996a589bc413f2f1230ef214b5c7
https://europepmc.org/articles/PMC8791252/
https://europepmc.org/articles/PMC8791252/
Autor:
Toshiya Manabe, Tsuneo Ikenoue, Yusuke Murakami, Kensuke Miyake, Ryutaro Fukui, Kaiwen Liu, Jun Arii, Yoh Wada, Akihisa Kato, Ge-Hong Sun-Wada, Yun Zhang, Glen N. Barber, Yasushi Kawaguchi, Takahiko Chimura, Shin-ichiroh Saitoh, Ryota Sato, Takuma Shibata
Publikováno v:
Nature Immunology. 19:1071-1082
TLR3 is a sensor of double-stranded RNA that is indispensable for defense against infection with herpes simplex virus type 1 (HSV-1) in the brain. We found here that TLR3 was required for innate immune responses to HSV-1 in neurons and astrocytes. Du
Publikováno v:
J Virol
AIM2 is a cytosolic DNA sensor of the inflammasome, which induces critical innate immune responses against various invading pathogens. Earlier biochemical studies showed that the binding of AIM2 to DNA triggered the self-oligomerization of AIM2, whic
Autor:
Kosuke Takeshima, Yasushi Kawaguchi, Takeharu Minamitani, Naoto Koyanagi, Teruhito Yasui, Masayuki Shimojima, Mizuki Watanabe, Yuhei Maruzuru, Isao Kosugi, Ayano Fukui, Masaaki Oyama, Hiroko Kozuka-Hata, Yuji Kubota, Jun Arii, Yasuko Mori, Akihisa Kato, Mutsuhiro Takekawa
Publikováno v:
J Virol
Viral cell-to-cell spread, a method employed by several viral families for entrance via cell junctions, is highly relevant to the pathogenesis of various viral infections. Cell-to-cell spread of herpes simplex virus 1 (HSV-1) is known to depend great
Autor:
Jun Arii, Akihisa Kato, Yuta Shimanaka, Yasushi Kawaguchi, Naoto Koyanagi, Yasuko Mori, Hiroyuki Arai, Ayano Fukui, Yuhei Maruzuru, Nozomu Kono
Publikováno v:
J Virol
Glycerophospholipids are major components of cell membranes. Phosphatidylethanolamine (PE) is a glycerophospholipid that is involved in multiple cellular processes, such as membrane fusion, the cell cycle, autophagy, and apoptosis. In this study, we
Autor:
Kei Sato, Mai Suganami, Misato Shibazaki, Jumpei Ito, Kosuke Takeshima, Akihisa Kato, Yasushi Kawaguchi, Naoto Koyanagi, Yuhei Maruzuru
Publikováno v:
J Virol
Us3 proteins of herpes simplex virus 1 (HSV-1) and HSV-2 are multifunctional serine-threonine protein kinases. Here, we identified an HSV-2 tegument protein, UL7, as a novel physiological substrate of HSV-2 Us3. Mutations in HSV-2 UL7, which preclude
Publikováno v:
Journal of Virology. 90:10170-10181
Herpes simplex virus 1 (HSV-1) envelope glycoprotein D (gD) plays an essential role in viral entry. The functional regions of gD responsible for viral entry have been mapped to its extracellular domain, whereas the gD cytoplasmic domain plays no obvi
Publikováno v:
Journal of Virology. 90:8754-8767
To investigate the molecular mechanism(s) by which herpes simplex virus 1 (HSV-1) tegument protein UL51 promotes viral replication, we screened for viral proteins that interact with UL51 in infected cells. Affinity purification of tagged UL51 in HSV-