Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Adam J. Hume"'
Autor:
Judith Olejnik, Aditya Mithal, Esther Bullitt, Gustavo Mostoslavsky, Anne Hinds, Carlos Villacorta-Martin, Elke Mühlberger, Adam J. Hume, Jonathan Lindstrom-Vautrin
Publikováno v:
Stem Cell Reports
Summary Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection leading to coronavirus disease 2019 (COVID-19) usually results in respiratory disease, but extrapulmonary manifestations are of major clinical interest. Intestinal symptom
Autor:
Adam J. Hume, Elke Mühlberger
Publikováno v:
J Mol Biol
Research on filoviruses has historically focused on the highly pathogenic ebola- and marburgviruses. Indeed, until recently, these were the only two genera in the filovirus family. Recent advances in sequencing technologies have facilitated the disco
Autor:
Konstantinos-Dionysios Alysandratos, Eric J. Burks, Mary Lou Beermann, Ellen L Suder, Ruobing Wang, Esther Bullitt, Jessie Huang, Kristine M. Abo, Judith Olejnik, Chantelle Simone-Roach, Arjun Sharma, Elke Mühlberger, Adam J. Hume, Mohsan Saeed, Rhiannon B. Werder, Markus Bosmann, Jonathan Lindstrom-Vautrin, Darrell N. Kotton, Anne Hinds, Carlos Villacorta-Martin, Andrew A. Wilson, Finn Hawkins
Publikováno v:
Cell Stem Cell
bioRxiv
bioRxiv
A hallmark of severe COVID-19 pneumonia is SARS-CoV-2 infection of the facultative progenitors of lung alveoli, the alveolar epithelial type 2 cells (AT2s). However, inability to access these cells from patients, particularly at early stages of disea
Autor:
Elke Mühlberger, Emily V. Nelson, John H. Connor, Laure R. Deflubé, Adam J. Hume, Hideki Ebihara, Jennifer R. Pacheco, Tessa N. Cressey, John B. Ruedas
Publikováno v:
Antiviral Research. 146:21-27
Ebola virus (EBOV) causes a severe disease in humans with the potential for significant international public health consequences. Currently, treatments are limited to experimental vaccines and therapeutics. Therefore, research into prophylaxis and an
Autor:
Rachel Fearns, Tessa N. Cressey, Laure R. Deflubé, Friederike Feldmann, Elke Mühlberger, Judith Olejnik, Hideki Ebihara, Adam J. Hume, Elaine Haddock
Most nonsegmented negative strand (NNS) RNA virus genomes have complementary 3' and 5' terminal nucleotides because the promoters at the 3' ends of the genomes and antigenomes are almost identical to each other. However, according to published sequen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfa76127d0e9f0090b2eb58735c135d0
https://europepmc.org/articles/PMC6486738/
https://europepmc.org/articles/PMC6486738/
Autor:
Tessa N. Cressey, Whitney A. Manhart, Laure R. Deflubé, Elke Mühlberger, Adam J. Hume, Jennifer R. Pacheco
Publikováno v:
Cell Reports, Vol 24, Iss 10, Pp 2573-2580.e4 (2018)
Summary: Recently, traces of zoonotic viruses have been discovered in bats and other species around the world, but despite repeated attempts, full viral genomes have not been rescued. The absence of critical genetic sequences from these viruses and t
Autor:
Daisy W. Leung, Judith Olejnik, Elke Mühlberger, Gaya K. Amarasinghe, Adam J. Hume, Christopher F. Basler
Publikováno v:
Current Topics in Microbiology and Immunology ISBN: 9783319689463
Current Topics in Microbiology and Immunology
Marburg-and Ebolaviruses
Current Topics in Microbiology and Immunology
Marburg-and Ebolaviruses
This chapter describes the various strategies filoviruses use to escape host immune responses with a focus on innate immune and cell death pathways. Since filovirus replication can be efficiently blocked by interferon (IFN), filoviruses have evolved
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39384d661f839ebf9226a0309e79557c
https://doi.org/10.1007/82_2017_13
https://doi.org/10.1007/82_2017_13
Publikováno v:
Proceedings of the National Academy of Sciences. 106:16823-16828
Several different families of DNA viruses encode proteins that inactivate the cellular retinoblastoma tumor suppressor protein (pRb), which normally functions to bind E2F transcription factors and restrict expression of genes necessary for cellular p