Zobrazeno 1 - 10
of 43
pro vyhledávání: '"George Kemble"'
Autor:
Kanta Subbarao, Hong Jin, Elaine W. Lamirande, Xing Cheng, Fernando J. Torres-Velez, George Kemble, Grace L. Chen, Marlene Orandle
Publikováno v:
Journal of Virology. 88:2867-2876
H2 influenza viruses have not circulated in humans since 1968, and therefore a significant portion of the population would be susceptible to infection should H2 influenza viruses reemerge. H2 influenza viruses continue to circulate in avian reservoir
Autor:
Elaine W. Lamirande, Philana H. Liang, Hong Jin, Ji Young Min, Grace L. Chen, Bhagvanji Thumar, Catherine J. Luke, Bridget A. McMahon, Kathy L. Coelingh, Kanta Subbarao, George Kemble, Kawsar R. Talaat, Ruth A. Karron
Publikováno v:
Influenza and Other Respiratory Viruses. 7:66-73
Please cite this paper as: Talaat et al. (2012) An open-label phase I trial of a live attenuated H2N2 influenza virus vaccine in healthy adults. Influenza and Other Respiratory Viruses DOI: 10.1111/j.1750-2659.2012.00350.x. Background Live attenuated
Autor:
Yumiko Matsuoka, David E. Swayne, Leatrice Vogel, George Kemble, Hong Jin, Bin Lu, Ji-Young Min, Kanta Subbarao
Publikováno v:
Journal of Virology. 84:11950-11960
A live attenuated H7N7 candidate vaccine virus was generated by reverse genetics using the modified hemagglutinin (HA) and neuraminidase (NA) genes of highly pathogenic (HP) A/Netherlands/219/03 (NL/03) (H7N7) wild-type ( wt ) virus and the six inter
Publikováno v:
Journal of Virology. 84:7695-7702
H2 influenza viruses have not circulated in humans since 1968, and therefore a large segment of the population would likely be susceptible to infection should H2 influenza viruses reemerge. The development of an H2 pandemic influenza virus vaccine ca
Publikováno v:
Virology. 398(1):109-114
We studied the attenuation, immunogenicity and efficacy of the cold-adapted A/Ann Arbor/6/60 (AA ca) (H2N2) virus in mice and ferrets to evaluate its use in the event of an H2 influenza pandemic. The AA ca virus was restricted in replication in the r
Autor:
Li-Mei Chen, Purvi D. Desai, Yumiko Matsuoka, Hong Jin, Michael Marino, Kanta Subbarao, George Kemble, Ruben O. Donis, Amorsolo L. Suguitan, David E. Swayne
Publikováno v:
Virology. 395(2):280-288
A recombinant live attenuated influenza virus DeltaH5N1 vaccine with a modified hemagglutinin (HA) and intact neuraminidase genes from A/Vietnam/1203/04 (H5N1) and six remaining genome segments from A/Ann Arbor/6/60 (H2N2) cold-adapted (AA ca) virus
Autor:
Catherine J. Luke, Bhagvanji Thumar, Kawsar R. Talaat, Ruth A. Karron, Karen Callahan, Amorsolo L. Suguitan, George Kemble, Josephine M. McAuliffe, Kathleen L. Coelingh, Kimberly Mills, Hong Jin, Susan C. DiLorenzo, Brian R. Murphy, Elizabeth Schappell, Kanta Subbarao, Elaine W. Lamirande, Grace L. Chen
Publikováno v:
Vaccine. 27:4953-4960
Development of live attenuated influenza vaccines (LAIV) against avian viruses with pandemic potential is an important public health strategy.We performed open-label trials to evaluate the safety, infectivity, and immunogenicity of H5N1 VN 2004 AA ca
Autor:
Catherine J. Luke, Brian R. Murphy, Grace L. Chen, Hong Jin, Karen Callahan, Elaine W. Lamirande, Kanta Subbarao, George Kemble, Ruth A. Karron, Susan C. DiLorenzo, Kathy L. Coelingh, Kawsar R. Talaat
Publikováno v:
Vaccine. 27:3744-3753
Background Live attenuated influenza vaccines (LAIVs) are being developed and tested against a variety of influenza viruses with pandemic potential. We describe the results of an open-label Phase I trial of a live attenuated H7N3 virus vaccine. Metho
Autor:
Laura Gillim-Ross, Hong Jin, George Kemble, Zhongying Chen, Kanta Subbarao, Celia Santos, Amy Aspelund
Publikováno v:
Journal of Virology. 83:65-72
Avian influenza A virus A/teal/HK/W312/97 (H6N1) possesses seven gene segments that are highly homologous to those of highly pathogenic human influenza H5N1 viruses, suggesting that a W312-like H6N1 virus might have been involved in the generation of
Autor:
Zhongying Chen, Amy Aspelund, Hong Jin, Celia Santos, Laura Gillim-Ross, Kanta Subbarao, Dan Ye, Chin-Fen Yang, George Kemble
Publikováno v:
Journal of Virology. 82:10854-10863
Influenza pandemic preparedness has focused on influenza virus H5 and H7 subtypes. However, it is not possible to predict with certainty which subtype of avian influenza virus will cause the next pandemic, and it is prudent to include other avian inf