Zobrazeno 1 - 10
of 31
pro vyhledávání: '"K. MacDonald"'
Publikováno v:
Journal of the Canadian Association of Gastroenterology. 4:189-191
Background Obtaining steroid-free remission in Ulcerative Colitis (UC) is a clinically important parameter that can mitigate the development of disease-related complications and lead to improved quality of life. Aims A systematic review to assess the
Systematic review: disease activity indices for immune checkpoint inhibitor-associated enterocolitis
Autor:
Joshua Chang, Brian G. Feagan, Niels Vande Casteele, Vipul Jairath, John K MacDonald, Christopher Ma, Tran M Nguyen
Publikováno v:
Alimentary pharmacologytherapeuticsREFERENCES. 55(2)
BACKGROUND Although there is interest in developing pharmacotherapies for the treatment of immune checkpoint inhibitor-associated enterocolitis (ICIC), there is currently no consensus on how to optimally measure disease activity in this condition. AI
Autor:
Geert R. D'Haens, Joshua Chang, Malcolm Hogan, Jurij Hanzel, Niels Vande Casteele, William J. Sandborn, Christopher Ma, Robert Battat, Vipul Jairath, Guangyong Zou, Brian G. Feagan, Eileen Crowley, John K MacDonald, Rocio Sedano, Tran M Nguyen, Parambir S. Dulai, Siddharth Singh
Publikováno v:
Journal of Crohn's & colitis, 16(2), 224-243. Elsevier
Background and Aims Quantifying placebo rates and the factors influencing them are essential to inform trial design. We provide a contemporary summary of clinical, endoscopic, histological and safety placebo rates in induction and maintenance clinica
Publikováno v:
The Cochrane Library
Cochrane Database Syst Rev
Cochrane Database Syst Rev
Background Oral 5-aminosalicylic acid (5-ASA) preparations were intended to avoid the adverse effects of sulfasalazine (SASP) while maintaining its therapeutic benefits. Previously, it was found that 5-ASA drugs in doses of at least 2 g/day, were mor
Autor:
Morris Gordon, Neeraj Narula, Tran M Nguyen, Nilesh Chande, M Ellen Kuenzig, Brian G. Feagan, Siddharth Singh, John K MacDonald
Publikováno v:
Inflamm Bowel Dis
The Cochrane Inflammatory Bowel Diseases Group presented a symposium at Digestive Diseases Week 2019 entitled “Medical Management Following Surgical Therapy in Inflammatory Bowel Disease: Evidence from Cochrane Reviews”. This article summarizes t
Autor:
Eytan Wine, M Chen, P Medvedev, Matthew W Carroll, J Wu, Cheryl Kluthe, K MacDonald, Hien Q. Huynh, Justine M. Turner, Diana R. Mager, Kerry Siminoski
Publikováno v:
European Journal of Clinical Nutrition. 72:623-626
Suboptimal vitamin D (vitD) status and reduced lean body mass are highly prevalent in pediatric inflammatory bowel diseases (IBD). The study objective was to determine sarcopenia prevalence and associations with vitD status in newly diagnosed pediatr
Autor:
John K MacDonald, Claire E Parker, Joana Torres, Brian G. Feagan, Nilesh Chande, Ray Boyapati, James E. East
Publikováno v:
Inflammatory bowel diseases. 25(3)
A symposium organized by the Cochrane IBD Group and presented at the 2017 Digestive Disease Week annual meeting reviewed the recent literature on several controversial topics in inflammatory bowel disease (IBD) management including the efficacy of or
Autor:
Claire E Parker, Mahmoud Mosli, Reena Khanna, Nadia Mohammed Vashist, Guangyong Zou, Sigrid Nelson, Brian G. Feagan, John K MacDonald, Vipul Jairath, Mark A Samaan
Publikováno v:
The Cochrane Library
BACKGROUND: Endoscopic assessment of mucosal disease activity is routinely used to determine eligibility and response to therapy in clinical trials of ulcerative colitis. The operating properties of the existing endoscopic scoring indices are unclear
Publikováno v:
Journal of the Canadian Association of Gastroenterology. 2:288-289
AIMS: To assess the safety and efficacy of oral 5-aminosalicylic acid (5-ASA) for induction and maintenance of remission in patients with ulcerative colitis (UC). METHODS: We searched MEDLINE, EMBASE, and CENTRAL from inception to May 2018. Randomize
Autor:
Stephen J. Bickston, John K MacDonald, Mahmoud Mosli, Brian G. Feagan, David J. Tsoulis, Brian W Behm, Reena Khanna, Jianfeng Cheng
Publikováno v:
Inflammatory Bowel Diseases. 21:1151-1159
Background We performed a systematic review to evaluate the efficacy and safety of vedolizumab for induction and maintenance of remission in ulcerative colitis. Methods A literature search to June 2014 identified all applicable randomized trials. Out