Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Daire O'Shea"'
Autor:
Sarah C. Forester, John Lok Man Law, Donna N. Douglas, Michael Houghton, Gary Lund, Atul Humar, Mansun Law, Daire O'Shea, Joshua D. Lambert, David L.J. Tyrrell, Norman M. Kneteman, Adrian Egli, Dennis R. Burton
Publikováno v:
Liver Transplantation. 22:324-332
The anti-hepatitis C virus (HCV) activity of a novel monoclonal antibody (mAb; AR4A) and epigallocatechin gallate (EGCG) were studied in vitro using a HCV cell culture system and in vivo using a humanized liver mouse model capable of supporting HCV r
Autor:
Joerg Stelling, Michael Houghton, Thomas F. Mueller, Atul Humar, Luiz F. Lisboa, Lukas A. Widmer, Daire O'Shea, Adrian Egli, Deepali Kumar, Aliyah Baluch, Deanna M. Santer
Publikováno v:
The Journal of Infectious Diseases, 212 (1)
JOURNAL OF INFECTIOUS DISEASES
JOURNAL OF INFECTIOUS DISEASES
Background Influenza vaccine immunogenicity is suboptimal in immunocompromised patients. However, there are limited data on the interplay of T- and B- cell responses to vaccination with simultaneous immunosuppression. Methods We collected peripheral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::167fdf71a160cc0ca481b2c268359a8a
http://doc.rero.ch/record/303034/files/jiv015.pdf
http://doc.rero.ch/record/303034/files/jiv015.pdf
Publikováno v:
Transplantation. 95:448-455
BACKGROUND Data on how different immunosuppressive drugs affect cytomegalovirus (CMV)-specific T-cell responses may help guide more rational modification of immunosuppression in patients with CMV replication. We assessed the in vitro effects of indiv
Autor:
Xiao-Li Pang, Anders Åsberg, Daire O'Shea, Halvor Rollag, Atul Humar, D. L. Tyrrell, Luiz F. Lisboa, Deepali Kumar, Anders Hartmann, Adrian Egli
Publikováno v:
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 15(7)
Cytomegalovirus (CMV) encodes multiple microRNAs. While these have been partially characterized in vitro, their relevance to clinical CMV infection has not been evaluated. We analyzed samples from a cohort of solid organ transplant patients with CMV
Autor:
Khaled Barakat, Luiz F. Lisboa, Daire O'Shea, Atul Humar, Michael Houghton, Deanna M. Santer, D. Lorne Tyrrell, Rakesh Bhat, Adrian Egli, Karl P. Fischer, Aviad Levin, Brad S. Thomas, Michael A. Joyce, Deepali Kumar
Publikováno v:
The Journal of infectious diseases. 210(5)
BACKGROUND Feedback mechanisms between interferons α and λ (IFNs) may be affected by single nucleotide polymorphisms (SNP) in interleukin 28B (IL-28B; IFN-λ3) promoter region and may influence cytomegalovirus (CMV) replication. METHODS We associat
Autor:
Daire O'Shea, G. Farrell, Clair M. Gardiner, Markus Peck-Radosavljevic, Thomas Reiberger, Colm Bergin, C Keane
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e66831 (2013)
PLoS ONE
PLoS ONE
Pegylated-IFN and ribavirin remains the current treatment for chronic HCV infection in patients co-infected with HIV-1, but this regimen has low efficacy rates, particularly for HCV genotype 1/4 infection, has severe side effects and is extremely cos
Autor:
Leticia E. Wilson, Luiz Augusto Ferreira Lisboa, Adrian Egli, Luis G. Hidalgo, Moacyr Silva, Daire O'Shea, Deepali Kumar, Aliyah Baluch, Atul Humar
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 11, p e43937 (2012)
PLoS ONE, Vol 7, Iss 11, p e43937 (2012)
BACKGROUND: CMV-specific T-cells are crucial to control CMV-replication post-transplant. Regulatory T-cells (T-regs) are associated with a tolerant immune state and may contribute to CMV-replication. However, T-cell subsets such as T-regs and IL-17 p