Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Alfredo Castello"'
Autor:
Louisa Iselin, Alan Wainman, Richard M. Parton, Jane A. McKeating, Marko Noerenberg, Mary Kay Thompson, Alfredo Castello, William James, Ilan Davis, Aino I. Järvelin, Daniel Agranoff, Natasha Palmalux, Dalia Gala, Jeffrey Y. Lee, Josh Titlow, Peter A C Wing, Xiaodong Zhuang
SummaryDespite an unprecedented global research effort on SARS-CoV-2, early replication events remain poorly understood. Given the clinical importance of emergent viral variants with increased transmission, there is an urgent need to understand the e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90c9c0ea5d984a6e3e1055ee23dbf95d
https://doi.org/10.1101/2021.06.29.450133
https://doi.org/10.1101/2021.06.29.450133
Autor:
Ilan Davis, Peter J. Ratcliffe, Alfredo Castello, William James, Jeffrey Y. Lee, Maria Prange-Barczynska, Marko Noerenberg, Jane A. McKeating, Craig Thompson, Senko Tsukuda, Koichi Watashi, Isobel L.A. Argles, Thomas P. Keeley, Sophie B. Morgan, Peter A C Wing, Samvid Kurlekar, Kuan-Ying A. Huang, Xiaodong Zhuang, Timothy S. C. Hinks, Tammie Bishop, Peter Balfe, Emma J. Hodson, Adam Harding
Publikováno v:
Cell Reports
Cell Reports, Vol 35, Iss 3, Pp 109020-(2021)
Cell Reports, Vol 35, Iss 3, Pp 109020-(2021)
COVID-19, caused by the novel coronavirus SARS-CoV-2, is a global health issue with more than 2 million fatalities to date. Viral replication is shaped by the cellular microenvironment and one important factor to consider is oxygen tension, where hyp
Autor:
Natasha Johnson, Berati Cerikan, Shabaz Mohammed, Manuel Garcia-Moreno, Javier Martinez, Christopher J. Neufeldt, Alfredo Castello, Ralf Bartenschlager, Mohamed Kammoun, Jeffrey Y. Lee, Anna Andrejeva, Mirko Cortese, Marko Noerenberg, Honglin Chen, Kathryn S. Lilley, Ilan Davis, Michael L. Knight, Aino I. Järvelin, Ni Shuai, Wael Kamel, Michael J. Deery
Publikováno v:
Molecular Cell
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes COVID-19. SARS-CoV-2 relies on cellular RNA-binding proteins (RBPs) to replicate and spread, although which RBPs control its life cycle remains largely unknown. Here, we employ a mul
Autor:
Wael Kamel, Maximilian Hannan, Alfredo Castello, Vincenzo Ruscica, Louisa Iselin, Samantha Moore, Manuel Garcia-Moreno, Javier Martinez, Ilan Davis, Shabaz Mohammed, Marko Noerenberg, Aino I. Järvelin, Natasha Palmalux, Andres Merits
Publikováno v:
bioRxiv
The expansion of tropical mosquito habitats and associated arboviruses is a risk for human health, and it thus becomes fundamental to identify new antiviral strategies. In this study we employ a new approach to elucidate the composition of the ribonu
Publikováno v:
Seminars in Cell & Developmental Biology
Highlights • Proteomic studies have uncovered more than a thousand cellular proteins that are present in the particles of RNA viruses. • Strikingly, nearly four hundred of these are RNA-binding proteins (RBPs). • Several virion-incorporated RBP
Hypoxic and Pharmacological Activation of HIF Inhibits SARS-CoV-2 Infection of Lung Epithelial Cells
Autor:
Maria Prange-Barczynska, Senko Tsukuda, William James, Tammie Bishop, Thomas P. Keeley, Koichi Watashi, Xiaodong Zhuang, Ilan Davies, Jane A. McKeating, Peter A C Wing, Emma J. Hodson, Peter J. Ratcliffe, Isobel L.A. Argles, Peter Balfe, Kuan-Ying A. Huang, Samvid Kurlekar, Timothy S. C. Hinks, Sophie B. Morgan, Alfredo Castello Palomares, Craig Thompson, Jeffrey Y. Lee, Marko Noerenberg
Publikováno v:
SSRN Electronic Journal.
COVID-19, caused by the novel coronavirus SARS-CoV-2, is a global health issue with more than 1 million fatalities to date. Understanding how host factors modify the viral life cycle could inform susceptibility to viral infection and the design of ne
Autor:
Marcel Bach-Pages, Victoria Cox, Svenja Hester, Luis Carrasco, T. P. Davis, Marko Noerenberg, Thibault J. M. Sohier, Miguel Angel Sanz, Alfredo Castello, Caroline E. Lenz, Rosario Avolio, Manuel Garcia-Moreno, Shabaz Mohammed, Vicent Pelechano, Bingnan Li, Esther González-Almela, Aino I. Järvelin, Emiliano P. Ricci, Shuai Ni, Bernd Fischer
The compendium of RNA-binding proteins (RBPome) has been greatly expanded by the development of RNA-interactome capture (RNA-IC). However, it remains unknown how responsive is the RBPome and whether these responses are biologically relevant. To answe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11930326133c58287c2358df424805a9
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
Throughout a viral infection, the infected cell reprograms the gene expression pattern in order to establish a satisfactory antiviral response. African swine fever virus (ASFV), like other complex DNA viruses, sets up a number of strategies to evade
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56d249a0aff5e7b4f3ddba117146cb9e
http://hdl.handle.net/10261/95308
http://hdl.handle.net/10261/95308