Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Victoria Majam"'
Autor:
Gabrielle Walsh, Wenshuo Zhou, Alexei Medvedev, Barbara K. Felber, Sanjai Kumar, Jasper Perry-Anderson, Victoria Majam, Konstantin Virnik, Ira Berkower
Publikováno v:
Biochem Biophys Res Commun
There is an urgent need for a malaria vaccine that can prevent severe disease in young children and adults. Despite earlier work showing an immunological mechanism for preventing infection and reducing disease severity, there is currently no reliable
Autor:
Bradley Hickey, Robin Mere, Sanjai Kumar, Meng Shi, John B. Sacci, Thomas C. Luke, Maria F. Baraceros, Peter Hobart, Lorraine Soisson, Ronald A. Nosek, Jennifer Ng, Judith E. Epstein, Keith Limbach, Yupin Charoenvit, Nancy O. Richie, Ruobing Wang, Mara P. Berzins, Denise L. Doolan, Esteban Abot, Tanya G. Geter, Lolita Bebris, Joao C. Aguiar, Jo Glenna Banania, Richard C. Hedstrom, David E. Lanar, Michael R. Hollingdale, William O. Rogers, Daniel Freilich, Harini Ganeshan, Victoria Majam, Martha Sedegah, Thomas L. Richie, Patricia de la Vega, Stephen L. Hoffman, Jon Norman
Publikováno v:
Human Vaccines & Immunotherapeutics
When introduced in the 1990s, immunization with DNA plasmids was considered potentially revolutionary for vaccine development, particularly for vaccines intended to induce protective CD8 T cell responses against multiple antigens. We conducted, in 19
Autor:
Victoria Majam, Chris F. Ockenhouse, Thomas L. Richie, Daniel J. Carucci, Mara P. Berzins, Judith E. Epstein, Kent E. Kester, Stephen L. Hoffman, Joe Cohen, Harini Ganeshan, Jennifer Ng, Trevor R. Jones, Ruobing Wang, Rhonda Newcomer, D. Gray Heppner, Yupin Charoenvit, Nadia Tornieporth, Esteban Abot, Steve Fitzpatrick, Carolyn A. Holland, Jon Norman, C.Nicole Freydberg
Publikováno v:
Vaccine. 22:1592-1603
Optimal protection against malaria may require induction of high levels of protective antibody and CD8(+) and CD4(+) T cell responses. In humans, malaria DNA vaccines elicit CD8(+) cytotoxic T cells (CTL) and IFNgamma responses as measured by short-t
Autor:
Martha Sedegah, John B. Sacci, Kalpana Gowda, Sanjai Kumar, Victoria Majam, John A. Tine, Peter Hobart, Richard C. Hedstrom, Yupin Charoenvit, Stephen L. Hoffman, Walter R. Weiss
Publikováno v:
The Journal of Immunology. 164:5905-5912
Intramuscular immunization with a naked DNA plasmid expressing the Plasmodium yoelii circumsporozoite protein (pPyCSP) protects mice against challenge with P. yoelii sporozoites. This protection can be improved either by coadministration of a plasmid
Autor:
Maria Belmonte, Victoria Majam, Yupin Charoenvit, Stephen L. Hoffman, Trevor R. Jones, William O. Rogers, Denise L. Doolan, Martha Sedegah, Minh Lu, Gary T. Brice, Daniel J. Carucci, Arnel Belmonte
Publikováno v:
Infection and immunity. 70(7)
The persistence of immunity to malaria induced in mice by a heterologous DNA priming and poxvirus boosting regimen was characterized. Mice were immunized by priming with DNA vaccine plasmids encoding thePlasmodium yoeliicircumsporozoite protein (PyCS
Autor:
Stephen L. Hoffman, Joao C. Aguiar, William O. Rogers, Victoria Majam, Richard C. Hedstrom, Yupin Charoenvit, David E. Lanar, John B. Sacci, Richard Stout
Publikováno v:
Vaccine. 20(1-2)
We compared the needle free jet device device Biojector with syringe/needle as a method to administer a DNA vaccine encoding the Plasmodium falciparum circumsporozoite protein (PfCSP) in albino rabbits. A group of three rabbits was injected by the in